Method of the Year 2010: Optogenetics

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Method of the Year 2010: Optogenetics - by Nature Video

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Күн бұрын

This video shows how scientists can control the behaviour of cells simply by switching on a light. The technique, known as optogenetics, is teaching us about everything from how we wake up to how we learn. That's why Nature Methods has named optogenetics as its Method of the Year 2010. Read more at www.nature.com/nmeth/focus/moy2010/index.html

Пікірлер: 105

@waannab 13 жыл бұрын

This is definitely new information for me. Further developments in optogenetics might lead to large improvements in neural science and could improve human life tremendously and it looks like a less invasive way.

@Snobert99 4 жыл бұрын

Does anyone else here think this science can be turned into a weapon to use against humans?

@humptydumpty762 4 жыл бұрын

Yes, after sowing the ground with electroporation....and other steps..

@iriskoh4115 Жыл бұрын

Already.

@NLawson97 Жыл бұрын

I think we’re too late…already been done

@ElectricRootz Жыл бұрын

Yep its called the covid vaccine

@nuala2721 10 ай бұрын

100% Optogenetic's are being used on the world's LED streetlights for SMART cities.

@trevorwilliams6362 10 жыл бұрын

Jahn Laster do you even understand what this means for the future? Not just for muscle rehabilitation, but for recovering from mental illness of all sorts. This is one of the breakthroughs that will revolutionize EVERYTHING!

@bratbabyp9370 4 жыл бұрын

Or controll everyrhing🤔

@Goodpatron 4 жыл бұрын

Yea...and for corrupt Governments to mind-control the masses by exposing their entire population to some "pandemic virus".

@MrOmniFicent 4 жыл бұрын

I literally laughed out loud at 2:58, how rude of them to interrupt that little dude's workout ^.^

@AnonymousPsych 13 жыл бұрын

Utterly mind-blowing! The implications!

@arminf.1195 7 жыл бұрын

where are the Haffie students at?

@alteregoash 13 жыл бұрын

This is easily the most exciting advancement for neuropsychology and neurobiology in years. It's so much cleaner than breeding or surgery and so much more capable of human application (not in the current state of course).

@josephhelms2362 2 жыл бұрын

This really make a lightbulb go off on your head. Literally.

@RamaswamyIyerGanesh 13 жыл бұрын

Amazinf information. Wonderful also. Genetic Engineering, Neurology, Optics, Biology and life science coming together to prove something extraordinary.

@firesnakepodcast 13 жыл бұрын

Applications for military or controlling Alternative Medicine proponents are exciting.

@MonsieurRondu 13 жыл бұрын

This is pretty neat. The part where the heart cells are being stimulated makes me think that perhaps this technology could be applied as an effective treatment of heart disease.

@pinakibhattacharyya7853 5 жыл бұрын

This technology is being used in modern pacemaker devices.

@trevorwilliams6362 10 жыл бұрын

To be apart of a revelation as important as this.. all of the good that will come from this is so immense! To those of you who are against these tests due to a simple fact of who's being the lab rat (or mouse in this circumstance) is incredibly (and not in the good fashion) narrow minded. I, personally, would find it a great honor to be selected to be involved in these studies and be apart of this breakthrough.

@mohamedamrali1993 8 жыл бұрын

+Trevor Williams I am not against per se, but think about it what if you they insert the virus for gene therapy and you end up dying from an immune response. I think this technology is a blessing and we need to be careful with it

@sydney901 5 жыл бұрын

You, in fact, are the narrowminded person in this instance. Upon shallow thought and lack of empathy for more than just human benefit, this seems like a great revelation. One with more of an empathetic or 'woke' brain (more intelligent) would question whether studies using a living being at its disposal, are "worth" it.

@bratbabyp9370 4 жыл бұрын

Ok i have questions: allergy to light and what does that mean? And should i stop drinking algae or not? Yes I'm pale

@greenandroid 13 жыл бұрын

Exciting, but makes me glad I study plants. Maybe it could be used with stomata? e.g. CAM, or the opposite.

@poonjingpoompoom 6 жыл бұрын

Who else is sent here by Haffie?

@Snobert99 4 жыл бұрын

I was actually sent here by a commentor of the video below. kzfaq.info/get/bejne/isqmiqiBlr_OiWQ.html

@Linsforever 13 жыл бұрын

the heart thing is so scary, it could be used as a bioterrorism weapon, switch on the light and you get a heart attack

@bratbabyp9370 4 жыл бұрын

It's happening

@animelover129 11 жыл бұрын

i believe she confirmed that in the video the narrator stated they were able to detect which nerve cells fire when a sleeping mouse wakes 3:53

@goldwarlord 11 жыл бұрын

Does optogenetics only allow for input or also for output? Can we actually measure a neurons firing activity using similar techniques?

@johnnyscher561 7 жыл бұрын

Yes, there are multiple ways to detect neuronal activity. One way is to couple a multielectrode array to the optical fiber to detect orthrodromic spikes.

@thomasciarlariello3228 Жыл бұрын

Pressure of laser light or photoelectric photovoltaic effects?

@gigibelle7465 6 жыл бұрын

One question to the experts here: Would it be possible to manipulate what we consider memory of experiences this way? Just wondering :D

@bratbabyp9370 4 жыл бұрын

@Searchinganswers 10 жыл бұрын

Why can I not find these videos on facebook?

@davidrosas735 4 жыл бұрын

Colombia presente!

@eligraham55 11 жыл бұрын

Wonderful video.

@andreakaraiskaki925 5 жыл бұрын

what is the protein thats being expressed called?

@bobsmithy3103 6 жыл бұрын

This is 8 years old, why have I hardly heard of this being used?

@fontexstudios 6 жыл бұрын

because it's has huge potential, therapeutically and economically viable. So, the ones working on it, or starting the field, do not want a boom of research to happen, otherwise they will get behind, have more competition and lose the opportunity to become notorious/famous and become rich. It's how fucking society works and they are influenced by it, such as these genetic engineered rhodopsin neurons are influenced by light. For sure we do not have halorhodopsin in our amigdala neurons.

@fernando-personalfrugalfin987 2 жыл бұрын

@@fontexstudios you're right! Ever think this is in the vaccines?

@EclipZeMuzik 6 жыл бұрын

dude you're amazing i love this!

@fontexstudios 6 жыл бұрын

Anyone knows what is the technique to use lasers to control the migration of the proliferation? That would have a utility in tissue formation / proliferation of cells in organ scaffolds, etc.

@bratbabyp9370 4 жыл бұрын

But crowd controll

@KravRage 11 жыл бұрын

According to my professor in my neuroscience grad class, no, it does not all for measurement. At least not yet, anyway.

@Guilopes99 9 жыл бұрын

Is this an invasive method? Does the beam just touch the forehead on the mouse, or must the fiber optic cable reach inside the brain?

@ReauSW 8 жыл бұрын

+Guilherme lopes inside

@mohamedamrali1993 8 жыл бұрын

+Guilherme lopes the fiber optic cable has to be close to the brain structure it activates

@Panthers1337 8 жыл бұрын

+Guilherme lopes They have a non-invasive method were the beam simply touches the forehead and penetrates to the brain tissue if you google enough you will find the science articles

@Guilopes99 8 жыл бұрын

Yes D Hilton but you've got to inject the virus inside the brain somehow, like a stereotatic injection. And the beam loses intensity and diverges penetrating the skin, no?

@Panthers1337 8 жыл бұрын

Guilherme lopes Are you interested in forming a hobby research group or study group. I am looking for people who are interested in this field...Have you heard about Radiotrophic Fungus? It is fungus that is sensitive to xrays and nuclear radiation. Perhaps the same genetically modified DNA process could be combined with this fungus to form a similiar process like opotogenetics expect with sensitivity to radio, WiFI, or LTE cell phone networks or xray waves. Do you know if there is any possible way that a virus could be genetically engineered to pass the blood brain barrier and infect the brain issue with out direct injection. Maybe something similar to meningitis.

@jesuslovesyou2270 6 жыл бұрын

Shout out to Haffie!!!

@racehorse87 13 жыл бұрын

Quick to see the potential? The algal proteins were discovered in the 1970s. Optogenetics is a product of the 2000s. Hehe.

@hostar2 13 жыл бұрын

Interesting research, but poor mouse :-)

@TheAIEpiphany 2 жыл бұрын

Sci-fi stuff amazing how far we've come as a species. Now how exactly do you target a specific neuronal population that's what I'm curious about, seems like injecting viruses into a brain is not very localized?

@JorgeGamaliel 10 жыл бұрын

Optogenetics: using light to control the brain. I want to use light in order to be very smart lol :D

@nicoleta498 3 жыл бұрын

Si puo tradure in italiano Grazie

@pianist00315 12 жыл бұрын

really cool~

@neurocapable 11 жыл бұрын

There are viral vectors that target specific neuronal subtypes as well as other specific tissue. It's always the affinity that is the problem. Sometimes there can be as little as 1% infection rates. The question is - could these low infection rates per exposure increase with successive administrations through the food supply? If so, you have a viable bioweapon. Why not just stop their hearts with the infection? Because if they've already taken the poison, you can extort them; light as a weapon.

@bratbabyp9370 4 жыл бұрын

6 yrs later

@brandersbranders5038 4 жыл бұрын

Method of the year for what exactly?. Corona spy program etc?

@babymmune 11 жыл бұрын

Cutting edge stuff

@likemy 13 жыл бұрын

this is hilarious. Though I'm guessing most of these proteins only respond to visible spectrum light, I'm sure it's possible that engineered proteins could respond to, say, radio waves. We could control infected life forms with radio waves (!), perhaps even certain human behaviors

@bratbabyp9370 4 жыл бұрын

Yep

@KemaTheAtheist 11 жыл бұрын

Compared to most stuff you'll find on KZfaq isn't.

@Rampant7990 13 жыл бұрын

@vrazwer She does not have any lisp at all. Never heard an English accent? The only word I think I heard pronounced differently (w/o listening again) was "algae", which is proper there, just as their pronunciation of the word "beta". Probably best not to troll the science and technological vids for you, or English speaking ones ?

@vrazwer 13 жыл бұрын

Interesting, but why do people with lisps get hired to do voice acting?

@bratbabyp9370 4 жыл бұрын

I love ur comment s0 much i t00k a picture of it☺

@Daunmecca 11 жыл бұрын

In simple words..we are doomed

@bratbabyp9370 4 жыл бұрын

Still kicking?

@BOLDYOJI 13 жыл бұрын

Thank god the internet exists,because if this was 50 years ago we would all be sheep buy now

@bratbabyp9370 4 жыл бұрын

It's GOD w a capital G

@satori85 13 жыл бұрын

@Linsforever Ummm, what? I think you are missing a part of this story. It would not work on anybody who has not received the treatment to produce light gated ion channels. Secondly it would be very difficult to penetrate the chest. Third and lastly, people rely on pace makers currently, a device that is susceptible to EMP's. Your overall post was some what bothersome and uneducated but the most glaring problem was the use of "bioterroism".