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That's so sweet of you. But physiology Jyada nhi aati mujhe

@@DrGobindRaiGarg Sir, you're so humble to say this statement. 🙏🙏

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So sweet of you. Thanks a lot

So sweet of you. Thanks a lot

@@DrGobindRaiGarg welcome 💝🖤

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So sorry dear for the delay. You can find videos of entire Pharmacology on my App

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So sweet of you. Shukriya

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Doc is endothelin antagonists like bosentan

Aspirin + clopidogrel

Endothelin it self is a vasoconstrictor...

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During development, megakaryobalsts have nucleus, which produce many enzymes, mature platelets don't contain

@@DrGobindRaiGarg thqnku sir

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Sir I want to purchase your all full length video lectures... Sir prepladder is not for me bcoz I am faculty of pharmacology... I don't need videos of all subject. So sir please guide me what should I do.

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We see if it is possible

It’s not like that

Couldn't understand your question

Sorry sir I commented on only see half video but in the in end my doubt is Cristal clear that for eractile function we have to use for topically

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It is of 15 months

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@@DrGobindRaiGarg sir why PGE1 works like PGE2 is there any reason behind it to work ?

Chemically they are quite similar naa

@@DrGobindRaiGarg ok sir and TQ so much

Couldn't understand your question

@@DrGobindRaiGarg sir during experiments we will use this terms PA2 and Values to estimate potency of agonists and antagonists but what is the full form of those terms what the letters n numbers indicate, why we are using log values ...

Okay. Got it Like pH, which is negative logarithm of H+ conc. pA2 and pD2 are negative logarithms. The value of pA2 is a negative logarithm of the molar concentration of competitive antagonist, which requires a doubling of the concentration of agonist to compensate for the action of the antagonist. The meaning of pA2 is the affinity of the antagonist to the receptor. So in pA2. p means negative log, A is concentration of antagonist required. 2 means agonist is required in x2 dose. Similarly The negative logarithm of the EC50 of an agonist is called pEC50 or pD2 (old term). It indicates the potency of an agonist but not its efficacy, the higher pD2, reflects higher potency of the agonist.

@@DrGobindRaiGarg what about log values sir , why we prefer always log values, another doubt also sir why we never say adrenaline as parasympatholytic drug , however adrenaline action is opp. to ACH

@@DrGobindRaiGarg pA2 , u mentioned x2 dose ,what does x indicates

Available in different video

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