That was a personal attack at Bill. We stan in solidarity with Bill :')

as an Infectious Disease Fellow, we basically spend all day fixing all the other doctors’ antibiotic mistakes. We take it personally.

Rip Bill dude. But you know what? That 2 hour warning is worth every penny. This man now has time to properly prepare: toilet paper, comfortable toilet, comfort materials like headphones, speakers, a fully charged phone, a phone charger (long haul case), a healthy amount of water and crackers, and a disproportionately comfortable living space. Prepare for the worse Bill. The next 24-72 hours are gonna suck my guy. 😂😂😂

The pan-resistant pseudomonas made me gasp out loud. Found one last year. My boss was super excited, we now show it to every new doc who'll listen long enough as a cautionary tale. That and the Gonorrhoea we somehow managed to culture and keep alive for half a year now. Also RIP Bill, next time ask someone from the lab for food, we always have a (still sealed) granola bar for you. We can even warm it up in the incubator if you ask nicely :)

Whenever you put out a new video, I always think to myself: he's set an impossible standard for himself, yet here we are again... exceeding expectations. Brilliant.

When he asked "What is your greatest fear?", I thought he'd answer: "Character limits in free text fields"

This is like a trip down memory lane through microbiology. Also, the “pan-resistant to change” killed me. This and the neurosurgery ones are my favorites yet

Platinum, wrapped in gold, with caviar on top, with a side of satire.

Last year mom in law had MRSA septicemia and the ER doctor initially gave her Ceftriazone. After the consult, the ID doctor quickly changed her antibiotics and found out that the cause of her infection was her ingrown toenail. I was so amazed!! ID med are like the Sherlock Holmes of medicine. 👏🏻👏🏻👏🏻

As a molecular biologist, I felt every bit of the fear of antibiotic resistance and frustration at antibiotic misuse. Bonus fact: Most antibiotic resistance is found in plasmids, and not as part of bacteria's central chromosome (They do sometimes incorporate, but then also transpose back into plasmids). Given that such plasmids tend to have a fairly short generational half-life, if we could get every country on board, we could take select antibiotics completely out of circulation for a number of years. Those resistance plasmids would all but disappear in that time, allowing us to bring back those antibiotics into use at much greater efficacy and then take another set of antibiotics out of circulation, and repeat this cycle to keep our existing antibiotics viable for potentially decades or centuries.

as a Jonathan to clinical pharmacist-ICU consultant this hits too close to home. Pan- resistants are true fear. I just finished making report on 6 months antibiotic usage on those nasty pan-resistants and so many inappropriate/too late prescription. The biggest heartbreak was all these babies passed away without fighting chance 😭

Yes! Please shame doctors for poor antibiotic choices and prescription errors. Like that time I found that a patient had been prescribed amoxycillin continuously for over six months, two weeks at a time, for some kind of foot ulcer by a succession of different doctors in the outpatient department who probably hadn't felt the need to check the patient history. Though self-prescribing patients are equally to blame, the number of times a patient has come to the pharmacy requesting 'just one amoxycillin capsule' for a sore throat, I swear... When infections become resistant to the last resort antibiotics, I'm telling the whole world I told you so. Sincerely, An exasperated pharmacist.

Feeling seen, crop scientist here who started out in pest management (dealing w pesticide-resistant insects & fungal diseases) & moved on to food safety (RIP Bill). This whole series is A+ but am feeling this one on a deep level. :_)

"pan-resistant to change" love it! And poor Bill.

We finally discovered doctor bills real problem… He’s participating in every single fellowship at once.

One of my worst experiences: doing a PR exam (DRE) on a patient with diarrhea, and infectious disease call seconds later to say he's C. difficile positive 😭 probably because of the antibiotics we'd given him 😭😭😭 (I took a looong shower that day)

Yay! Finally an infectious disease one! I’m still in med school but I’ve already started prepping for fellowship by writing prose-like SOAP notes and roasting doctors giving out antibiotics inappropriately. A friend of my got doxy for his asthma and I was like ??? tf kinda doctor would give you DOXYCYCLINE for asthma and allergies??

🤣🤣🤣 oh no Bill!! Everyone knows to only eat the *untouched* food left on the tray; not the half eaten stuff! Bill must have been *REALLY* hungry hahaha

As a nurse I love this channel, the stereotypes are so true. I love especially that this is the one specialty that he makes looks incredibly competent and noble. Its fun to make fun of so many of the other specialties but I like that he has given credit where it is due to these docs.

Chapter 3 of his personal statement had me rolling

THE TEAR.

Throwback to 6 years ago when I caught something during the flu season and kept going back to the doctors because I was getting worse and got everything from a cold to flu, to bronchitis, to walking pneumonia as my diagnosis. Never did find out what the hell I had because the docs kept changing their minds and didn’t bother running the more extensive labs and cultures for whatever reason. 🤷‍♀️ My manager from at the time still forced me to come to work regardless of the diagnosis, which… I sure hope isn’t something he’s still doing. 🙃

Yes!!! Wicked funny! I did have to look up A LOT of the terms in this video which only made it funnier!

It's very funny but at the same time very alarming even for us biologists that doctors are ordering antibiotics like sweets, causing more and more resistant strains to emerge. Keep entertaining us doc

As a student studying antibiotic resistance, I loled extra and loved this so much. Thanks for adding a laugh to our days!

Get Bill an IV and start fluids. He’s going to need them. Poor Bill

Hey Doctor! I loved your infectious disease clip so much!!! I'm a veterinarian, and very oft I battle infectious diseases by animals, always in regard to safekeeping the health of humans. Infections are really sometime a big challenge. Keep up the good work! (Sometimes it feels like the world has forgotten us veterinarians)

I once also was a MRSA patient that received penicillin. It took only a day until it got so serious that the doctor wanted to put me into hospital. Luckily the broad spectrum antibiotics I received did their job until the lab results were back and I got the correct antibiotic. Still, having a highly infectious disease while backpacking in Australia meant that for 4 weeks I had to move out of the hostel to a tent and wash my clothes and bedding daily, as well as desinfecting everything I touched more or less. Plus I also had to learn how to dress my own bandages which wasn't easy because I had open wounds all over. The wounds were from skin cuts from work or mosquito bites that I scratched open, every cut in my skin was leaking golden yellow pus for nearly 2 weeks. It didn't make me want to become an infectious disease doctor but it did raise my awareness for antibiotic resistant bacteria more than any news report ever could.

[waves] Infectious disease epidemiologist here. The medicine vs. public health mentality is real. We're all dreading the day that pan-resistant bacteria emerge, but at least we'll get to tell the doctors we told them so.

Poor Bill!! Hugs from your fans here in Argentina ♥️

You are my favorite internet comedian! As a CRNA having gone to Anesthesia school at Baylor, I saw all of your memes played out over the years. You are spot on!! Thanks for all the laughs🤣

I just took microbiology for pre-nursing and I feel so proud that I understood all of this :')

I am a clinical psychologist appointed to work with around 800 undergrad medical students and 300 specialising doctors and Dr Glaucomflecken is my and many of my patients' happy place. PS ...I felt seen with your sketch on luring doctors to the yoga session.

Glad I'm not the only one who recognizes the insane quality here! Fantastic job Doc 👏

You, sir, are a treasure to us all. Bravo 👏

I understand literally zero of the things you said and still found it hilarious. Love this channel ❤️

"shaming doctors for their antibiotic choices is one of the CORE competences of our fellowship program" Your accuracy and conciseness is unbelievable!!! Once one of my pregnant patients were criticaly ill and it was very likley that she would lose the baby within two days. But I was suggested to get blood cultures and wait for the antibiogram and to stop any antibiotic therapy till then which takes usually 2 to 5 days. Well, he had the bic picture of antibiotic resistency and I the small picture of this woman and her too small baby. Who is to blame?

That’s ok Bill; every customer of Taco Bell has been there. We stand with you!

The more I see you the more fascinated I become by you. Your depth of knowledge combined with present them with humour does not make you an extraordinary doctor, or comedian or anything else. You are an international asset for a very long time and I pray for you always for a long healthy life ❤️

Every second is a joke and would be a fine end to any video but it doesn't stop and just keeps coming with the jokes!! You're a comedic genius!

I have never felt this bad for a character

Bill needs a redemption arc. This is gut-wrenching.

As someone investigating antibiotic use in hospital settings I thank you for bringing attention to how we are pan resistant to change😂

I respect Bill's resilience

As much as I love pathology, infectious disease for the win! Hahaha but on another note, no bill doesn't deserve the E.coli!

Poor Bill 😂 Also, "we're the ones resistant to change," hits way too hard right now 😫

The subtle "chapter 3" reference on his personal statement hinting at how long ID notes are... genius.

You know doc, you sure know a lot of body medicine words for an ophthalmologist

I was till now able to resist eating patients left over food although I was tempted many times. Therefore I assume that the work conditions might be better over here in my hospital (in Germany). My colleagues and I were able to introduce shift times not longer than 13 hours 18 years ago - in our department of OG. And: the director of the hospital was very eager to implement that!!!! He is a good human. All the people in our hospital are lucky.

That was well done. ... Possibly unlike the chicken in Bill's scavenged sandwich.💩

I had MRSA in a surgical wound last century; I recovered by doing all my own wound care, because it quickly became apparent that scientists have much better aseptic technique than the medicos who were treating me (Exhibit A: the surgeon who didn't like to wash his hands between patients, because it dried out his skin and wasted his time). I can keep keratinocytes alive in culture without antibiotics, so dressings changes were a doddle. Lots of irrigation, lots of povidone iodine, and lots of sunlight. Exhibit A wanted to write me up in a journal article; sure I said, so long as I get authorship and final approval of the manuscript because I devised the treatment regime. Oh no, he said, you're a PATIENT. Well then, far cough, I said, and no, you can't have the pictures of the wound closing, no matter how much you cry. Poor ortho bro, he was so annoyed I bet he had to go and kick a kettle bell after that. Pan-resistant TB is what keeps me awake at night. It's rampant in PNG, and the islands that are just a short ride in a small tin boat north of Australia. And it responds to NOTHING. And I don't understand why more people aren't terrified.

Brilliant! They just keep getting better & better.

"personal statement" "In chapter 3" Amazing comedic skill

Watching these videos are what I do with my free time in PA school. Fingers crossed to work with an awesome doctor & mentor like Dr. G!

Funny as always. Always happy to see you post something new!

I’m having actual flashbacks to “Superbugs” by Matt McCarthy, but as he points out, antibiotic stewardship is more about picking /appropriate/ antibiotics (not limiting them) and all antibiotics probably already have natural resistance at some level. Anyway… great video! I loved it.

"We're pan-resistant to change" is an amazing line

I live in Northern Florida in the USA. I went to the ER for pneumonia, I caught necrotizing fasciitis on my right leg from an improperly cleaned emergency room gurney railing, and the infectious disease doctor misdiagnosed me initially. (Necrotizing fasciitis was "epidemic" where I live when this happened. I am told it was due to people swimming in several infected water run off ponds.) Rather than changing his diagnosis he insisted he was right, and after 8 days the Doctor who oversaw my case had me smuggled out to another hospital at 2am. When I got to the other hospital, the staff there took one look at my leg and said, "She's got necrotizing fasciitis. Schedule her for surgery." I owe that Doctor who arranged for my transport to another hospital at 2am my life. The Infectious disease doctor had told a loved one that he thought he should "take me off the antibiotics and let's see what happens" and she spoke to the Doctor overseeing my case, which is probably why he acted when he did. What would have happened was that I would have died. That infectious disease doctor no longer works at that hospital, btw. Anyway, the surgeon removed all of the fascia and some of the muscle bed from my leg from the knee down, replaced the lost muscle with corpse muscle, and took skin from my shoulders for a skin graft. They did a great job. I'm alive and I can move my leg and my foot! However, I have been trying to heal this leg for over FOUR YEARS NOW! I caught pseudomonas - probably from a home care nurse because it showed the first signs the day after her first visit and by the time she had been here three times (over a week's period) my leg was horribly infected. (No one touches my leg, which is completely bandaged in multiple layers of various items and covered at all times with a clean disposable chuck, except for doctors and nurses.) Apparently I wasn't the only one, because she was fired shortly after my wound care doctor contacted the home health company. They keep putting me on antibiotics and sometimes it seems to clear up mostly, and then the prescription runs out and It keeps coming back. (drainage the color of a pool table - green with a bit of blue to it.) Any suggestions on what to say to the Doctor to get them to keep me on antibiotics long enough to get rid of ALL of the infection? Or do I have this pan-resistant pseudomonas that they talk about in this video?

I absolutley enjoy watching these videos. Truly makes me laugh and feel good! Thank you for posting.

Ohhhhhhhh!!!!Hitting them with the sweet smell of grapes of the pan resistant aruginosa is definitely getting you in the infectious disease posse

OMG Bill! Won’t somebody please help this man?! Please let’s get together and save Bill!🥺

I actually thought Bill was going to be desperate enough to just start eating mustard satches

These skits seriously help me after a long shift, thank you!

This one of your best videos to date, well done man

Poor Bill. I'd Door Dash him a sandwich but who has time to run down to the after hours ER entrance to get it for him 😭

🤦🏼‍♂️ Bill, Bill, Bill.... might I recommend Quilted Northern, extra strength. It's a small comfort, but, sometimes that's all we have. 😏

The pride on his face at the end... ❤️ I wish someone was as proud of me 🙈🥺

I think this one might be your best video, yet. Watched it a dozen times already, I think. Terrifying and hilarious at the same time.

I want to give Bill a hug, I am Bill at work coworkers will be like did you eat lunch today it’s 6 PM and you’ve been here since 7 AM and I’ll be like does chugging hot coffee and burning my mouth in the process count cuz if so, you bet!

MacConkey agar = a man of class. 😂

freakin love these shorts you make lol

Brilliant. Absolutely brilliant.

One of the best ones so far

As soon as they mentioned the mustard, i knew exactly where this was going. Incredible fucking continuity between skits. Also, painful and hilarious accuracy. That patient to staff e.coli infection is exactly why dietary stopped bringing up boiled eggs for the breakfast trays in my ER. That cheap, stolen protein was too tempting a threat to my broke, depression-addled residents.

“Food finds its way into his mouth” …… this will be my tombstone epitaph.

Brilliant, Doc!!

I demand more infectious disease related stuff!

I hate when my patients come to me for follow-up after some Doc-it-a-box has treated their skin boil with Keflex. "But it's worse? You don't say..."

Oh, Bravo again! Brilliant!

Incredible work doctor, I really appreciate all your contents

Having finished my infectious disease rotation I'm pretty sure using Leukocytosis , Fever , CRP , ESR in one sentence would give an infectious disease specialist a heart attack.

I literally just heard myself say “Poor Bill” out loud. I think I might need to put my phone down for a short while.

One of your best, bravo!

Burst out laughing 😂 - These segments are my favourite!

Super as always 😍😍

The fear of antibiotic resistance reminds me of my experience with a dermatology PA who kept trying to give me antibiotics during an eczema flare because “your skin looks red.” Ya know, because eczema and topical steroids don’t cause that. 🙄 I’ve had eczema since I was 2. I know the difference between a flare and an infection. The final straw was at the third recheck when I’d vastly improved but he said, “You know, it’s still looking a bit red, maybe we should do another round just to be safe…” I NOPED out of there and found a new doctor, who confirmed there was no infection and happily ordered the light therapy sessions I’d spent 6 months begging the idiot PA for. I like to think if I’d gone into medicine it would be ID. It’s so fascinating to me.

I told an infectious disease doctor that I put myself on a course of horse antibiotics (tmps) - just to see his reaction. Best I could describe it was - think of when your PC crashed and displayed that blue screen of death, and now imagine that instead of the PC it's a human face. Worth it.

I love Bill...is the face of a Bad day at work...always🤣

Loved it! Bye the way I'm visiting an ENT for the first time tomorrow. Have I missed your ENT sketch or is it in the making? Hoping to see it 😊.

Poor Bill 🥺

My daily three minutes of serotonin. Thank you for this.

This just might be the best one so far

As a patient who has had to do IV Vancomycin at home for 8 weeks while still working a fulltime job and having an external fixator on my right arm due to being given 2, YES TWO staph infections during surgery to fix my broken bones in my right arm this is great comedy! I've also dealt with my 2nd husband being on Vancomycin for 8 weeks for MRSA which ate a hole behind his right eye the size of a walnut according to the ENT doc who gave him the disease while using a new flexible scope between patients which he thought was disinfected enough. No it wasn't. He also got Pseudomonas Aureganoses from the ICU when in for aspirated double pneumonia. He finally passed 7 years later after the MRSA episode from COPD while smoking 3 packs a day and being on oxygen. You only get one body, take good care of yourself as enough weird stuff will happen anyway and the healthier you are, the better chance you have to survive. Modern medicine is AWESOME but get your vaccinations like me and stay boosted. I have 2 autoimmune diseases and your help in getting us to 90% Vaccinated in the USA is greatly appreciated and Many Blessings!!! Love this channel

My pediatrician, 40 years practicing, said “When I am at work, I eat my sandwich 🥪 from the plastic wrapping. I never touch the food. When traveling, especially on a cruise 🚢, my wife and I only eat hot dishes, no cold fruit, vegetables or desserts.” He believes mostly all viruses are transmitted hand to mouth, especially in a pediatric practice.

I love how they say the line of resistance to change and the guy for the interview was crying. I already knew Dr. G was a great actor but my lord, he is just too good!

You are a genius.

Are Johnathans allowed to provide quickly consumable nutrition to put into the break rooms? As a future Johnathan, I would like to prevent low-glucose and fluid levels for the organic members of staff by supplying Boost Meal Replacement drinks and/or Core Power protein drinks.

Poor Bill. 🤣🤣🤣🤣🤣🤣

I loved this one!! You are great 👍

Hilarious AND spot on!!! Thanks Doc!!!