Dr. Robert Weinberg - "Cancer Stem Cells: A New Target in the Fight Against Cancer"

Рет қаралды 53,611

Whitehead Institute for Biomedical Research

12 жыл бұрын

Whitehead Institute Member Robert Weinberg's keynote address from the 2011 Whitehead Colloquium, November 5, 2011.

Пікірлер: 21

@sameerdixit2561 12 жыл бұрын

Just amazing, how in 1 hr 19 mins I got to know what i was working on for over a month!!

@alz123alz 7 жыл бұрын

Beautiful informative lecture.Thank you for your book, the biology of Cancer.

@leeondene 5 жыл бұрын

Still the same conversations been had maybe some progression of course but we still don't have kinder treatments that work on the metabolism of cancer Stem cells

@Lindibigwi 11 жыл бұрын

Actually, I'm graduating this year from Cancer biology Master's and I'm keen to go ahead with a PhD

@sasastanimirovic8765 11 жыл бұрын

R.Weinberg is a primus inter pares.

@campina9143 3 жыл бұрын

amazing, stunning... wow

@Lindibigwi 11 жыл бұрын

However, R. Weiberg is the origin of my interest in cancer research (more precisely his "hallmarks of cancer, 2000")+all lab directors should be like him towards their students. Their work on EMT is interesting.

@vanderbilt4918 11 жыл бұрын

See that's interesting. I'm a year shy of earning my PharmD, and the thought of doing an oncology research Master's on the side has tickled my mind over the last couple of years. For me it very much depends on how promising the prospective breakthroughs look over the next couple of decades or so -- can you comment a little bit on this for me as a Cancer Biology major? I would really appreciate it. Thanks.

@sumerpatil22 9 жыл бұрын

Can someone please provide the link for the research article referred at 07:50 ? The reference mentioned below figure is not readable. Thank you :)

@PrinceofHope1 12 жыл бұрын

How I wished I was taking 7.012 in MIT (though I was so much younger then)

@fearlessonmyheart 10 жыл бұрын

Where can I found the papers swowed ?

@tonywang7734 9 жыл бұрын

EMT is now well known to be correlated to the production of CSCs. However, something to keep in mind is that EMT might only cause the adoption of SC markers: CD24/CD44, SC gene expression, morphology, but whether the cells themselves are actually stem cells in vitro and in vivo remains to be tested. Something else to think about is if EMT creates stem cells from epithelial breast cancer cells and mesenchymal (not stem) cells from epithelial cells in development, what caused the obvious difference. Where does the parallel end?

@jordantaylor276 9 жыл бұрын

Tony Wang Actually, I wonder if you could clarify. Almost any definition of mesenchymal cells includes 'stem' or at least multipotency as a part, so I've always been confused about this distinction between cancer cells having undergone EMT, and CSCs. What's up with that?

@brcarter1111 6 жыл бұрын

difficult to say if EMT is causative or symptomatic of CSC transformation.

@Lindibigwi 11 жыл бұрын

I still have a lot to learn+ there are still things I don't get, but to me, "cancer initiating cells" are a consequence (=agressiv evolution) of cancer but definitly not the origin of it. The name they give to these cells is the only new concept but the phenotype of these cells could not have been a mystery for so long...