Lineweaver Burk plot

Рет қаралды 350,750

4 жыл бұрын

A typical curve of enzyme kinetics is a plot of a plot of velocity of reaction vs substrate concentration. As the substrate concentration increases the velocity of the reaction increases until it reaches a plateau, which is known as maximum reaction velocity or Vmax. The drawback of this graph is that the plateau region is not perfectly horizontal. Beacuse of this there is a error in the estimation of Vmax and Km. Hence the researchers started modifying the graphs to get better estimate of Vmax and Km. One of such graph is lineweaver burk plot.

Пікірлер: 86

@rachael4775 2 жыл бұрын

I remember watching this in university and I never forgot how helpful it was. Now 4 years later, I'm coming back to it in medical school

@niatai9651 Жыл бұрын

Same!. Except for Pharmacy school

@Lulu-uw1mj Жыл бұрын

the video was posted 2 years ago...

@rakshitasingh6574 Жыл бұрын

@@Lulu-uw1mj 😅

@olaoluwaoyeniyi9948 9 ай бұрын

@@Lulu-uw1mjsarcasm bro

@blueflash3641 4 ай бұрын

hey what was your bsc in ?

@theinkedaaila 4 жыл бұрын

This is perfect to understand whatever the hell is this lineweaver burk plot...... just wow

@Woogie9593 3 жыл бұрын

*watching video after getting all lineweaver burke questions wrong* "hence, lineweaver burke plot is one of the easiest graphs to understand enzyme inhibition"

@alonzojonathan2553 2 жыл бұрын

You probably dont give a shit but does someone know of a trick to log back into an instagram account? I was stupid lost my account password. I would appreciate any assistance you can offer me!

@dustinameer4343 2 жыл бұрын

@Alonzo Jonathan instablaster =)

@alonzojonathan2553 2 жыл бұрын

@Dustin Ameer thanks so much for your reply. I found the site through google and Im in the hacking process now. Looks like it's gonna take quite some time so I will get back to you later when my account password hopefully is recovered.

@alonzojonathan2553 2 жыл бұрын

@Dustin Ameer it did the trick and I finally got access to my account again. I'm so happy! Thanks so much, you really help me out!

@dustinameer4343 2 жыл бұрын

@Alonzo Jonathan you are welcome xD

@BioScienceClass 4 жыл бұрын

More Videos on Lineweaver Burk plot: kzfaq.info/get/bejne/raeHjKx4ubi8gXk.html

@speci4list326 4 жыл бұрын

I was procrastinating because this seemed really hard to understand. Thank you!

@bobmogoboya1477 3 жыл бұрын

Yoh!! im writting tomorrow and i thought i was gonna fail this burk plot and now i get it. Thank you!!!!

@surbhisharma704 3 жыл бұрын

Thank you so much for making it that simple for understanding in a better way

@stellawanjiku4362 3 жыл бұрын

Thanks, this made it so much easier to understand

@jyotsnaraut77 2 жыл бұрын

I thought it's very hard But seeing this video clear all the doubts thank you ❤️

@Drift1 10 ай бұрын

Thank you! the mathematics explanation helped explained how Vmax and Km value changes can be infered from the Line - weever. I guess thats the point of it, make it simple to see changes.

@katejbradshaw 6 ай бұрын

THIS video makes it all clear! THANK YOU!

@nicolevillalon9737 4 ай бұрын

Quick and excellent explanation. Thank you!

@MrCred_ 4 жыл бұрын

I thought this was hard u made it so easy thank u

@itzelhidalgo874 3 жыл бұрын

Fantastic video!! Thank you so much 😉

@ayaahmedmahersayedabdelaal242 3 жыл бұрын

This is so good. thank you!

@heybriaannaa 4 жыл бұрын

great video! thanks for sharing!

@mckenseymiddleton9166 3 жыл бұрын

that helped me a lot, thank you!

@elijahperry3454 3 жыл бұрын

Lifesaver...thanks a bunch!

@peerzadaabrar1800 2 жыл бұрын

Very very Thankful to you. Jazakallahu Khair🤲.

@gayatri5996 2 жыл бұрын

Sometimes the easiest math seem difficult @ 2 o clock at night. Thanks for making it clear!

@logitfau252 3 жыл бұрын

thank u alot :) really helped me for my assignment :)

@mayryelll3822 2 жыл бұрын

the only video that i understood thanks alot 😭🙏

@malithaniman1730 4 жыл бұрын

Helped a lot thanks

@nyikomhlarhimusic 4 ай бұрын

Awesome explanation. Thank you veeeery much 🙏🏿

@AA-kr1ci 2 жыл бұрын

Explained to perfection !

@sanskritimishra7299 3 жыл бұрын

This would help in my presentation ! ✌️

@kamariweaver1536 3 жыл бұрын

What values on the plot are Vmax and what value is Km?

@gatwiringera7567 3 жыл бұрын

thank you very much. Understood!!!!!

@oumaimaboughazala5706 2 жыл бұрын

Thank you so much ,I understand it

@mayryelll3822 2 жыл бұрын

god this was soo easy thank you sm

@jen-hungfang5437 2 жыл бұрын

awesome channel!

@tukurummulkhairi9794 3 жыл бұрын

Thanks a million times

@preethimurugesh6722 3 жыл бұрын

Simply superb

@asiaaaa 2 жыл бұрын

awesome, thank you!!

@harshithjagadeeswaran527 5 ай бұрын

Was really helpful.thanks 😊

@easyochem 2 жыл бұрын

This is a certified hood classic

@tylerdurden7903 4 жыл бұрын

Great video

@MzPeregrine 2 жыл бұрын

You are probably going save my exams today

@rosekendi8590 2 жыл бұрын

Thankyou easy to understand

@abhishekrana5933 2 жыл бұрын

Thank you from 🇮🇳

@linam4848 3 жыл бұрын

Great stuff

@prakritipurushottam8427 3 жыл бұрын

You got 1 subscriber today

@Moye_moye03 9 ай бұрын

Thanks🙏

@user-bq5uw4uy1w 4 ай бұрын

so helpful! I’m an italian med student

@myra9250 2 жыл бұрын

ThankYou.

@ahmedshah6277 2 жыл бұрын

You are not telling about what is meant by these values and how it changes with substrate concentration so its very hard for me to understsnd

@munivet6685 Жыл бұрын

Excellent

@vaishuu04 2 жыл бұрын

Thank you!! It really helped!!!

@emilyi771 Жыл бұрын

@alyssatipler6980 3 жыл бұрын

I dont understand how you get the -1/km as the x intercept

@gfkenya9926 3 жыл бұрын

see below from her post. Best to you. "Nancy Barajas 1 month ago (edited) At the x-intercept, the y-intercept is equal to zero. Using the lineweaver burk equation, you set 1/Vo equal to zero and solve for 1/[S] (x-int). This will give you -1/Km"

@abdullahshah7644 Жыл бұрын

outstanding

@jokebotter-vanelburg8590 3 жыл бұрын

where does -1/Km come from?

@nancybarajas4249 3 жыл бұрын

At the x-intercept, the y-intercept is equal to zero. Using the lineweaver burk equation, you set 1/Vo equal to zero and solve for 1/[S] (x-int). This will give you -1/Km

@JANVI_743 2 жыл бұрын

@@nancybarajas4249 thank you, it was useful

@user-zj7rz5oi9b 2 жыл бұрын

Plz -1/km From where coming???

@prismaticseal2553 3 жыл бұрын

I understand the how, not the why or what are any values

@siddheshpathak9181 3 жыл бұрын

But on X axis why do we take - 1/Km ?

@krutarthshukla3067 3 жыл бұрын

keeps bugging the hell out of me

@paritiyasingh5342 3 жыл бұрын

Since y=0, MX=-c. Then x= -c/m. Substitute values to get. X=-1/Km. Because Vmax get cancelled

@Obamnaz 2 жыл бұрын

@@paritiyasingh5342 Tanksss

@abhi9973 2 жыл бұрын

@@paritiyasingh5342 nice.thx

@tarunkumarpalli7580 2 жыл бұрын

How -1/km is come on negative side of x axis

@AmberU Жыл бұрын

Just maybe I’ll make it through biochemistry

@anchalyadav3061 Жыл бұрын

Thanku

@sebastianlerette9450 Жыл бұрын

🙏

@richardshane456 4 жыл бұрын

Reverse hardware engineering use similar mythology to reverse engineer to find the answer incrementally by best guest trial and error feedback logic a natural humanistic approach to solving a problem with the Mathematical mythology of trial and substitute to understand the trajectory spin of any reaction mathematically incrementally with finer granularity of the understanding of any process... A common mistake with observation by maintaining a relative frame of data points that in reality are trajectory spin... Although the graph inferring to the deduc enzyme reaction metric, belaboring the point of graphical representation for a finite metric that does not disclose the granular processes of the line depicted as the rate of change of velocity. It would be interesting to observe the elementary particle processes of a enzymatic reaction... Ty...very interesting Good day