Hey Matt are there any studies that compare same doses oral vs topical. So like taking .25mg oral and .25mg in spray and which reduces dht the most and which lowers the serum less but at same mg doses

Not all Finasteride are the same

1 mg pill per day- all good... when I want to get it on ,Cialis overpowers it and im good to go no problem

Yeah, was likely as a result of the upregulation man. After some time, things got back to the default level of sex drive and libido. Good luck with your journey as well.

Have you looked into lysine as a mean to decrease DHT?

Hope it was helpful even though not much has changed since the last update.

So it is normal for finasteride users to not have morning wood constantly? Taken it over a week, I can get it up, but it is dead in the morning. I do have some brainfog.. but idk, will probably pass.

Как дела чувак? Ты начал использование дутастерида?

bro do more reaserch on dutasteride because it is blocking dht 1&2 so there is a big part of it not including the hair losse on the top of the head

any Updates bro? Any sides? :)

i m taking fin 1 mg per day form 20 days it gives me a tes pain so should i give up or talk 0.05 mg fin?

Have you had any sides after lowering your doseage?

@@JayTee2000 less sides since micro dosing. i take about a week break every 3 months, def a difference when it comes to sexual side effects. idk how ppl do 1mg/day. that would be crazy

brother m also on 0.5 mg 3x week since few days . is it working for you ?

@@gj8003 2 month has passed did you get any results

@@genshingt7792i started only after hair transplant. I couldn't continue it.took some break due to busy schedule after moth or so. did not see any noticeable difference with my original hair. no sides either. but I think personally for me hair growth is slow process.

I’m doing same dose, 1 month in so far, no sides . Have you had any sides yourself?

@@Suicidebummer88 can I take 1 mg to 2 mg per week and Will I be able to control the hair fall? What is a proper micro dose to be like?

@@Johnny-bv4kg I’ve now recently came off , but I did 1mg on a kinda , Wednesday and Friday . Look into micro dosing also.

@@Suicidebummer88 did you get any result? How you are planning to go into micro dosing? Are you on telegram?

@@Johnny-bv4kg I had to come off them full time right now , there is a regular youtuber (can’t remember his name that explains microdosing well) .

Graft loss with the bulb is pretty impossible, BUT if it occurs, it is normally accompanied by bleeding on the area where graft was placed.

@@letsgethair you never let us down Matt, thank you!!

I am taking 0.125mg a day and i think evem that dose gives me little bit of insomnia.The good thing is my body goes back to normal fast with that dose.I think finasteride is very powerfull drug and 1mg is way too much.I will keep using 0.125mg to see if i can manage to handle it.If not everyday i will use it at least 3 times a week or every other day until it doesnt give me any side effects. After all even 1 dose a week should give you some benefits...

@@beslemetoany sides bro?

On the 1 mg a week - do you take the 1 mg pill on just one day or do you divide the dose up & take it on more than one day a week? I'm kind of in the same boat: 62 with still most of my hair & just light thinning on the front & vertex area. I stated at 1 mg 3x week (MWF) but had sides (brain fog, tendon tightness, low ejaculatory fluid 😬). Now at .5 mg 3x week & most of those sides have gone away. Hair is stable but no signs of re-growth (it's been 4 months now). You have to be careful with this medication - it's really powerful. That must be why Japan has a *.2 mg* tablet for their patients.

If you only experience thinning at 62 I am nto surprised 1 mg a week works for you. You are lucky

Im balding and my hair is greasy af. It depends totally on your scalp and oil production. I need to shampoo my hair every day. For some it is only once a week.

The side effects are highly overblown. Sensationalism gets clicks. Millions of people have been taking it for 20+ years. It would be very obvious if a large percentage of people were getting serious side effects from it.

@@tomcotter4299 yea I don’t think they are highly overblown look at all the negative comments 🍆 head

Serkan Clinic

I personally started with 0.5mg Finasteride every day (first 2 years), and then adjusted to 0.5mg every other day. Most of the time I didn't have any sides on this regimen.

0.5mg . Start with small dose to see how your body react to that

​@@misterbombasticgralakIs there a difference between finasteride 0.5 mg and dutasteride 0.5 mg?

​@@misterbombasticgralakIs there a difference between finasteride 0.5 mg and dutasteride 0.5 mg?

Odds you dht is still elevated in the scalp. You can have low dht systemically and still elevated dht in the scalp. You would be a great candidate for a microdose level of topical fin in a liposomal form.

it kills your libo and your energy gives u this depressed feeling kinda.. you dang near have to take cocaine every day to counter act it

That's a good point. That might explain why some guys say they can't tolerate 0.2mg

You’re assuming that Finasteride causes side effects through DHT suppression and not some other means (like reduced neurosteroids) which may affect dopamine-serotonin-gaba balance. A lower dose could reduce this even if it still inhibits DHT

You still maintaing your hair now?

What is EoD

@@Jacobandersson-xg5dk every other day

What Abt side effects

If you r Norwood 13 you can expect no more hair loss 😂

Talk to your doctor about it

Boost testosterone

2 weeks if it was a minor beard transplant 1000 grafts or less. 3 weeks if it was a major BT like 1500 grafts and more. Avoid receiving head kicks for the first month after BT.

@@letsgethair Thank you man! 🙏

Exact same for me, I've been off 7 weeks and still am not back to normal, mostly the sleep problems are the worst

i hear also from it and i am also depressed so what is a alternative for it

@@jaspergabriels8933 Topical finasteride.

@@tomcotter4299 can't find this in Europe... Or even in Belgium my country?

@@jaspergabriels8933 Really? Odd. It's readily available in the U.S. You can make it yourself using the finasteride tablets. I'm sure there are how-to videos online.

Its is real im experiencing that now cant sleep for 2days lol and depressed

Update?

I started with ru58841 about 2-3 months after I adjusted it. Taking RU now for 5 months

yes

In the long term (after taking it for 1-2 months at least) it wont matter. Tissue binding of Finasteride is 4-5 days. Once you have a decent amount of Fin in your system, it wont matter if your further intake will be 0.5mg ed or 1mg eod in my opinion.

@@letsgethair thank you Matt

update for us bro

The dose could be to low I take 0.5 every day and no sides for me had symptoms of gyno at the start but went away after 2 weeks

He’s talking about this overstimulation. Just watch the video!

Not as big of a difference as when you stop completely for some time.

yeah, I checked the video already some time ago.

So if I take .50mg every other day is ok?

They say you can reduce 1 mg 3 times per week.

Now I try 0.5 mg 3 times per week

@@leanmachine3251 now i want to try 0.5 3 times per week ( or every other day). I think that all depend how aggressive you alopecia and your age. 1 mg per days for same people it's ok. For another people it's a lot. The way it's the customize dose

Reduce to once daily application or ask your doctor for a lower concentration of finasteride. Most topicals are .25% which is actually way more than you need and probably ends up going systemic.

that is similar what I have been taking since the start of 2022. All good man

No dht simply needs to be lower than you genetic threshold For simply it is 90% But for most 70% is enough

@@SebyMiner oh nice!

yes

Hey mate,What was the clinic name that he got his HT done? How many sittings he did? And one more question,I have been facing hair fall issue from the last 4 years,it was on and off though but as the years passed my hair started to thin which was unnoticeable but from the past one year my hair fell a lot and now it is a bit noticeable that my hair is thinning,I want to cure it or have it arrested,what is the solution for this? Are prp and finestrade enough to maintain the density and control the hair fall?

It is also probably less effective and it is easier to just pop a pill

I think you need to get off for a month and then start taking it again

I also quit it after one month, i got psycghological ed from too much reading forums 😂 i had also little sleep disorder and second week of using it my energy levels significantly decreased but it went away in third week. Some of little side effects were reversible for me. I want to jump on again but i am still scared the sh!t out of it 😂 also my morning woods still weak or non exists, i am 21 years old, this is my 45 days without finasteride but decreasing my morning woods may comes from my smoking addiction and poor sleep.

The most noticeable side effects like ED, libido problems, etc tend to appear within 4-6 weeks after starting based on what I observed so far with other guys. I never got those sides. I don't think you can get strong sexual sides out of the sudden after 1-2 years + of taking Finasteride. But I believe that if you go through a phase in your life when you feel down, a bit depressed, or lack motivation for prolonged periods of time, taking 5 AR inhibitory drugs can potentiate these feelings even further. Cycling Finasteride on and off + micro-dosing it, is the way to go for me.

@@pitbullsami8475 I took finasteride 1 time and I had bad sides the plan was to do 1 mg 3x a week so first day I took it was fine next day my wood was up but was weaker so I didn’t take it the day I was supposed too and my wood stayed weak, after 2-3 weeks of not taking the drug went back to normal, but then again had a drop in my woods hardness till after a couple of months I’m finally feeling great again.

@@Iamrjayhd jesus man, just one pill ?

@@pitbullsami8475 yeah bro it fucking sucks, I want to hop on it cause I’m prone to hair loss I’m receding at 25 I’m subconscious about it. But just that pill gave me bad effects so I’m thinking of micro dosing maybe .25 every 3 days but I’m scared ass shit lmao, another things is I want to box professionally and they drug test and I think propecia is banned by wada and vada

You cut it in half yourself with pill cutter

You have to cut them

RU

speak about it with your doctor.

the experiment is over now, as it didnt give me enough additional benefit.

piller cut

Systemic DHT suppression is the same with 0.2mg - 5mg (about 68% - 72%). The problem of higher doses of fin is the accumulation effect in the long run. Plasma half life of finasteride is 6-8 hours. Let's assume it is 6 hours. The Day has 24 hours. If you take 1mg in the morning at 8 am, at 2pm the finasteride concentration in the plasma will be 0.5mg, at 6pm it will be 0.25mg, at midnight it will be 0.125mg, at 6am next day it will be 0.0625mg - which by the way still has about 50% ability to suppress DHT systemically. If you dose 1mg FIN every day for days, weeks, months, you will never give your body to have its DHT levels suppressed less than 50%. Over time it can result in side effects. If you use 0.25mg finasteride, start at 8am in the morning, at 2pm the finasteride concentration in the plasma will be 0.0125mg, at 6pm 0.0625mg (still 50% systemic DHT suppression btw), at midnight it will be roughly 0.03mg and in the morning hours when you wake up it will be 0.01mg - 0.015mg. I think, if you want to avoid hormonal side effects, it makes sense to use finasteride in the morning and ensure that when you are sleeping, you are not trying to maximally inhibit DHT with drugs while your body actually produces the highest amounts of androgens (T levels peaking in the morning hours between 6-8 am). Your body is recovering during sleep so you want to make sure that your DHT goes unsupressed. This will have positive effects on your hormonal balance in the long run in my opinion.

@@letsgethair So if I understood correctly, with 1 mg of finasteride, there will be an overaccumulation that isn't really needed thus leading to negative side effects? Is DHT at its lowest during the night?

​@@letsgethair does finasteride remain in plasma for 4-6 hours and in tissues and scalp for how many days? (for example in a dosage of 0.25mg)? I don't remember which of the two if in the plasma or in the tissues it is not important to lower the DHT that much in order not to meet the sides. A thousand thanks

​@@letsgethair👍🏻

I've been on Fin for 3 years and my hair loss didn't progress at all I'd say.. With addition of a topical anti androgen like kx 826 nearing potential FDA approval in the future or even by adding low dose oral minoxidil I don't think I will even consider shaving my head in the next decade .

@@letsgethair so 10 years maybe?

@@letsgethair be careful with minox. My heart was thumping hard and fast. I’m going to try 2.5% instead of 5%

After a while the libido normalises which means sensitivity is at play

Exactly...that Drake study has to wrong.

كيف لتجنب الأكتئاب اريد طريقة

180cm, 5f 11

I used to take liposomal topical fin. I don't want to take two topicals at two different times as I don't think you can mix RU and liposomal topical Fin as these solutions have a hydroalcoholic vs liposomal base. I think I am close to finding a good risk/reward ratio dose with oral Fin so I will keep taking it. But for all of you who don't want to take oral F at all, a topical F 0.025% is great I think or liposomal Topical F 0.05%. I think I could replace my oral F with either of these two solutions without losing the efficacy achieved with oral F.

@@letsgethair makes sense, thank you for clarification! I’m taking topical now since few months but see no difference frankly.. I felt as if oral three times a week (1mg, as recommended by hair loss show doctors) was better, so I restarted taking it now since one week.. I live in Berlin, German. Where did you buy the Liposomal Finasteride in Europe ? One more comment, I couldn’t find a lab that measures Allopregnanolone in Germany, any idea? I understood it is a metabolite that has a very short life and most labs doesn’t measure it.. I had anxiety back two years ago after taking oral 1mg daily for 6 months but all signs tell me it is random coincidence as symptoms didn’t improve after totally stopping F for a while…

@@letsgethair makes sense, thank you for clarification! I’m taking topical now since few months but see no difference frankly.. I felt as if oral three times a week (1mg, as recommended by hair loss show doctors) was better, so I restarted taking it now since one week.. I live in Berlin, German. Where did you buy the Liposomal Finasteride in Europe ? One more comment, I couldn’t find a lab that measures Allopregnanolone in Germany, any idea? I understood it is a metabolite that has a very short life and most labs doesn’t measure it.. I had anxiety back two years ago after taking oral 1mg daily for 6 months but all signs tell me it is random coincidence as symptoms didn’t improve after totally stopping F for a while…

0.25mg, not 0.05mg

​@@letsgethairbut the 0.05 mg has more scalp suppression? Than 0.25 confuses me? I'm desperately trying to take it but I tried 4 times and it gives me painful dry eyes every time and goes away after 2months of stopping. So so unlucky. Trying to figure out a way to take it as I have had a hair transplant.

@GEHIRN WISSEN The amount that goes systemic should be so tiny that there shouldn't be any side effects at all. Effects would still be good, because it is applied to directly to the place it needs to be...

@GEHIRN WISSEN it's not more potent at a smaller dose. I use it as a topical!! Nothing to barely anything should make it into my body. That's the reason for using a topical in the first place. Otherwise I could just swallow the pill...

This from TOPICAL fin/min??

@@lancer717 yes! But I'm happy to say that the side effects went away after 4 month. No testicle pain anymore. Slowly going up with the dose. At 0.2mg now.

​@@a.d.h.d.9226 check videos on topical fin. From my understanding after a certain dose (very low) its not any different than oral.

I am doing it. 1.25mg a day right now

Update?

Not sure but interestingly they observed something similar in Caserini's study on topical Fin. 0.025% had better DHT scalp suppression than 0.05% and 0.075%. They found 0.025% to have very similar DHT suppression as 0.1%.

@@letsgethair wow , that's amazing actually .

@@letsgethair so it could actually be true , that the SE of finasteride are due to consumption of a higher dose than required ..

I wouldn't say it's a calm feeling its a weak feeling, fin is shutting the lion in man down

@@bobmarley9712 somewhat. I just have less hustle behind the muscle. What was your experience?

@@vincewarren1271 I'm not on fin atm, I'm just balding haha

@@bobmarley9712 I remember that feeling lol

That's kinda strange, as DHT doesn't affect muscle growth.

hey any updates?

@@mil6308 I had stopped to take it but I was loosing a little bit in on one side few hair , it seems for me, but after one month I had bought finasteride and I still take it now so it was a brief moment to stop it, but I am surprised, I have now no problems of libido!

كيف حالك الأن

Sexual or mental side effects ?

@@mohafar3429 ED, Libido related. No "brain fog" or any of that.

@@anonymousyoutuber4136 happy that lower dose gave you relief from that plus some benefits, so interesting that your case of someone being on the “border” and how much dose matters in your case !

@@mohafar3429 Any knowledgeable physician who treats hair loss will tell you that the medication is dose dependent.

@@anonymousyoutuber4136 How are you getting to 0.25mg? Crushing and weighing or splitting Propecia into 4 pieces ?

Depends on which product you choose. I am not sure about their newest addition of RU 58841. I am testing their 0.3% Retinol. I used their minoxidil products in the past and so did many guys I spoke with so all the minoxidil products are legit for sure + topical Finasteride products. I used their topical Dutasteride for 7-8 months in the past but havent noticed any improvements.

@@letsgethair i am looking for Essengen F. What's your take?