I'm sorry to hear that, although any mental health physician worth their weight would inform their patient of the side effects, and they likely do but because of the nature of those consultations the patient may be willing to say yes to anything

Since 12 years ago I am still in love with only 50mg No side effects!

@@yardartistry4121 now I back at 100mg I was having more side effects with 50mg than with 100mg ... And had more anxiety with 50mg, but pristiq change my life. At least my mental state.

It's done the same for me :)

@@yardartistry4121 do you have sexual side effects? Every anti depressant I use effects me sexual

How long till you were able to feel the effects? I'm thinking it's starting to work for me at 5 days @ 50 MG? Thank you

yes, I would be happy to cover this medication. Tolerance should not be an issue, the main thing I caution people on is QTc prolongation at doses over 100 mg/day.

@@ShrinksInSneakers I'm eagerly awaiting the notification!

Hey I have that, did u feel detached from ur emotions and others? Was it pristiq that helped u?

I can see the rational for the combination it will theoretically increase all three neurotransmitters serotonin, norepinephrine, and serotonin. I would usually make sure an adequate dose is reached with one medication for a long enough duration before adding an additional medication. If this has already been done and you are augmenting it's a reasonable combination. There is a high risk for withdrawal syndrome with desvenlafaxine. It also has more norepinephrine activity than venlafaxine, I have a video detailing that information if you are interested. There are no drug interactions with this combo. Hope this helps, if you have not subscribed to the channel please do and spread the word about what we are doing here.

This information mostly comes from animal studies (rats I believe) and clinically I'm not sure how much it translates to effectiveness in the real work setting but Pristiq has much greater affinity for the NET transporter than bupropion. Hope this helps

Pristiq is better to treat anxiety than Wellbutrin in my humble opinion. On Wellbutrin I worried a lot more than on Pristiq 50 mg. To get off pristiq, Prozac can be extremely helpful from what I’ve heard Hope this helps

Try pristiq 50 mg. It is more affective than Effexor xr. It’s not metabolized In the liver either. They are just about the same drug

This is not medical advice, it’s for educational purposes only. Always talk to your doctor prior to making any changes. I’m not aware of any data indicating increased risk of alcohol consumption while taking these medications. Anxiety is an antidepressant impediment. People with comorbid anxiety will have more resistant depression and will be less likely to respond to medication. If a person has had 5 or more trials of medication without remission, medication is unlikely fully control symptoms. This does not mean people should lose hope, but it does mean the expectations of what medication can do has to change. The expectations should shift from achieving remission to, how can I tolerate these symptoms while still living a meaningful life. Being a good psychophramacologist means knowing the limits of medications. With each successive medication failure, the likelihood of the next medication working decreases. If there is true treatment resistance then ECT, pramipexole, and ketamine remain options, with ECT having the best efficacy for depression. I hope this helps, if you haven’t already, please like and subscribe to the channel and spread the word about what we are doing here. We also have daily Instagram content it may be of interest.

Yes ma'am you "impression " is very correct !!! Please be very careful with those unhealthy desires For your own good 👍

I think you are correct I started drinking at night.

Sooooo if you have anxiety and depression....meds won't help that much?

I would say that if you find an antidepressant that you respond to it may help a little . That's strictly my own experience and doesn't necessarily apply to others . @@brittneywelch2186

sexual side effects are still an issue with this medication. Some people have used pristiq off label to treat ADHD, but I tend to stick will medications specifically approved for ADHD. In short yes this medication may help with ADHD and you need to balance the risks and benefits with your doctor

I take ADHD medication and I've been on this a month and I finally feel a bit of the old me has returned and I haven't cried in the morning upon waking like I have for the past year at least! I wish you well 👍🇦🇺

Do you take pristiq combined with your adhd medication? If so , how is it for you? I’m on adderall but my doctor prescribed me pristiq with it. I havent started it yet

Awesome, glad you found a treatment that works for you. If you haven't subscribed to the channel please do and spread the word about what we are doing here.

I would have your doctor monitor your weight. Some people do experience decreased appetite and in some cases it is transient. The hope would be mirtazapine would balance this out but I think talking with your doctor and careful monitoring are essential given your diagnosis. All the best

Mirtazapine usually makes patient gain weight, and the pristiq doesn’t have as strong weight effect, so hopefully it was ok

Depends on the medication and the patient preference. If we are talking about sedating medications like dopamine blockers then dosing it all at night is a better option. I also dose lithium all at night. With SSRIs and SNRIs they can be activating and best taken earlier in the day. Hope this helps. If you haven’t subscribed to the channel please do, and spread the word about what we are doing. We also do daily Instagram posts to reduce stigma and educate about mental health topics

Pristique is better early in the morning

I can't provide direct medical advice so I can only talk about the medications in general. There is always a risk for serotonin syndrome and other complications when combining medications with a similar mechanism of action. I do not see any benefit in combining these two medications together. I prefer to use mono therapy at an adequate dose and for a long enough duration to properly assess effectiveness. Additional advice would be to talk with your doctor before making any changes. If you haven't subscribed to the channel please do, and spread the word about what we are doing here. We are also creating content on a daily basis for instagram check out the page for additional information.

Be on pristiq only!! You won't need anything else I promise to you!😊

Most side effects are transient and do go away over time, I would talk to your doctor if it persists.

You should be feeling well by now But I prefer 50mg Stating on 100mg I think was high But your doctor prescribed based on your medical condition

Give it some time, many medications require 6-12 weeks of continuous use to see the full benefits. I'm glad you had a good outcome. If you haven't subscribed to the channel yet, please do and spread the word about what we are doing here.

@@ShrinksInSneakers SHE IS VERY CORRECT!! I DID FEEL THE DIFFERENCE A SOON AS THE VERY FIRST DAY TOO!! PEOPLE SHOULD TAKE IT AS EARLY AS 6AM OR EARLY MORNING HOURS!

Yes I do love how I didn't have to wait weeks to feel wonderful!! I at times forget or take breaks but a soon as I start again I feel my 50mg pristique works right away!:))

@@yardartistry4121 ya I agree pristiq works right away !

Thank you

The pharmaceutical and medical device industry is constantly making payouts for all types of medications and devices. We talk about the side effects of the medication and present the information. The main concern with the SNRIs is worse withdrawal symptoms, this can be avoided if a proper tapering schedule is monitored by the doctor who prescribed the medication. The people who I see have problems are those who abruptly stop without a plan.

you act like it's a choice- this medication is expensive and commonly prescribed to the disabled. there are obstacles- shortages, shutdowns, etc... @@ShrinksInSneakers

Not right now, I'm hospital based, but may have something in the future like that. I appreciate the support

@@ShrinksInSneakers What about a consultation on any given time you might have time? I believe that your experience in research might be good for a patient like me. Doctors I have seen are not as up to date as you... Could realy really help

It does make sense actually. interestingly, pristiq has a stronger affinity for norepinephrine at the starting doses, so it definitely doesn’t have the same effects as Effexor. There are differences even if minor. That strong norepinephrine effect might be why it works better.

How are you now?

see my reply on the other comment you left

@@ShrinksInSneakers can my psychiatrist subscribe viagra or anything that will help? Kinda sucks pristiq works but messes up my sexual function. I tried about 4 different anti depressant and finally found that desvenlafaxine works best for my depression and social phobia

There seems to be a sweet spot with many medications where the benefits are maximized and side effects are minimized, I would say 50 mg in this case is accurate. Some people do have benefit over 50 mg but it may not be as robust and comes with more risk of side effects. maybe we will do a video on the sweet spot for each medication

@@ShrinksInSneakers very correct!!

Very correct!!! 50mg is a love!!! It works beautifully!!😘❤❤❤

There is nothing called as quick tapper until you are not suffering a lot

That schedule you described sounds reasonable. I expect you will do well. Despite what people say, I have patients who abruptly stop medication and do not experience a withdrawal syndrome, sometimes other comments make it sound like you can never safely stop the medication which is simply not true. It's always a good idea to do an appropraite taper either way

Hope you had better luck than me. I went off against the advice of my dr's. I won't be trying that again. I'm happy to take it for the rest of my life if it helps me be a happy person. And it most definitely does

how’s it going? just started today 🤞🏻

​@@olives2426Haw you feel

This is not a common side effect and not one that I've seen clinically to this point but I also do not use this medication that often. Hope this helps, if you haven't subscribed to the channel please do and spread the word about what we are doing here,

@@ShrinksInSneakers I have an your Insta.

Wellbutrin did that to me just watching a commercial ; something simple would set me off

@@AP-nx6xo I take Wellbutrin now Im still crying for nothing. I wonder if that’s a true side effect???

@@brazilgrl571 it seems to react that way with me. I think medications affect everyone differently .

That’s a fair point, I never understand why these medication names have to be so complicated

@@ShrinksInSneakers please my first time watching your video. I just got this medication today the 1 June 2022. I don't know if I should take it. I'm afraid it damage my body. I went to the doctor because I'm always feeling depressed because of what I'm going through. St times I feel suicidal 🙃 but not all the time. But I didn't like how my doctor was talking to me making it look I'm crazy. People go through things differently at times. I'm frm jamaica 🇯🇲. Do you think I should take them? If yes , can I still drink my natural fruits juice that contained leaf greens, pineapple 🍍 ginger, beetroot, carrot 🥕 lettuce ,string beans etc etc. Please I hope you reply.

The increased side effect profile is part of the tradeoff for a slightly more effective medication. It can be intolerable for some patients and should be addressed on a case-by-case basis. Many side effects are transient, and others can be effectively treated. My hope is that you found a treatment that works for you. Best of luck on your mental health journey, please let me know if I can assist in anyway

@@ShrinksInSneakers well I started prestiq to finally try it and I have gotten better with the depression and I have tons of energy but I shake like tremors and nervousness. Will those side effects go away in time of usage?

@@lindacarol5982 Most side effects will be reduced or go away completely once the receptors adapt to the medication. It's always goo to look at the dose and see if possibly it's too high causing more activation and anxiety. If you haven't subscribed yet please do so and spread the word about what we are doing here. Also check out the instagram page as we are now creating daily content

@@ShrinksInSneakers thank you for responding 🙏 😊. My psychiatrist told me to cut it in half but I'm scared to cut it cause it's time released and she was aware of that. She said well it couldn't hurt you. But I am no longer lying on the couch all day with crippling depression 😪. So, I am going to keep taking them I've been on 50 for 3 weeks and 25 for about 4 or 5 day's now. I was always thinking I don't have a mental illness but it is in my family. My mom is possibly bipolar among much more. But, she's too stubborn to go to a shrink and too stubborn to take meds. She doesn't think she has a mental illness but she said grandma did her mom. Well she has it to and my other family has mental health issues. But, thank goodness my son got placed on Prozac and low dose it's helping him. But, he may need 10 more mgs. We're sensitive to alot of meds it seems