Saturated Fat with Dr. Ben Bikman

Рет қаралды 57,516

Ай бұрын

In this episode of The Metabolic Classroom, Professor Ben Bikman, an expert in metabolic research, discusses the debate surrounding saturated fat and its impact on insulin resistance.
Dr. Bikman addresses misconceptions about saturated fat perpetuated by proponents of plant-based diets, who often blame meat-based saturated fats for insulin resistance. He refers to his own 2011 research, highlighting the role of toll-like receptor four (TLR4) activation in inducing inflammation and insulin resistance, particularly stimulated by saturated fats.
Acknowledging limitations in his earlier work, Dr. Bikman transitions to discussing fat digestion and absorption, setting the stage for studies on the impact of dietary saturated fat on metabolic outcomes. He cites a study by Volk et al. (2014) contradicting the direct link between dietary saturated fat intake and plasma saturated fat levels. Further, he discusses research challenging the low-fat emphasis of diets like DASH, including a study by Chiu et al. (2016) showing comparable blood pressure reduction with a high-fat version.
The lecture also covers a meta-analysis by Choi et al. (2020) supporting the benefits of ketogenic diets high in saturated fat for glycemic control and insulin resistance.
Dr. Bikman emphasizes the importance of considering context, suggesting that saturated fat consumption without excessive carbohydrate intake may not necessarily lead to insulin resistance. However, he acknowledges studies indicating potential concerns with high saturated fat intake in hypercaloric, high-carb diets, advocating for balanced macronutrient consumption.
#InsulinResistance #SaturatedFat #MetabolicHealth #NutritionScience #HealthEducation #DietaryMyths #CellBiology #ResearchInsights #FatDigestion #KetogenicDiet #CardiometabolicHealth #DASHDiet #Inflammation #MedicalResearch #HealthDebunked
00:01 - Introduction of the topic of saturated fat and insulin resistance, highlighting common misconceptions and his expertise in the field.
02:33 - Role of TLR4: Research on toll-like receptor four (TLR4) activation and its connection to inflammation and ceramide synthesis, leading to insulin resistance.
07:05 - Fat Digestion Primer: Explanation of fat digestion in the small intestine, emphasizing the formation of chylomicrons for fat transport into the bloodstream.
11:55 - Study by Volk et al. (2014): Key study that challenges the idea of dietary saturated fat directly increasing plasma saturated fat levels, despite high consumption.
16:41 - High-Fat DASH Diet Study: Research comparing a high-fat version of the DASH diet to the standard low-fat version, highlighting similar blood pressure reduction but improved lipid profiles with the high-fat diet.
19:46 - Meta-analysis by Choi et al. (2020): Demonstrating the benefits of ketogenic diets, typically high in saturated fat, in improving glycemic control and insulin resistance.
21:40 - Historical Trends: The paradox of decreasing saturated fat consumption over time while insulin resistance rates have increased, suggesting a more complex relationship.
25:58 - Overfeeding Studies: Studies showing that overconsumption of carbohydrates, particularly refined sugars and starches, can increase liver fat and saturated fat production, contributing to insulin resistance.
27:09 - Study by Luukkonen et al. (2018): Study indicating that in a hypercaloric, high-carb diet, high saturated fat intake may worsen insulin resistance compared to high unsaturated fat intake.
28:06 - Conclusion: The need for nuanced understanding, context, and critical appraisal of research findings regarding the relationship between saturated fat, carbohydrate intake, and insulin resistance.
www.insuliniq.com
www.jci.org/articles/view/57144
pubmed.ncbi.nlm.nih.gov/26718...
journals.plos.org/plosone/art...
www.ncbi.nlm.nih.gov/pmc/arti...
consensus.app/papers/glycogen...
consensus.app/papers/shortter...
diabetesjournals.org/care/art...

Пікірлер: 363

@carolynhunt7333 Ай бұрын

My granddaughter is headed off to medical school after having just graduated from BYU. I’m so happy that Dr. Bikman was her endocrinology professor. She’ll be a better doctor for having had his instruction.

@proudtobeweird Ай бұрын

😯 She is a lucky lady … learnt from the best 😊

@jobrown8146 Ай бұрын

Wow, that's really good to hear.

@vonticehembree6083 Ай бұрын

Lucky little lady !!! I wish I could sit all day in his classroom

@Petunia-fl9lu Ай бұрын

how wonderful!!!! you must be so proud!

@albertdowrn 8 күн бұрын

I was just thinking after listening to another podcast when he explained he was teaching pathophysiology how I would of learned so much more.

@Crimepaysaskapolitician Ай бұрын

Professor Bikman your hard work is very much appreciated. You have changed my life for the better, I can't thank you enough.

@saeedshirvani8052 Ай бұрын

Dear Dr Bikman Thank you for clearing up all the falsehoods and proving that millions of people have suffered for decades due to the greed of big pharma

@wade-buehler Ай бұрын

And speaking of Calgary... Hi from Calgary! Now, can you give my doctor a call? He's in a PANIC because my LDL is through the roof since I went all Keto last August. In my lifetime, I've lost more than 300 pounds. After being treated for t-2 diabetes for 30 years, I almost lost my foot in Nov 2022. The following August, I came across Dr. Pradip Jamnadas, who eloquently explained it. I did everything he and so many others have said, I cut out high carbs, processed food, and seed oil, lost 70 pounds, triglycerides way down, HDL up and LDL really up a complete reversal of t2 diabetes A1C of 5.7... after all of that. He wants me on a staten and to stop consuming saturated fat. Hello, news desk, I think I found the problem.

@nevillegoddard4966 Ай бұрын

@@jigglesandwich You need to either educate your doctor or FIRE him!

@wade-buehler Ай бұрын

@@nevillegoddard4966 I know, right. Unfortunately, it's not just my doctor. Sadly, I think it's the majority of them, especially in Canada. I spent more than two hours explaining the relationship between triglycerides, HDL, LDL and VLDL and how they relate, especially with a low-carb diet. I gave him a couple of links. I think he's gonna be alright, but it took 40 years of sales and marketing experience to bring him around. The sentence that hit him the hardest was "You treated me for diabetes for more than 30. years and I almost lost my foot. Three weeks on a low-carb high-fibre, moderate protein diet and I was off all diabetic drugs in two weeks and a perfect A1c 6 months later." Now that's medicine.

@aleksandrazimpel8097 Ай бұрын

You don’t need doctors in your life. Take responsibility for your health fully. Don’t let them gaslight you. 2 of my brothers had heart attacks and have stents and claim it’s theirs genetics lol. Ones wife is medical doctor specializing in treatment of diabetes and his daughter is big harma rep. Younger brother’s is medical doctor and his wife worked for big harma now retired in the early 70’s. Statins since at least 20 years and other meds. Now fully injected with the newer marvels of pharmaceutical technology of nano lipids and synthetic modified RNA. They have other problems to. And they blame their genes because doctors determined they must have bad genetics. That twisted lol

@chewiewins Ай бұрын

Well done on reversing HbA1C! I did same with whole food, plant based. HbA1C normal, BP 110/70 and LDL normal.

@hp-cs7mx Ай бұрын

Let your your doctor panic all he likes! Not your job to worry about that. You have done so well, get a supportive doc for where you are now. Good luck from Australia !

@akhusal Ай бұрын

Dr David Unwin gave the advice to his patients to eat plenty of saturated fat, meat, eggs and salt but avoid carbohydrates (bread, rice pasta, bananas, apple etc). Hundred patients lost weight, improved liver and kidney function, came off diabetes medications saving £70,000 in medicine costs for ten years. He recorded all stats over several years and published them in journals. If only every Doctor would do their job and above all first do no harm (conventional practice results in amputations, heart/kidney failure etc).

@jobrown8146 Ай бұрын

Thankfully Dr Unwin was one of the first videos I found after learning that I had diabetes and found out about the low carb lifestyle.

@jeffj318 Ай бұрын

@@jobrown8146Keep it up. Congratulations! 🎉

@jax9349 29 күн бұрын

I love Dr David Unwin, his journey is so inspiring.

@jobrown8146 29 күн бұрын

@@jax9349 Yes, and I love the fact that he has documented the progress of his patients.

@allfunnydogsstories2129 28 күн бұрын

I watched this three times in a row to understand everything you were saying and the third time I started crying because our human body is so unbelievably beautiful. I understand now what’s happening, and the complexity of it is so mind-boggling. At the end we are simply left with only one thing to do, and that’s to treat our body with the respect it deserves ❤

@eddkennedy6458 25 күн бұрын

Yeah and refuse the clot shots

@johnwoodard8717 Ай бұрын

About 2 1/2 years ago when i was diagnosed with T2 Diabetes my A1C was 10.4. I went on the lowest dose of metformin possible and went on a low carb high fat diet. 3 months later my A1C was 5.4. The only time it went up was when I was eating Mission Low Carb Tortillas regularly (they're a lie; a glucose test showed my blood glucose spiked to 154 just from eating one). My A1C went to 5.7, but more relevant to this conversation is that my Triglycerides spiked to 320. Cutting those out, 3 months later my A1C was 5.4 again and my Triglycerides were 128. 3 months after that they were 99. I didn't change anything else about my diet. Today I'm at 5.4-5.5 with no medication at all, and I'm not super-militant about my diet but I do avoid GPS (Grains, Potatoes, and Sugars) pretty heavily.

@GummyRiches Ай бұрын

Next time you eat any kind of tortilla brand, keep some in your pantry and see how long it will last. It will stay fresh for months, meaning super high amounts of preservatives, let alone, bunch of unnecessary ingredients. It's just BS. Any type of bread you buy at your local grocery store are just all BS.

@JohnSmith-zs1bf Ай бұрын

So strange I'm fairly lean (like 14 to 16% bf) and even on keto for 6 months my a1c only drops to 5.6 at best

@johnwoodard8717 Ай бұрын

@@JohnSmith-zs1bf I also do a lot of Zone 2 exercise to improve MItochondrial function, which has been tied to any number of metabolic diseases, including T2D. When I stopped that because I was walking every day my A1C went up a tenth.

@JohnSmith-zs1bf Ай бұрын

@@johnwoodard8717 cool. what do you do for zone 2? jogging?

@johnwoodard8717 Ай бұрын

@@JohnSmith-zs1bf Biking. I can't get out of one 1 walking, and I can't not be in zone 3 or 4 jogging as I'm a terrible runner. Biking for me is the easiest activity to control my zones. Even with hills so long as I leave my ego at home I have enough gearing to not leak out of zone 2 more than a minute or so.

@meatdog Ай бұрын

Thanks a million times over. I am down this rabbit hole and cannot get enough of this education you are providing. I wish I could turn back my clock and pursue this research as my lifes work, also. Your contribution is priceless and I hope you are able to continue for a very long time. I read your book from cover to cover on Saturday and just could not put it down. I will be studying and subsuming it until the pages wear out. Sincerely.

@donaldmcpherson3226 Ай бұрын

What wonderful comment.

@jamescalifornia2964 Ай бұрын

It's interesting how we become scientists while learning about our physiology 😉👌

@paulhailey2537 Ай бұрын

Eating a Tasty Ribeye at this very moment with a couple Eggs too

@jeffj318 Ай бұрын

That's the way to do it from a former plant based eater and now carnivore.

@MyKeiKat Ай бұрын

❤

@danielcohen24 27 күн бұрын

Indeed! Carnivore is the PHD

@paulhailey2537 27 күн бұрын

There's No Carb or Sugar that Tastes as Awesome as I Feel and just keeps getting Better every Day 💪

@smthB4 Ай бұрын

What an irony! Saturated fats are to blame after all, but not dietary saturated fat, rather saturated fat made from excess carbohydrates as a result of dietary guidelines! My ‘model’ of insulin resistance has just taken a couple of steps forward thanks to learning this 😊

@Neihlos Ай бұрын

What a fantastic way to start a Tuesday.

@johnmadany9829 Ай бұрын

For me it's a fantastic way to start a Thursday😊

@kriscook2449 Ай бұрын

Thanks, Professor Bikman. You have expertly conveyed your message with your careful choice of words. You ROCK!

Ай бұрын

it is a Privilege to listen to Mr. Bikman 🍀👍

@notsatch Ай бұрын

My scrambled eggs and sausage, fried in ghee, tastes even better than usual this morning!

@MrTrda Ай бұрын

😋

@jobrown8146 Ай бұрын

I had bacon and onion fried in butter and then scrambled the eggs into the pan with them for dinner last night. Very yummy and satisfying.

@ronaldlenz5745 Ай бұрын

I'll be breaking my overnight fast with bacon and eggs at about 11 a.m. I've already had a brisk 4 mile hilly walk, viewed this graduate level lecture, and planned dinner, a 8 oz beef steak and steamed broccoli. LG!

@salobrena6442 Ай бұрын

I feel like a superstar now.. vldl is 14, ldl is 191, hdl 102.3 and my triglycerides are 71.. this was after 1 year on carnivore. This diet works and improves nearly every single thing. Even my car is running better.

@JMK-vo8pv Ай бұрын

Two years ago I consulted a "preventive" cardiologist for my diabetes and known coronary artery disease. He just about threw me out his office when I told him I was considering a "ketogenic" diet. Then he went on to say I needed to be on a "plant based" diet, preferably the "Mediterrranean" diet, and that I needed to immediately embark on regular injections of PCSK9 inhibitors. Unfortunately, I believe that my experience is NOT rare. Thank goodness we have great scientists like Dr. Ben Bikman to set the record straight and help us progess toward better metabolic health!

@leticianedilskyj7060 Ай бұрын

It sounds like my same cardio. Does the last name starts with K?

@meatdog Ай бұрын

I was more fortunate than you. I had a heart attack during my stress test at age 46. My cardiologist was doing thr test. When itcsll settled out he told me to immediately stop being a vegan because it caused my heart issue. That was in 1998! He was way ahead of his time and I am eternally grateful. Now as a carnivore, at age 73 I'm super healthy with no heart problems and perfect blood pressure, blood sugar, weight and no joint pain. They are few and far between.

@brachiosaurus6541 Ай бұрын

That's the same advice a woman who suffered a heart attack was given to. Now she's gorging on bread, croissants, jam and coffee loaded with sugar every morning. She is high every day from so many carbs and confident in her doctor's advice. A friend of her already passed away and was eating an extremely hypocaloric diet based on carbohydrates and veggies. She had more wrinkles than a raisin.

@iyadkhourdok4316 Ай бұрын

In an amazing way, you break down all that science and make it clear to everyone. I love your podcasts. keep going, Dr. All respect 🙏

@idoiam.2351 10 күн бұрын

I study nutrition, but you and Dr Lustig are my real professors. Thank you ❤

@alexanderu4208 Ай бұрын

Eating fish and butter while watching this episode..

@johnrecker Ай бұрын

Eating beef patties & bacon while watching this episode..

@TagiukGold Ай бұрын

Scandalous.😅

@websterdoris3014 Ай бұрын

Eggs and bacon 🎉

@davidnannalockwood3133 Ай бұрын

Fatty beef patty with salt and extra tallow for me.

@bhmcl4131 Ай бұрын

Whatever you do don’t batter it!

@pinanay Ай бұрын

As a cell biology major in college and a med school dropout, I have thoroughly enjoyed this lecture. Thank you, Dr. Bikman. I have subscribed to your channel.

@CarnivoreScott Ай бұрын

Fat Tuesday is the BEST day of the week!! Thank you Dr. Bikman. Oh and the glasses ROCK! I'd like to say you DASH'd my hopes, but in truth you have once again reinforced the idea of how a proper human diet includes saturated fats. Well done, and THANK you for providing links to the quoted studies.

@davidcorbit3931 Ай бұрын

Dr... I absolutely love the way you dig in and truly teach, you are a refreshing breath of medicine . Thank you.

@willemvanriet7160 Ай бұрын

On a keto diet I eat huge amounts of saturated fat through bacon, red meat, eggs etc. and my triglycerides are ROCK bottom at 43 and HDL is a VERY healthy 84 and my waste circumference is 34. Take that food industry that's forever trying to hook me on carbs!

@quisge Ай бұрын

Your comments about high-carb-high-fat diets being terrible reminds me of mechanisms in the Randle Cycle. I'd love to see an episode dedicated to that topic and its relationship to insulin resistance, assuming the Randle Cycle is indeed a valid mechanism in the cells. I'm still trying to wrap my head around how it works and whether its even valid.

@PL.Borneo Ай бұрын

The last study where saturated fat is combined with hypercaloric high carb diet brings to mind the Randle cycle where there’s a danger in combining fat and sugars together.

@stanfordlawgrad7202 Ай бұрын

Excellent explanation. Dr. Bikman sets the example of properly done science, and simple, easily understood concepts for the lay person.

@user-ls3ew3ct5r Ай бұрын

Dr Bikman - Thank you, so much, for all the research you do, and the care you take to keep me informed of the truth of the matter! If I had to figure this out myself, I’d be lost. I appreciate you!

@DynoDeso Ай бұрын

Insulin Resistance is a protection mechanism of the cell against glucose. All by the beautiful mechanisms of the Randle Cycle

@amazingmikemed Ай бұрын

Ben there is a study that compared DASH to low carb in Type 2 diabetics. Low carb reduced blood pressure twice as much as DASH. If you put DASH into the search on Dr Berry's channel he talks about it. The study not that old.

@petrapiciacchia2456 Ай бұрын

1988 was a great year, not only did Calgary, AB host the Winter Olympics I was giving birth to my first child during the event in Fort Mc Murray, AB. Great memories and as well , great video.

@Margaret2494 Ай бұрын

Thank you for explaining this in a way that I can actually understand! You are truly a skilled professor and researcher, and your videos are a joy to watch.

@MrBilartur 14 күн бұрын

I’m following you from 2021, and my health improved dramatically since then, thank you so much. You’re my best messiah !! Greetings from France 🇫🇷

@nealbrown2978 Ай бұрын

Thank you, Dr. Bickman . I always look forward to watching.

@dorisvoo9743 Ай бұрын

Someone need to inform Ms Charmaine Dominguez about these studies. She's a plant based dietition been all over youtube making shorts telling ppl that sat fat causes IR. When I asked her to explain the mechanism she said she will once I join her free training programme. Unless she knows something Dr Bikman doesn't which I highly doubt.....

@ajadkins1555 Ай бұрын

Thank you for all you do! ❤

@warrenbach Ай бұрын

Excellent presentation. Thanks for sharing your helpful information.

@78cheerio 27 күн бұрын

I LOL when you said miserable diet. You NEVER complain, judge harshly, or made jokes. You are so very straight up. I was so surprised when you used the word miserable that it got me. Not to encourage you too much but that little Segway from your usual personality was great. Excellent work. This is an important topic and you are the first I’ve seen tackle this saturated fat in so much detail. I watch because I have stubborn high trigs. They do go down on low carb but I worry about the fat. My gene report from FYF by Dr. Rhonda Patrick says I might have trouble metabolizing saturated fat. I’m supposed to increase monounsaturated fat. I think better outcomes like Bp,sleep, trigs might be more important.

@Cya-bebetter Ай бұрын

I love nerding out with your videos; they inspire me to continue my weight loss, health journey in the most educated way. I feel 20 yrs younger with this lifestyle change. Thank you for providing us with the science. ❤

@nevillegoddard4966 Ай бұрын

Excellent video Prof. Bickman! Thank you!

@joshtoten Ай бұрын

Just finished my eating window with some delicious andouille sausage while watching this. :) Keep doing what you do, Doc!

@carlor.s.4742 17 күн бұрын

Once more a metabolic lecture which is so well organized & conceptually progressive that following along & learning is a joy. Well done!!

@jimjackofall1510 Ай бұрын

Wonderful talk. Thank you so very much

@nancygorham5908 18 күн бұрын

Excellent info. Thank you!!

@user-ss4xs4th2r Ай бұрын

Thank you for the great lecture and all you do!

@user-rb4pb2hp7m Ай бұрын

Thank you, Dr. Bickman, for clear and understandable way of explaining complex issues!

@DelikatesyLafuente 24 күн бұрын

Thank you very much. Wonderful video

@Snowsea-gs4wu Ай бұрын

Thank you Dr Bikman!

@ninogogoladze6974 Ай бұрын

Thank you for another fantastic video, Dr. Bikman

@TurboE30M3 Ай бұрын

This is a fantastic lecture, Dr. Bikman!

@debbiesue4287 Ай бұрын

Thank you❤ so much for all your hard work and wisdom ! Greatly appreciated!!

@3buzzy Ай бұрын

This is great!!! Thank you for you work and sharing this information. You are helping the world be healthier and better informed!

@melissawitherspoon9094 Ай бұрын

Thank you, Dr. Bikman❤

@sharieddinger9715 Ай бұрын

Wow - this is great information explained very well. Thank you ☺️

@joannsmith9 Ай бұрын

Thank you for taking the time to help all of us who aren’t doctors understand and therefore benefit from factual information.

@vthirteen Ай бұрын

Great presentation.

@Thundercloud1969 Ай бұрын

Dr. Bikman, I say it again, you are my hero ! Your info makes my work so much better, keep it comming!

@nafisaaptekar3601 27 күн бұрын

Great explanation as always

@nelsontang1055 Ай бұрын

thanks Dr. Bikman, great video, this is very informative, excellent info.

@chiararegolini Ай бұрын

Amazing explanation !!! Thank you very much! I love your work and how you explain all the mechanism! Thank you for all you do!

@websterdoris3014 Ай бұрын

Thank you Dr Bikman ♥️💙♥️

@charlesdowning5899 Ай бұрын

Excellent video! Thanks!

@nancyarchibald9095 Ай бұрын

Great subject 👌 Dr . I'm on my ketogenic way of eating (once again.) This time around is significantly different because I need to make this my lifestyle. **I am adding more fat this time. I'm adding more marbled red meat, also, extra butter to my meals to achieve longer lasting saity. I'm rarely hungry and losing about 2 lbs per week. Im 68yrs old and pretty much sedentary because of agressive, widespread osteoarthritis. I really enjoy your podcasts and shares. 🎉

@evahullful 7 күн бұрын

Mind blowing! Thank you sir for educating us

@frankangelone7989 Ай бұрын

Excellent video!

@hmlxur54 Ай бұрын

I learn so much with each presentation, thank you for clearing any doubt on saturated fat in reference to serum fat.

@greenwealth7781 14 күн бұрын

I am glad to hear ...

@surfinwaves4769 Ай бұрын

Brilliant, so clear, thank you!

@donnafoust5172 Ай бұрын

Great lecture!

@mariocovino8250 Ай бұрын

Thankyou. Just so important to get this information from an authoritative source. 👍🏻

@jeniedwards5999 Ай бұрын

Loved your book, love this info you share freely. Thanks so much, you've changed the way my family of 8 eats!

@jobrown8146 Ай бұрын

Thank you once again.

@OemarMalawat-mu4sc 29 күн бұрын

Thank you very much for educating...... greetings from Indonesia

@RobertaRavasio-ru4dd 18 күн бұрын

Dr.Bickman, I'm not a MD but your Speeches are so easy to understand!! My son is about tof fnish to study medicine ad University, in Italy, and I can't talk with him about ketogenic diet, saturated fat...I think that many of the things you explain n your videos are not yet aknowledged by general pratictioners and/oe ininternationalguide lines... Thank you so much!!!

@glennpesti6519 Ай бұрын

So much fantastic information, thank you

@cookingketowithlee5001 Ай бұрын

Another great lecture! Thank you ❤

@CoyoteWindRanch Ай бұрын

Excellent times infinity! Loved it!

@marytaylor3675 Ай бұрын

My Doctor pushes the DASH diet. I push the KETO diet and have had great results!

@twn5858 Ай бұрын

What do you have a doctor for? They're just pill pushers.

@christinaperez254 Ай бұрын

Yay! Lets learn!🙌

@drhanafayyad4347 8 күн бұрын

You are an amazing knowledgeable lecturer

@sgg3745 Ай бұрын

Great one

@bruceprigge5212 Ай бұрын

Thank you! 😊

@jcarlin596 Ай бұрын

Very informative

@sarahg1077 Ай бұрын

What kind of fat is human body fat? Like, what never made sense to me is that people would say not to eat saturated fat… but what if human body fat is saturated fat??? I have done water fasts between 3-17 days long. On a most recent 7 day water fast, I had my blood drawn on day 5 and of course, my cholesterol and triglycerides were elevated. Now just looking at that bloodwork would appear that I am not healthy (according to mainstream doctors, like mine.) But once I began eating my usual low carb diet, my numbers went back to normal. Just wondering if the elevated because I was literally only consuming body fat (saturated fat???). The body is fascinating!

@tonysangster7383 Ай бұрын

Thank you for such a well presented talk, the bravery to critique your own work and explain its misinterpretation by others. As a T1D I now better understand why, if my bsl happens to be higher than ideal, that avoiding intake of both carbs and saturated fat is best avoided, until blood glucose levels return to my normal range say, 70 to 120 mmg/dl (or 3.8 to 6.7 mmol/l. The wisdom of doing so for carbs is self-evident bot was not so much for saturated fat as perversely a highish blood glucose level sometimes makes me feel hungry. I also have found out that really those with T2D or T1D are likely to become insulin resistant to some degree- - in T1D because combating blood glucose rise with peripheral insulin administration cannot match the input and intricacy of insulin infused into the portal vein as a meal is arriving from eating, higher doses are needed. At 57 years on insulin; since age 13, and 5 years on a ketogenic diet with insulin injections (scar tissue making insulin absorption too unreliable for insulin pump infusions of insulin) consistent HBA1cs of 5.2% have made life so much better. I wish that diabetes education about low and very low carb diets included the caution about not eating carbs and saturated fats when blood glucose levels are elevated.

@glenncivale6824 Ай бұрын

Brilliant!

@kathyconery Ай бұрын

Thank you for the presentation. Wondering if you have any concerns re competing interests of the sponsors of the 2014 Volk study?

@JR-jn8jp Ай бұрын

Thank you very much for this presentation. Do you by chance have the cite for the paper at 18:00 regarding outcomes of low vldl vs ldl? Thank you

@hamiltoneast Ай бұрын

Bravo!! Highly accessible presentation (for the exact question I'd ask Ben if we met.)

@roseperozzi6730 Ай бұрын

Thank You ❤🙏🏻🙏🏻

@donaldmcpherson3226 Ай бұрын

Wow! The Metabolic Classroom is an absolute TREASURE TROVE of useful knowledge. I am too old to learn enough to build bridges in my remaining life, but I can learn enough to progress from building with tinker toys to building with an erector set. Thanks for the progress toward enlightenment.

@rodmacgregor7774 28 күн бұрын

Thanks

@insuliniq 24 күн бұрын

Hi Rod. Thanks for your kind contribution. Certainly not expected, but appreciated. Thank you.

@edwcnj1 Ай бұрын

To me it seems that your discussion strenghtens the argument of the randle cycle when fat in presence of high sugar contributes to insulin resistance.

@DynoDeso Ай бұрын

It's not really an argument, the Randle cycle is an undisputable fact and the fact that it isn't taught (barely) is criminal.

@victorialove1628 Ай бұрын

Could you comment on your thoughts about the Randal Cycle.

@garyjackson4054 Ай бұрын

Would be interested in IR and effects on puberty

@albertdowrn 8 күн бұрын

What upsets me the most is people who should be curious about this kind of information don't care one bit. I just shared this on my Facebook page. I'm an RN many of my Facebook friends are in the healthcare field. I won't get one comment, but if I post a picture of my cats. Katy bar the door!

@meatdog Ай бұрын

I'm exteemely curious about ceremides. Are the ceremides advertised in skin lotion dangerous as they are absorbed through the skin??? And do they contribute to insulin resistance. And are they molecularly the same as blood ceremides? I have lots of questions about this process.

@carlosunidos Ай бұрын

Thanks!

@insuliniq Ай бұрын

That is very kind of you, Carlos. Not at all expected buy appreciated. Thank you.

@Mark4Jesus Ай бұрын

Hi Dr. Ben. In the study you mentioned where sat fat in blood caused IR, what was the composition? Was it myristic? palmitic? stearic? lauric? capric? caprylic? caproic? All of the above? I couldn't find the study. Thanks!!!

@bobsundquist2039 Ай бұрын

Once again another excellent talk. Could you please comment on saturated fat and Apo B. The big argument now with saturated fat is it causes an increase in Apo B.