Here's What DNA Really Looks Like

  Рет қаралды 318,131

SciShow

SciShow

Күн бұрын

There’s more to DNA than just the double helix we know and love: under some conditions this familiar molecule can take on unfamiliar forms, each of which can have a different impact on our health.
Hosted by: Hank Green
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Sources:
General overviews of alternate DNA structures:
www.intechopen.com/books/dna-...
www.ncbi.nlm.nih.gov/books/NB...
people.bu.edu/mfk/restricted56...
B-DNA and history of the double helix:
www.nature.com/scitable/topic...
A-DNA:
journals.iucr.org/q/issues/19...
Z-DNA:
www.nature.com/articles/s4200...
H-DNA:
www.pnas.org/content/pnas/101...
G-quadruplexes:
www.ncbi.nlm.nih.gov/pmc/arti...
Image Sources:
commons.wikimedia.org/wiki/Fi...
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Пікірлер: 647
@besmart
@besmart 3 жыл бұрын
I don't know why I am choosing to fact-check this in the comments, but 1 meter of DNA per cell is the length of the haploid genome. We have a diploid genome, and each cell actually holds 2 m of DNA. Great video!
@littledudefromacrossthestr5755
@littledudefromacrossthestr5755 3 жыл бұрын
Nani
@browerkyle
@browerkyle 3 жыл бұрын
Destin**, I think we all welcome good fact checks! Can we see a video of yours exploring how to pull DNA from a sample? Edit: Sorry, Joe! Too many 'smart' channels, but I suppose that's a good problem to have!
@minnymouse4753
@minnymouse4753 3 жыл бұрын
Did you see their video why corgi mixes always look like corgis ..she mentioned mRNAs can fall back to the main genome and duplicate genes More evidence pretty much case in point all bets are off for Lamerkism
@BothHands1
@BothHands1 3 жыл бұрын
ty!!
@HN-kr1nf
@HN-kr1nf 3 жыл бұрын
oml 2 of my favourite science channels :D
@danielm.1441
@danielm.1441 3 жыл бұрын
A G-Quadruplex sounds like a wrestling move...
@alexanderjohnson2309
@alexanderjohnson2309 3 жыл бұрын
Hahahaha!
@davetoms1
@davetoms1 3 жыл бұрын
*Announcer 1:* "Going up to the top turnbuckle." *Announcer 2:* "High risk for high reward." *Announcer 1:* "Is it...? What is...?! GOOD LORD!" *Announcer 2:* _"A G-QUADRUPLEX FROM THE TOP ROPE! THIS MATCH IS OVER"_ *Referee:* "1... 2... 3!!!" *Announcer 1:* "And the champ retains their title!" *Announcer 2:* "And The Mitochondria is _still_ the powerhouse of the cell!"
@UKFX
@UKFX 3 жыл бұрын
If you're a yank or 7 yeara old, sure.
@baronvonbeandip
@baronvonbeandip 3 жыл бұрын
@@UKFX or if you have any culture at all, yeah.
@electronresonator8882
@electronresonator8882 3 жыл бұрын
not a processor chip?
@kjth2003
@kjth2003 3 жыл бұрын
Every cell in my body knows how to replicate DNA, but my brain wasn't let in on the secret so I've had to spend years studying it!
@rayzen9534
@rayzen9534 3 жыл бұрын
@rrobertt13 that like saying u dont know how to reproduce but u exist because ur parents knew😭🤣
@Brahmdagh
@Brahmdagh 3 жыл бұрын
@@rayzen9534 Which is accurate?
@RAMBO14001
@RAMBO14001 3 жыл бұрын
Wow that's almost.. poetic lol
@kjth2003
@kjth2003 3 жыл бұрын
@rrobertt13 obviously I was anthropomorphising it for the sake of my joke... I know how cells work (I have a BSc in molecular biology, worked in a genetics lab for over 4.5 years and I'm now doing my MSc in Clinical Bioinformatics (Genomics) 😂😂)
@MagicToadSlime
@MagicToadSlime 3 жыл бұрын
@@kjth2003 its almost like your original comment was humorous in nature
@larkmacgregor3143
@larkmacgregor3143 3 жыл бұрын
As a molecular biologist myself (RNA Pol II is my bailiwick) , the next time someone asks me to explain why the common form of the genetic material is called "B-DNA", I am going to refer them to this video. Hank, you and your team do a terrific job of explaining how things work in a clear fashion without getting bogged down in technical minutiae. Thanks for all you do to help educate people about a subject that is complex in a way that is easily understood. You are awesome!
@larkmacgregor3143
@larkmacgregor3143 3 жыл бұрын
@rrobertt13 Ooo, I know this one! Because your two floppy disc drives were A: and B:, respectively. At least I'm young enough to not have learned to use a computer when data was stored on punch cards 🤣.
@larkmacgregor3143
@larkmacgregor3143 3 жыл бұрын
@rrobertt13 Ummm . . . in case one died? Actually, I read on the HP website that one was for running programs and the other was for data. That sounds like the stone age now, doesn't it?
@jonahs92
@jonahs92 3 жыл бұрын
@rrobertt13 I always assumed the C stood for "computer" or something like that....
@rickkwitkoski1976
@rickkwitkoski1976 3 жыл бұрын
@rrobertt13 THAT! Is EASY to explain!!!!!
@rickkwitkoski1976
@rickkwitkoski1976 3 жыл бұрын
@rrobertt13 Welll... it all had to start SOMEwhere!!! Dijda ever boot up from a tape drive? A "cassette" tape drive? Start the boot process... go boil water and make "drip filtered" coffee... come back to your desk stirring the coffee... sit down and have a sip or two... look out the window a bit.... OH! It's up and ready! PLEASE DON'T CRASH!!!
@WillsWei
@WillsWei 3 жыл бұрын
1:22 It’s called right or left handed because if you align your 4 fingers with the twists of the helix, your thumb will point in the direction of the helix for only one of your hands, and that hand is the “handedness” of the helix
@musashi939
@musashi939 3 жыл бұрын
Thought so too. Although not sure if this is a here exactly the case since I never read about that before. I got the association from electro magnetism. Same with cosmology. For the same reason our solar system spins counter clockwise. Determine the northpole and check the direction. Bang also right hand rule.
@baronvonbeandip
@baronvonbeandip 3 жыл бұрын
Too complex; got hand stuck in DNA strand.
@musashi939
@musashi939 3 жыл бұрын
@@baronvonbeandip that's Instructions unclear, got hand stuck in DNA Strand. Ftfy.
@Kerbezena
@Kerbezena 3 жыл бұрын
Thanks! Was about to comment the same. :-)
@OlegMilitaryHistory
@OlegMilitaryHistory 3 жыл бұрын
This comment needs to be way up
@heyitsbranigan
@heyitsbranigan 3 жыл бұрын
Thank you, Phineas & Ferb, for teaching us what an Aglet is
@mixmastermike2128
@mixmastermike2128 3 жыл бұрын
HOLY CARP!! WHAT AN AWESOME EPISODE!!!!!
@avp927
@avp927 3 жыл бұрын
MEGACARP!
@Qboi1982
@Qboi1982 3 жыл бұрын
Agreed
@grLoLaras
@grLoLaras 3 жыл бұрын
My whole life is a lie....
@myrinsk
@myrinsk 3 жыл бұрын
EXTRA CARP
@scarletspidernz
@scarletspidernz 3 жыл бұрын
MAGI KARP!!
@BothHands1
@BothHands1 3 жыл бұрын
ty for the advanced biochem!! i had to drop out last semester due to unforseen circumstances, but starting in january, i'll be going back and retaking the course. and this video def helped bring some excitement back to me for that class.
@lunanightingale3336
@lunanightingale3336 3 жыл бұрын
Same here. I got sick during my spring quarter and had to with drawl from all my classes. We'll make it through.
@BothHands1
@BothHands1 3 жыл бұрын
@@lunanightingale3336 ty, best of luck to you!!! we'll def make it through this time!!
@hamstsorkxxor
@hamstsorkxxor 3 жыл бұрын
Best of luck! If 2020 has proven anything, it is the importance of life-science!
@BothHands1
@BothHands1 3 жыл бұрын
@@hamstsorkxxor or it's taught us that we messed up the mayan calendar. it was supposed to be 2021, not 2012. i have my bets on a meteor sending us back to the stone age around january 1st.
@lunanightingale3336
@lunanightingale3336 3 жыл бұрын
@@hamstsorkxxor I'm tempted to study both CS and the life-sciences.
@Cornfedcryptid
@Cornfedcryptid 3 жыл бұрын
Props for giving Rosalind Franklin the credit she deserves and not solely crediting Watson and Crick with the discovery of DNA!
@Sakkura1
@Sakkura1 3 жыл бұрын
1:58 that's our haploid genome, but our cells are diploid in G1 phase and (sort of) tetraploid in G2 phase. So our cells have between 2 and 4 meters worth of DNA inside them.
@bwminich
@bwminich 3 жыл бұрын
A-G-L-E-T, don’t forget it!
@nguyendinh3338
@nguyendinh3338 3 жыл бұрын
Too bad only Candace remembered until SciShow brought it up again.
@michaeljames5936
@michaeljames5936 3 жыл бұрын
Those little doo-daws, which look like two aglets, held together by a short piece of string, for holding sheafs of paper together are.... 'Treasury Tags'. Please also bear that in mind.
@windhelmguard5295
@windhelmguard5295 3 жыл бұрын
the plastic tips, at the ends of shoelaces, are called aglets. their true purpose is sinister
@dankuchar6821
@dankuchar6821 3 жыл бұрын
I miss those two boys.
@ImplodedAtom
@ImplodedAtom 3 жыл бұрын
Hey, where's Perry?
@leogama3422
@leogama3422 3 жыл бұрын
Are you trying to melt my brain *again* Hank?!
@wonderwend1
@wonderwend1 3 жыл бұрын
He melts our hearts through our brains
@HN-kr1nf
@HN-kr1nf 3 жыл бұрын
so glad you guys mentioned rosalind franklin, no science lesson has ever mentioned her!
@robertomorales8751
@robertomorales8751 3 жыл бұрын
Ngl I did not think an aglet would be mentioned. Phineas and Ferb was an amazing show.
@EksaStelmere
@EksaStelmere 3 жыл бұрын
Gods, every time I hear "Rosalind Franklin" I'm reminded you can't win a Nobel Prize if you're dead.
@tim40gabby25
@tim40gabby25 3 жыл бұрын
Imagine you resurrect Rosalind and SHE gets the Nobel prize? :)
@EksaStelmere
@EksaStelmere 3 жыл бұрын
@@tim40gabby25 Nah, it'd just be that she gets the prize alongside Watson and Crick. that's how Nobel prizes work.
@ArianrhodTalon
@ArianrhodTalon 3 жыл бұрын
I appreciate that Sci-Show said 'based on data collected by Rosalind Franklin'
@Yalami8
@Yalami8 3 жыл бұрын
I thought I knew something about DNA before watching this video...
@davidanalyst671
@davidanalyst671 3 жыл бұрын
this wasnt a great video. He is terrible at explaining things.
@alphagt62
@alphagt62 3 жыл бұрын
I confess to knowing little about DNA, and have no idea how the information contained within communicates with the rest of the cell?
@Kiemixo
@Kiemixo 3 жыл бұрын
Lol
@albertjackinson
@albertjackinson 3 жыл бұрын
Now THIS is what should be taught in high school Biology about DNA! It's a great expansion on what I learned last year, too.
@ProfAwesomeO
@ProfAwesomeO 3 жыл бұрын
Today I learned geneticists suck at the alphabet
@massimookissed1023
@massimookissed1023 3 жыл бұрын
So do astrophysicists. Stars are classified into the following groups: O B A F G K M
@semaj_5022
@semaj_5022 3 жыл бұрын
@@massimookissed1023 astrophysicists suck at number order too. The very first, oldest stars are population 3, then medium age are pop 2 stars, then the youngest stars are population 1... I don't even know what they'll deign to call the next population. 0? .5?
@jaschabull2365
@jaschabull2365 3 жыл бұрын
And don't get me started on the scientists who name vitamins...
@alexgulino335
@alexgulino335 3 жыл бұрын
@@semaj_5022 hmm... well if they gave them number age at the same time it makes perfect sense in that they were the 'first age of stars the 'second age' and so on, but if they didn't then they happened to guess a great number to start on and we happen to live in the goldilocks zone of time before they're proven wrong lol.
@suelane3628
@suelane3628 3 жыл бұрын
Not to mention chromosome numbers. They should be in order of size with 1 being the biggest: but our chromosome 21 is smaller than 22. To be fair, it looks like a difficult job to measure them in the past.
@brandonkelley6500
@brandonkelley6500 3 жыл бұрын
I took a genetics class over the summer and I still learned a lot from this video
@Clockworkcityofpain
@Clockworkcityofpain 3 жыл бұрын
THIS IS ALL HAPPENING INSIDE OF EVERY SINGLE ONE OF OUR CELLS I AM HAVING A PANIC ATTACK. THANK GOD I'M NOT A MOLECULAR BIOLOGIST
@funnyyylock
@funnyyylock 3 жыл бұрын
Riight
@massimookissed1023
@massimookissed1023 3 жыл бұрын
This is also going on in cells: kzfaq.info/get/bejne/eMWqd5Z_3bnXdGw.html There are transporter molecules that actually walk along scaffolds.
@davidanalyst671
@davidanalyst671 3 жыл бұрын
Every cell knows its time is limited, so it copies its dna to make a new cell before it dies. They copy very very fast. The brain of every cell is a copy machine duplicating the DNA. The exciting part is that humanity doesn't have a stinkin clue what any of it is. Have you ever wondered why dogs can eat raw meat and we can't without catching Ecoli? Have you ever wondered how Rona takes over our bodies, and we can't do anything but the usual to stop it? Have you ever wanted to grow a labrador retrievers head on your hip so you have a permanent emotional support animal? All this is controlled by DNA, and humanity doesn't know 1% of how DNA works
@dimitraBlissDk
@dimitraBlissDk 3 жыл бұрын
I have a double whammy 2 forms of EDS. I have a complete duplication of one gene and point mutations in 2 other genes related to collagen. I had to retire early from being a pharmacist. It was like my life ended. I love science and in college I TAed a cancer biology class. That was early 80s. My kids have told me they think I would have been happier in research. I think they are right. I love your videos. You must have access to all the publications behind pay walls. So thanks for sharing and helping me to keep learning.
@bradywells1293
@bradywells1293 3 жыл бұрын
sci-hub.now.sh/ (google "sci-hub.tw" for alternate mirrors if it's down). It'll grant you access to almost any science publication behind a paywall for free. You could alternatively email corresponding authors on papers and just ask for a .pdf and 9/10 times they'll send it to you. Most researchers aren't crazy about limiting knowledge that big journals do and will happily help out anyone interested in their work, regardless of background.
@dimitraBlissDk
@dimitraBlissDk 3 жыл бұрын
Thanks
@lolo8698
@lolo8698 3 жыл бұрын
Very cool Hank, thank you
@saenes6295
@saenes6295 3 жыл бұрын
This video is like a continuation of my genetics class! haha
@SegmentW
@SegmentW 3 жыл бұрын
I love the intro so much and Hank is my favorite amalgamation of DNA
@SwordQuake2
@SwordQuake2 3 жыл бұрын
6:15 that's Isu DNA.
@AshleyRajam
@AshleyRajam 3 жыл бұрын
Annunaki confirmed
@thomasfholland
@thomasfholland 3 жыл бұрын
So explains why my gene 22 had a piece of it break off and when my gene 9 had the same thing happen and those 2 broken pieces switched places causing me to be diagnosed with a rare nasty form of leukemia: Philadelphia Chromosome positive acute lymphoblastic leukemia (Ph+ALL) I can highly recommend that you never have to deal with this type of cancer. It was literally hell on earth for 3 years!
@andreearoman7001
@andreearoman7001 Ай бұрын
hey, my bf has the same disease, he was diagnosed 10 years ago , and since then he changed like 3 types of pills , are u on pills too or you did the transplant?
@johanneshalberstadt3663
@johanneshalberstadt3663 3 жыл бұрын
"From lower left to upper right" says nothing if you don't specify if clockwise or anticlockwise. Or in other words:"coming around the front or the back".
@Starfals
@Starfals 3 жыл бұрын
This was very informational, love the video :) I swear, i have learned soooooo much from this channel (about many topics) that its just unreal.
@jehmarxx
@jehmarxx 3 жыл бұрын
Three kinds of people this time: 1. People who don't know there are different kinds of DNA clicking on this video. 2. People who already know the different kinds of DNA but still click this video. 3. People who can't figure out the difference of left-handed and right-handed DNA.
@lllllllllll1164
@lllllllllll1164 2 жыл бұрын
4. People who believe dna is just some random fibres sent by God in body
@semaj_5022
@semaj_5022 3 жыл бұрын
This was incredibly interesting. I love episodes like this. Keep up the amazing work, SciShow!
@TaylorFalk21
@TaylorFalk21 3 жыл бұрын
I was just thinking about this the other day, and was going to try to search for videos on here about it....then... BOOP! A video about it on my watch list
@naturallyadapted2096
@naturallyadapted2096 3 жыл бұрын
Gotta love having literally worked in genomics for several years and still being able to take away information from videos like this. Good refresher, but I had no idea about G-quadruplexes
@wolfy8006
@wolfy8006 3 жыл бұрын
Thank you, for reminding me of Lehinger Principle of Biochemintry. I will go and cry now.
@pamelapilling6996
@pamelapilling6996 3 жыл бұрын
Learned so much. Thanks Hank and the Complexly crew.
@lindakay9552
@lindakay9552 3 жыл бұрын
I'm glad to see that you're still releasing new content Hank! Keep it up!
@caiohenrique1603
@caiohenrique1603 3 жыл бұрын
yeah, the last track he dropped was fire 🔥
@willinwoods
@willinwoods 3 жыл бұрын
Hank is the used car salesman of DNA. "You won't believe the number of strands you can pack into this beauty..." *pats on roof*
@hellothere7961
@hellothere7961 3 жыл бұрын
Cool Connection: A few days back, I remember reading in the news about Israeli scientists reversing aging by somehow preventing the telomeres of chromosomes from deteriorating. Really nice coincidence that Hank mentioned telomere stuff in this video as well (at around 7:45), it's really got me wondering. Great video!
@sagacious03
@sagacious03 3 жыл бұрын
Decent analysis of this video! Thanks for uploading!
@angus8353
@angus8353 3 жыл бұрын
This video would have made my Biochemistry study in university SO much easier and more enjoyable to learn! I found it to be some of the most dry and tedious content in the whole degree but you guys always find a way to make complex information so digestible.
@MrMikkyn
@MrMikkyn Жыл бұрын
Its so fascinating how the same information can be made easier to learn if the teaching is engaging. It makes me wonder why a dry teacher and a fun teacher teaching the same thing can have a completely different effect on the knowledge acquisition of a student.
@gerrie2477
@gerrie2477 3 жыл бұрын
SO much information in 10 mins, . and at that, BARELY scratching the surface of what we know, forget about what's still to learn, . always exceptional videos. :o)
@germanarellanocampos5119
@germanarellanocampos5119 3 жыл бұрын
Great video. That is why my kids and I love your channel.
@SkyraHope
@SkyraHope 3 жыл бұрын
Great video! I love watching all of you! You really bring fun into science! Thank you!♥️👍
@alien9279
@alien9279 3 жыл бұрын
*Has DNA image in intro* Like how you guys have showed that atoms, and DNA, are both different than the common representation. But also, both are still in the intro, which I like haha
@deborahhannah8275
@deborahhannah8275 3 жыл бұрын
I could listen to Hank Green talk forever, even when I don't have the slightest idea what the @#$&!? he's talking about.
@wonderwend1
@wonderwend1 3 жыл бұрын
Same
@davidanalyst671
@davidanalyst671 3 жыл бұрын
thats because he is terrible at explaining concepts like DNA
@elif6908
@elif6908 3 жыл бұрын
I honestly think KZfaq stopped showing your videos to every subscriber! What an abysmal subscriber to view and view to like ratio for an amazing video! Thank you SciShow for teaching me things I would never even be curious about and doing it in a such a accessible way.
@hunterc626
@hunterc626 3 жыл бұрын
I understood about 1% of this video, but I was absolutely blown away. Now I must play massive amounts of time on video games to numb my brain.
@abyssal_phoenix
@abyssal_phoenix 3 жыл бұрын
Triple strand dna gives me “zoo” vibes. That series, zoo. Where animal mutation caused animals to get aggressive and super strong and stuff
@alfredsutton7233
@alfredsutton7233 3 жыл бұрын
Good summary of our current understanding, Hank.
@MichaelHarrisIreland
@MichaelHarrisIreland 3 жыл бұрын
Thanks, amazing stuff.
@fredbach6039
@fredbach6039 3 жыл бұрын
Nice work, guys! I learned a ton. I figured there had to be something like this in order to unwind and read/copy/repair DNA, considering how the DNA is wrapped tightly around the histones. Just a comment - teaching science as history is a very good idea. I like the way you do it. More more please! A longer mention of the mechanics of epigenetics would be very helpful.
@rajendrakhanvilkar9362
@rajendrakhanvilkar9362 3 жыл бұрын
Always loved ur videos
@TheRogueWolf
@TheRogueWolf 3 жыл бұрын
"The plastic tips at the end of shoelaces are called aglets. Their true purpose is sinister."
@marcochimio
@marcochimio 3 жыл бұрын
Actually, it's just the left one that is sinister.
@davidanalyst671
@davidanalyst671 3 жыл бұрын
they always fall off at the most frustrating moment when you are trying to tie your shoe
@mbaxter22
@mbaxter22 3 жыл бұрын
Amazing how much we still don't know.
@scorpio6587
@scorpio6587 3 жыл бұрын
1:20 Yes, it does. You point your thumb in the direction of travel along the central axis, and your fingers show the direction of wrap around the axis. It works the same way way for electromagnetism.
@Fercurix
@Fercurix 3 жыл бұрын
WHen is 4K-DNA coming?
@arrachi1309
@arrachi1309 3 жыл бұрын
Coming soon to a theater near you
@the_sockdolager
@the_sockdolager 3 жыл бұрын
Thank you so much for giving Mrs. Franklin then credit she deserves.
@Sharkyktc001
@Sharkyktc001 3 жыл бұрын
I'm glad this was about shapes and didn't bring up histones too much. I did my masters degree on ONE very specific histone modification in ONE type of cell and even that was absurdly complex.
@supernova8962
@supernova8962 3 жыл бұрын
wow another great show
@MikeStoddart
@MikeStoddart 3 жыл бұрын
This is all way over my head!
@Neo2266.
@Neo2266. 3 жыл бұрын
G-Quadruplex sounds like what Muscle Hank calls his biceps
@harrietharlow9929
@harrietharlow9929 3 жыл бұрын
Thank you for posting this. Now I understand a bit better about DNA and how it works.
@rajendrakhanvilkar9362
@rajendrakhanvilkar9362 3 жыл бұрын
Great video
@ibadullahtahir7541
@ibadullahtahir7541 3 жыл бұрын
I love scishow. You are the best . and also hank green the scishow host
@Rabcup
@Rabcup 3 жыл бұрын
Thanks hank this intrigued me in biochem before I dropped the course
@BothHands1
@BothHands1 3 жыл бұрын
hell yeah!!! biochem is awesome!! unfortunately my professor barely speaks english, and his handwriting is virtually illegible, and he's the only upper division biochem teacher at my university. so his class was hard af, cuse i had to learn everything from a pirated textbook online. unfortunately my roommate/ best friend was arrested half way through the course b/c her bf was selling counterfeit rolexes or some stupid sht. so i couldn't pay rent and had to move into my dad's for a bit, and it didn't help that homeland security stormed my house at 6am with guns drawn in my face, so i was pretty traumatized. there was nothing in my house except a bit of pot, but they didn't care about that. then they questioned me until like noon, after searching the house, and i had a bit of a mental breakdown after that. so i had to drop my whole semester. but january i'm going back and vids like these make me really excited. i wanna finally finish school, especially since i'm living with my girlfriend right now, and i don't want her to see me sitting on my butt all day. so i'm super motivated to get back to the grind, and biochem comes first. plus i think one more elective in upper division neuroscience. i've already done a bunch of work towards my masters already though, so i'm not quite as set back as i feel. but i really can't wait to start being a human again. and it all starts with that biochem course. sorry if i vented too much lol i'm just stressed
@SuperibyP
@SuperibyP 3 жыл бұрын
Holliday junctions were the genuine bane of my cell biology and genetics modules. Beautiful and interesting, but a pain.
@inbasicterms-popculturevid1704
@inbasicterms-popculturevid1704 3 жыл бұрын
gnarly af
@little_forest
@little_forest 3 жыл бұрын
On an educational note: The topic of this video is not "what DNA looks like", but how DNA is structured. This was said in the summary, though I think one has to clarify the title. One cannot "see" the DNA or a molecule in general. We do make pictures of DNA, but those are only representations, but not "the real thing". For scientists, the most important thing about atoms and molecules is how they are structure when they make up matter. When scientists say "that is what molecule X looks like", it is just a simplified expression of "how molecule X is structured". No scientist actually thinks they can "see" or "look" at a molecule... I hope ;)
@chaser107
@chaser107 3 жыл бұрын
One of the best this has to be
@NKerr86
@NKerr86 3 жыл бұрын
Hank! My kids were so excited to see you on Tiktok!
@batya7
@batya7 3 жыл бұрын
Way cool stuff discovered since I was a bio major in the 70s!
@davewilson13
@davewilson13 3 жыл бұрын
You should have mentioned Wilkins with the A and B structures. He worked next to Franklin (though fraught with tension). He was also her supervisor though he seems never to have told her. Otherwise great video.
@saaustin9
@saaustin9 3 жыл бұрын
friggin awesome.
@personinthepiano
@personinthepiano 3 жыл бұрын
cant wait to study this
@DG-xg8vg
@DG-xg8vg 3 жыл бұрын
Going to show this to my students when I teach them intro to molecular biology next semester. Cheers±
@squeezemyparticiple
@squeezemyparticiple 3 жыл бұрын
Do you think figuring out how to prevent H-DNA (particularly on the c-myc gene) from forming might help prevent cancer, since it's one of the most prevalent genes associated with cancer?
@Matt_Legler
@Matt_Legler 3 жыл бұрын
Can your next video, related to this, be about cellular aging (cellular senescence and telomere shortening)? Really interesting stuff :D
@ellhullio26
@ellhullio26 3 жыл бұрын
Hey SciShow; I hoped you would explain the acronym of DNA. How does deoxyribonucleic acid mean what it does? Just the fact that it's an acid is hard to believe.
@rdizzy1
@rdizzy1 3 жыл бұрын
Many building blocks of life are nucleic acids. Complex carbs, lipids, and proteins as well. DNA may have an acidic PH, but the cell itself maintains a neutral ph, as it has other things that can level out the overall acidity.
@Sharkyktc001
@Sharkyktc001 3 жыл бұрын
'Deoxyribo-' refers to the sugar backbone of the DNA molecule, which is a sugar called deoxyribose. It is called deoxy- because it has 1 less O molecule than another sugar called ribose. 'Nucleic' refers to the nucleobases (the A, T, G, C parts of the molecule) and the reason it's acidic is because there is a phosphate group attached to the sugars, and it's these phosphate groups that help form very strong bonds along the backbone to hold the molecule together. Remember that an acid just means something that can lose a proton (a H atom). When its formed a bond between two DNA molecules, the phosphate group still has an -OH group that can easily lose that H at normal pH, so that makes it an acid. It's not what you'd usually imagine an acid to be like - there's no risk of melting someones face off if you spill some DNA on them!
@lllllllllll1164
@lllllllllll1164 2 жыл бұрын
People think acid is a chemical that produce salt with base.
@silvermist6891
@silvermist6891 3 жыл бұрын
Hank, you're always my favourite. Take love xxx
@vegahimsa3057
@vegahimsa3057 3 жыл бұрын
Right handed (metaphorically) has everything to do with hands. Your thumb points axially and the fingers show the direction of the curve or twist
@bunnygirl2448
@bunnygirl2448 3 жыл бұрын
Omg I have wondered what DNA actually looks like! I knew it didn’t actually look like the models. Thank you!! Thank you!
@soundwavepg3d254
@soundwavepg3d254 3 жыл бұрын
Scoliosis: hmm looks like im left handed
@0Saqia0
@0Saqia0 3 жыл бұрын
thank you x
@TheKocton
@TheKocton 3 жыл бұрын
Graet I will use this video to explain may Biochemistry students in school Medicine
@SWBF2-2005IsBestStfu
@SWBF2-2005IsBestStfu 3 жыл бұрын
7:45 A G L E T. Aglet, don't forget it
@yleeckles2289
@yleeckles2289 3 жыл бұрын
You should do a vid on what DNA tastes like, for Patreon supporters.
@Sharkyktc001
@Sharkyktc001 3 жыл бұрын
Its probably pretty tasty, disodium 5′-ribonucleotides are a food additive used as a flavour enhancer for extra umami
@michaeljames5936
@michaeljames5936 3 жыл бұрын
Ok TLDR: DNA can rotate one way, or the other, depending on whether you are right, or left handed. Sometimes you have a triple strand or 'H' DNA, this stands for 'Handy' and is what ambidextrous people have. There are ten bases in a complete turn, which is why we have ten fingers. Got it correct, right? (little pun there.)
@newbyclive
@newbyclive 3 жыл бұрын
I, a time traveler, is still waiting for the scientist to discover Agelets
@GroovyGrov
@GroovyGrov 3 жыл бұрын
My favorite classes were molecular biology and genetics. Thanks !
@HN-kr1nf
@HN-kr1nf 3 жыл бұрын
god i love this channel
@tsites1
@tsites1 3 жыл бұрын
Actually right handed does have to do with hands. When you put your right hand out with your thumb pointing up your fingers curl in the direction of the right handed helix. Right handed rules are everywhere in science and engineering. For all right handed screws (including light bulbs and other threaded objects) if you turn the screw in the direction of the curl of your fingers, the screw (or whatever the threaded object) will move in the direction of your thumb. In physics, you can use the right hand rule to determine the direction of a magnetic field around a wire when your thumb is pointing in the direction of the current. There is much, much more.
@Nordbish
@Nordbish 3 жыл бұрын
Would be awesome if you would do a video on the OMAD diet and or intermittent fasting in general.
@StrunDoNhor
@StrunDoNhor 3 жыл бұрын
Out of curiosity, is there a way of explaining how these processes work _without_ personifying them? If it's because we genuinely do not know how they're done, then that's fine, but I personally find that hearing polymerases "check their work" by "proof-reading" with A-DNA is far less helpful (and far less interesting) than just explaining the actual chemical process.
@fromthefuture7172
@fromthefuture7172 3 жыл бұрын
If all teachers started with what's actually going on then we'd have no scientists today.
@kojdify
@kojdify 3 жыл бұрын
I had a test on this on saturday... This sure would have helped
@sleepymari8915
@sleepymari8915 3 жыл бұрын
im in my third year of a genetics degree. i have been summoned.
@silentcaay
@silentcaay 3 жыл бұрын
6:50 - Oh, so this is the strand that broke the DNA's back.
@liggerstuxin1
@liggerstuxin1 3 жыл бұрын
2:12 I remember hearing that all of our DNA would stretch (according to Google 2 meters long per cell) across the solar system twice; I used to always think that it was one strand of DNA that would stretch that far, not the combined DNA from every particular cell. Good to know.
@twocvbloke
@twocvbloke 3 жыл бұрын
I dunno, it all seems like a long and twisted tale to me... :P
@shaunmcinnis566
@shaunmcinnis566 4 ай бұрын
I'd like to see more information on "how much information," is in a strand. I thought I read there was 50 million base pairs? If so, this is mind blowing. I'd love to know more.
@dallasoch
@dallasoch 3 жыл бұрын
How are there 14 comments already when it says video just posted 14 mins ago! People are on it!
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