In the past decade, Chile has actively promoted the establishment of expansive marine protected areas, including the Nazca-Desventuradas Marine Park, the Juan Fernández Sea Protected Area, and the Juan Fernández Marine Park. These areas are among the largest marine protected zones globally. The biodiversity in these regions exhibits a remarkable level of endemism, with around half of the species found exclusively in these notable locations and nowhere else on the planet. The #SEPacificSeamounts expedition aims to explore deeper and less-charted waters, anticipating the discovery of new species and contributing valuable insights into these distinctive ecosystems, underscoring the global significance of this little-explored part of the world.