This video explains microsatellite instability (MSI), an important test in cancer. Learn which cancers require MSI testing, such as cancers of the large intestine (colon and rectum), small intestine, stomach, gallbladder, liver, and uterus. Learn the modern techniques used to test for MSI. Immunohistochemistry (IHC), PCR, and NGS can be used to test the cancer DNA quickly and cheaply.
Immunotherapy plays a special role in MSI cancers. We discuss the role of MSI and mismatch repair (MMR) in the treatment of stage 4 cancer. Learn how MSI is important in choosing effective treatments, including chemotherapy, targeted therapy, and immunotherapy. Understand how immunotherapy, which includes drugs such as pembrolizumab (Keytruda), atezolizumab (Tecentriq), nivolumab (Opdyta), ipilimumab (Yervoy), and dostarlimab (Jemperli), can improve long-term survival in patients with MSI cancer and can even cause cancer remission in many patients. Learn from Delhi's renowned Cancer Specialist Medical Oncologist Dr. Vineet Govinda Gupta MBBS (AIIMS) , MD (AIIMS), DM (AIIMS), Gold Medalist.
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Phone: +919013812875, +917290928042
Website: drvineetgovinda.com
E-Mail: vineetgovindagupta@gmail.com
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00:00 Introduction परिचय
01:10 What is microsatellite instability माइक्रोसेटेलाइट अस्थिरता क्या होती है
02:30 Importance of testing for MSI यह MSI जांच कराना क्यों ज़रूरी है
05:41 Cancer types where MSI is common कौनसे कैंसर में MSI पाया जाता है
07:02 Testing for MSI टेस्ट जिनसे MSI पता किया जाता है
10:07 Treatment of MSI positive cancer MSI वाले कैंसर का इलाज कैसे करते है
15:13 Contact information संपर्क