Intro to Lipids & Lipoproteins: Why there is no ‘bad’ or ‘good’ cholesterol | Peter Attia, M.D.

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Peter Attia MD

Peter Attia MD

2 жыл бұрын

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About:
The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 40 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more.
Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life).
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Пікірлер: 1 000
@pavelchorda8425
@pavelchorda8425 2 жыл бұрын
Honestly, I like this format not because is 12 min long, it's because you explained in a way that most of the people can understand it. Congrats
@CJP3626
@CJP3626 2 жыл бұрын
Appreciate you publishing this. It reflects the intelligent and fact based commentary your following has grown to respect, and expect from you.
@AnnhilateTheNihilist
@AnnhilateTheNihilist Жыл бұрын
As opposed to the 25hrs of podcasts? How shocking!!!!
@SlavaEremenko
@SlavaEremenko Жыл бұрын
Gonna burst your bubble and inform you that an average person can’t even come close to understanding this. Did you know that 54% of Americans can only understand what they read at a 5th grade reading level or less and have trouble inferring things from what they read?
@buckmurdock2500
@buckmurdock2500 8 ай бұрын
doesn't take long to tell a lie.
@bekeneel
@bekeneel 7 ай бұрын
There is bad cholesterol tho, or however u call it. But it's not exactly the LDL, only a smaller part of it. So the total of your LDL doesn't say that much. Triglycerides is one of the other worst to avoid. Except for like those in coconut oil, imo. This is perfectly explained in this video "The BIGGEST Risk Factor For Heart Attack" by Dr. Mike Hanssen, must watch. So what you basically just have to avoid in food is processed foods (can be a lot of things, not all processed foods are necessarily bad), saturated fats from animal meat or eggs, milk etc. Then for a big part refined/added sugars, especially in higher doses like cola etc. And then just 1 more that is pretty known too, fried foods, not necessarily cuz the amount of fat it contains but often unsatured fats are used there & several times again which might create trans fats too, some of the worst. And then it's often combined with like some fat meat & sauce etc. So I don't think any of the natural/vegetal & pure oils are bad, it's more the processed shit or animal fat u gotta avoid. So those pure oils, fats probably indeed don't create any "bad cholesterol". But if U wanna know real risk or how high ur bad cholesterol is gotta look for the LDL type B i believe. And meds like statins are mostly just affecting the harmless part of LDL cholesterol, but it's all in that video I gave :)
@teresacesario6247
@teresacesario6247 Жыл бұрын
I have spent many many hours walking and riding my 3 speed bike just listening to your podcasts, even when I can barely comprehend the science, but I have learned SO much!! Thank you!!
@gabyzoebl2515
@gabyzoebl2515 2 жыл бұрын
This is explanation is great! Would you consider doing more of these short videos (complicated things explained in an understandable way)? Also, I have honestly never been to an MD who makes these distinctions. Thanks for all the great work you are doing.
@mattbhagify
@mattbhagify 2 жыл бұрын
You are helping my family and I so much with this content. Paid subscriber here. Thank you for putting in the hard work. I love the detailed long form discussions as well as these short summaries.
@Healthify360
@Healthify360 2 жыл бұрын
Thank you for this. I am a lay person, I watched many hours of your podcast interviews on this subject and heart disease. Unfortunate the medical terminology is way past my comprehension. I turned it over to my sister who was a nurse to try and sort out what is what. So yes, I would so appreciate you doing more of these type of video's for those of us who are just trying to figure out what to do to stay healthy. I appreciate your content as you seem to take a well balanced view of all the information that is being presented, without having a huge bias. You are my Go To source to trying to find out what the truth is on many health related subjects. Thank you for your time investment to improve our health.
@deeprollingriver52
@deeprollingriver52 Жыл бұрын
All the related women in my family have very high cholesterol. Mine is 350 and my 94 year old aunt’s cholesterol is 480. We have no heart disease, no dementia, and live into our 90’s. For some reason, our cholesterol has a protective affect. My doctor, or my previous doctor wanted to put me on cholesterol lowering medication. I just laughed. Why? Why? He wanted to decrease the very thing that may be keeping me healthy.
@Buorgenhaeren
@Buorgenhaeren Жыл бұрын
Aunty's heart probably look like an uncleaned sewage pipe 😂
@impatientimp3292
@impatientimp3292 Жыл бұрын
In familial hypercholesterolemy the chance for a heart attack or stroke is higher and life long statins are standard. Now we dont know if your aunt is really lucky OR your entire family hasn't had any cardiovascular events in which case maybe u really dont have a reason to take them
@waltpayne9348
@waltpayne9348 Жыл бұрын
Actually, very high total cholesterol is quite common in centarians. That is why total cholesterol is a meaningless marker.
@gmk22799898
@gmk22799898 Жыл бұрын
​@@Buorgenhaeren what would make you think that?
@vickiroberts3469
@vickiroberts3469 Жыл бұрын
Exactly!!!! Statins can cause dementia! Muscle weakness!
@user-fd6pq4uc6k
@user-fd6pq4uc6k 2 жыл бұрын
Great work Peter! As someone who works in biomolecular science, I've been a long time listener to the podcast, however, I like to share easy to follow short videos such as these with friends who may not have the time or interest to listen to 2+hours of in depth biology discussion
@nabilbensaad7636
@nabilbensaad7636 Жыл бұрын
Ily
@Richard-eg6fw
@Richard-eg6fw 2 жыл бұрын
Peter, this is the best video on cholesterol! You’re doing a great public service. God bless you!
@kacykacem
@kacykacem Жыл бұрын
This is honestly the best video/explanation I have ever encountered. Thank you, Doc.
@ericgould1349
@ericgould1349 Жыл бұрын
As always, super well done. I know when I listen to you that I always learn something new. Breaking complex topics into consumable knowledge is an art. Thank you.
@leighnapier4505
@leighnapier4505 6 ай бұрын
We are fearfully and wonderfully made !!
@pfunk2637
@pfunk2637 2 жыл бұрын
Peter - this was excellent! So in summary, measuring apoB (it only costs $20 out of pocket) is a more comprehensive way to look at risk, rather than the individual tests. Please do more of these TLDR topics!
@w1975b
@w1975b 2 жыл бұрын
Research CAC scan/score. edit - it measures CALCIUM buildup/plaque in arteries
@ly5504
@ly5504 2 жыл бұрын
@@w1975b I just did one of these electively at 40 yr old out of curiosity. Gives you piece of mind to know you're not clogged and your diet and lifestyle hasn't been too bad on your cardiovascular system
@w1975b
@w1975b 2 жыл бұрын
@@ly5504 if you're talking about CAC scan, yes, I agree. I had one done a year or two ago and my score was zero, which surprised me. But I'm not complaining! Of course, that's not the only way that people can have a heart attack, just one area to check.
@dorianmichelarmenterossanc668
@dorianmichelarmenterossanc668 2 жыл бұрын
Apo a1/B ratio give u a better u understanding cuz Apo A1 have the HDL fraction into account. Is also cheap
@Gary-ib8dz
@Gary-ib8dz Жыл бұрын
What is TLDR?
@diegocardona9281
@diegocardona9281 2 жыл бұрын
Peter.....this explanation is amazing.I have tried in many ways to explain this to my patients, but this video is what I've found more exactly what it means this topic.!!!!!!
@jackcunningham3401
@jackcunningham3401 2 жыл бұрын
The best summary of anything I have ever seen, ever.
@JustBrowsing777
@JustBrowsing777 Жыл бұрын
Great info nugget on cholesterol. Perfect format, length and the relevant level most people can benefit from understanding enough to make informed decisions when doctors start talking about "bad" or high cholesterol and statins.
@nutritionbyelsa
@nutritionbyelsa Жыл бұрын
I literally always watch a Peter Attia once I finish studying my biochem or physiology even if the video and what I studied aren’t directly connected it keeps me so excited and interested and feeling super smart and badas* that I just study better and learn 10x more and I love it
@suemiller294
@suemiller294 Жыл бұрын
Amazingly easy to follow and make sense. Got popped on a stain at 60 with one set of “ bad labs” after 6 months of junk food ( another story) . No chance to change diet … just Framingham 🤦🏻‍♀️. Lost 40 lbs on keto ( why not on crestor?) now perfect looking labs, trying to convince my doc to update testing after 3 months of Mediterranean & exercise. You’ve given me ammo my fellow Canadian !!!! Love the podcast, you as a guest on others- thanks for all you do !!
@lexitejeda6209
@lexitejeda6209 2 жыл бұрын
I appreciate this video, even though I have listened to or read close to all of your TLDR stuff. Excellent summary. Thank you.
@Dina379
@Dina379 8 ай бұрын
Dear Dr. Attia 😍🥰. I loved your book “Outlive”. Brilliantly written, educational and easy to understand👍 Highly recommend for anyone looking for preventative measures!!! Absolutely love this channel! I didn’t know that you have one… came across it after I read your book. Thank you from the bottom of my heart for all you do ❤❤❤. With love from Vancouver, Canada 🇨🇦
@johnburn872
@johnburn872 5 ай бұрын
You need to do more videos like this. Breaking down basics for people, basic biology. You are so articulate and great at breaking things down. Thank you for this, I am I big fan.
@Pug71
@Pug71 Жыл бұрын
Spot on… Cholesterol is not a problem unless you have excessive inflammation in your arteries. The real problem is insulin resistance resulting in high sugar and high insulin in the blood which causes arterial inflammation. When you have inflamed arteries, then cholesterol can become an issue.
@i.loveyou
@i.loveyou Жыл бұрын
and what cause insullin resistance?hyperlipidemia so
@wilsont1010
@wilsont1010 Жыл бұрын
@@i.loveyou Sugar.
@JD-rc6lq
@JD-rc6lq Жыл бұрын
​@Thebe Kgositsile high triglycerides are caused by liver conversion to fat from carbohydrate as well as inability to dispose of fatty acids due to high insulin (also a result of too much carbohydrate). The result is high LDL dwell time and athrogenic particles.
@headholio
@headholio Жыл бұрын
I don't know of any data that says higher cholesterol does not increase risk if insulin resistance is not present. In fact I'm sure there is plenty of data to show the opposite, so your "only if" statement is wrong.
@wilsont1010
@wilsont1010 Жыл бұрын
@@headholio Insulin resistance leads to more OxLDL, why are we still discussing this subject which has already been 50 years outdated?
@bob-ss4wx
@bob-ss4wx 2 жыл бұрын
One of the best podcasts I've ever about cholesterol! Peter Attia did a superb job by speaking in "English" and keeping it short so we don't get lost in the weeds of medical terminology.
@debra13
@debra13 2 жыл бұрын
I got lost in the weeds! ;-). I don't have any scientific background at all and find him very difficult to understand- I know he has a lot to offer me- someone with diabetes and metabolic issues- but I feel so lost when he speaks. I thought the "ratio" was what was important. On my labs (yes, I guess they don't matter?), my LDL is extremely high, my HDL was decent enough as I recall, my triglycerides were just fine. My ratio of "risk" was not high but cardiologist freaked , especially since I am trying and failing to do LCHF diet. I don't know where to go to find information like Peter's that I can actually understand.
@dieselbourbon3728
@dieselbourbon3728 Жыл бұрын
@@debra13 Short answer. Eat a low to no carb diet. Eat fatty clean meat in ratios your bowels need to operate properly. Stay away from all sugars and processed edibles. Don't worry about cholesterol. Personally I need allot of fat to keep my energy level high enough. Triglycerides have never been lower.
@chi5168
@chi5168 Жыл бұрын
@@debra13 look into Dr. Berg's podcast info. It's fairly simple to grasp.
@fabioq6916
@fabioq6916 Жыл бұрын
@@dieselbourbon3728 none of that is recommended by Attia though so why offer it as a translation of what this video says?
@katherinegill6015
@katherinegill6015 8 ай бұрын
That you for your time and how you tried to explain the “basic” to us all. ❤ really appreciate your video!
@andrelemoine1815
@andrelemoine1815 6 ай бұрын
I cannot thank you enough! For a neophyte, your explanation is worth its weight in gold. Education at it's best.😊
@surfreadjumpsleep
@surfreadjumpsleep 2 жыл бұрын
We are so lucky that Peter is so smart!!
@jeremiash5180
@jeremiash5180 2 жыл бұрын
Thank you for being warrior in this seemingly endless fight! ps. Love that Richard P. Feynman photo in the background. It would be104th birthday for him today, may he rest in peace.
@unalusta3170
@unalusta3170 2 жыл бұрын
I adore the way you explain things. Thank you, thank you, thank you.
@yschuler1
@yschuler1 Жыл бұрын
Good God! That means that most doctors I’ve spoken to don’t understand the basics of lipids and lipoproteins! I’ve heard it countless times described as good LDL versus bad LDL. All I have to say is, thank goodness for you, Peter, for sharing your knowledge. And by the way, I have your book, phenomenal!
@Leitmotif4659
@Leitmotif4659 3 ай бұрын
I would say that Dr. explains in the most understandable way.
@aclassmedicine3306
@aclassmedicine3306 Жыл бұрын
Great to hear such clarity. Like “essential hypertension” this good/bad cholesterol misnomer will take a while to eradicate.
@george5120
@george5120 Жыл бұрын
Great video. First time that I heard this doctor. No splash screens, multimedia, music in the background. Just a quick delivery of what we need to know. My guess is that few physicians have his understanding of lipidology. Most physicians probably just read markers in a Lipid Panel and then prescribe statins based upon ranges printed on the Lipid Panel itself for what is healthy versus unhealthy.
@marysavage6707
@marysavage6707 Жыл бұрын
I just wanted to say thank you for simplifying this so we all can understand it!
@amybee234
@amybee234 Жыл бұрын
such a clear and interesting explanation, thank you! amazing that these resources are free
@crystalnichols7224
@crystalnichols7224 Жыл бұрын
This is literally 101. I learned about this in my intro college biology class as a non science student. I still have the printed copy of the article we read about this topic since I so often heard the terms "good" and "bad" cholesterol.
@CelticDruidess1
@CelticDruidess1 Жыл бұрын
That's really interesting - especially given the fact that the medication that physicians give like ALL seniors/pre-seniors is to get rid of cholesterol which they require to maintain basic life forces.
@jjp007
@jjp007 Жыл бұрын
It doesn’t get rid of it all.
@bobjary9382
@bobjary9382 Жыл бұрын
Yeah ! A true truth seeker , a true scientist and a great teacher . So many whilst entering into the venture with a good heart cannot help evangelising and speaking in certainties leaving the viewer thinking ..yay! I need only do this and I'll be all fixed up ... Really we have suffered at the hands of the food industry , private shareholders, an ignorant and reactionary self serving government and the problems that beset our health must be completely understood to be tackled . Thank you so much for what you're doing.
@musicforaarre
@musicforaarre Жыл бұрын
Wow ! You have such an excellence of explaining these basics in simple enough terms that I understood them. You didn't skip steps of understanding that others often do. The datum that all cholesterols were the same except that the protein covering is different is new 'old' info to me. Thanks for speaking to me, instead of over me. Aarre Peltomaa
@iamjon1986
@iamjon1986 2 жыл бұрын
Thank you for this. Being my moms POA, its difficult to convince her DR i want to get her off the medication. I have her on a healthy diet reversed her diabetes and hashimotos.
@robkoering2702
@robkoering2702 Жыл бұрын
What does her diet consist of?
@p-Claud73
@p-Claud73 11 ай бұрын
So fascinating! Our bodies and the universe is so complex.
@charlotteechols3035
@charlotteechols3035 8 ай бұрын
I always find your talks interesting and accessible. Thanks for producing such great content.
@jaynepower4330
@jaynepower4330 11 ай бұрын
Very clear & essential information thank you 🙏 You have a knack for translating complex medical info into plain English.
@Maria_Serbina
@Maria_Serbina Жыл бұрын
Peter, thank u so much for awesome and easy to understand explanations. Unfortunately lots of doctors wrapped up in the cholesterol BS and as result prescribing lipitor or similar destructive to the body meds where they are not needed.
@HUGEbanks
@HUGEbanks Жыл бұрын
This subject is so confusing to me. My doctor just put me on atorvastatin for my cholesterol. My LDL is double what it “should” be. I hate taking meds and would love to drop this statin. When is a statin needed and why?
@Maria_Serbina
@Maria_Serbina Жыл бұрын
@Matthew Eubanks , you need to look at the hld number and the difference between ldl and hdl. The healthy doffere difference is 10-15. If it s close to 40, then you are pushing it. This number shows your insulin resistance. Avoid statins at any cost. They destroy your body. My mom bis taking them. They create more harm. Find a holistic doctor who understands the power of fasting .
@dan-qe1tb
@dan-qe1tb 8 ай бұрын
The whole video was just explaining biology in a way that was neither overly dumbed down nor overly technical. He hadn't even gotten into statins or the real or imagined negative effects on your health if it's high. Just explaining what cholesterol is. I was prescribed Crestor and it's not due to, "cholesterol BS". It's not "destructive to the body". Those are both conspiracy theories of your own devising. Neither idea will improve your health and you might have a stroke someday if you ignore your lipid panel thinking any criticism of the results, are s a big pharma fear based scam to get people to buy more pharmaceuticals. I'm refusing to take the Crestor because I don't think they had conclusively proven that my LDL was at an objectionable level due to my perception of the tests having been bungled: they hadn't told me to fast or how close to meals I was supposed to have blood drawn. It changes a lot throughout the day. In fact, I have given a bit, to both sides. It's neither a huge health issue for me, nor should it be ignored.
@blueberry11051
@blueberry11051 10 ай бұрын
Although I thought I knew almost everything about cholesterol in great detail, this is an excellent explanation of cholesterol and its circulatory system. Thank you very much, Dr. Attia.
@ohmlat
@ohmlat Жыл бұрын
Amazing explanation. Thank you Dr. Attia!!
@mariehelenegrenier8146
@mariehelenegrenier8146 2 жыл бұрын
Finally a clear info for beginner...you are great. More
@LedByGrace
@LedByGrace 2 ай бұрын
Is God amazing…as I was listening to all this, how amazing / miracle our bodies created by the Lord. Just mind boggling to me. I didn’t understand any of this but what I do get is how wonderfully we were made by the hand of God. Truly amazing.
@fhowland
@fhowland Жыл бұрын
It’s criminal that they don’t teach this in health or biology class !
@hbjeff36
@hbjeff36 2 ай бұрын
Because this wouldnt sell drugs to lower cholesterol, AND cause muscle issues, memory issues, and diabetes/cancer. Its a limitless market
@mtbse789
@mtbse789 Жыл бұрын
Fantastic. Will be looking for the podcast. Thanks.
@ross5547
@ross5547 2 жыл бұрын
Great video! Thanks, very informative.
@joshmcgarry88
@joshmcgarry88 2 жыл бұрын
Hey Peter, great snippet here im actually a type 1 diabetic however im in extremly good health and my diet is really good too, I exercise regulary through runnung and strength and conditioning and have a good control of my sugars, however i have been advised by my doctor after some bloodwork that i may have Familial hypercholesterolaemia. I will be going to see a cardiologist soon, however it would be great to have some questions i might be able to ask him based on the fact that my health in general is so good, any suggestions or insights would be great 👍
@abdelilahbenahmed4350
@abdelilahbenahmed4350 2 жыл бұрын
Thanks for the valuable information. It is interesting to also show how an individual can know if his very high HDL cholesterol level (more than 1,10 gr and up to 1.40 for instance), obtained without any medications, is actually" functional" or" dysfunctional". Waiting for your coming video on this topic, I speculate that this would refer to the "big picture" : if you are not diabetic or insulini-resistant, and all the other parameters of your lipid profile are good, and your inflammation level is very low, and you have no atherosclerosis, THEN your HDL cholesterol could be considered as FUNCTIONAL. Equally important to know what are the factors that contribute to this extremely high but still functional HDL cholesterol : genetics, diet, exercise, fasting ....
@d2row96
@d2row96 2 жыл бұрын
That was an awesome explanation! Thank you!
@marydo3175
@marydo3175 2 жыл бұрын
Thanks! I can't wait for the next videos of thos series.
@sandeeplalka
@sandeeplalka Жыл бұрын
Great information. However, if you would have touched upon the optimum number for each of these - LP(a), APO etc it would have been easier for viewers to correlate things from the traditional method - not saying that individuals assess themselves, but it gives a good understanding to the next level. Over all these years, we have numerically understood what and how much should HDL, LDL, LDLC etc should be. It would help to know the number or ranges for LP(a) and APO etc
@danielmccarthyy
@danielmccarthyy 2 жыл бұрын
Doctors: Your total cholesterol is too high! Doctors: Forget that, now your LDL-C is too high! Doctors: LDL-P is a better measure. Doctors: OK, we need NMR tests to detect small, dense LDL. Doctors: Yikes, your Lp(a) is elevated. Doctors: Actually, we should look at ApoB instead. PATIENT: WTF? Is there a different treatment for each? DOCTORS: No, we'll just give you a statin which doesn't work anyway. PATIENT: WTF???
@Arunkumar-bg5xk
@Arunkumar-bg5xk 2 жыл бұрын
I hear you! I share the same experience... I think the problem the doctor faces is whether or not it is necessary to put you on a statin coz once they do, you're on the pill for the rest of your life....well atleast a good doctor will actually do this.
@danielmccarthyy
@danielmccarthyy 2 жыл бұрын
@@Arunkumar-bg5xk And once you get on the Statin, type two diabetes is just around the corner, and diabetes brings heart disease with it. So obviously this is the wrong approach. Then there are some new medication‘s which have not proven a mortality benefit which will get the patient on the liver transplant list. So it seems the diet and exercise, whatever that might mean for the particular patient, is the only viable way forward
@Arunkumar-bg5xk
@Arunkumar-bg5xk 2 жыл бұрын
@@danielmccarthyy you may already know this Peter Attia's whole approach to longevity focuses on exercise as its centerpiece.
@eswaribalan164
@eswaribalan164 2 жыл бұрын
Cholesterol 'medication' is like the corona virus 'vaccine'.. made by humans to sell for profit.
@Arunkumar-bg5xk
@Arunkumar-bg5xk 2 жыл бұрын
@@eswaribalan164 uh... no
@feedhumans
@feedhumans 2 жыл бұрын
OMG! Thank you so much for this Peter!!!
@skinnyTheCat
@skinnyTheCat Жыл бұрын
Thank you Peter, for sharing your wisdom and knowledge to us all! I just got to say, if this was the absolut most basics of the subject, it makes me understand how smart you are! :)
@Joy80JJ
@Joy80JJ 2 жыл бұрын
This the best explanation on cholesterol. Thank you Peter
@zbLoodlust087
@zbLoodlust087 Жыл бұрын
Confused because on the huberman podcast you said these very things and clarified that dietary cholesterol isn’t correlated to blood cholesterol but saturated fats are in fact correlated to athlersclrosis
@SJQuirke
@SJQuirke 5 ай бұрын
Thank you so much for this clarity Peter Attia MD - I have been reading your work for about a decade and I picked up this message - I did not have the context to ingest the finer detail - but I appreciate your persistence in all of this - Ha! "lower your APOB with these steps" - next watch
@Taureanfitness
@Taureanfitness 7 ай бұрын
Thank you so much for putting this out. It makes perfect sense to me. I worked for a cardiovascular genetic company that did advanced lipid testing, and I'm aware of most of this. But you're even taking it a step further which is fascinating to me. You're also right. Most people do not know what they're talking about when it comes to cholesterol or even Blood Pressure for that matter And the general information. Their reading is totally incorrect and it just confuses them even more
@GenesisReveal
@GenesisReveal 2 жыл бұрын
When someone asks what's your hdl or ldl level, I think it's generally understood that they're talking about hdl or ldl cholesterol. It's just how people talk, trying to avoid big words whenever possible.
@cps_Zen_Run
@cps_Zen_Run 2 жыл бұрын
More specifically, it’s the damaged LDL that causes problems. Damaged LDL cannot be recycled because they no longer fit into the receptacles. Inflammation causes the damage. Refined sugars and excess vegetable oils are inflammatory.
@madhatter9001
@madhatter9001 2 жыл бұрын
How about ALL sugars? Added sugars are killers.
@stellasternchen
@stellasternchen 2 ай бұрын
We have literally antibodies against those removing them from the blood under normal circumstances. Just during arteriosclerosis the antibodies somehow are making it worse. The damaged LDL also are produced by artheriosclerosis, not cause it.
@crispyjeffers
@crispyjeffers 6 ай бұрын
Keep these videos coming! I just finished your book, Outlive, and I loved it. I've been incorporating different aspects of the book into my life, slowly but surely. I have a blood test scheduled with my doctor and am going to request an ApoB level test as part of it.
@kygo
@kygo Жыл бұрын
This is the best explanation of cholesterol I've ever heard, I finally understand what it is now!
@recuerdos2457
@recuerdos2457 Жыл бұрын
Could you give a summary of what he s trying to say??!!… I m actually still confused 🤔
@dorianmichelarmenterossanc668
@dorianmichelarmenterossanc668 2 жыл бұрын
I like ur explanation of Lipoproteins i only disagree in the almost certain assertion abt LDL as “bad actors”. I don’t think the LDL are bad actors per ser (they’re needed for normal healthy processes) they have the potential to be oxidized and then become a troublemaker as u explained before but that doesn’t mean that they will do that or that’s their intended purpose. I just want to point this out cuz people are already under the impression they’re the villains of the movie and that’s not entirely true. Moreover than the amount of LDL-Cholesterol the size / amount of LDL particles are of more importance cuz the small and denser they’re then me more prone the become to oxidation and endothelial infiltration progressing to atheroma and atherosclerosis.
@jemag
@jemag 2 жыл бұрын
Very interesting. I think some added visual support (drawings/diagrams) could help, just a suggestion
@awakening80
@awakening80 Жыл бұрын
Thanks Peter for the TLDR. I enjoy short, to the point videos, that focus on important heakth toplics.
@christinasportiello9542
@christinasportiello9542 3 ай бұрын
Smartest man on the planet. Can’t stop learning from you.
@marybradleyblack
@marybradleyblack Жыл бұрын
My cholesterol is 390. I maintain a good weight, exercise, my triglycerides are good and my glucose is good yet he wants to put me on statins! No effing way am I going to be put on a prescription drug with a ton of side effects that could be detrimental to my health. I mean really?
@debraade706
@debraade706 5 ай бұрын
Good for you my Dr. also wanted me on statins, NO WAY
@chuckbecker8735
@chuckbecker8735 2 жыл бұрын
Watching hundreds of outubes on optimum health for years has cause me to be selective and picky. This channel is creative & unique.
@ballapalleballe
@ballapalleballe Жыл бұрын
Man, best explanation so far. Thanks!
@beardumaw24
@beardumaw24 Жыл бұрын
Great ! Short concise understandable and to the point ! More please.
@marsevar
@marsevar 2 жыл бұрын
Would love to hear a podcast with you and Paul Mason on this subject, especially to clarify if ApoB is a risk itself or only if glycated
@claudiucosar
@claudiucosar 2 жыл бұрын
what i learned is that this particle is bad only if oxidized or glycated which can be due to chronic inflammation, high blood pressure or too many carbs
@richardelson2179
@richardelson2179 2 жыл бұрын
yes please address this question. I currently understand that the ApoB is the point at which the problem occurs and not the cause of problem. So sure. . .more ApoB. . .more opportunity for problems. The cause of the problems is not ApoB but rather glucose spikes which cause glycation followed by oxidation of the ApoB which is guaranteed with high oxidation from diets high in seed oils. Depleted LDL's are normally recycled via the liver. The liver has ApoB receptors to facilitate this. Glycated/Oxidized ApoB's are unrecognizable to the liver, therefore the amount of oxLDL's become elevated. . .and cause problems.
@claudiucosar
@claudiucosar 2 жыл бұрын
@@richardelson2179 what i assembled is that indeed LDL-p tries to protect actually the damaged endothelial cells with the transporting cholesterol however as you point out i'm pretty sure that the fireman is NOT the cause of a fired-building just like the LDL-p in this case. So i would assume that for a healthy endothelium wall that particle was NOT designed and not evolved during 350.000 years such that it produces more harm than good. I struggled most of the time to lower that apoB particles however i don't think that's the approach since i was eating many carbs as well which on the long run can produce glycation which in the end i don't want to end up with since i assume even a "NORMAL" level of apoB with a damaged and inflammed endotelium walls can penetrate and produce deposits/foam...immune responses. from what i learned there are the 2 kinds of damage that a particle can be harmed: oxidation + glycation. so i would assume even in a moderate apoB levels if one has an inflammed wall from a protective perspective the particles would penetrate those cells. true for the last statement as from what i also understood from Peter's long educative lessons however for a non-affected non glycated apoB i don't see any problems. i m using my car on needs, i put gas on it(that could kill me when leaking...) but if everything is in order i can run fine with it....
@sandyglover736
@sandyglover736 2 жыл бұрын
Nobody explains things better than you! 🙌
@Z06GT1
@Z06GT1 2 жыл бұрын
Thank you Dr. Attia!
@mikevaldez7684
@mikevaldez7684 Жыл бұрын
Awesome 👍. This guy has charisma.....loved the talk!
@joetart9905
@joetart9905 2 жыл бұрын
Curious to your thoughts on Lean Mass Hyper Responders... those with really high LDL's and HDL's, but low triglycerides who practice low carb diets?
@johnny7808
@johnny7808 2 жыл бұрын
yeah I want to know too
@caryncook25
@caryncook25 2 жыл бұрын
Me too. I don’t do low carb, but am a faster. Always does a number on my cholesterol.
@phwshopping1426
@phwshopping1426 2 жыл бұрын
This is me!
@VikingHunde
@VikingHunde 2 жыл бұрын
I would pay monthly for just a weekly TLDR from Peter on subjects like this!
@debra13
@debra13 2 жыл бұрын
what is a TLDR?
@VikingHunde
@VikingHunde 2 жыл бұрын
@@debra13 To Long Didn't Read
@700317
@700317 2 жыл бұрын
This is pure gold..
@Rosh_UK
@Rosh_UK 2 жыл бұрын
Loved it. Thank you 🙌
@Jonas_Fox
@Jonas_Fox 2 жыл бұрын
Awesome. I'd love to see one of the animation channels draw out visuals for this to make it dead-simple and more shareable to a wider audience. Thanks Peter for all you do.
@asarcadyn2414
@asarcadyn2414 2 жыл бұрын
Why would an undamaged LDL particle randomly insert itself into the epithelium? And why would it only do it in some arteries and not in veins all over the body? I’m baffled.
@claudiucosar
@claudiucosar 2 жыл бұрын
touche it seems that only the high blood pressure arteries are prone to CVD not the ones with low pressure -returning blood with co2. and even mr thomas dayspring stated that if your endothelium is hard like a castle fence there’s no penetration…
@christopherlogsdon1628
@christopherlogsdon1628 2 жыл бұрын
Peter that was a great explanation thank you so much
@samarthsen4364
@samarthsen4364 6 ай бұрын
Thank you.Excellent Dr as always. I follow yr videos even the lengthy ones.Bought yr book Outlive
@kinwintube
@kinwintube 2 жыл бұрын
This is an excellent explanation. However, I just checked the website of the American Heart Association and they are still talking about good HDL and bad LDL and also that high cholesterol in the diet (red meat) will cause high cholesterol in body??? I suggest you, instead of attacking random people on Internet, you should publicly take on organizations such as the American Heart Association who continues to promote nonsense to the public.
@Seanonyoutube
@Seanonyoutube 2 жыл бұрын
When I cut out red meat my cholesterol came way down 🤷‍♂️
@kinwin2003
@kinwin2003 2 жыл бұрын
@@Seanonyoutube Exactly, that's the whole point of the video. You have been duped into worrying about your cholesterol, while you should really check your apoB, as Peter so elegantly explained.
@Seanonyoutube
@Seanonyoutube 2 жыл бұрын
@@kinwin2003 but whenever my LDL goes down, so does my Apo-B 🤷‍♂️
@w1975b
@w1975b 2 жыл бұрын
Bart Kay is a nutritionist and does response videos. But he portrays a character who cusses as entertainment, and that channel has the most subscribers. His other strictly professional channel doesn't have as many videos or subscribers. If cussing doesn't bother you, I'd suggest checking out the videos to see if any are what you're looking for.
@Thalbouny
@Thalbouny 2 жыл бұрын
Did you just cut red meat or other stuff from ur diet? If you cut out sugar or lower carbs it will also make ur LDL go down. Lowering the inflammation in ur body helps.
@ME-xh5zq
@ME-xh5zq 2 жыл бұрын
Do more TLDR topic intros!
@markmcfadden7428
@markmcfadden7428 Жыл бұрын
Thanks that was very informative. Much appreciated.
@zazzleman
@zazzleman 2 жыл бұрын
Thank you for dumbing this down. If only people explained the stuff like this we would understand.
@debra13
@debra13 2 жыл бұрын
Oh dear, if this is "dumbing it" I am an idiot, and I have 2 Master's ;-). But in English and Social Work. lol
@timmiet47321
@timmiet47321 Жыл бұрын
Great explanation. What is it about the LDL cholesterol molecules that makes them implant themselves into vessel walls? Aren't they made up of the same outer shell which should allow them to flow freely through our vessels?
@director2345
@director2345 Жыл бұрын
Damaged artery needs repair....LDL wants to repair and digs in to patch....then cascade of immune cells pile in to form plaque....If there is no damage to artery, then LDL has no reason to dig in to repair...statins block VLDL in the liver before it even turns to LDL...also blocks COQ10 which is also needed in every cell..
@archstanton9547
@archstanton9547 Жыл бұрын
Good question which is not addressed here as far as I can tell. From what I've read the cholesterol oxidizes and calcifies which is what adheres to the artery walls. I still don't know what causes the oxidation but it could be excess glucose in the blood and so the theory is that high carb diets and not fats cause plaque build up.
@erastvandoren
@erastvandoren Жыл бұрын
Simply too much of it. We can't metabolize cholesterol, we only can get rid of it through cell loss or via making bile acids. Macrophages in the arteries gobble up lipoproteins, but can't process cholesterol, and end up accumulating it. HDL can return some of it to the liver, but if LDL is high, then the accumulation occurs.
@erastvandoren
@erastvandoren Жыл бұрын
@@director2345 This is nonsense.
@timmiet47321
@timmiet47321 Жыл бұрын
@@erastvandoren Not sure I'm buying that. If the vessel walls are not inflamed, any lipids flowing by should not imbed themselves into a vessel.
@KekeLight8
@KekeLight8 Жыл бұрын
OK, from a patient's point of view, what do patients do when the doctor is telling us our bad cholesterol is too high? And More importantly if statements don't really work what do we do?
@mariat.5432
@mariat.5432 2 жыл бұрын
Very informative. Thank you.
@VelocityRE
@VelocityRE 2 ай бұрын
Thank you. I'd listened to the multi-part podcast with you and Dr Lipid, this summary helps
@jasonskeel6474
@jasonskeel6474 2 жыл бұрын
Just my 2 cents here, I think if someone is watching this and able to follow what you are explaining they probably understand what density is.
@pimacanyon6208
@pimacanyon6208 2 жыл бұрын
right. I think you're saying if someone has high density mental capacity they are not going to watch a video like this.
@Oberon44
@Oberon44 11 ай бұрын
seriously, huberman does that too
@ColinMcRaeVIT
@ColinMcRaeVIT 2 жыл бұрын
I really enjoy Peter's efforts, but often after listening to a 2 hour podcast I find myself asking "so what are the actionable items here??". I appreciate the science but as I often can't piece it together sufficiently to actually DO something with it, I., and I think much of the audience, needs more focus on final take-away's. Such as in this case, it would have been good to say "your best bet is to go and test apoB". However this format of a video is great, just that last 1% needed to be "so, go do ____" to get ____ result". Even if non-absolute, with caveats and disclaimers etc., it's still something to "DO" vs. just something to "somewhat understand". :)
@xmazurx
@xmazurx 2 жыл бұрын
He doesn't want to give medical advice because there is a nuance to everything. Just measuring apob is not always enough to determine your risk for cardiovascular disease.
@ColinMcRaeVIT
@ColinMcRaeVIT 2 жыл бұрын
@@xmazurx Yeah I can respect that. It’s kind of a shame that there exists in this culture where everybody hast to make a disclaimer that they’re not giving medical advice. I realize the stems back to the whole litigious nature of American society with all the lawsuits and nonsense but in my perspective if somebody follows advice given by anybody, whether it’s from a KZfaq channel or some blog post, and something bad happens that’s on them as their responsibility to make the choice. Anyway, different subject different discussion I suppose :-)
@erastvandoren
@erastvandoren Жыл бұрын
Plant-based diet, exercise, amla, nattokinase.
@erastvandoren
@erastvandoren Жыл бұрын
@@ColinMcRaeVIT Actually, you will get your monetization cancelled if you give out medical advice. Thank google for that.
@lola.t.6399
@lola.t.6399 Жыл бұрын
@@xmazurx😊
@zarathustraslancet2529
@zarathustraslancet2529 Жыл бұрын
Earned a sub. Thank you for explaining.
@DiegoPereyra
@DiegoPereyra Жыл бұрын
Great educator...! Very cool Dr. Thank you.
@fuze59
@fuze59 2 жыл бұрын
Peter what is your thoughts on taking an extremely low dose statin as cheap insurance? I was going to do this but what concerned me is that statins increase the risk of calcification of the arteries. Is this unfounded?
@Ace_Hunter_lives
@Ace_Hunter_lives 2 жыл бұрын
Generally speaking, arteries don't "calcify" - embedded, pre-existing, soft plaques calcify within the arterial walls. Calcified plaques are actually quite stable and are unquestionably preferable to soft plaques which can rupture and cause massive damage. One of the ways statins help is that they aid in the calcification of soft plaques, thus stabilizing them. However, their ability to do this is considered to be only moderately effective.
@Bbarfo
@Bbarfo 2 жыл бұрын
I quit taking statins about 6 months ago. Been on them for 15 years (20mg) per day. Unfortunately, most physicians in America are a marketing arm for the pharmaceuticals and don't teach good health. Love the Ayrton Senna helmet in the background by the way.
@blanco36
@blanco36 2 жыл бұрын
Did they seem to work well?
@Bbarfo
@Bbarfo 2 жыл бұрын
@@blanco36 The notion of statins being the cure all is now mythical. They are not worth it for most people, but not all. There have been recent clinical trials and studies that are exposing the lack of benefit of statins. Especially when applied to Absolute results versus Relative results. A big difference. Unfortunately, many physicians discover an issue with their patient and immediately refer to a recipe book to see what kind of medication to provide. A big industry for physicians and pharmaceuticals. The word Doctor means "to teach" which does not happen much.
@EvaSawicka
@EvaSawicka 10 ай бұрын
Thank you for sharing your knowledge. ❤
@Rob-bq6ek
@Rob-bq6ek Жыл бұрын
Which tests do you recommend getting in regards to a cholesterol panel and why? And, which lab can we get to give us this information?
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