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Lactic Acidosis - Further Thoughts

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CCM TUTORIALS

CCM TUTORIALS

Күн бұрын

This is an opinion piece - a rant if you like about the perceptions and understanding of most healthcare professionals regarding the status of Lactate and Lactic Acidosis.
I am going to make the following points:
Most clinicians overestimate their knowledge of lactate and consider it a waste product of aerobic metabolism
Lactate is likely the end product of glycolysis and a major fuel source for the body
Lactate is always an Arrhenius acid in the body
Lactate is not a good endpoint of resuscitation (“clearance”)
Using Lactate "clearance" as an endpoint usually results in excessive fluid resuscitation
High Lactate and Low Glucose is an Ominous Sign
Nobody can be really sure what is in a bag of Hartmann's Solution (Ringers Lactate)
D-Lactate is likely more harmful than you think
There is no specific treatment for Lactic Acidosis
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