Here are the key takeaways: Glucose Metabolism: Canola oil doesn't seem to have a negative impact on glucose metabolism. Studies have shown no significant effect on fasting glucose, and some even found improvements in fasting insulin and insulin resistance. Cooking with Canola Oil: Trials have shown that cooking with canola oil doesn't seem to affect glucose metabolism negatively. Even refined canola oil used in substantial amounts didn't show harmful effects. Body Weight: Evidence indicates that canola oil does not induce weight gain. Some studies even reported a reduction in body weight, particularly in participants with type 2 diabetes or when compared to saturated fat-rich foods. However, the effect was small and not entirely convincing. Fatty Liver Disease: In a trial with participants having non-alcoholic fatty liver disease (NAFLD), both olive oil and canola oil improved fatty liver, with over 76% of participants on canola oil reverting to normal liver grading. Inflammation: The video found no compelling evidence showing that canola oil causes inflammation in living humans. Some in vitro assays suggested an increase in oxidation products, but in vivo studies did not support this. Oxidation: Canola oil doesn't seem to cause oxidation in vivo. However, it's advised to avoid very high temperatures like deep frying and to favor sautéing instead. Cancer Risk: Large prospective studies report that people cooking with canola have a lower risk of dying of cancer than those cooking with butter, and not higher than people cooking with olive oil. Comparison to Nuts and Seeds: There's limited data comparing canola oil to unprocessed sources of fat like nuts and seeds. One trial found no significant difference between nuts and a canola oil-enriched cereal in various health metrics. Large Trials: Some famous trials like Lyon and Finger used canola oil as part of their intervention and found benefits like lower risk of cardiovascular outcomes and improvement in cognitive function. Personal Preference: The video emphasizes that personal choice matters. Some may prefer cold-pressed canola oil, while others may choose not to consume it at all. The video encourages asking for evidence from those claiming canola oil is toxic. Funding and Bias: The video also touches on funding sources for the studies, mentioning that out of about two dozen references, five studies had some ties to the industry, but excluding them wouldn't fundamentally change the picture. Conclusion: Most of the evidence seems to point to the safety of canola oil and even some benefits. There are areas of uncertainty, and more specific questions may require further research. The video emphasizes that personal choice and preference are valid and that scientific evidence should guide decisions. The video provides a comprehensive and balanced view of the subject, considering various aspects of canola oil's impact on health, cooking practices, and personal preferences.

I have worked in many restaurants that use deep fryers. They would not change the oil which was heated for 10-12 hours a day, just replenishing use oil absorbed by the food. Only occasionally, the deep fryers would be cleaned out and all the oil replaced. - I don't believe any of the trials you have mentioned in and other videos looked at an oil heated for so long a period of time. I believe the longest heating time mentioned was 18 hours, but I could be wrong. A study looking at 80-120 hours of heated oils would be interesting to see.

Thank u so much for this video. I am sooo sick of the numerous utubers claiming that any oil other than olive oil is poison.

What I like about the channel is that they always give you an overall big picture on the topic, with no cherry-picking.

Severely underrated channel. The sheer depth to which you research these topics is unmatched. Thank you.

Incredible video. Can’t tell you how many videos appear on my social media feed saying that canola oil is poison but with no actual cited studies. We need to get this video out to the masses

Excellent video - thorough, quickly paced, no frills, just pure content and lots of it.

Great video! I have been following your videos for the last two months and have learned a few things. With pulling a lot a sugar out of my diet, 16:8 intermittent fasting, and going vegetarian on most weekdays I have lost 20 lbs., and my gut health seems to be a lot better.

I want to see a study where they feed people deep fried food in canola oil for a few weeks. Do it with fresh oil everytime. This study is probably the most important because it studies one of the most common cooking methods. I suspect the sheer amount of oil that you ger from processed food and deep frying is the poison.

The "influencers" telling us about poisonous seed oils have the advantage of dramatic soundbytes, so thanks for another measured response that has already gotten a comment about being too long! You always give a summary, so this is a non-issue.

As always, great content presented in an easy to understand format for the average person. I'm so glad your channel is finally getting the attention it deserves.

I really appreciate that you took the time to make a concise long form and detailed video on this subject. Understanding the facts via study and trials is important. Excellent video, and I’d watch any longer deep dive video you do on things like this in the future.

Thank you for the amazing work you do. Appreciate the depth and clarity of the data you provide.

Thank you so much for clearing up confusion on this. As always you are very clear, methodical, and thorough! I love how you embrace the science and cut through the hype! Muito Obrigado!

I just came across your videos, and the quality of the content of your videos is the best I’ve seen. Your fact and evidence based approach deserves more attention and subs. Really helpful. So thanks!

I certainly appreciate all the research and effort that goes into producing your videos. Additionally, I very much enjoy your presentation. The pace and the positive, friendly attitude are very pleasant. Thank you.

I really appreciate your scientific approach to the topics you are discussing in your videos. There are too many alarmists and clickbait videos out there claiming one thing or another.

Thanks once again for a considered, coherent and digestible summary of the available scientific evidence in this area.

As someone who is trained in the scientific method (social sciences), I've very much appreciated your presentational mix of approachable engagement with intellectual rigor, all wrapped up with an impressive syncretic ability. As for the particulars of this video, the risk/benefit profile of canola oil, it's reassuring to hear that my use of canola is, well, benign. If there's a specific set of videos on this channel that are my favorites, it's those explaining, via exposition and visual means, and in conversation (with Tom Dayspriing, for example) the function and importance of ApoB in determining atherosclerosis risk (and what can be done to reduce it). No personal physician nor cardiologist had ever discussed the role of ApoB with me. (I had a quintuple bypass 22 years ago). As a 70 year old who admittedly hasn't culled all the comments, I do have a question/request: Is there a point where you might cover the extant and ongoing randomized controlled trials around senolytics? I believe it might well be of interest to a subset of your viewers, beyond my personal and emerging interest in the topic. Thanks.

Thank you for another amazing video. You and your team have proven your integrity so many times. I kind of wish you would also make money for all your hard work.

Thanks for making these videos. I've been happily using Canola oil for years and then suddenly started hearing about how "toxic" canola oil and other seed oils are. I was always skeptical of these types of comments but at some point I did wonder if there's some truth to it. This video is a good reminder to always ask/look for evidence, especially for such extreme assertions 🙂

Your channel deserves more popularity. Very professional, objective, based on research and opinions of the best experts! But from what I see, nutrition channels run by incompetent people, or even charlatans who lie on purpose, are more popular because people want to believe that most experts and doctors are wrong, that they are corrupt and that only they, thanks to their guru, learned the truth and are someone special.

One of my favorite videos that you’ve made so far! Great stuff

I'd love to see a similar take on soybean oil.

Commenting for the algorithm. This channel deserves a lot more views.

You are a god send, Mr Carvalho. Thanks for compiling the info and making the video.

Amazing video, really enjoy your videos!

Would it be possible for you to address possible health risks of canola and seed oils other than cardiovascular and inflammation? Especially their possible effects on the brain (cognitive function, memory, clarity), perhaps other organs, and any other possibilities? I'm wondering if the way they are processed (deodorizers and other chemical processes) renders them a health risk.

All this is good to know. I bought into the narrative about seed oils and canola oil being inflammatory and unhealthy. I guess I'll go back to using canola. I like olive oil, but it's expensive to rely on for cooking. My subjective impression is olive oil tastes better than canola. Other than that, there's no obvious advantage one to the other.

So grateful for your work! So thorough researched and clearly explained.

Just wanted to say thank you for all the hard work.

This channel is so damn underrated!!!! Regardless of the topic, you handle it carefully without any bias. You rock!

Love your content. This is amazing. Thanks!

Love your content. It is easy to follow and seems quite thorough. I have certainly made some adjustments in my oil consumption over the past 3 years. When I first went plant based, I refused to consume any oil based on the teachings of several well know plant based influencers, which irritated my wife significantly. Now I will use, in small amounts, olive, canola, and avocado oils. Certainly makes some things taste much better.

Fantastic video on a fantastic channel. Thank you for all your hard work!

Thankyou for giving a full list of references. Great summary

Here's my summary of this video with timestamps: 00:00 This video will examine the health effects of consuming canola oil by looking at a wide range of scientific evidence. 00:53 This channel is independent with no sponsorship from any canola or seed oil entities. 01:19 Canola oil slightly lowered LDL-cholesterol compared to olive oil, but both had similar cardiovascular risk metrics. 02:15 Compared to sunflower seed oil and saturated fats, canola oil had lower LDL-cholesterol and ApoB levels. 03:13 No clear superiority of canola oil was observed when compared to other unsaturated vegetable oils. 03:38 Most trials don't specify if they used cold pressed or refined canola oil. 04:06 Refined canola oil retained lipid-lowering properties. 04:34 Some trials tested canola oil's effect when heated, showing reduced LDL cholesterol and ApoB levels. 06:13 Long-term observational studies suggested those cooking with canola oil had a lower risk of cardiovascular death compared to butter users. 07:11 Canola oil showed no significant effect on glucose metabolism metrics when compared to other oils and fats. 08:07 Caloric intake and weight loss can impact glucose metabolism more than the type of fat consumed. 09:04 Refined canola oil did not negatively affect glucose metabolism, even in large amounts. 10:43 Long-term observational studies suggested no increased risk of type 2 diabetes from cooking with canola oil. 11:10 Current evidence suggests canola oil is not problematic for glucose metabolism, but more long-term studies are needed. 11:40 The video references around two dozen scientific studies; five of which have some connection to the canola or vegetable oil industry. 12:35 Funding source shouldn't discredit scientific studies; it's essential to evaluate all evidence based on scientific merit. 13:03 A meta-analysis of 23 studies found canola oil reduced body weight slightly, especially when compared to saturated fat-rich foods. However, most individual trials did not show significant differences. 14:23 Despite some studies showing a reduction in body weight with canola oil consumption, there were no significant differences in BMI, waist circumference, or body fat. 14:48 Canola oil doesn't seem particularly fattening when compared with other oils in terms of satiety. 15:33 There's no significant change in body weight when cooking with canola oil, as observed in certain trials. 17:06 The discussion is about pure canola oil, not processed foods that contain canola oil as one of many ingredients. 18:02 Regarding inflammation, a meta-analysis found no significant difference in inflammation markers when comparing canola oil to other oils like olive or sunflower seed oil. 19:22 Many are concerned about linoleic acid in seed oils leading to inflammation, but long-term data indicates people consuming more linoleic acid tend to have lower inflammation markers. 20:45 Studies investigating oxidation markers in individuals consuming canola oil found no significant differences, even when canola oil is used for cooking. 21:13 HNE, a product of lipid oxidation, was undetectable in unheated canola and remained low even after prolonged heat exposure. 22:03 Canola oil's Vitamin E content, which can inhibit oxidation, is relatively high. 23:26 - In vitro test results sometimes differ from in vivo ones; the t-bars assay for oxidation in canola oil has been criticized for lack of specificity. 24:16 - No compelling evidence showing oxidation from canola oil in humans, but advisable to avoid high-temperature cooking like deep frying. 24:45 - The smoke point of canola oil is around 200°C, and it's better to stay below that temperature. 25:40 - Oxidation alone doesn't mean toxicity, and it's crucial to consider the net effect in humans. 26:09 - Large studies suggest people cooking with canola oil have a lower risk of cancer than those using butter and similar risk as those using olive oil. 27:04 - Comparing oil to whole food sources of fat, there's little difference in health metrics when using canola oil. 27:54 - Trials like Lyon and FINGER used canola oil as part of a Mediterranean diet and saw positive health outcomes, though they made multiple changes. 28:24 - Most evidence indicates the safety and potential benefits of canola oil, but there's still a need for more specific research. 29:17 - Personal preference is essential; canola oil isn't a dietary necessity, and individuals should make their choices. 29:48 - Challenge claims about canola oil's toxicity by asking for evidence from human trials or cohort studies.

Thank you! No one else it talking about this from a scientific point of view.

Ty my friend. Always spot on in the examination. God bless you! I wish more educated individuals would do what you do overall.❤️

Hi Gil, I can't tell you how much your channel means to me. Recently diagnosed with Coronary Artery Disease and trying to work to find the best diet that works for me, your channel is an invaluable source that I always turn to. There are so many influencers out there, telling you this, or that, and I felt so confused. First I thought I was doing the right thing, then watching another video, I found I was doing wrong. I feel like I am settling into a diet that is most plant-based, with some animal products here and there, something that I feel is sustainable for me along with taking my meds. Thanks again for all your help, will always be watching your channel!

Solid information, as always. Thanks.

Dude..tnx for the video..keep making videos like these..i am a tyoe 2 diabetic and ur impact on my health is very commendable..my fasting glucose is nw stable and I don't take meth for months nw..tnx..

thank you for a very well put together information digest.

Thanks heaps for this video and all your others, love your work!

Thanks for bringing such a calm look at actual evidence to these topics. I have an acquaintance who is reading a new fad diet book and told me that not only are seed oils the cause of all our problems, but they actually somehow migrate up to the brain and coat our neurons - for years, even. Wow. I hope I can get him to watch a few of your videos. I think they would help assuage some of his food based fears.

Dear Gil, thank you for another great video with fresh evidence on the topic! Is there a possibility you will be covering effects of palm oil in comparison with other oils? Or have I missed it and this one you've already covered? Thank you for what you're doing!

I would love to give this video two or more likes but I can’t. Thanks a lot for your work!

Fascinating. Thanks. Yes there is a big current on social media bashing canola oil and glorifying coconut oil.

I appreciate these videos where you address the scientific studies and literature. Too many doctors on youtube are making all sort of claims but never reference any materials. I was listening to them thinking they were well educated but now I question their motives.

awesome, but one issue is that most Canola oils are made w pesticide laden Monsanto GMO Canola plants. Ive found organic canola oil at Whole Foods and that is what I'm using now. Also, the heating of the oil is indeed toxic to my body...so I only use small amounts and cook at lower temps (to reduce AGEs from both the oil and the meat) if I am stir frying and I do not eat fried foods if at all possible, but that's hard lol. Thanks for this update.

I like that this is thorough and comprehensive

Thanks much Dr. Gil, as always very informative and great presentation

The information online is so confusing; thanks for doing a deep dive!

Another excellent and informative video. Personally I prefer the whole food approach as oils are so calorie dense. If I want olive oil I eat olives, if I want canola oil, I eat canolis 😆

Thanks Gil. Good information. Paraphrasing the old adage: Moderation in everything.

more people should find your channel, free from ideology, I like that

Thanks for this great video! Please keep on your work!

Good clear information on oil uses, the why's and wherefores. Impressive.

This video is a breath of fresh air. Far from the preconceived notions about canola oil, it provides reassurance about this oil which has long been criticized, based on scientific arguments.

I would like to see a video discussing "adjusting for confounders", it is often used as a hand wave, and while I'm not saying it's being abused, especially in these cases, it does seems like the best area to smudge things in a favourable direction.

Yet another magnificent long form video chock full of data, insights and revelations which are extremely useful to all of us. THANK YOU! My basic takeaway after the first viewing is that canola is basically comparable or even slightly better than olive oil in most measured parameters. This is somewhat surprising based on all the seed oil hype. I spend a lot of money on high quality olive oil, and these results have me doubting the value of that consumer choice. Based on what I see here, it appears as if the cheap refined canola oil is at least the equal of the finest olive oil with the exception of flavor. That is a surprising revelation indeed. Yet scientific rigor often brings these surprising insights, and I say bravo to that!

It's funny, but in Germany canola oil has been recommended as a health food for many years. Linseed oil has been regarded as VERY healthy for many decades. Where did the anti-seed-oil hype come from?

Amazingly thorough video with interesting results

Thanks for clearing this up.

I have learned to maintain my cooking temperatures to stay under the smoke temperatures. I never bring the the oven temperatures over 345 degrees. That has meant I generally have longer cook times in the oven. Nice video!

You are a light of reason in a society leaning toward emotion, magic ,whatever. Thank you, Rik Spector

Thank you So much ! I am a believer in the scientific process but many want to just ignore facts. We have used Canola oil for the past few decades along with olive oils so I’m glad to see this presented.

Thanks for breaking this down.

Thank you, Dr Carvalho, for this high-quality survey of the evidence for/against canola oil. As an aging [75] Canadian man I'm proud of the fact that modern canola plants were bred/created/invented in the early 1970s at the University of Manitoba, and that Canada is the largest producer/exporter of canola seed oil in the world. The name "canola" was also invented in Canada to distinguish it from rapeseed oil, the name of which has unfortunate connotations. See Wikipedia for more...

Excellent. The internet needs more people doing reports of your caliber. I sub'd.

As usual best nutrition channel there is. And excellent Twitter too

At 19:23 you talk about the term "wash-in" diet. This can be used, to see a difference in case a certain food is usually already in the diet. I would love to hear your analysis about eggs, because I understood there is this effect, that if someone is eating zero eggs, adding x amount of eggs per week has a big effect on cholesterol level, whereas if someone is already eating several eggs a week, adding x amount of eggs has now effect on cholesterol (a plateau). I saw some medical doctors show graphs of this. I would also like to know, why people who have familiar hypercholesteremia are recommended not to eat eggs (at least that is what I heard from people with this disease, whose doctors recommended them to avoid eggs). If eggs do not raise cholesterol levels, why then are people with this disease recommended not to eat them? Thank you so much for your work.

Somewhere, there is a study that shows that olive oil has anti- inflammatory properties ... 🤔💭

Thankyou! This has been doing my head in for years re oxidation vs smoke point

Love these in-depth videos. Changing from butter to Canola.

Great video Dr. Carvalho. I'd suggest making a video on cooking sprays if you haven't already, comparing them to oils for cooking.

Yes yes yes!! Thank you for fighting quackery one day at a time doc!!

I appreciate facts and research on research. Thanks a lot.

The thing is canola oil is the main fat used in many highly processed foods because it is much cheaper than good quality butter and olive oil. Such products are definitely linked to higher mortality. This could be a confounder for the link between canola oil and mortality but hey, i do not necessarily need to use canola oil so I won’t add it in until there is actual conclusive evidence for it.

Great video! So many "experts" will say this food or that oil is toxic and must be avoided, and they say it with authority - and without evidence. I appreciate your evidence based approach to evaluating dietary components. After this video, I feel safe in using canola oil for light frying of my food or as a salad oil. Looking forward to more content!

Thank you. I've been buying products that have Olive oil instead of canola for quite some time because of not sure of the whole oil discussion. most of the times it's been fine but occasionally a pain when some places don't carry the alternatives. I usually look for studies on things when I hear them, ie look up studies on specific diets, specific foods, etc, but never really looked into oils. I'll have to look up some of these studies.

I know this off topic but I would ask. What’s your opinion on sodium bicarbonate good for kidney issues? Please your opinion

Consistently nice content 👍

If only I had this level of instruction in my study days..

Thanks for your video, very helpful.

Thanks for the video. I've been trying to do the Mediterranean diet. But since Olive Oil so so expensive I've been using Canola oil instead. I've been seeing a lot of people talk bad about Canola oil and I think your video made me feel a little better about using it.

Super interesting and well explained

Excellent content, thank you!

Fantastic to watch a lucid response to the nonsense.

Thanks. Great info and wonderful that you backed it up with real research. Like to add that canola oil also has an excellent balance between omega 3 and omega 6 fatty acids.

Great information, thank you.

An excellent work!!! Congratulation!!

I prefer no oil. However, really appreciate this comprehensive and unbiased video.

I wanted to watch your take on canola oil because I recently read Chris Knobbe's take on all seed oils - canola, vegetable, corn, sunflower, all of them - and he is absolutely against them. Especially when combines with sugar, white flour and processed foods. Us poor consumers get caught in the middle with one saying something is healthy, the other that the whatever is toxic. You'd think by now it would be sorted out.

Great walkthrough! I wonder why it was not mentioned, that Canola is major provider for essential ALA n-3 for the general population (who is not into flax and chia seeds) to meet the RDA. And that may likely be a big factor in a dramatic result study like the Lyon one - which took place before the time when Canola was widespread after invention, and when ALA RDA was rarely met. There is another striking study PMID 17955332 ("Rapid declines in coronary heart disease mortality in Eastern Europe are associated with increased consumption of oils rich in alpha-linolenic acid"), just 'quasi-randomized' by timing, but very specific compared to Lyon and FINGER. The decline is about factor 2 and can be drilled down quite well to the increase in ALA (mainly Canola introduction) at different times for different countries.

You have to do this video shirtless in a grocery store for me to believe it though

You should make more of these videos about every type of oil out there.

Thanks - great content

Excellent as always.

Excellent.