I do not understand why you do not have millions of subscribers. Such high quality, valuable, health-promoting content! Sending love from Texas ❤
@mikechang6737Ай бұрын
Because sensationalism sells, especially on the internet. Theres a natural and sad tradeoff between quality and popularity.
@JJ-ls4ejАй бұрын
@@mikechang6737 sadly, so true
@hidden909Ай бұрын
I always knew I had a high susceptibility to heart disease, family history, high blood lipids, borderline high blood pressure and an A1C that was high normal. I tried several statins with terrible side effects, so I have been on a WFPB SOS free diet for many years. It helped my lipids, but they were always still above normal. I kept my bmi at 20, and exercise daily. But at 69 it caught up with me! 3 weeks ago I had a big heart attack, fortunately, I got to the hospital quickly and with a wonderful cardiologist I had 4 stents placed and removal of a large blood clot. I’m starting to feel better now, I can take slow walks, and do housework and cooking. I’m doing well on a new statin that doesn’t cause me pain, and Zetia, blood thinners and beta blockers. And I’m feeling pretty grateful to still be here. I’m embracing modern medicine and hope to get some more years ahead of me. I just want to say lifestyle for some of us won’t get us into old age. But it’s probably going to help me get back to a normal life again quickly. ❤️
@carlbernngl25 күн бұрын
How long did you stay on the WFP diet?
@hidden90925 күн бұрын
@@carlbernngl I was vegan for 10 years, but WFPB, SOS free for 7. I haven’t eaten red meat for 35 years, and was mostly on a low fat diet for 30 years ever since I read Dean Ornish’s work. I was also a nurse so I understood what my lipids and family history meant. I’m feeling pretty lucky to be here now. I’ve been able to find some statins that I can tolerate and now I’m on blood thinners and beta blockers. But I learned the hard way, that for some of us, diet alone isn’t a sure thing. But I still follow the WFPB SOS free diet too.
@scienceislove201418 күн бұрын
Yeah, how can people expect to undo a lifetime of damage within a few years? Plus, some of us are cursed with terrible genetics. CVD runs in my family. I'm vegan for ethical reasons, and I am not SOS-free; I don't eat processed stuff, and that's about it. I like vegetable oils (such as olive oil); they make me glow (weird, right?). I almost wrecked my liver with a terrible sedentary lifestyle. I went SOS-free for 4 weeks and walked for 1 hour a day, and things are back to normal. My SGPT went from 70 to 16 (I was shocked). But since I'm really young (18), I think I can change and be in better health than most who choose to change at a later stage in life..
@nicolaspirletАй бұрын
Hey Gil! Thank you for your content. I just wanted to give you a little tip coming from someone who’s a sound engineer and who consumes your content mostly on earphones or in the car. You might want to compress your voice a bit to reduce the dynamic range. Currently, there are some quiet parts and some dramatic spikes in volume when you speak louder. This makes it a bit challenging to listen to comfortably, as I have to keep the volume low to avoid the louder parts hurting my ears. A little compression can help balance out the volume levels, making your videos more enjoyable for listeners in varying environments. Thanks again for all the valuable information you provide!
@jayalexandertilleyАй бұрын
Love the suggestion. Nothing ruins wonderful info more than improperly functioning/flowing sound. In case Gil does not know how to easily and quickly fix this (as i wouldn't), are you able to instruct at all? I'm not making any assumptions on behalf of Gil, at all, but just in case Gil doesn't have the time or the immediate fix, is it something you can easily relay in a general way that could be applied to any setup? Thanks for sharing your audio skills.
@NutritionMadeSimpleАй бұрын
@@jayalexandertilley Gil doesn't know how!! :)
@Sarloos.Ай бұрын
@@NutritionMadeSimple Hey Gil. You can use the free program "Audacity" to do so (there may also be other quicker options depending on the editing software you're using). There are plenty of tutorials on KZfaq, but it can be difficult to apply if you're new to audio processing. I would be happy to assist if you are interested and need help. It's also possible the sound engineer has better suggestions :)
@nicolaspirletАй бұрын
@@NutritionMadeSimple my suggestion would be to install Logic Pro if you’re on mac or cubase if you’re on PC. Then get an audio guy to create you a template session with a good voice mix. All done with native compression and EQ plugins. Then, when you shoot a video, when you’re done recording your voice, just drop the audio file in the session and export in wav 24 bit 48.000 hz. You might want to ask the audio guy how to do this. Then, import the track in your video editing software. With a bit of practice, it could take you 1 minute to do it.
@LaughinLoneStarАй бұрын
@@NutritionMadeSimple Audacity is amazing and free
@jayalexandertilleyАй бұрын
Gil, you are a wonderful human. Your compassion and skills are so deeply appreciated! I'm glad you exist and have found your purpose. We are lucky to have you spreading ways to health.
@DammikaW48474Ай бұрын
Agree with every word you stated. Dr. Gil Carvalho is saving lives by explaining TRUTH about health and nutrition.
@timhanley4396Ай бұрын
I have a high calcium score, I found out from a X-ray of my hip that showed calcium in my arteries. Besides that’s in good health for a 67 year old man. I love your videos cause it grounds me and gives me HOPE
@CedroCronАй бұрын
This video really cleared it all up for me. I never fully understood how all the things fit together to better control my outcome because I have a ton of genetic risk and family history risk. Thank you Dr. Carvalho
@wood6454Ай бұрын
We're so lucky to get these valuable information from an actual doctor for free. Thank you so much Doctor.
@wiadromanАй бұрын
"A simple visual that ties everything together" - you are talking about the Dude's rug?
@devonguyette1226Ай бұрын
Gil Carvalho Abides
@jedinxf7Ай бұрын
that visual really tied the room together
@joelamonica4874Ай бұрын
This is the best explanation of this topic that I have come across. The emphasis on the many factors that contribute to heart disease is refreshing and enlightening. It's clear to me now that treatment is a very personal issue. There is probably not a one size fits all treatment for all people. Thanks for making this video.
@4124V4TA-SNPCA-xАй бұрын
He is always like this. No BS, to the point, started clearly and add simple as possible.
@4124V4TA-SNPCA-xАй бұрын
He also has other videos you may be interested about. cholesterol, ApoB, LDL size: kzfaq.info/get/bejne/admDeK6UyqiUkqs.htmlsi=iaFQLuEgullnN5fa kzfaq.info/get/bejne/Z552eZehvrLclZ8.htmlsi=4URZ0McDptZwIwps kzfaq.info/get/bejne/hLuEqd2mqdbMnZs.htmlsi=dagj2HH_Jnh2FaGd High LDL with high HDL kzfaq.info/get/bejne/jtphmahzmcm1oJc.htmlsi=NFmgpK20PuyCcsp2 Ratios kzfaq.info/get/bejne/Zsp8ra6otNjWaIU.htmlsi=UfGXJ3Cz7op_gZ0B Saturated fats, seed oils and cardiovascular threats kzfaq.info/get/bejne/o6h2mJSCxtrYcYk.htmlsi=oPsEUlBWulHHZ6kS Low carb diet in heart health kzfaq.info/get/bejne/i6yRoK2Z2byYkWQ.htmlsi=Yg4pvO5yRIsKumtp Coronary Calcium Score (CAC) kzfaq.info/get/bejne/nd55mLWGx67Fpas.htmlsi=gjtil7OUVlQ1DLS3 Seed oils again kzfaq.info/get/bejne/lbynd72Hx8zWe6M.htmlsi=vIrLbWwTVWFlEvhp Triglyceride levels kzfaq.info/get/bejne/Y6horMWCkrKWZmg.htmlsi=F8-RhSKZjkHtj4NK Nexlatol effect on CVD risk kzfaq.info/get/bejne/a59niaqBtrmRm6M.htmlsi=FlpIEUhysNSdq4sS Plaque forming in arteries vs veins kzfaq.info/get/bejne/Zttgfpxo2d-cqKc.htmlsi=ejBPk0gJnHoeQ-Qo Canola oil specifically kzfaq.info/get/bejne/g56krcSJtq6Vd2g.htmlsi=UnGm1PrynJ8OtUKo Cholesterol kzfaq.info/get/bejne/m955g5V_ya2wo6s.htmlsi=FDb3bVtXtDhWq1HT Relation of IR with heart disease kzfaq.info/get/bejne/psmgkth81JPbp4E.htmlsi=TNvOLX0EnS485rf_ Causes of heart disease kzfaq.info/get/bejne/f92qgdGGzde5qpc.htmlsi=czcnMIxE6VGd-4N1 Exercise to reduce plaques kzfaq.info/get/bejne/q8lzfLZhqd68f5s.htmlsi=i7m-kkGg_U4cxi22 LDL size & heart disease kzfaq.info/get/bejne/odacm5Zht9O9n2w.htmlsi=MRfnrHhnyVhxxZHq The French Paradox kzfaq.info/get/bejne/qr56a8igmLaUhmw.htmlsi=5XiOdKN9hh2rq99Q Since how long heart disease plagues humanity kzfaq.info/get/bejne/e8-hjNCTv6-mdY0.htmlsi=0pgLVD39_P2u3-6E High Protein diet effects on heart disease kzfaq.info/get/bejne/Z7Wei7130bbRYJs.htmlsi=eXy82ORNpkmzxpu7 Oils vs. nuts kzfaq.info/get/bejne/qNyRqqins7LGhYE.htmlsi=eIJKwCkv_Ggl--wZ TMAO kzfaq.info/get/bejne/odF1ZpR4yJaah2g.htmlsi=yNz2wod3t4m3jafS Fish oil kzfaq.info/get/bejne/huClodx00ZrRn3U.htmlsi=Ifqac_CszRqlRrPT And this one. Since of these are in depth interviews with some of the best experts on their respective fields!
@f1nemanАй бұрын
Love this - clear with great analogies...with one tiny exception - bullets of course don't contain gunpowder... they are lumps of metal launched using gunpowder. The cholesterol is the metal inside the bullet. Some bullets are big and heavy, some smaller and lighter (some may contain more complex structures inside the jacket etc) - but I'll be sharing the video as overall it is excellent and everyone could learn a lot from it.
@jonbarlow3542Ай бұрын
Thanks Gil, for your simple interpretation, listening to you was time well invested!
@dietitianrobert5460Ай бұрын
Thanks Gil. I'll be using this analogy with my diabetes groups. Love a good analogy!
@apriljohnson6191Ай бұрын
Love the analogy. This one of your best videos.
@lynneward8845Ай бұрын
I love this video! It is such a clear explanation of the basics of atherosclerosis, it is like the clouds have finally parted! I now "get" the importance of ApoB, yay! Thanks so much, Gil. As a layman who is interested in nutrition and disease prevention, I find your videos incredibly helpful. Thank you, thank you!!
@captainbuck5969Ай бұрын
Another great, informative and educational video. This good doctor rocks!!
@mrmacguffin6886Ай бұрын
Great video! Very helpful, especially for those who are just entering the field of health self-improvement.
@user-ey8jz1zr2bАй бұрын
I’ve been watching your videos over the last few years and just want to let you know how useful I find your content. It’s very difficult to find diet information (besides reading articles from the top university journals). Whenever I get confused or feel like I’ve forgotten key aspects that make up a healthy lifestyle, I always come back to your channel to re-educate myself.
@arnodebrabant1396Ай бұрын
Another banger. What a treasure! Thanks Dr 🙏
@neilroberts4714Ай бұрын
I can only add my thumbs up 👍 to the others. Excellent video
@ramachandran8666Ай бұрын
Excellent review and useful summary of what to expect as well as anything one can do to lower the risks of CVD's. Your contents are always very fact-based as well as insight drawn from well researched sources
@AndrewPawley11Ай бұрын
Excellent information. Also ... go WFPB people.
@nx2120Ай бұрын
Whoop whoop. Went WFPB 2 months ago, cholesterol down, weight down, allergies gone, feeling good! Plus, it's good for the animals ❤
@ApoBeefАй бұрын
Sure, if you want to trade ASCVD for sarcopenia
@grego4835Ай бұрын
😅 yeah resistance training would be a big must. I prefer a whole food omnivorous diet myself@@ApoBeef
@kentroskelley1389Ай бұрын
@@ApoBeefkeep believing what you want to believe it may help.
@CncBladesАй бұрын
@@ApoBeefwould you rather have sarcopenia or heart disease?and people that don’t know how to gain or lose weight properly,get it.also,people that don’t have a weight training program do too
@peggykey5570Ай бұрын
You explain everything so well. Thank you!
@FitDadMD3 күн бұрын
We can’t control our genetics, but we should still be conscious of if we are at higher risk of certain diseases because of our genetics so that we can ensure we are doing everything possible to reduce our risk.
@kentroskelley1389Ай бұрын
Great analogy presentation. Thank you Dr Gil glad you’re out there clarifying all the noise!!!
@joanhall3718Ай бұрын
I loved this simplification of a very complex problem. Normally I am drawn to your videos because of your focus on scientific studies and analysis of same. This was a departure, but so good at synthesizing complex ideas.
@AksafanАй бұрын
This is the best health related vid I have ever seen 🔥🔥🔥🔥 Doc Gil is just a pro explanator of difficult things in simple words. Moreover, that is scientific based ❤❤
@StarchfaceАй бұрын
Hi Doctor Carvalho! I want you to know how much I appreciate the evidence-based approach you take to your videos. In a world where others shout their pet theories and diets from the rooftops, a voice like yours is sorely needed. Your channel is the home of sober second thought, the Senate of KZfaq. It's not that there's nothing to what these others say. Much or most of it is supported by evidence, but they will casually mention that high cholesterol is good without attribution, for example. They say the best lie is hidden between two truths. I'm not necessarily suggesting that these others are malicious, but we need to be cautious about applying things we hear from the internet to our own lives. In this you are very helpful. Your channel is severely underrated by my way of thinking, but thanks for doing all this. Cheers from Canuckistan!
@marshcreek4355Ай бұрын
An exceptional video that has made a lot things clearer for me. As usual great content that's enlightening and easy to understand. Love the unifying concepts of bullets vs barrier and the interplay between the two. Given that I'm someone who didn't win the genetic lottery this has put me at ease in managing my risk. At age 74 arterialscherosis is now real in my life. One can only work on the best strategies to mitigate it and do the best you can.
@Lumencraft-27 күн бұрын
That was very well laid out and easy to understand. Packed full of great information. I like the bullets and barrier analogy.
@saganspiritАй бұрын
Probably the best analogies I've ever heard on the subject - great stuff
@PhilippeOrlandoАй бұрын
Great, I'm always after all kind of unifying theories!
@jenniferhutson8579Ай бұрын
Would love a discussion re gender differences. Isn’t the efficacy of statins quite a bit lower for women, and, if yes, then why? The menopause transition dramatically raises LDL, thereby creating dyslipidemia. Does the increased need for cholesterol in estrodial production play a factor? Should it be treated differently given the difference in causation? Really appreciate your ability to tactfully clarify and then create synopses of complex issues!! Thank you!!!
@JD-tn5tbАй бұрын
I agree about estrogen which is why I don't understand why so many Dr's think hrt is more of a risk for women over 65. I'm no Dr but I just think common sense says hrt would outweigh the risk for many woman when it comes to the brain, heart and bones.
@Petunia-fl9luАй бұрын
the reason cholesterol goes up after menopause is because it's used to make sex hormone and it is no longer doing that. I don't worry about it but my friends my age are all being told to eat low fat by their doctors. it's ridiculous. the main thing after menopause is don't overeat - stick to energy requirements, and exercise a lot. fat itself isn't going to 'cause' a heart attack when eating within a calorie controlled energy intake. it's so important to ditch the extra junk and know your calories after menopause. no one talks about energy intake - they just say 'switch to low fat milk and limit animal fats' but the low fat stuff (carbs) cause terrible health issues when consumed to excess - the limit should be on refined carbs!!!
@alfonso365Ай бұрын
Great info, love the channel!
@terrycameron9728Ай бұрын
Hi Gil Thanks for another intelligent overview of this fraught area. 🙏
@HSLSFirstАй бұрын
Very nice video that everybody can understand. We don't need any other video after this one.
@brucetattrie7341Ай бұрын
Amazing video. Among your very best.
@thebrocheckclub17773 күн бұрын
Diet plays a high role in protecting the endothelial layer. After moving to a whole plant-based diet and having had 3 CT angiograms, the evidence is clear to me that a healthy play is going on, resulting in vessel dilation and a widening of the artery wall.
@RealJonzukАй бұрын
Thanks for the quick resource to show people I care about
@bobwilliams9061Ай бұрын
“Bullets flying toward us…” this graphic was timely for you know who!
@brocklastname6682Ай бұрын
I was thinking the same thing, lol.
@anathardayaldarАй бұрын
Althought the video was published today, they must have been working on it for days. And he was thinking of that analogy for weeks or months. Still... what a coincidence.
@NutritionMadeSimpleАй бұрын
yeah this video was in the queue for a couple months just coincidence :)
@ladagspa2008Ай бұрын
Good video Gil.
@theancientsancients1769Ай бұрын
The most unfortunate thing we dont have reliable diagnostic for plaque that is not invasive! We need better more clear reliable methods to diagnose measure observe this
@reinasantosАй бұрын
Love your great explanations!!!
@kajonyАй бұрын
Once again an awesome video, Dr Gil, thank you so much! ( 3:56 Not important for the message… but for the bullet/ApoB analogy, bullets that have been fired don’t actually have any gunpowder in them!)
@brocklastname6682Ай бұрын
I caught that too. Dr Gil is not familiar with how pew-pews work.
@buppusАй бұрын
This is the perfect illustration for cholesterol deniers... They see valid evidence that factors impacting metabolic health have an impact on heart disease (e.g. trig/HDL ratio as a loose proxy for insulin sensitivity) and they insist that is the ONLY factor, thereby failing to see that two things can be true at the same time. Metabolic factors MODIFY risk, and sometimes with great effect, but there is still an underlying etiology that involves ApoB in a causal chain based on exposure over time.
@maarten7Ай бұрын
Very nice presentation and explanation. 👍💙
@meltedsnowman9637Ай бұрын
Amazing analogy and explanation!
@Lumencraft-27 күн бұрын
A meta analysis of your previous video content. Good idea👍
@alanwakeup3344Ай бұрын
Just tell me what to eat and which supplements to take doc, I don't want to think.
@seascape35Ай бұрын
LOL.
@bethbryant1370Ай бұрын
Excellent visual! ❤
@tomedwards1879Ай бұрын
Great presentation
@easyacademy8110Ай бұрын
A good summary!!!
@Andrefa75Ай бұрын
Hi Blood pressure, It weakens the barrier, I did not know. This Is such a good video. Thank you!!!
@alexm7310Ай бұрын
Very clearly explained - not easy to do! 😊
@adelabdelaziz-zh4zhАй бұрын
this is all you need to be in good health : eat a balanced healthy diet exercise sleep regularly take care of your mental health - stress lower substance abuse be surrounded with loved one do you consider something more ?
@AliceFarmer-bg4dwАй бұрын
Balanced diet? 1/3 calories from Fat 1/3 from protein 1/3 from carbohydrates?
@wumurphfuАй бұрын
Luck …… genetics factors
@adelabdelaziz-zh4zhАй бұрын
@@AliceFarmer-bg4dw balanced diet means not eating too much food or too little and a variety of food so you can get all the vitamin and minerals balanced also mean not highly processed
@brucejensen3081Ай бұрын
@@AliceFarmer-bg4dwyeah that can be good for shredding. On a maintenance diet, that is going to be high protein
@MindVersusMiseryАй бұрын
@@AliceFarmer-bg4dw Balanced diet: Eat real food, not too much, mostly plants.
@crystal5195Ай бұрын
thank you for the wonderful video
@kbmblizz1940Ай бұрын
It is why statistics should be taught in HS & must pass to graduate. The scientific methods should also be mandatory, as much as history or humanities.
@Andiness.Ай бұрын
While I'm a person that can't get enough statistics, there are some people who not only don't get it, but don't have the ability to. They're the ones who I'm more likely to bring the beautiful music and art into our lives. Fortunately the analogy that Gil has provided is helpful for those people.
@JW4REnvironmentАй бұрын
I like that you point to the scientific methods plural, because there are multiple methods. For example, a paleontologist typically can’t run an experiment in the same way a physiologist would on a living species…
@LiliquanАй бұрын
Of course, I got a dominoes ad for this video.😂
@realfoodcures29 күн бұрын
MVX is how to determine if you will live in the next five years. Metabolic Vulnerability Index Dr. Cromwell
@TommysPianoCornerАй бұрын
Dr William Cromwell (on the podcast with TheProof) said that in fact apo-b lipoproteins enter AND exit the artery wall by transcytosis (probably the incorrect spelling). Thus, the body wants them to pass through. The issue seems to be that some of them somehow get oxidized and as a result are unable to be transported out again. This is very different from Dr Dayspring’s description of apo-b ‘crashing into the artery wall’. If Dr Cromwell is right, then working out how they get oxidized might be a better way of preventing CVD
@SportsIncorporated28 күн бұрын
Really high quality lesson.
@lionelson7098Ай бұрын
The importance of cardiovascular health cannot be overstated, and three critical exams play a pivotal role in assessing and managing heart disease risk: the CT Angiogram, CIMT, and Calcium Score. CT Angiogram (Coronary Computed Tomography Angiography - CCTA): This non-invasive imaging test provides detailed pictures of the coronary arteries. It helps in detecting blockages or narrowing in the arteries, which can lead to serious conditions such as heart attacks. By visualizing the coronary arteries, doctors can make informed decisions about the need for further intervention or treatment. CIMT (Carotid Intima-Media Thickness): CIMT measures the thickness of the inner two layers of the carotid artery. Increased thickness can indicate a higher risk of cardiovascular events like stroke and heart attack. This test is crucial for early detection of atherosclerosis, allowing for timely preventive measures. Calcium Score (Coronary Artery Calcium Scoring): This test quantifies the amount of calcium in the walls of the coronary arteries. A higher calcium score is indicative of a higher risk of coronary artery disease. By identifying the presence and extent of calcified plaque, healthcare providers can better stratify patients' risk and guide treatment to prevent cardiac events. Together, these exams offer a comprehensive assessment of cardiovascular health, enabling early intervention and tailored treatment strategies to improve patient outcomes.
@lpg12338Ай бұрын
Great comment. 👍
@wumurphfuАй бұрын
Thanks 🙏
@thedeadman836126 күн бұрын
If you can dodge a wrench, you can dodge heart disease!
@tubby1Ай бұрын
Wow, I (or you) must be psychic because I was just about to suggest to you that you do a comprehensive overview of how the different risk factors for heart disease fit together, because I was confused as to how diabetes or blood glucose levels was a risk factor when Apo B was the thing that actually caused atherosclerosis. This video answered that. 👍
@keithdow8327Ай бұрын
Thanks doctor!
@groove9tubeАй бұрын
I have compiled a family tree and my mother’s parents and most of her six siblings died from heart disease at early age 60s. I have very high lp (a), genetically determined. Now I know why they all died so young.
@simonr9621Ай бұрын
Hey, do you know exactly how high your lp (a) is?
@user-ml2xh1jg1sАй бұрын
Outstanding, as always!
@nitrostudy9049Ай бұрын
Thankyou. That was a really usefull mental model that allows understanding of complex, interacting factors. [Note: I made an edit from useless to the correct word, "useful". I am unclear how auto-incorrect can change "useful" to "useless", but it did.] Maybe it would be additionally useful to explicitly discuss oxidative stress as a major domain weakening the bullet barrier? This would allow consideration of contributors such as obstructive sleep apnea, antioxidant poor diets, low vitamin D, dysbiosis, pollution (PM2.5), etc. Chronically elevated ROS levels (and factors that prevent this) can be discussed in terms of platelet activation (etc) contributing to contractile smooth muscle cell (SMC) activation -> migratory/ secretory SMCs that migrate to the intima and synthesise proteoglycans. Which, then allow 'capture' of postprandial remnant cholesterol. As the presenter mentioned, generalised inflammation, contributing to arterial plaque formation, is a major domain negatively affecting the bullet wall. One of my lifestyle pathways is determining whether I should use statins. I am aware of studies showing U-shaped all cause mortality curves with a minimum around ~ 3.6 mmol/L (140 mg/dL). My current research is to determine if ... with a CAC score of 1, normal BP, a diet mostly rich in antioxidants, vitD3/K2 (mk5&7) supps, exercise (resistance & walking), gly/NAC to boost glutathione, and good cholesterol (except LDL-C = 135 mg/dL) and apoB levels, intermittent fasting to reduce postprandial remnant cholesterol 'exposure, and now, also reducing exposure to PM2.5 and toxic people ... should I avoid statins. My understanding is that statins certainly have multifactorial benefits for at risk people. But, if the underlying factors leading to arterial inflammation and plaque formation are well managed, does taking statins then result in greater risks e.g. cancer) associated with low LDL-C? Fat and cholesterol are essential for good health. My current view is to avoid statins? Either way, I guess I am betting with my statistical life :)
@taylorcope9614Ай бұрын
Thanks for making this video! Very helpful
@liamtaylor4955Ай бұрын
Outstanding video, well done sir.
@gribble2979Ай бұрын
I've had high cholesterol since my thirties but no one in my family has ever had heart disease, so I refused to take any medications. A few years ago, I was given a thorough cardiovascular exam (the problem turned out to be pleurisy) and the cardiologist said I had the cardiovascular system of a teenager. I also had a CT angiogram last year and my score was zero. I'm in my late sixties and love to eat anything fatty - cream, butter, meat, and vegetable and fish sources of fats. Genetics are the key.
@FearzeroАй бұрын
Wrong. 1/3 of people with perfect CAC scores go on to have a heart attack or stroke. Soft plaque doesn't show up on those scans. Saturated animal fats shorten lifespan. It's high correlation in over 120 years of scientific research. 7 countries and Framingham studies.
@SteelyTheVanАй бұрын
Well it seems like you are a hypo-absorber and not a hyper-absorber. I’m the opposite and if I look at cholesterol it goes up.
@rima717nc29 күн бұрын
Excellent analogy!! Thank you!
@azdhanАй бұрын
Many thanks for sharing Dr Carvalho
@edl653Ай бұрын
Nice simple model that would be useful for those less inclined to dwell into the biochemistry mechanics of it all. My one criticism is with respect to diet. Diet IMO is the easiest and most impactful factor people can manipulate before a cardiac event happens. In this factor for those on a Western diet, the most critical item is Sugar (fructose) which is the worst component of a high carbohydrates diet. Fructose consumption directly impacts food cravings, fat storage, hunger (hunger and cravings have two different mechanisms), higher blood pressures (Increase Uric Acid which directly correlates to BP), glucose/insulin rollercoaster... Increase Sugar/Fructose consumption (Which also impacts other Carb consumption) directly tracts with increased rates and severity of most chronic diseases impacting folks in the West since the 1890s when consumption amount began increasing and spreading. Then in the 1970 with the creation of High Fructose Corn Syrup, and even cheaper form of Sugar, we are where we are at today. Cheers
@kygoАй бұрын
Great video! You said losing bodyfat effects both the components... Do you know if the effects are linier, ie going from 20% bodyfat down to 15% will be the same as 15% down to 10%? Or do the effects (improvements) start to taper off the lower your bf % goes?
@MakebuildmodifyАй бұрын
Hi Gil, thank you for all the great health tips. Question: Can you have high LDL and low apoB?
@kkmongАй бұрын
Still not sure why ldl particles pass thru the endothelium!
@adrianott5248Ай бұрын
You made a fantastic video about alcohol and mandelian randomization, explaining imo very clearly where our level of knowledge is right now. I would personaly love to see a video around the topic of training and heart disease. It sounds like a straight forward thing, but training is actually associated with both sudden cardiac arrest and heart fibrillation. So what do we actually know on the impact of training on different metrics of heart health, perhaps beyond associative studies?
@paulgaras2606Ай бұрын
Top notch.
@ThemataАй бұрын
KFC ad before the video 😭
@annoyedaussie3942Ай бұрын
Nothing wrong with KFC once a month or so.
@lutra-lutraАй бұрын
that is so helpful, thank you very much 🙏
@Shalyse1Ай бұрын
Can you do a video about glyphosates in food like oats? Health effects on humans?
@hctim96Ай бұрын
good stuff Doc, thanks...
@carnismiscancer2108Ай бұрын
Great video!
@TheRealJackMahofferАй бұрын
I recently had my bloodwork done, and I was shocked and disappointed at my cholesterol and ApoB levels. They were "good." They were all at what would be considered baseline. However, considering everything I do to keep those levels low, I was disappointed that my numbers were just at baseline good. I've been on a high fiber plant-based vegan diet for 5 years (no vegan junk food), I take Omega-3, psyllium husk, beta glucan supplement, soy protein isolate, I weight train 5 days a week and do a two mile walk on the other two, but my levels were just at baseline. My doctor said, "Well, imagine how bad it could be if you didn't do all that." He's right, and I know he was trying to make me feel better 😂. As of now, he says there's no need to take a statin, but we'd keep monitoring. I'm kind of bummed out how much genetics play into it. All my other risk factors were good, except my red blood cell count was high, but I've always known that about my family history and donate blood every 3 months.
@plantstho6599Ай бұрын
Whew, I thought you were going to say exercise minimizes risk.
@AgrippaMaxentiusАй бұрын
Ive just discovered at the age of 35 that i have Multivessel Coronary Artery Disease. To say I am terrified would be an understatement. I have already switched to WFPB, stopped the smoking etc. The occlusion is 25-40% in 3 arteries. 30-40% in 2 and less than 25 in another. I am hoping that while I cannot turn back time I can do what I can to fight this. But I am not feeling very confident. I will get Apob tested, I am in Portugal if anyone can recommend any good lipidologists or any advice in general. Thanks Dr Gil
@hyevoltageАй бұрын
I’m assuming the “barrier” is or includes as a large factor the endothelial. You said outside of the genetic lottery there isn’t really a good way to improve its protective factor, but, and this is a segue I thought you were going towards given the recent Esselstyn announcement, aren’t there things like nitric oxide to increase the health & function of it, or is that just a temporary boost and/or not yet proven with large enough RCTs?
@FearzeroАй бұрын
Exercise, low fat, sodium and sugar diet, more whole plants. Nitric oxide rich foods have short term benefits but leafy greens contain a lot of L Arginine which activates mTor. You don't want that because it will shorten your lifespan. Too much of anything is bad.
@Dermsurg1Ай бұрын
Why hasnt Zetia shown a protective effect as monotherapy since it effectively lowers ApoB
@donwinstonАй бұрын
Zetia protects people from cardiovascular events. What are you talking about?
@georgecavАй бұрын
@@donwinstonNot by itself which it should if all this is so ApoB modulated. Check out Wellnowdostor and that doctors video on the topic
@tomgoff7887Ай бұрын
The EWTOPIA 75 trial showed a protective effect as a monotherapy.
@ÁzsiábaSzakadtamАй бұрын
It lowers for the so called "absorber" type mostly. These are who tend to absorb too much cholesterol from the intestines. Statins act on the cholesterol receptors.
@NutritionMadeSimpleАй бұрын
hi, as explained above, although the largest trials with ezetimibe (like IMPROVE-IT) use it on top of statin (for precedent reasons), at least one outcome trial has shown reduction of composite cardiovascular risk with ezetimibe as mono therapy: www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.118.039415 (when evaluating efficacy we always want to look at magnitude of reduction of LDL-C/ApoB which predicts risk reduction)
@SashaHighsmithАй бұрын
Thanks to your videos, I was tested and found I have very high ApoB and am now taking a statin and diet measures. You may have saved my life! Thank you! Would you mind explaining cholesterol in fish? Is it good cholesterol or are the omega 3s so helpful it makes eating fish worthwhile?
@Michael-oj6rtАй бұрын
Can a diet rich in foods that increase nitric oxide production help with the barrier side of risk?
@afzalhussainshah8006Ай бұрын
Yes beet root juice did wonders for me
@bryanspencer4856Ай бұрын
Great stuff!!!
@joshuamiller7740Ай бұрын
lol dude doesn't know much about bullets and gunpowder but he knows his stuff on nutrition
@MJB0110Ай бұрын
Thx Gil for the info. If someone asked you if a 7 month old baby was just beginning to eat things like eggs, what would you recommended the egg should be fried in? They currently fry in ghee (Saturated Fat) I’m sure that’s not the right thing for a baby based on clinical evidence, but just wanted ur thoughts on this.
@jmwhittАй бұрын
Plaque is almost indistinguishable from clots in vessels on CT per a Radiologist. Clots are the a main culprit. Minimize sat fat and estrogenic foods, improve blood flow, lose belly fat, work out. Fasting can help lower Lpa and maybe decrease plaque. Infections can cause clots, take aspirin or similar during flu/infection. Low or 0 CAC can still mean soft plaque is there.
@Colin-yu7pcАй бұрын
Estrogenic foods?
@maenad1231Ай бұрын
@@Colin-yu7pc Alcoholic beverages _(smaller portions, less drinks, lower abv is better if refuse to give it up)_ Processed Meat & Red Meat _(a 2018 review found the estrogen levels in milk isn’t typically high enough to effect human health)_
@hctim96Ай бұрын
@@Colin-yu7pc Soy...
@Colin-yu7pcАй бұрын
@@hctim96 Soy isn't an "estrogenic" food though, it lowers rates of estrogen breast cancer
@niamhleeson3522Ай бұрын
If eating soy causes plaque then why do Japanese people eating a traditional diet live so long eating tofu, natto, rice, and vegetables? "Estrogenic" foods have very little to do with plaque accumulation or clotting and natto is actually a food that reduces clotting. Stop talking nonsense, please.
@aboutsuppliesАй бұрын
Fully active matrix gla protein protects the arteries from plaque build-up. To understand how it works, is to know that mgp is found in mice too. Researchers knocked out mgp from mice. They all died within 6 to 8 weeks of age. They all had arteries constricted by plaque and many had burst arteries.
@southern842Ай бұрын
From eating to getting atherosclerosis, what's the full mechanism of how that happens?
@FearzeroАй бұрын
The video explains that.
@davedewsnap288Ай бұрын
What’s your take on so called ‘plant sterols’ in margarine that have been clinically shown to reduce cholesterol?
@bedtimestory1318Ай бұрын
Can you do some vids on organic food, pesticides, plastic in food, obesogens, supplements?
@enstipsАй бұрын
Great summary, but you never talk about sleep apnea which is a major driver of atherosclerosis.
@AliceFarmer-bg4dwАй бұрын
Interesting. I have always wondered if sleep was related. Poor sleep is a main driver for plaque in arteries? Do you have any evidence or information to support that statement? If there are studies that prove that, then I am done with medical professionals. Including this channel.
@NutritionMadeSimpleАй бұрын
interesting, will keep in mind for future content, tks!
@enstipsАй бұрын
@@AliceFarmer-bg4dw just write "sleep apnea atherosclerosis" on google scholar and you will find a ton of studies.
@enstipsАй бұрын
@@NutritionMadeSimple Great, sleep apnea and sleep quality is often overlooked in the field of health.
@remy8587Ай бұрын
I also read it was a risk factor for high blood pressure which is a contributing factor to atherosclerosis. Please link the study to us!
@baconinvader24 күн бұрын
Hi Gil, I have a question. I have a family member who claims their diet and lifestyle gives them a very low risk of heart disease and MACE. However, when I shot them with several bullets as per your model, they still experienced severe negative health outcomes. Is this to be expected, or do you think they are some kind of outlier? Unfortunately, I'm having trouble finding additional volunteers to repeat this experiment with.