As always Vinay, you clarify all these important topics for us non-medical listeners. Thank you for all you do… you are wonderful. I am a real fan!

Excellent interview. I really enjoyed hearing the perspective from a physician located outside of the US. Keep up the good work, Vinay!!

I’m 40 and just had my first one because my dad died of colon cancer in his 60s. I didn’t even have a polyp and he said see you in three years. I’m like, nah. Maybe ten. If that.

Now THIS is the type of content we need. Love your pontification but not overly so. Would love Ashish Jha do hand to hand with you instead of one sided echo chamber

Vinay. I can understand your slower speech today. THANK YOU!

reasonable people discussion. thanks

51:20 helpful breakdown of risk/benefit from here to end.

I am so glad I found this channel.

Fantastic discussion

Pediatricians get incentives for childhood vaccines.

As a layperson, I get confused by health policy. Vinay has rescued me.

Let's talk about about the research revealing how the process shifts crucial gut flora in the wrong direction, and may not return to its normal state.

Why can’t you do the full bowel clean out before a flex sig? Seems like a good compromise.

*this is so wild; i get my colonoscopies at IKEA!* small world. i only get them bc insurance covers it & it is cheaper than a colonic & a tarot reading, my old routine. fills a day. & one b4. & one or two after. _JC

I disagree with the fact that the USA somehow has artificially elevated their ADR because its a quality metric. You cant artificially find more adenoma polyps! If you're finding more, its because you're doing a better exam and a better job of looking for them

Intention to treat deals with attrition, but including those who recieved the mail but did not call back and did not give informed consent to any participation?

Can you shed some light on why we have to be sedated for colonoscopies in the US?

44:30 re pancreatic cancer screening: circulating tumor cells? PET scan?

I heard you say diet has nothing to do with colon cancer. I disagree.

I am of the age for a colonoscopy. Should I do the traditional or a CT scan or MRI? I also need an ultrasound of my liver. Would these kill more than one bird with one zone? The colonoscopy scares me and I don’t want to be sedated it won’t do it awake.

Who cares about how the doc feels about procedure? Patient is first.

my uncle just found cancer cells in his prostate and dr’s have been taking forever for results. who/what should i point him to for info on recommendations?

The prof's name is Bretthauer (no s). And advise not advice. You should give a link to the paper - KZfaq won't allow links in comments.

What is ADR?

In what journal is this study published?

I hate to say it but it seems to me like this has become a political argument the US. seems to me that it aligns with ideas on covid policy 😂

What is “fit”? I only ask because I had an upper GI done in the hospital and now the doctor is telling me I MUST have a colonoscopy due to being 51 yo with family history of paternal grandmother dying from colon cancer. I have no symptoms.

Dr. Prasad, I would submit that you're at risk of doing more harm than good if you continue to ignore the fact that many people in your audience won't pick up on the fact that you're focusing on screening colonoscopy as opposed to diagnostic colonoscopy. More generally, have you considered using the phrase "evidence-based public health" (since screening falls in the category of secondary prevention, as in "Centers for Disease Control and *Prevention*) rather than "evidence-based medicine" (which sounds like something that should be taught in medical school)? P.S. Power calculations have nothing to do with minimizing the potential for bias from having a non-representive sample.