Bioassay techniques such as enzyme-linked immunosorbent assay (ELISA) or bead-based flow cytometry use labeled reagents to detect and monitor biomolecular interactions, typically providing results that are representative of a fixed point in time.
Label-free technology instead uses impedance- or optics-based biosensors to measure the changes that occur upon analyte binding to a ligand immobilized on a biosensor surface. This approach enables the interaction to be monitored in real-time without artificial manipulation of the individual assay components.
In the following video Dr. Tatiana Tiago, Product Manager at Creoptix, explains what label-free technology means for Drug Discovery and what the benefits of this approach are compared to traditional bioassay techniques.
► Label-Free Technology: www.creoptix.com/technologies...
► Grating-Coupled Interferometry: www.creoptix.com/technologies...
► WAVEsystem: www.creoptix.com/products
► About Creoptix: www.creoptix.com/about-us
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Creoptix AG
Zugerstrasse 76
8820 Waedenswil
Switzerland
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Creoptix Inc.
c/o CliftonLarsonAllen LLP
111 South Bedford Street, Ste. 108
MA-01803 Burlington
USA