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Genetic alterations play a crucial role in the development and progression of lymphomas. These alterations can involve changes in the DNA of lymphocytes, the white blood cells that normally help fight infections. In lymphomas, these genetic changes can lead to uncontrolled growth and survival of abnormal lymphocytes. Common genetic alterations in lymphomas include chromosomal translocations, where parts of different chromosomes break off and join together incorrectly.
Understanding these genetic alterations is important for diagnosing lymphomas and developing targeted therapies that can specifically target the abnormal pathways driving the cancer cells' growth. Advances in genetic research continue to improve our ability to classify and treat different types of lymphomas based on their specific genetic profiles.
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Dr. K.C. Goutham Reddy, Senior Consultant Medical Oncologist, Karkinos Healthcare, Hyderabad, briefs us on the Genetic Alterations of Lymphoma.
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