Lytic and Lysogenic Cycles of Virus Replication

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4 жыл бұрын

Leah4sci.com/virus presents: Lytic and Lysogenic phases of the viral replication cycles
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This video provides an in-depth description of both the lytic and lysogenic phases of the virus replication cycle. You’ll learn how a virus attaches and enters the cell through receptor-mediated endocytosis, as well as how it replicates its viral genome, assembles the viral copies, and ultimately releases from its cellular host. Additionally, this video covers the dormant lysogenic phase in which viral DNA is inserted into cellular DNA and stored until triggered by an outside force.
This is Video #2 in the Viruses Miniseries. Catch the entire MCAT Virus Video Series on my website at leah4sci.com/virus
In this video:
[0:27] Replication cycles of viruses
[1:30] Mechanism of influenza virus
[3:06] Method of Bacteriophage
[5:06] How Retrovirus works
[9:29] Explanation of Herpes
[10:25] Description of Lysogenic Phase
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Пікірлер: 108

@sshredmadalane5342 4 жыл бұрын

Wow I've already covered this on my Microbiology Classes. Thank you So much for making me understand it more

@Leah4sciMCAT 4 жыл бұрын

You're very welcome

@chemiflask7692 Жыл бұрын

Yay! I am so lucky to be able to find this information on your channel! I love it! Thanks

@Leah4sciMCAT Жыл бұрын

You are so welcome, happy to help!

@noicsutak1584 2 жыл бұрын

QUEEN! So easy to understand THANK YOU!👑👑👑💕

@Leah4sciMCAT 2 жыл бұрын

You're so welcome! Glad it helped you understand!

@joshuahauser1969 4 жыл бұрын

Leah, your presentation is excellent. Thanks for the clear (and entertainingly whimsical) information. I look forward to watching your other videos. I do have a question: like many people explaining viruses, you describe the virus using language that suggests the virus has agency. (For example, "attacks", "looking", "push and push", "creating a new membrane around itself", "creates a hole", "simple viruses will self-assemble", "trying to exit", "trying to escape", "finds", "cuts", "if it feels", "forget how to be a virus".) I know it's human nature to do this in explaining things, but should we be thinking of viruses this way? Or is it all "just chemistry" happening in there? How much do we know of what's happening at the chemical level?

@Leah4sciMCAT 4 жыл бұрын

Thanks for the compliments Joshua. Are you asking why I describe the virus as if acting with malicious intent? Perhaps if the virus had a brain it would think 'I am only trying to survive' but since it doesn't I supposed I don't feel guilty making such accusations against it. (you make an interesting point though, good food for thought)

@Sarahsolise 3 жыл бұрын

Wow Leah - what a phenomenal video.

@Leah4sciMCAT 3 жыл бұрын

So glad you like it!

@katherineguzman5752 2 жыл бұрын

lol this was such a good video, I love the delivery bc it helps me stay engaged

@Leah4sciMCAT 2 жыл бұрын

Thanks so much! Glad you liked it!!

@hannahhaggmark1166 Жыл бұрын

This was such a good explanation, thank you!!

@Leah4sciMCAT Жыл бұрын

You're welcome!

@ad7618 8 ай бұрын

Being bilingual is such a blessing, i could make use of this video❤

@Leah4sciMCAT 8 ай бұрын

Glad you've found it useful!

@arwaessameldin4841 3 жыл бұрын

thank you so much, this is so helpful

@Leah4sciMCAT 3 жыл бұрын

Glad it was helpful!

@shivalikabisht1097 2 жыл бұрын

This was extremely helpful. Thank you!

@Leah4sciMCAT 2 жыл бұрын

So glad!

@danadame8330 4 ай бұрын

You have got a new follower. You are the best👍

@Leah4sciMCAT 3 ай бұрын

Thanks so much!

@nawaesuroshebiologyangelof6356 3 жыл бұрын

Really wonderful explanation Thanx

@Leah4sciMCAT 3 жыл бұрын

You are most welcome!

@aqsaibrahim1921 2 жыл бұрын

You explained it in a really easy way

@Leah4sciMCAT 2 жыл бұрын

Glad to help you understand!

@jayasekararathnayaka7087 2 жыл бұрын

Thank you very much Leah

@Leah4sciMCAT 2 жыл бұрын

You are so welcome!

@abmacamv4807 2 жыл бұрын

Thank you so much, you are soooo good at explaining, so expressive👌👌👌👌

@Leah4sciMCAT 2 жыл бұрын

You're welcome 😊

@zeinabtaha3854 3 жыл бұрын

thank you so much for this video

@Leah4sciMCAT 3 жыл бұрын

You're so welcome!

@erickarnez3200 3 жыл бұрын

I came here because I wanted to understand lytic and lysogenic phases, but you exlpained so good and i wanted to know more about coronavirus. I did not find in your website, I hope you will do a video explaining how it works coronavir, because you explain so good. Sorry for my english, I need to practice more.

@Leah4sciMCAT 3 жыл бұрын

You're very welcome, I'm glad you enjoyed the video!

@victoria.cahara4661 Жыл бұрын

Very perfect explanation I must subscribe

@Leah4sciMCAT Жыл бұрын

Thank you so much! I appreciate you watching. :)

@abigailnyashamugadza2878 2 жыл бұрын

Thank you very much

@Leah4sciMCAT 2 жыл бұрын

You are welcome!

@prmft94123 9 ай бұрын

Just surfacing from COVID - thanks for a very clear explanation!

@Leah4sciMCAT 9 ай бұрын

Hope you're feeling fully well soon, and you're so welcome

@ashleyhunter2156 4 жыл бұрын

Thank you

@Leah4sciMCAT 4 жыл бұрын

You're very welcome!

@liammckayproductions Жыл бұрын

Good video that helped me study.

@Leah4sciMCAT Жыл бұрын

So happy to hear it!

@thecasualfront7432 4 жыл бұрын

I love Leah 😍

@Leah4sciMCAT 4 жыл бұрын

thanks?

@thecasualfront7432 4 жыл бұрын

@@Leah4sciMCAT you got me through organic chemistry. And for this, I am quite prepared to marry you.

@Leah4sciMCAT 4 жыл бұрын

I hope you understand but I don't see that as a compliment, I'm already very happily married thank you

@anantkumar3223 3 жыл бұрын

Good explanation

@Leah4sciMCAT 3 жыл бұрын

Thanks so much!

@brittophone6219 2 жыл бұрын

Thank u so much 🥺

@Leah4sciMCAT 2 жыл бұрын

You're welcome!

@braceface813 4 жыл бұрын

Does the retrovirus still follow the transcribe from 5' --> 3' rule?

@Leah4sciMCAT 4 жыл бұрын

If you mean does the DNA synthesis happen the same way as standard DNA synthesis then the answer is yes. The reasoning for this is that the the structure of individual nucleotides requires the polymerase to find an OH group (on the 3' end) where it can grab and attach. Remember, the energy 'cost' for growing the DNA strand is paid for by a phosphate group on the 5' end of the incoming nucleophile

@minabish1783 3 жыл бұрын

Wait, for Corona virus, light symptoms accure befor the 14 days right?

@Leah4sciMCAT 3 жыл бұрын

Since this is a new virus, our understanding is constantly changing as we learn more. Check the CDC for the latest informatin.

@mucahitaltuntas776 Жыл бұрын

excellent

@Leah4sciMCAT Жыл бұрын

Thanks! Glad you like it!

@supriyaanand9904 2 жыл бұрын

yasss thank you so much

@Leah4sciMCAT 2 жыл бұрын

You're very welcome!

@bibigail2707 3 жыл бұрын

What does make virus prefer to replicate through lytic or lysogenic cycle? And which cycle is more dangerous?

@Leah4sciMCAT 3 жыл бұрын

That is an interesting and complicated question that is beyond the scope of this video. Some viruses are capable of reproducing through both cycles, while some prefer one over the other. The preference depends on a variety of factors. As far as “danger”, both of these are means of viral reproduction. The end result is the same, but the means are different. I don’t think we would consider one more “dangerous”.

@tasneemmohammed2315 2 жыл бұрын

Really very useful thanks 🌷 I have exam after 5 hours from now 💛😅 hope me a good luck

@Leah4sciMCAT 2 жыл бұрын

You're welcome and hope your exam turned out well!

@maohammadraza9967 3 жыл бұрын

Thanks mam

@Leah4sciMCAT 3 жыл бұрын

You're welcome

@farinafan7464 6 ай бұрын

Thankuu ❤️

@Leah4sciMCAT 6 ай бұрын

You're very welcome!

@amalmohamed2037 4 жыл бұрын

i dont understand something + strand rna have rna in the 5'--3' so they dont have to carry the RNA dependent RNA polymerase so it can go straight into proteins right? but what about - strand rna??? in my princeton book it says they must carry the RNA dependent RNA polymerase because its in the 3---5' direction but i thought replication always occur in the 5---3' direction?

@genanichols6874 3 жыл бұрын

- sense RNA viruses have to carry their RNA polymerase in the capsid in order to facilitate replication. First the RNA pol will use the negative strand as a template to make positive strands (using the 3'-5' template to make a 5'-3' copy), that will then be used as mRNA. Then the polymerase will use those positive strands to make more negative strands. Yes, replication does happen in a 5'-3' direction, but the -ssRNA viruses only package the equivalent of the DNA coding sequence.

@Leah4sciMCAT 3 жыл бұрын

Everything you have said here is correct. In the replication of the negative-strand RNA virus, RNA polymerase is required to produce a new strand that is oriented in the 5’ -- 3’ direction, but it must “read” (or copy) the RNA in the 3’ -- 5’ direction. Positive-strand RNA viruses, being initially oriented in the 5’ -- 3’ direction, are similar to mRNA in that they can be immediately translated to proteins. This video does not cover RNA virus replication in such detail, but you are absolutely on the right track.

@addicted.z7095 3 жыл бұрын

THANK UUUUUUU

@Leah4sciMCAT 3 жыл бұрын

You are very welcome!

@educationalplateform9468 4 жыл бұрын

26.5/100 how to divide it or any this kind of number quickly mcat point out view

@Leah4sciMCAT 4 жыл бұрын

See my MCAT Math videos leah4sci.com/mcatmath

@mobarkalwahishi3323 3 жыл бұрын

I don't understand something, how the dna of bacteriophage takes over the cell machinary, I mean why the degradation of bacterial dna happens?

@Leah4sciMCAT 3 жыл бұрын

Thanks for watching and asking. The answer to your question is complicated, and a full explanation would be beyond the scope of what I cover in this video. Once the bacteriophage attaches to the membrane and inserts its DNA into the bacteria, it ‘takes over the cell machinery’ by using the cell’s own helper proteins and other resources to replicate the viral DNA as well as to construct proteins that will help build the capsids for newly assembled phages. At a certain point, enough of the new phages exist to trigger lysis of the cell’s membrane.

@poggerssss 2 жыл бұрын

this is epic lol thanks

@Leah4sciMCAT 2 жыл бұрын

you're very welcome!

@bobleclair5665 3 жыл бұрын

There’s herd immunity in a kiss

@Leah4sciMCAT 3 жыл бұрын

lol

@edthoreum7625 2 жыл бұрын

1, temperature change 2.stress 3. Healthy diet 4.mask 5.social distance 6.onion, garlic, ginger soup

@Leah4sciMCAT 2 жыл бұрын

Great tips!

@shahinafroz6771 3 жыл бұрын

Your class is very interesting.But I am a Bangladeshi.So I have less listening power.It would be more useful if what you are saying was written below

@Leah4sciMCAT 3 жыл бұрын

Glad you enjoy it! I understand what you're saying, but at this time that's not an option, sorry. However, you can turn on closed captioning and read along with me, slowing down the speed if that helps.

@shahinafroz6771 3 жыл бұрын

@@Leah4sciMCAT thanks a lot for your guidelines. ☺ I am a student of class twelve. This topic is in our botany book.In which class is this topic taught in your country?? I want to know whether the education in our country is world class.