Served at NileRed's party: * chicken wings with plastic gloves hot sauce * toilet paper moonshine * grape soda also made from plastic gloves * diamonds infused soda water * cotton candy made from cotton balls * french fries fried in soap oil

“Is this hot sauce organic?” “It’s handmade.”

I love the way he talks. At any point you have no idea if the sentence is gonna lead into ‘it didnt work at all” or “it worked flawlessly.” Idk how you manage to make chemistry tense.

I love to watch these videos while I sew, because sewing can sometimes be very frustrating but whenever I feel like giving up Nile Red says something like "Well I lost everything I spent a week working on but that's just how it is sometimes. Anyway"

Cashier: "What are you buying so much vanilla sugar for?" Nilered: "Hot Sauce."

"If you could bring one food with you on a desert island, what would it be?" Nilered: "Plastic gloves"

I love how he gets so far into the rabbit hole, that the molecule doesn't even have a name, so he just calls it "molecule 1".

Watching these is fun, but watching these as a chemistry student is even more, because sometimes you'll be like "Hey, I know this reaction, I did it last week".

This man will turn you in to a pop tart if you call him a nerd

I love how chemistry is a nice mix of "this has to be exactly perfect or it won't work" and "just eyeball it dude it'll be fine"

As soon as I had seen the Potassium Permanganate, a big smile came across my face. I work in water treatment and we use it to remove iron and magnesium from the raw water. It's nice to see a familiar chemical for a change lol

This video really shows you how chemistry is just replacing one thing with another thing 30 different times until you can finally get the thing you want out

Imagine Nigel being interviewed at Hot Ones and bringing his own hot sauce from gloves and vanilla.

Lab safety rules: "always use gloves when conducting experiments." Nile: "Oh, ok."

After just two videos, I am thoroughly convinced that chemists are the most patient people in the world.

You seem like a very fun guy to have as a friend. And not just because of the science experiments, those are just bonuses

Nile Red 5 years from now; "I was looking at a lizard, and it occurred to me that since most creatures are just mostly made of water and carbon, I could design my own sentient species"

Now for the final part of the trilogy: *“Turning grape soda into plastic gloves, then turning them into hot sauce”*

Has the confidence in his chemistry to turn gloves into hot sauce but not in his cooking to roast his own peppers 😅

33:45 while the reaction may have failed, I find this part very satisfying, the little particles being deposited tickled my brain in just the right way

"Then I poured it all into a separatory funnel" That should be on some new merch

Nature: "Look, I spend millions of years evolving chili peppers!" Nilered: "Hold my gloves."

Science is so beautiful. It's like "I don't know what to do, but this paper says 'do this' - so I did it, and it worked." I just love this.

40:02 when everything is going perfectly but you still have a 3rd of the video left

Friend: Damn what’s this sauce made of? Nile: gloves and vanilla…… Friend: …

"I'm sweating, I'm covered in sauce, my mouth hurts... and... I- I think this was exactly how it was supposed to end." is a line that makes me laugh more than some phrases that are even *intended* to be jokes

This man is immune to "touch grass", hed probably find a way to make it out of paper

Every time he says “and I turned on the hot plate” my brain says “that’s right, it goes in the square hole”

"It is possible for it to explode in a giant fireball" "So anyways...." Never change Nile, never change

dang now i have a huge respect for hot sause companies, they must buy millions of gloves a year to make hot sauce, then they have to follow this guys instructions for hours on end just to make a few bottles, mad respect to them

I love when those silly little juices change color

When he tasted it, in my mind he was ACTUALLY eating vinyl glove and some vanilla sugar 😭

This is actual fucking alchemy. Imagine a wizard coming to solve your kingdom's hot sauce shortage in exchange for a million pounds of plastic gloves.

"Do we have hot sauce?" Nigel: **slowly holds up box of gloves**

I personally love rewatching your videos. your presentation, personality, the honesty/humor that comes with mistakes and your concise way of explaining.. it revives the HS sophomore year chemist in me 🥹 always excited to see an upload from you!!

Vanillin amine hydrochloride (C8H9NO2 · HCl) can be synthesized through the reaction of vanillin and ammonia, followed by treatment with hydrochloric acid (HCl). The process involves several steps, but overall it is a relatively safe and straightforward procedure. Here's a detailed recipe for producing vanillin amine hydrochloride: 1. Obtain necessary materials: - Vanillin (C8H8O3) - Ammonia solution (NH4OH, 25% w/w) - Hydrochloric acid (HCl, 37% w/w) - Methanol (CH3OH) - Ethyl acetate (C4H8O2) - Two strong, airtight containers with stoppers - Three beakers or round-bottomed flasks of appropriate size (e.g., 250 mL or larger) - Magnetic stirrer and stir bars - Distilled water - Ice - Filter paper and vacuum filtration apparatus - Rotary evaporator or other suitable method for solvent removal 2. Prepare a solution of vanillin in methanol: a. Measure out 50 grams of vanillin and place it in a beaker or round-bottomed flask. b. Add 150 mL of methanol to the beaker or flask, stirring until all the solid has dissolved. c. Attach a magnetic stir bar to the beaker or flask and stir the solution at moderate speed. 3. React vanillin with ammonia: a. Slowly add 50 mL of ammonia solution (25% w/w) to the vanillin-methanol solution while stirring. The mixture will become cloudy and start to release gas as it reacts. b. Continue stirring the mixture for several minutes, allowing the reaction to complete. c. Carefully pour the resulting solution into a second beaker or flask, using filter paper or a separatory funnel to remove any solid residues. 4. Convert vanillin amine to hydrochloride salt: a. Add 50 mL of hydrochloric acid (37% w/w) to the filtered solution, stirring until it has mixed thoroughly. The mixture will become cloudy and may release gas as it reacts. b. Continue stirring for several minutes, allowing the reaction to complete. c. Carefully pour the resulting solution into a third beaker or flask, using filter paper or a separatory funnel to remove any solid residues. 5. Purify vanillin amine hydrochloride: a. Wash the filtered solid with distilled water, stirring until it has dissolved and then filtering again. Repeat this process several times to ensure that all impurities have been removed. b. Carefully remove any residual solvent using a rotary evaporator or other suitable method. c. Dry the purified vanillin amine hydrochloride in an oven at approximately 60°C for several hours, until it has reached constant weight.

I can only imagine the interaction of buying that much vanilla sugar. "So... You own a bakery..?" "I'm making hotsauce." "With vanilla sugar?" "And gloves."

For centuries, alchemists had been trying to turn lead into gold. Little did they know, it wasn't lead that could be turned into gold, it was plastic gloves.

I Just LOVE that his reasoning for this video was "Hmm... they look vaguely similar"

"I transferred it to a smaller beaker....then when all the methanol has evaporated, I transferred it to an even smaller one." The most normal sentence in this channel 😂😂

Random shopper: "do you need all that vanilla sugar?" Nile: "yes im making hot sauce!"

“I’m usually bad at cooking, but I thought that this is so incredibly simple it can’t possibly be bad.” - NileRed, a Chemist, who works with mixing potentially dangerous chemicals in very specific sensitive amounts for a living.

I love how you're phrasing the entire process like you're about to take an angle grinder and a welder and get to work on the molecule until it's kinda the shape you want.

16:49 yes... Dry the liquid.

Nilered needs to start a cooking channel and keep the format exactly the same

My favorite thing an this channel is that every episode feels like it’s going to be clickbait but he delivers *every. single. time.*

2:08 mmm sauerkraut 5:28 meet the sniper 16:50 mad milk 20:59 mad milk 2: electric boogaloo 29:31 icing sugar... yeah... icing sugar... 56:21 mmm caramel

18:44 I love this part idk why 😭

if i had a nickel every time nilered made something edible out of gloves, i’d have 2 nickels, which is not a lot but it’s weird it happened twice

NileRed was so enthralled by the question of whether he _could,_ he never stopped to think if he _should..._

I know you won't see this Nile but this was the COOLEST thing I have ever seen. I was blowned to see how we can actually use organic chemistry like that, it was amazing 🤓

"It's right on that threshhold.... of being completely inedible." LMFAO i love it

I find it fascinating that I can watch an 1 hour video without understanding anything and not be bored

NilesRed: “I’m feeling kinda hungry” *eyes box of PPE menacingly*

bro's gonna make oxygen into a block someday

it’s 1am and i just at a 250g bar of chocolate and i do feel like throwing up so im kinda dizzy and watching this feels like a acid trip

“Damn, this sauce tastes great! How’d you make it?” Nile, sweating: a chef never reveals his recipe

I love how Nile only talks in past tense hypothetical so you never know if an experiment worked until the very end.

Bro took homemade hot sauce to a new level

This is very similar to the experiment I saw in high school. It is the closest I have found. The one I saw collected the gasses separately and tested with flame and glowing splint. Then the experiment was performed again to rejoin the gasses with electricity. The only dissapointment I had was that the pipette tip was put under water, so it isn't clear that water did not get forced back up from the petri dish.

Just a cautious FYI for anyone making their own hot sauce: I didn't see Nile add any vinegar at the end (although there was some in the peppers). Botulonium toxin grows in anerobic environments greater than 4.7pH, and is commonly detected when people improperly preserving things like chopped garlic in oil. I don't imagine this sauce would be particularly safe to consume after a couple of weeks unless refrigerated. Also, be sure to sterilise whatever bottle you use!

Nile: “It was a little cloudy” Me: “let me guess, separator funnel?” Nile: “so I put it in a flask” Me: “hmm, smart, wise move. That’s what I was thinking all along.”

I always imagine some high tech aliens finding nile's channel in the future when humanity is gone and being like "huh, such a determined little creature indeed" and then proceeding to make in 1s by tech mind power what nile took almost a year lol

59:16 ... This is the moment where super villains or super heroes are created.

Nigel: Is supposedly bad at cooking Also Nigel: Can make a full meal from plastic gloves, bars of soap, and toilet paper.

Feel like having a NMR machine is going to be a game changer for this channel.

24:17 “I wasn’t exactly sure how many to get, but I figured 18 was a descent amount.” Classic Nile

He bought 18 packets of vanilla sugar... He's the person from our math problems

It took me sooo long to realise this vid was over an hour long, I painted my gel nails, cooked and ate my dinner all to the soundtrack of Nile doing chemistry magic. Very nice, 10/10 would recommend.

Ingredients 2 roast peppers 1/4 onion 1 garlic clove 1 teaspoon of salt 1 gram of nordihydrocapsaicin If your having trouble with that last ingredient here is a simple guide

What's absolutely hilarious to me is the actual amount of switching stuff from one container to another and stirring that chemistry actually is. We had it right as kids

This was an amazing chemistry vid. Showing the true complexity of the steps necessary

The thing that gets me is. On its own, this title would be deemed clickbaity. But since it's Nile Red you KNOW he is going to deliver 🤣🤣

New drinking game, Take a shot every time Nile says "Separatory funnel" Edit: Drink responsibly

I listened to this while I was doing my project for my science final.

Soon this dude will turn mercury into toothpaste

"Yo, this is some killer Hot sauce! What's your recipe?" "Eh, just Gloves and vanilla. Nothing special"

Nilered: refers to chemicals as their proper chemical names and/or common names, for instance, "Isononanoic acid" and "Jones Reagent" Also Nilered: Spicy molecule.

“Is this hot sauce organic?” “Aren’t we all?”

Hey man I just love your videos. You show how chemistry is actually done unlike any educational system does. As a chemist myself it is extremely satisfying and also helps me learn things outside of my area of expertise, which is not o chem. I worry about you ingesting solutions made using chromium and other toxic catalysts, but assume you know what you are doing.

23:22 fun fact, that's not a coincidence. The natural biosynthesis pathway for capsaicin actually utilizes vanillin. I've always wondered whether it'd be possible to break that pathway and make vanilla-flavoured chillies

*buying vanilla sugar* Cashier: "making ice cream huh" Nile: "no, it's for a hot sauce"

This guy is the🐐 for putting the sponsors at the end of the video

"Feeling vanilla? Use latex gloves to spice things up!"

This man isn't a chemist, he's an alchemist.

"So I got out a beaker and added 50 mils of distilled water. And into this, I shot in all of my goopy liquid." ~Nile Red, 2022

Fun fact: pure capsaicin is used by doctors to kill nerves for various reasons. Nordihydrocapsaicin is only about half the pungency (spiciness) of capsaicin, but it still sits at 9,100,000 on the scoville scale (capsaicin sits at 16,000,000). This probably explains what happened in the stink bomb video immediately following this one.

Vanilla and plastic gloves making hot sauce sounds like a crafting recipe from a random crafts minecraft mod

if there is anything i've learned from this man, it's that chemistry is a lot of haphazardly mixing things, then using fancy instruments to carefully seperate it into different things, over and over and over. it's great

This man has the most undying need to eat plastic gloves, and it’s hella interesting.

You just took away an hour of my life and I was captivated every minute. Keep it up Nigel

Nile attempting big project before: I needed to figure a way out on my own; Nile attempting big project now: Aye, yo ChatGPT.

NileRed at the grocery store must be hilarious. I imagine him getting lube, vanilla packets, and as much drain cleaner as he legally can at the same time

I will never again complain about moon logic recipes in video games when plastic gloves + vanilla = essence of spiciness is a real thing. nile, as ever, you're a man of focus, commitment, and sheer fucking will.

bro actually turned plastic gloves and vanilla into hot sauce. next thing you know, he is runnin' his own restaurant with his homemade foods. mad respect for doin' this and actually succeeding.

Local chemist robs supermarket storage - took 20 pounds of vanilla sugar

Drinking game idea: take a swig of hot sauce every time Nile pours a solution into a separatory funnel.

NileRed: "Honestly, it's pretty good." Also NileRed: "It's like right on that threshold of being completely inedible"

the absolutely massive "GO" button on the machine is hilarious to me

the main thing milered has taught me is that you should trust nothing and that the refreshing cup of clear liquid can kill you