Lecture 6c: Mouse Models

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3 жыл бұрын

UCSD Extension School: Applied Immunology (BIOL-40371)
Summer Quarter 2021
This lecture discusses one of the most important model organisms used for in vivo immunology research: inbred mice. It provides an overview of the differences between transgenic and knockout mice and discusses examples of different disease models and tissue-specific expression systems that are commonly used by immunology basic research labs.
All figures are either from Janeway's Immunobiology (9th ed.) or other publications where noted, or my own original figures.

Пікірлер: 8

@rabitjimmy Жыл бұрын

Hello, I come from Hong Kong University of Science and Technology. I am now working in laboratory animal facility which is breeding the mice you just mentioned in this video. Since I don't have biomedical related degree so I am just a cages changing/cleaning robot there. This video enlightened me and let me know how meaningful my job is.

@mrunmayidalal260 7 ай бұрын

very clear, concise and helpful. thank you Prof. Snyder!

@june-fg7th 6 ай бұрын

Thank you for the lecture. Helped me a lot to cleary understand the mouse model.

@wogus322199 Жыл бұрын

Hi thank you for the lecture! It helped a lot 😊

@songthanh896 Жыл бұрын

Thank you so much!

@thefriulander3595 8 ай бұрын

Hi Annelise... wonderful video.. I finally understand, I think... but I have a question. If you have a mouse model with a floxed gene and a Cre under the K18 promoter... what is the proper control mouse to use? Is it a wildtype mouse? Or a heterozygote mouse that has the Cre under the K18 promoter and an empty LxP cassette? Not sure... please help..