Karl Deisseroth (Stanford / HHMI): Development of Optogenetics

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Күн бұрын

www.ibiology.org/neuroscience...
Dr. Karl Deisseroth gives a retrospective on the development of optogenetics, a technology that has revolutionized neuroscience. Optogenetics uses pulses of light to alter an animal’s behavior by taking advantage of light-sensitive ion conductance regulators called microbial opsins, which convert a photon of light into an electrical signal. By using genetics to express opsins in particular neurons, scientists can control the activation or suppression of neurons with pulses of light and measure the resulting behavioral changes in an animal.
Speaker Biography:
Karl Deisseroth is Professor of Bioengineering and of Psychiatry and Behavioral Sciences at Stanford University, and a HHMI Investigator. He earned his MD/PhD in neuroscience from Stanford University. His lifelong interest in psychiatry led him to build a world-class laboratory in neuroscience where he developed optogenetics. His lab studies the control and mapping of neural elements in biological organisms, studying both neurophysiology and behavior. For his scientific contributions, Deisseroth was elected to the National Academy of Sciences in 2012, received the Breakthrough Prize in Life Sciences in 2015, and was awarded the Massry Prize in 2016. Learn more about his research here:
web.stanford.edu/group/dlab/in...

Пікірлер: 35

@elizabethjohnson7677 2 жыл бұрын

Somehow, this Grandma understood the outlines of Prof. Deisseroth’s fascinating, important work. Proof that he is a good Teacher, too.

@kingothesea1 2 жыл бұрын

That is absolutely astounding. Literal mind control.

@Adi64717 Жыл бұрын

Such an excellent explanation. He is admirable.

@ksideth 3 жыл бұрын

A fascinating video. Thanks for sharing.

@StayBassd 7 жыл бұрын

Feng Zhang bout to go down as one of the greatest scientists of our time, calling it.

@elizabethjohnson7677 2 жыл бұрын

Somehow, Jennifer Doudna at Cal won THAT Nobel Prize.

@rudolfjanssen7419 4 жыл бұрын

Very interesting: psychiatrie-neurology experience in this field of optogenetics

@TheAIEpiphany 2 жыл бұрын

Amazing method! What is stopping us from using this technique to map out what every part of an arbitrary animal's brain does?

@DanielPonchioFerreira 5 ай бұрын

Excellent work

@DanielSternB 7 жыл бұрын

What a beast...

@668ib72 3 жыл бұрын

Interesting! What about preventative medicine when it comes to the brain. Health checks? Similar to what we do in cardiology. No one complains about getting their blood pressure taken. 1. Preventative medicine for the brain., 2 Implementation of functional imaging to give insight on brain health and functionality. 3. Stop purposely injuring the brain, head injuries, reduce environmental toxins that poison the brain. We intellectually know that a majority of things we do on a daily basis can have significant long term effects on the health of the brain. No one speaks up. It’s a conflict of interest when a psychiatrist and neuroscientist is a football fan or promotes sports that injure the brain like gymnastics and diving. Also because we are not at a point when we can really detect injuries deep in the brain, using a treatment like this you can not be sure if it is addressing symptomatology but injuring other areas in the process similar to pharmaceutical interventions. Still this is very fascinating and exciting information.

@yesarieroksuz6964 3 жыл бұрын

Excellent..

@Photinus1 3 жыл бұрын

Thank you Nice video, nice guy

@Koplinet 11 ай бұрын

You're a genius.

@peterrodinis7634 6 жыл бұрын

Hooked.

@amirlahijani 6 жыл бұрын

Why is Karl showing us his notebook?

@A3racada3ra 3 жыл бұрын

This field is a hot candidate for a Nobel-Prize, so people go nuts about it. However, many people contributed to that field over time and it is difficult to pinpoint the "inventors" of this field. So, I assume it's because there is some childish discussion in the community about who got the idea of Optogenetics first ... and labjournal entries with dates on it are one way to give some additional "proof" ...

@amirlahijani 3 жыл бұрын

@@A3racada3ra I agree 100%

@giocondopsiquiatra8777 Жыл бұрын

@@A3racada3ra agree... also sounded like a narcisist proof.

@zamankhan4504 5 жыл бұрын

I have novel ideas about human derived ChR2 like protein.

@Dr_Sri_Harsha_Guthikonda 4 жыл бұрын

lets discuss

@HiNinqi 3 жыл бұрын

Have you been able to explore these?

@user-lb6oh6yv6w 5 жыл бұрын

thumb upupup up

@WeWhoBelongtoYou 5 жыл бұрын

“Little trafficking motifs” 🔛🔜🔝

@Amazology 6 жыл бұрын

Yikes!

@ntandomkhize9238 4 жыл бұрын

@christinepro Жыл бұрын

I’d rather have a bottle in front of me, than a frontal lobotomy. As long as this doesn’t get into the hands of Dr. Evil.

@brianvandenberg4467 5 жыл бұрын

2:17 “to stimulate neurons”. 2:33 2:55 damn. #HumanTransceiver #HumanAntenna Broadcast Visual images to grandmas smart tv. BRAINinitiative PhDs will help, or we will all die of cancer