My mother just passed away from stomach and bone cancer. Very, very painful disease. The only thing that could touch her pain and give her pain free days was Fentanyl. Liquid morphine, Dilaudid or Oxycodone would only bring her pain down to maybe a 7 out of 10. Fentanyl is a very dangerous drug but definitely has a place in modern medicine. I do not know why anyone would choose to do this drug recreationally because it pretty much incapacitates you from doing anything other than laying around, but for a terminally ill patient Fentanyl is a god-send.

I was a heroin/fentanyl addict for 6 or 7 years. I chose to use those drugs. No one forced them on me or coerced me into it. I made a poor decision. Thankfully, I've been off heroin for 2.5 years.

Is this the mf who tripped on those frogs on vice ?

Hamilton Morris is a smart guy who really presents the facts behind substances and doesn't sugar coat shit. Thanks for all the information you've given me on certain substances. Valuable research he's conducted whether you think so or not

When my wife was dying of cancer fentanyl was the pain medicine she used. I put a patch on her shoulder that was 25 micrograms. That was 3 days of medication. I had to use gloves when putting it on her and wash my hands directly after. It was a great drug. Watching someone in their 30’s wish for death from pain is not something I care to repeat.

Rip my boy goth angel sinner

Yeah, I was a heroin addict for a long time. And I use to hate when I got fentanyl. 30 minutes later I was looking for another high. I lost everything from my addiction. Just now getting it back together. 2 years this September 😀

My Dad was on Fentanyl during the last 2 days of his life. He was on it because he had terminal throat cancer. He was hallucinating out of his mind but pain free. It was weird, kind of funny, but it showed how crazy of an opioid it was.

Add Mac Miller as one of the unlucky fentanyl victims. Rip

Fentanyl was introduced for people with extremely high tolerance to opiods for pain management from typically terminal illness. It was never for the average pain paitent

You should do a show about alcohol. I mean it kills like 88,000 people every year in the usa and makes everyone insane, but forget that

I had a surgery recently and I was given a fentanyl straight into bloodstream. Made my head spin after 2 sec and got to experience it for another 3 sec before I went to sleep. Not worth to risk my life for.

Dear Joe. I had Fentanyl patches for back pain. It was wonderful, so much relief so fast. One day while changing my patch, I stuck (stupid) the new patch on the tip of my tongue. Fentanyl must have gotten into my system. My wife tells me she heard a boom in the cellar and came down to find me flat on the floor, blood coming from my forehead which I had bashed falling down face first. When I woke up in hospital, they told me I was technically dead when the ambulance came. I had no blood pressure, no heartbeat and was not breathing. It seems the EMR's revived me after four tries with the defibrillator and assisted breathing. I don't remember a thing besides waking up in the ER with doctors staring at me. In September 2016, I died. Thanks to the EMR's and doctors, I'm back. I will never touch fentanyl again. It is just too dangerous but for some extreme pain, it works wonders, but only in a hospital. Sincerely, The man who died and rose again.

Fentanyl is AMAZING for pain. A few months back I dislocated my shoulder and was in such extreme pain that even just the weight of my own arm would bring me to tears (i have a fairly high pain tolerance so thats really saying something) I was given fentanyl nasally (not sure the doaage, but it worked just like any nose spray) and within minutes my pain was completely gone. I didnt even feel the doctor pop it back into place. If used properly and safely, it can be amazingly helpful for those experiencing extreme pain. On the flip side, its incredibly dangerous if used improperly. Never abuse fentanyl.

rip to my child hood friend who never woke up. it took the rest of us year to realize but we are better now. rip iron pony

I spent many years working in compounding pharmacy and used to prepare fentanyl (as well as sufentanil and carfentanil) in several dosage forms for people afflicted with cancer and other debilitating conditions with severe pain. These molecules absolutely have legitimate medical uses and I have witnessed this first hand in patients and their improvement in quality of life. The problem is with all of the clandestine preparation (e.g. illicit Chinese labs) and ease of access to these compounds in the street through those illicit channels. The general public does not understand just how potent and dangerous these molecules can be and certainly at the tiny amount which can cause an opioid naive individual to overdose.

Hamilton "I know the chemist that introduced Fentanyl in North America" Morris

I've been on fentanyl for 7 years it is not a fun drug to take but being a quadriplegic and in constant pain it does help me feel normal. I know a lot of people that abused it and eventually quit but will no longer be the same. When I started it I realized that I was making a life long decision. The problem is that it was easier to prescribe than pills. Personally I don't think it should be taken outside a hospital because of the risk for abuse

Been smoking fent for about 3 months now , going into rehab today acutally

If Hamilton calls you the weird guy, youre most definitely a weird guy lmao

its essential for cancer pain. That's why its prescribed. I was on the patch and a very safe painkiller. Shoot it up, that's your issue

The road to hell is paved with good intentions

As a senior graduate student in a PhD program in chemistry, the total synthesis of fentanyl is quite simple and extremely cost effective compared to traditional opiate synthesis of morphine or heroin.

Fentynal was dropped in New Orleans in 2009 in the 9th ward and the Bywater area. When I say dropped I mean literally you could find it at bus stops and trash cans laying on the street in it's packaging. It lasted maybe a month in July or August. The first week 14 people in the area died of Heroin laced with Fentynal. I remember this vividly. I lived there. Then it went away only to come back years later as this epidemic.

I recently had fentanyl administered twice in two weeks as part of "Conscious Sedation" during two minor procedures. It's like time travel. I remember the surgeon saying, "Are you ready?", and then asking, "How long is this going to take?" The nurse said, "We're all done." I traveled 45 minutes into the future.

Hamilton is an extremely intelligent and knowledgeable man. I would love to sit down and have a conversation with him someday

In the 2002 Moscow Theater hostage crisis, Russian spetsnaz pumped the theater full of fentanyl gas. The terrorists died but the hostages also died of fentanyl OD. Big oops

please do another podcast with this man

I've been doing prescription fentanyl for about four years now. I started on the 12mg patches, putting them on my tongue, maybe twice a week. Today, I'm doing between 37.5mg to a 50mg patch a day and I am spending about £300 a week buying peoples scripts and I wouldn't wish my addiction on anybody. My doctor says if I don't stop, I'll be dead in 12-18 months if I don't overdose first. This is the first year I've tried to stop and I've relapsed about 8-9 times. I used to think getting off it was the hard part but it's the staying off it, it's the hard part so good luck to anyone trying.

3 years sober almost to the day... Addiction sucks. It can get better. I never thought there could be a day when I would no longer want or crave heroin. Now I don't even think about it. Things can get better. Never give up on yourself. Someone out there loves you and cares about you, even if you haven't found them yet.

I was hooked on fentanyl for 7 years. Living in San Diego by the border it was so easy to get. Thank God I got off of it ; almost killed me so many times.. Today I make motivational uploads to show any addict that its possible to live a normal happy life with out fentanyl #deepinthestreet

I'm always reminded of how lucky I am to have survived my fent addiction, I really should be dead right now

I’ve just been prescribed fentanyl lollies for breakthrough pain and I must say as a pain reliever it’s excellent.

“it’s possible for weed to kill you” *video abruptly ends*

That’s such a great pain killer for cancer patient and hospice patients

Fentanyl in the recreational setting is a nightmare, but as a nurse, I’ve injected some terminally ill patients with it and it works a miracle for them. Fentanyl is sometimes the only things that patients can take that will help with their pain.

It not just the great people we've lost to opiates... Its the regular people and the kids that are left to try to raise themselves.

i went to the university of joe rogan

Hey joe, I was on tramadol for 12 years for a spinal disorder!! Been off them 3 years now, done it by myself as doctors didn’t want me off them!! Hardest thing I ever had to do!! Here in the uk they won’t prescribe my anything else for the pain.... so it’s up super early to get my body ready for work at 6 am!! I really feel for folks hooks on this shit 😔😔 great show pal, listen everyday. Thanks man 👍👍

Same story with Oxy. Was introduced as a “non-addictive” morphine alternative

Fentanyl is an extremely important drug, I'm a paramedic and use this drug regularly. We are able to relieve pain at much less of a dose than morphine, with far less side effects.

I’ve been an opiate addict for over 15 years. Honestly I’ve come to one common understanding over these years. People are going to use and it’s time everyone realizes this. It’s time to make drugs safe to buy and use. To many people are dying. It’s crazy to think a safe dose is behind a counter yet people can’t access it. It all boils down to the money aspect. I can go to a doctor today and get any drugs my heart desires but I have to pay. This whole industry boils down to money and it’s so sad to see people dying when they don’t have to.

I had a fentanyl injection after an operation. Lovely stuff for cutting pain fast. It pretty much knocked me out for a few hours while in the recovery room.

I just had surgery a few months ago and had fentanyl. It was on a button I could only push every 20 minutes. It worked great. I didnt have any withdrawals when i got out of the hospital and really didnt have any pain until i got home.

I had fentanyl laced xanax one time, slept for 18 hours and was sent to the hospital

What if, after the vietnam war, the government saw how passive it made the troops and decided to design a drug that would make the public as passive as possible. To me, that explains the whole situation. I like to refer to firefly and it's take on the reaper virus as explained in serenity. Also, movies like 28 days later and return of the living dead have a good take on this issue.

Fentanyl killed my best friend 3 weeks ago, only 16 years old.

I've been on fentanyl patches for around 12 to 15 years through a pain management clinic. I've had six back of operations. At my worst point I was prescribed all sorts of medication from muscle relaxers to pain pills to depression medication, Etc. Within taking all of this medication I was taking 52 pills a day. That was 18 in the morning 18 and noon and 16 in the evening. I had to be under adult supervision because it was very easy for me to forget that I had already taken my medication and to retake my medication. I was in this stoned state for approximately three years. I have been told that I had done things that I have no recollection of doing and have made so many apologies but behold my family did not accept my apologies. That is something I had to get over. Since then, I have came down tremendously on my medication. I was on 75 mg of fentanyl duragesic patch. My Pain Management Center drop me down to 50 mg and then down to 35 mg which was a 25 mg and a 10 mg patch at the same time. Then I was drop down to 25 mg which I am at presently. I have decided since I am on Percocet, Mobic, Flexeril, which Mobic and flexeril are basically the same being muscle relaxers and also Fentanyl and Xanax. I have decided to try to wean myself off of Fentanyl. I sweat excessively, if I am working outside I would go through 3 shirts soaking wet with sweat in a day's time. I am leaning out with them now trying to get this under control. I have stopped taking my Fentanyl patches for 3 weeks now and I am still going through withdrawals. My stomach stays tore up and I am also trying to fight through the pain. I have been on narcotic medication for approximate 28 years and I am 50 years old so more than half of my life. Everyday that I have been off the patch has been a struggle. My pain management centers stated that if I came out the patch that he would increase my Percocet by two extra tablets per day so that is what I'm going for. I'm taking Percocet, duragesic fentanyl patches, Mobic, Xanax, Etc. I was 90 mme. I am not getting off of fentanyl because of being scared of death but instead I am getting off a bit because every third day I go through withdrawals freezing and sweating at the same time or feeling that my skin is on fire oh, that's the worst feeling. my feet also feel like they are on fire but that is from the neuropathy in my lower legs and feet. I wish that fentanyl was never invented or proscribed. Since I have stopped taking it I've been in bed for 3 weeks now and that really sucks. I do not know if I will continue to stay off the patch because I am in quite a lot of pain without it. people who abuse fentanyl has made it extremely rough for those of us who actually need it

Really interesting guest. Super intelligent speaker. Thanks for having him on

Hamilton Morris is DOPEST dude alive.

Hes right, i was hooked on fent for a while and at night i would wake up every 2-3 hours to do a line...such a sad life

Hamilton is the dude!! Open our ears and listen time to learn!!

I just bought a cat 👍🏼

As a person who was on Fentanyl for years for a chronic pain condition (now on a different opioid). Sadly people don’t see the good, Fentanyl made it possible for me to actually live my life without being stuck in bed hurting and simply not able to do anything. It’s terrible that people abuse it, but the drug does help people. And yes before people ask, or course I have tried weed for pain, sadly it doesn’t work nearly well enough for me to have a noticeable improvement in my quality of life.

Fentanyl is a very useful drug in the clinical setting due to its short DOA

My cousin is a fentanyl addict. He had a great job, a wife, and has a kid. He slowly went down hill and lost everything, and I'm afraid that he's going to die at some point. He's only 25. That's what's so crazy to me. He accomplished so much in a short amount of time, and lost it all, yet, he's still doing it.

To be honest with you I think we need a testimony from a user of both Heroin and Fentanyl “ Artie Lange waddles into room”

I've worked with fentanyl and other high potency drugs in a legal sense, synthesising them for use in medicinal products and the levels of safety in place to prevent workers from being exposed to it is insane, we even have paramedics outside the lab at all times in full haz mat gear ready to rush in with antidote if you are accidentally exposed. To think you can safely use such a drug outside a professional environment is insanely nieve. And while fentanyl is incredibly strong at about 100x stronger than morphine in terms of opioid potency it is still relatively low, things like etorphine and carfentanil blow it out of the water.

Paracelsus - 'Everything is a poison, nothing is a poison. It is the dose that makes the poison'

Kratom saved my life.

Fentanyl is really important on the medical field. A combination of midazolam, fentanyl and propofol is frequently used in most hospitals over here in order to keep the patient sedated during surgery. And it works a lot better with fentanyl than morphine as it takes micrograms of it to knock one out.

Hi Joe- I’m a chronic pain patient that depends on fentanyl in an intrathecal pain pump and in Duragesic fentanyl patches. Fentanyl, along with hydromorphone and oxycodone, helped save my life and it’s an essential part of the medication regimen that allows me to function fairly highly - I am able to rehearse, record, gig and tour with The Dissidents and engineer, mix and produce other bands. The fact that fentanyl is potent but not sedating is fantastic. Opioids help lots of people like myself. To pain patients, opioids are akin to insulin for diabetics. But we’re caught in the crossfire of the crackdown on the “opioid epidemic.” Many pain patients are losing their physicians and insurance companies aren’t covering all or part of our medications. My heart goes out to people who have lost their loved ones to opioids and to addicts who have had their lives wrecked by their prescription opioid abuse. But people who truly need opioid pain medication should not suffer due to the crackdown on opioids. In the national discussion about prescription drug abuse, pain patients also need to have our voices heard - we can give a unique perspective on using opioids for what they are designed. Thanks to Hamilton Morris for a rational, nuanced explanation about fentanyl and other drugs. I love your comedy and podcast, Joe!! Peace Mike Dubose PS: Cannabis is an incredible adjuvant to my medications: it makes the opioids work harder and last longer, has great analgesic properties and helps stimulate my appetite when the pain makes me not want to eat. I wish that I could rely on cannabis alone. Alas, that’s not how my body chemistry works!

I can't imagine being the chemist that introduced fentanyl to the US.

I’m a nurse who works in a nursing home and I can tell you that Fentanyl can work bloody miracles especially in residents who suffer from extreme pain. Of course there will be people out there who suffer from chemical imbalances (depressed, drug addicts) who will pick this choice of drug due to its potency and it will lead to countless broken lives and deaths. If you’re suffering from addiction to drugs, just know it’s completely possible to change your life and turn it around 180 degrees and live the best life you didn’t even know was possible. You’re strong and you can do it.

No David Bowie died of cancer...

Why's Joe asking this guy? All he needed to do is ask Jamie or Eddie. Jamie Aced the study and Eddie has been looking into it.

Anesthesiologists I have talked to have said that its incredibly difficult to titrate the right dosing and keep it metered at a safe dose. They find it highly effective but the ones I have talked to don’t like to use it outside the hospital setting.

Blood pressures good, but I'm getting ringing and small headaches with or without smoke

Transdermal patches of Fentanyl are actually used often in post op for replacement therapy. Short duration, lack of systemic effects (with patch) like respiratory depression, constipation, etc. When its injected it can be very dangerous due to the narrow tx window. Too little? No effects.. Too much? You're dead. Yes, I am a physician. Great clip here.

Rip Peep

Fentanyl allows people with some of the most painful terminals illnesses to die in relative comfort. I know, my friends mother died of stomach cancer last year and one of the nurses told him that only 20 years ago people who had what she had would be screaming in agony. But her death was mercifully free of pain. At least it wasn't so bad it stopped her sleeping. That's the benefit of fentanyl. When you are dealing with the pain of terminal cancer something being 50 times more potent than morphine actually has practical benefits.

Fentanyl is a good medicine. It's just a concentrated medicine. I agree with Hamilton. People who are in really severe pain take opioids like buprenorphine, oxymorphone, hydromorphone, hydrocodone, codeine and fentanyl just to function. These work very well and allow them to get out of bed, go to work, take a shower, pick up things off the floor or even to eat. Have you ever been in so much pain that you couldn't eat or drink? Or breathe? Or move your hand?

I used to main line the gel patches... died twice...quit cold turkey...worst kick ever!!! Clean 5 years now, and I will help anyone strung out that wants to get clean. There are other ways to stay stopped with out a 12 step program. I will never bad mouth AA or NA because I've witnessed many friends get clean through it. But it is not for everyone! Legalize everything too.

He didnt make fent to make money. He made it to lower the price of heroin and make lifes easier for heroin users . . What a statement

Lmfao joe cuts it off right when he starts talking bad about kush 😂

The trouble with any addiction is that when you run out you'll try anything else to get you there. Fentanyl is on another level and it's just so bizarre to read/hear that when folks OD others will rush in to buy what they had taken, it's good for business, yet the dealers kill their clients. Strong alcohol does too, but slower.

Best guest all year

Didn't realize Rogan had so man fentanyl/heroine user fans lol.

Where’s the full vid of this ? I’d like to watch it.

"Weird guy" he says haha love this dude

Gotta add the greatest actor of all time. Phillip Seymour Hoffman. RIP legend.

Bro he might be high asl voice cracks like crazy lol

The Baltimore special to make your grass better👍🏽

Hamilton has a face for radio and a voice for the deaf.

I watched this podcast after watching the one on Kratom they are both very interesting, being that as a teen I was hit head on by a drunk driver which left with me with a laundry list of lifelong issues, one being serious constant pain. My pain management Dr and surgeons agreed a combination of Fentanyl patches and Oxy would be what would work best for me....maybe so. However they had me taking 200mcg Fentanyl transdermal patches to be changed every 48 hours along with up to 13 30mg Oxy tablets PER DAY! I found out someone I had been close friends with ten years previous was found dead with a 15mcg Fentanyl patch in her mouth. I decided I needed to do something different right away. Funny thing was none of the Dr’s who put me on these literally lethal doses of pain meds and kept me on them for over 6 years would help me get off of them. So I did it the hard way by myself. Even using Kratom and trying to wean off slowly I was seriously sick with withdrawals for a year and a half, I’ve never suffered medication withdrawals like that in my entire life nor even when I stopped using illegal substances shortly after the accident. IT WAS HELL. I’m now taking Kratom, yes I’m in a lot of pain but I don’t pry every night when I go to bed that I’ll get to see another tomorrow. Fentanyl should be reserved for only for those who truly need it and will likely NEVER have to suffer going off of it, and most definitely ONLY accept it in the lowest dose possible. I didn’t know any better then, I believed in my Dr’s...now I do my research.

This guy seems vary educated joe you should do another podcast with this guy.

Fentanyl gave my father somewhat of a life with his last years on the planet dying of multiplemyloma bone cancer. I miss him today.

Fentanyl is actually really useful in the medical setting for sedation because of its short acting properties. When someone is intubated and sedated you want something that will wear off quickly so you can easily wake them later to extubate them and get them off the ventilator

My best friend died from a bad cut she left her litttle girl and family behind because a pos dealer and a bad decision. Be safe every one Don’t do drugs You can get help There are people that care

Rip Lil Peep, love that man

Hamilton is a super interesting mfer to listen to

I’m an ER nurse and we use fentanyl all the time for analgesia and sedation....I’ve also had to give more narcan with the OD patients from the medics

Homie just died of this shit. About 2 days ago.

Joe "I've talked with intellectuals' Rogan

This shit almost took me off this earth im so lucky to be a veteran of this plague I have lost so many people to this its crazy please get help if your affected its never to late.

versus morphine your less likely to have an allergic reaction or unwanted side effects, it has a quicker onset with a shorter duration of action, it doesnt supress the respiratory system as much. makes for a great drug for field medicine that's why so many ems systems use it

Hamillton Morris carisma seems like it got a boost thru out the years. I remeber in his vice docs he will look so skinny and so bumbed out. Idk why he seems so changed to me?

Fentanyl is an amazing drug when used appropriately, it has a lot less side effects than other opioids. Not sure if it's the case in the US but in my country ambulances hardly carry morphine at all, it's all been replaced with Fentanyl

Fentanyl does have a very narrow focused purpose. I've seen several friends in the death throws of a horrible cancer find temporary relief and the needed momentary lucidity to say their peace and tell their loved ones that they love them. To help with the kind of pain that cuts you off from the world to live in a solitary box of personal hell is reason enough for it's existence. It's abuse is inconsequential within that context. I cannot think of anything that makes me angrier than when I hear a so called medical professional moralize about prescribing stronger pain killers to a terminal patient. It's an awful thing to say, but any doctor that does deserves to die in that way and be denied similarly. Period.

I knew an anesthetist that used to keep the fentanyl he was supposed to dispose of post op. He was notorious for using balanced narcotic anesthesia (fentanyl/versed) and his patients woke up during surgery pretty often due to being under dosed. He overdosed and died, nobody was surprised. That was in the early 1980’s.