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It’s so difficult to describe depression to someone who’s never been there because it’s not sadness.

What pisses me off is the fact that I never had depression, I had a little bit of anxiety from the pressures of college and I was put on Zoloft. The doctor said it helps with anxiety. Well that was the beginning of a miserable 15 year journey of being on and off antidepressants and benzos, being mean, ruining relationships. You name it I did it on that medicine. I'm off everything now and have been for 11 weeks. Little bit of benzo withdrawal left but nothing serious. I've had it. The drug companies and pill pushing family doctors along with the psychiatrists need to be held accountable.

For me the main factor making me feel depressed had always been the inherent stupidity and pettiness of the representatives of human kind and the fact that it's everywhere I look and go. As soon as I get away from any signs of human presence, I feel better immediately, without the use of any drugs.

I appreciate the study but I'm with John here on the triple barrel questions. How did we think of it before and why has it been pushed for so long? We need scientific facts for mental health not theories.

Taking psilocybin mushrooms helped me deal with my depression and anxiety. Since I started taking them I have noticed clearer thinking and peaceful existence. Taking on anything life throws at me, it has really helped me.

I was on SSRI for severe depression for years. They didn't work so now I'm treating my depression without meds. I do supplements and healthy diet and it works much better.

News like this revelation really pisses me off because I and everyone else that lives with depression have been chemically treated with the wrong thing all of these years! No wonder we never really feel better

Big pharma can't be happy about this.

Depression is due to difficult life experiences. Guidance and support to help you through these challenges is what is needed. Not drugs.

I’m really bummed that the guest speaker got cut off at a really important time when he was speaking. I was really interested in what he had to say!

I think the people who make money off of people being sick knew this a long time ago.

"I recently purchased the mushroom product from Dr.healingstrain and I am extremely satisfied with my purchase. The product works exactly as advertised and has exceeded my expectations. The customer service was also top-notch. I highly recommend this product to anyone in need of a solution to their anxiety or depression problems "

Depression is a big deal

this is my spin on this.... i think living in an America causing a much more environmentally depression and that why the meds dont always work compared to some people who may have a chemical imbalance. life isnt so ment to be cooped up all day and beaten down at a job and things shouldnt be a struggle for basic things like food and heatlh care.

For me, personally, I always felt that what I experienced has more to do with dopamine than serotonin.

This was presented in a deliberately vague way, with the predictable pharmaceutical lobbyist as a "guest" for a corporate media channel that relies on funding & ad revenue from pharmaceutical adverts.. What this doesn't say is that it isn't just any "study" it is a comprehensive umbrella review of around 550 peer reviewed studies and investigative reviews of other studies, each reviewing many other studies. They broke down the 550 studies to get down to 17 high quality meta-analyses, some which themselves analysed studies involving 150,000 people over a period of years. So they looked at all this information, going back decades, encompassing 100s of thousands of people across multiple studies & meta analysis's of multiple studies and other meta analyses. And came to the the conclusion that there is no convincing evidence that depression is caused by low serotonin. Even in studies where serotonin was deliberately reduced by environmental factors, it didn't convincingly show an increase in depression. In many cases there was evidence that showed that long term use can in fact reduce serotonin levels (in the same way long term supplementation of Melatonin decreases production of melatonin, as the body does what is most efficient) . Rather the comprehensive study suggests that depression is a reaction to external & environmental factors, economic factors, past trauma, daily stresses, current stresses, loss, loneliness, existential dread etc. As someone who has tried numerous antidepressants that never ever worked, i can say truthfully that while i tried them for depression & anxiety, i was never as suicidal as i was on antidepressants. Particularly that of Aropax, which was later banned as it was proven to increase suicidal ideation in much the same way that Zoloft was. Of interest is the fact that many different SSRIs are in fact basically the same as older versions, just tweaked slightly to renew the patents, even though it is effectively the same medicine. And this goes for even banned medicines like Aropax. Throughout my years i went on them, off them, changed to different types, & went off them, SSRIs, Triciclics, SNRIs, & SSRIs again, but the side affects & numbness of emotion, the dry mouth & lack of concentration, occasional shakes & dizziness, & the complete reduction of libido, were always worse. And of course i knew what was the cause of my depression, & that was my reality of having been fostered, plus having no roots & no family, plus later having gone through an earthquake that destroyed much of what was dear to me, of the places & vibrant scene in my city that i came to be a part of & the base of the family of friends that i met along the way.. I tried many SSRIs to try to balance out the symptoms of all that, but always found the same conclusion, that for me at least, the side affects were worse.. But what ultimately worked for me was a combination of meditation, exercise, therapy, magnesium to reduce muscle tension, Chicken bone broth, working on my own issues, & adrenalin inducing activities that force me to focus on the moment like Downhill MTB or skateboarding, particularly Downhill MTB.. I know some people that SSRIs worked for, but many that they had the opposite affect, & others who became essentially addicted, & it was largely no different coming off them than any other addictive drug that also alters brain chemistry.. From my experience, & my own long suspicion, this huge meta analysis of many other meta analysis's, the gold standard of reviews, vindicates my own experience & thoughts on these drugs.. And my suspicion of the profit motive pushing what is best for the profit motive rather than focusing on root causes..

Is life and being a adult a cause of depression???

Clinical depression found in the hospital is a much much more serious phenomena than found in the community. What people describe as depression i the community is generally dissatisfaction with their lives. They may have genuine reasons to be dissatisfied but a doctor cannot treat this with a tablet. Which is why I feel sorry for them.

I was on prozac years ago, & found that my fear/anxiety level dropped. I became psychologically unstable & became suicidal due to feeling no fear. I have a passive personality but I also started getting verbally aggressive & showed a lack of empathy. I told the doctor about it, & they just ignored me, & told me it was an environmental problem & carry on taking them. 😡

He may have helped you understand it, but he sure didn't help me understand it. I learned absolutely nothing from that interview.

Some people may have actual imbalances. But most of us aren't born with depression, it's something that develops from the environment we're in and can become chronic if left without care. I'm only speaking for myself, but my depression and anxiety disorder didn't develop until my emotional, mental, and spiritual needs were neglected for many years in my environment with a combination of complex events throughout my life that I could not control all the time or get away from. And having adopted a unhealthy mindset from family and external influences, I wasn't aware how harmful it is/was, it just was how things were. I wonder if depression starts, you know like a snow ball when one or a mix of emotional, mental, physical, and spiritual needs aren't met and it just get's worse as needs continue to be unmet. And it's even harder when it starts at a young age. The Dalai lama said, "Love and compassion are necessities, not luxuries. Without them humanity cannot survive." At first I didn't fully understand this, but as I got older, it's true on a mirco and macro scale.

This was an incredibly vague and completely unhelpful segment in terms of what it was trying to do: educate anyone about anything A single four sentence paragraph could have expressed everything in this pathetic segment

I am a woman in my thirties who has been suffering from Post SSRI Sexual Dysfunction (PSSD) for 8 years, one of the many people ruined by SSRIs who don't know how to recover their sexuality and all that revolved around it (no small feat!). There are young people in the PSSD community who have taken their own lives because of the syndrome. Many have taken SSRI drugs for mild issues and are now ruined. There needs to be a lot more focus on this topic...PSSD could happen to anyone who takes SSRIs, because with current knowledge it is not predictable, the etiology is not even known, and there is no cure. Patients are trying to raise money for scientific research because they are abandoned by the health care system that has harmed them instead of making them better. It is an absurd reality from many points of view.

For me I've always thought SNRI's worked better for myself than SSRI. In fact, SSRI would often cause depersonalization for me whenever I tried it. I'm curious as to why SSRI's have been prescribed for so long then? What does it do that it has somehow worked against depression? Does increasing Serotonin levels in the brain generally uplift the mood as a side-effect?

What needs to be changed: All the medical textbooks and medical board exams What can't be changed: The millions of doctors already indoctrinated. millions of doctors

“Probably not a placebo” wow real confident in that answer huh.

They've never known even how they work, just all of the side effects such things bring on.

There are two kinds of depression. One is situational depression which is depression brought on by insurmountable problems in your life and the inability to fix them. The other kind is inbalance chemical depression. Medications do not work on the first one. Until you get your problems actually fixed, the pill will not do anything

I switched from Psychology to Nursing because there's just too much guesswork in Psychology. Nursing is an actual science.

I have always thought depression was caused by hormone imbalance.

SSRIs messed me up badly in terms of diet/weight/sexual health, and I didn’t see progress for years until I got a different, more thorough diagnosis and was put on antipsychotics. That was 8 months ago and my life has dramatically improved. I know ssris work for others in my life but for those with undiagnosed bipolar (etc) they can sure make things even tougher in some ways.

For more than 80 years, we have been hearing about the two hormones serotonin and dopamine that you cut cause depression. How is that now? They say that the reason is not from these two hormones???. What made them change their opinion of this? Research, old medicines and medicines are all thrown in the trash? I am surprised by all this talk. How did they change this view of depression?

SSRIS didn’t help me with depression. It feels more like it works for sadness. People who are depressed will become a zombie

Depression is caused by politicians and corporations who make our lives disgusting.

I wish schools would start teaching how meditation, exercise and being in nature can help minimize/cure your depression. All they want to do is get ppl addicted to 💊 💊 💊

I suffer from extreme depression every day. I was sexually abused and raped by a woman when I was 10 years old. I have been blamed and made to feel terrible about it, I don't think my parents would love me if I told them. Every day my thoughts haunt me sometimes to the point of a panic attack.

I’ve been on Lexapro (an SSRI) before and it did not help at all. I’m currently on Wellbutrin and I’ve been feeling better

Nothing is going to change. Way too much money is being made selling SSRIs.

Then I want the thousands of dollars I spent on antidepressants that were supposedly adjusting my serotonin levels back.

Study funded by antidepressants making company.

if it's not related to Serotonin, how come the SSRI do work? because they work...

Not sure this clip was even helpful. This "new" study shows depression isn't linked to low serotonin. They didn't provide any new information here as what to do about depression knowing this information. It's all the same...talk therapy, try different SSRI's til you find one that works, or "other" treatment options....but they didn't say what those other treatment options are. It's just the same ol', same ol'....

It's a placebo effect folks. No significant differences were shown in the drug trials.

I know many people taking anti-depressants and the meds don’t work for them. None of them had any talk therapy to go along with the meds.

Not at all surprising. %15 reported improvement in trials is all it needs to qualify. Just 15! SSRI’s have never been the solution

after 12 years still have PSSD caused by just 2 weeks of taking SSRI citalopram

I have experienced depression at different times in my life. Antidepressants never worked for me. One in particular gave me the suicidal thoughts when I took it. I am off all Antidepressants now and I'm going to stay that way. Other thi gs that helped me was quitting the stressful job I had because the boss constantly on my case about stupid petty things. I felt better when I quit my job. I could sleep in the mornings, dress how I wanted too, I could shop or go out for a coffee with a friend. One day I went to the beach all by myself. These things lift my spirits when I did them. Working a job sucks every bit of joy out of me because of that one particular boss who is always making the work day miserable. Does anyone know what trying to say??

@CBS News Why report on this? You gave the impression that if serotonin plays no part in depression, then there is no reason to take SSRI’s. I will give you credit for at least saying that if it seems to work for you, keep taking it. This was an overly simplistic overview of some of the neurotransmitters involved involved. I worry that do to this shotty reporting, people who really need to be in SSRI’s will either not seek help (due to you talking about placebo affect and not finishing that discussion), or will stop taking it. Please, be more responsible and do better!

They knew it the whole time ! We are the product ….

Tate was right all along

Thank you, as a person who struggles with bipolar disorder this is a eye opener, no one has the right answer.

Mushrooms is the answer 🙏

Sooo...psychological experts, what was the point of this? Why would you announce this to the public if it entails nothing but "keep doing exactly what you're doing?"

I can not take SSRIs , I have tried 4 and had adverse reactions to all of them.

Then I expect an apology and refund for all SSRI treatment the past five years.

If depression inside out is anger then anti depressants make you…angry? 😅make it make sense 🎉

FULL STOP 🛑 Shut up! My child almost killed her self because SSRIs drawback the risk is suicide and self harm! This should not be legal. That have no justification giving these for teens and young adults!

Talk therapy doesn’t do anything for someone that is severely depressed. It’s like talking to a person that has autism and expecting them to be less autistic after therapy… i always cringe when people say I overcame depression by meditating and talk therapy… than that person obviously didn’t have a severe depressive disorder that comes from the brain. We need a medication like psilocybin that changes the neural networks of the brain. Or better yet, I hope in the future we can Find a way to prevent severe depression all together. As of currently nothing is really working. Mostly bc the limitations the FDA puts on new interventions, procedures and medications. Years to get to market …

Would have been better if this gentleman had not been cut off. If the SSRIs aren't really helping, what's causing the depression to improve when people take them? What strategy might be more effective? Please provide thumbnail sketches on how these meds work.

They NEVER thought it was the ONLY reason. Scientists are not that simple-minded.

They should be a way of testing the level of this neurotransmitter before administering any drug. The organ malfunctioning in depression is the brain. They should be a way of scanning and analysing the brain to diagnose any kind of depression.

We need a more serious look @ the use of psychedelics to treat depression

That doc couldn't be more vague, could he?

I’ve been saying depression isn’t a chemical Imbalace to my doctors for years.. Maybe now they’ll listen 🙄

Would you link the study so people can critique it? Any controversy regarding the outcome or the conclusions drawn?

Depression is pretty much what “fatigue” is to the body. There are a million gradations in severity, and too many causes to list. No wonder some modalities work for some people, but not all work for all people.

I feel depression is caused by a situation of suffering that (one feels) will never change or cannot be changed, but also has come to a place were it is unendurable. Anti-depressants seem to make a person care less- a temporary solution but not a good one. Natural endorphins are far better, and fitness is a secondary benefit.

I'm coming off anti depressants and I already feel happier 😁

They make me have worse suicidal thoughts

100% true, we need way more research in this area! I have drug resistant depression, this basically means that if I take drugs they don’t really help my depression, but I then have to suffer with loads of side effects! After years of bouncing from drug to drug and experiencing ever side effect going, I eventually got off it all and just have CBT (cognitive behavioural therapy) and DBS (Deep Brain Stimulation). The DBS has by far been the best thing that has ever happened to me, the only problem is I can only have this treatment for brief periods of time, then I have to go through a break period… The effects do taper off over time, but it’s horrible to be ‘normal’ while in the treatment phase, then gradually declining mental health until I can have another round. But DBS has been an absolute life saver!

It’s weird how people still act surprised when they realize that low serotonin is a symptom and not a cause of depression

Antidepressants treat the pain of depression, but they do not cure the feeling of guilt or treat the anguish of loneliness.

We have other neurotransmitters. Low levels of Dopamine are a real problem as well.They should test your levels before prescribing SSRIs .Sadly ,the majority of doctors don't do this.

Did no one think, hey lets have a Blood test to prove its chemical?

Give me a break! I mean, for 30 or 40 years the SSR's were effective and there was lot of evidence that they worked ok. Now, just out nowhere, we are told that all these prescriptions had no real effect, or if they had any, they still don't know what was going inside our brains. This is terrifying news for those who have depression. I mean, it's just like playing Poker, you never know what's going to happen,

Medical Marijuana works for one of my friends.

American Psychological Association what a joke. Backed by pharmaceuticals.

It's a gut issue. Gaba.....why else do they call the poison gabapentin etc.....we have been lied to for decades from cancer to colds.

I understand the studies , but Sertraline as helped me greatly

Inequality is the root of all depression. The lesser the divisions of rich/poor , male /female etc will be, the better the deptessive situations will improve.

i believe because SSRI had not worked for my anxiety-depression problem that I had been on SSRI since last 25 years.

How does a pharmaceutical drug prescribed to “treat” depression that is known to potentially cause suicidal impulses make it to market?

Men, be VERY careful of dating women who are taking Wellbutrin... especially if alcohol is consumed. Trust me, know what meds your female partner is taking and be cautious of Wellbutrin in particular.

So what did the study find exactly...? What methods were used?

I have depression and I don't know if that's right or not goodbye

Why are the medications to treat clinical depression so effective and popular then?

Whenever someone is struggling to treat their depression symptoms, it's REALLY important for them to be making well informed and responsible decisions about their health. _(for reasons we don't really need to discuss here)_ *IF YOU HAVE DEPRESSION:* Please know this news segment is being presented in an irresponsibly misleading way.

He didnt give proper explanation about what is Serotonin. It's a mood elevator, and it also helps in good sleep etc.

And of course pharmaceutical companies are paying him to push the new drugs for profit 📈 🙄

new study suggests depression is not caused by low levels of serotonin, wow isn't that something else isn't this? This is why you clicked on this video, correct? To hear about the study I heard him talking about serotonin, possibly having nothing to do with peoples depression, but heard nothing at all about their "" study.

“We lost you there.” Right. That was the pharmaceutical company live editing his comments.

Not in all, but in MOST cases of depression and/or anxiety I have seen in variety of people is the result of their socio-economic position in society--not in a chemical imbalance in the brain. If people's needs are met, if they are free from abuse and soul killing jobs, etc., if they have a real chance at self-actualisation, they may feel depressed or anxious at some points in their lives, but it will never be a constant battle for them. All the medical profession is doing is pushing "legal" drugs to solve problems that users of Illegal drugs do, Either way, whoever the makers are of the drugs, legal or illegal, they are the ones benefiting from selling the drugs, not the poor sods who get talked into taking the drugs because we are all taught from childhood to "trust" people in certain professions. The truth is everyone needs to seriously question what the "experts" are telling them and do their own research to find out what exactly the experts are pushing on the patients and WHO really benefits from being on antidepressants for 40 or 50 years. Hint: it is not the patients who benefit.

Sounds like the reporter is on ssri 😂

Maybe depression is caused by to much serotonin did they ever think of that?

Strange how diet and lifestyle were not even addressed. I had three different friends who became addicted to diet coke and all three developed bi-polar conditions that required medications. Other friends would not touch the stuff because of what we have all observed. Coincidence I hardly think so. I THINK THERE IS A DIRECT LINK BETWEEN WHAT I HAVE JUST STATED.

Thanks for the video. Is there an SSRI that can help with sleep issues ???

Times I had been seriously depressed: after amalgam filling fell out, after tooth with amalgam filling was extracted, during heavy metal chelation. So Hg redistribution causes it for me, strangely Hg exposure doesn't. Otherwise I can be going through tough times and I will stay optimistic, but not when Hg is involved, then my adrenals don't function right, and I have zero tolerance for stress.

It's caused by nuerological problems. Mine is caused by nuerological problems which were caused by environmental illnesses. The ssri s just masked the symptoms but the bacteria and environmental illnesses just got worse.

Once you start studying the relationship of food on your wellbeing psycoactive substances like alcohol, cafeïne and theïne, you will see that it doesnt make any sense to use medicine or prescriptions. There are literally hundreds of substances directly from nature that can naturally help tame your anxiety, these are usually very healthy. It's not hard to find them.