How did the rest of your ochem classes go?

They often don't. They know chemistry like the back of their hand and they sometimes teach as if you should already know this stuff. I hate it !

@@shanemichael9404 Ikr

I know it's been awhile, but I was just curious; how did the rest of your class go?

@@PunmasterSTP awful but I passed with a B, and I’m in medical school now. I never have to look at another dumb ochem reaction again. All’s well that ends well.

@@ClicClikBang I'm glad you passed, and I wish you the best with medical school! Also, yeah, I don't think ochem is going to come up in there...

If i had a professor this hot i'd never be missing classes. NEVER.

Guys! He's our teacher! It's not fine to speak like this!

dafaqs wrong with you

😂😂

but for real tho!

congrats! thanks for watching!

True

Lol In india we have to learn 100x more than this, in high school lmao

@@NEETAspirant-li3tu Fact buddy,,,, + maths & phy tooo

@@andy0695 yup, pretty much XD what a pain in the ass

+Hunter Goodreau my great pleasure! tell your classmates!

I know it's been awhile, but how did your exam go?

How did your exam go?

How'd the rest of Orgo 2 go?

Are you still taking ochem or did you finish that up? And if so, how did the rest of it go?

Grignard is a very famous reagent, & It just simply used in most of reaction to proceed and formation of different compounds ... Btw you have a good name ! 😅😊

How'd the rest of ochem go?

I know it's been awhile, but how did your final go?

+Simmy Matharu good to know! i should litter some more comments over there then!

A subtle form of product placement? ;)

I know it's been awhile but I was just curious; what did you get your degree in?

+Kelly Burns my pleasure! spread the good word!

it's a workup step, after the reaction is complete a little ammonium chloride or something similar will just protonate all the oxyanions. but yes you're correct we can't literally add protons, H+ is short hand for acid, something that is a source of protons. even a weak acid will protonate oxyanions to get the alcohol product as they are so basic.

haha i know! i commented on that video to tell them that pentavalent carbon is the biggest cardinal sin in organic chemistry.

Maybe they'd had a bit of the alcohol they'd been talking about, eh? ;P

a spoil sport indeed! it's a very common solvent.

Edit: We did use it :) Nothing caught fire. Also thanks for the video, came back to it trying to understand the mechanism. Think I have it now, formed triphenylmethanol from bromobenzene and bromophenone (I think).

Smart professor. Ether is just nasty stuff and for people who aren't disciplined with safety or well-organized and attentive to the dates of their chemicals, ether just isn't a good choice. Need to also think about how the chemicals are disposed afterwards. Real headaches.

Oh I remember that, yeah they showed a pentavalent carbon intermediate, definitely not accurate. The precise way it happens is not fully understood, but it's gotta be some kind of oxidative addition, very common in inorganic chemistry.

legend says he's able to turn H2O into wine!

How did your exams go?

and i love you!

that's aqueous workup! the oxyanion has formed so the grignard reaction is complete, then you just toss in some aqueous ammonium chloride or some other weak acid to protonate and get the alcohol product.

correct! preparation of grignard reagent, which will then do grignard reactions.

so that's just the aqueous workup step, in the lab you would do the grignard in anhydrous conditions and you get oxyanions in solution, then work up with aqueous ammonium chloride or something when you're done which will go and protonate everything to give the alcohol product.

oh, I see now! Thanks for the prompt reply :) have a good evening!

yes indeed!

Yes water will destroy a Grignard reagent so the reaction must be carried out in strictly anhydrous conditions.

+agent475816 i would beg to differ! lots of evidence to the contrary. like the proposed six membered ring transition state involving two grignard reagents. also, it seems like if it had a formal charge, there'd be too much opportunity for intramolecular reactions, skeletal rearrangements, etc. i can find nothing online supporting the idea of a formally charged grignard reagent, do you have a source?

+agent475816 i've never seen anything like that mechanism for grignard reagent formation in the kahn video, and i'm extremely dubious. carbon is strictly tetravalent, so picking up an additional electron goes against everything i've ever seen in organic chemistry. textbooks may say the reagent reacts "like a carbanion", but the key word is like, the bond is polar covalent, to our best knowledge.

Professor Dave Explains There are carbanions formed in lots of reactions. The Birch reduction is a good example. Another is the acidity of terminal alkynes. React a terminal alkyne with NaNH2, and you will get a terminal sp hybridized carbanion with Na+ on it. You may be right, I'm just going off what I learned in my class and that Khan Academy videos and your videos.

carbanions yes, but always with three bonds and a lone pair, never four bonds plus a radical, that i've ever seen anyway. carbon can't accommodate five coordination sites.

Professor Dave Explains But that is what it is in the grignard reagent. It is very unstable, that is why the halogen is kicked off, and the magnesium donates it's second electron to form the carbanion with 3 bonds like in the video. You are saying that that is not correct?

in this situation it's no problem! but yes, no acidic conditions for grignards.