Obesity and Metabolic Syndrome

Obesity and Metabolic Syndrome | Clinical Medicine

Рет қаралды 19,309

Күн бұрын

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Ninja Nerds!
In this lecture, Professor Zach Murphy will present on Obesity and Metabolic Syndrome. We will discuss the pathophysiology of obesity, focusing on the imbalance between caloric intake and energy expenditure, and Metabolic Syndrome, characterized by a cluster of conditions including high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels. The lecture will include a discussion on the clinical manifestations of both conditions, such as increased risk of cardiovascular disease, type 2 diabetes, and other health problems. The digital presentation will begin with the diagnostic approach, highlighting the criteria for Metabolic Syndrome diagnosis and the importance of body mass index (BMI) for assessing obesity. Finally, we will review management strategies for both conditions, emphasizing lifestyle modifications such as diet, exercise, and in some cases, pharmacotherapy and bariatric surgery for obesity. Enjoy the lecture and support us below!
Table of Contents:
0:00 Lab
0:07 Obesity & Metabolic Syndrome Introduction
0:42 Pathophysiology of Obesity
7:17 Metabolic Syndrome
8:28 Caloric Intake
10:18 Caloric Expenditure
12:56 Complications of Obesity & Metabolic Syndrome
30:15 Diagnostic Approach to Obesity & Metabolic Syndrome
31:13 Treatment of Obesity & Metabolic Syndrome
37:51 Comment, Like, SUBSCRIBE!
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Пікірлер: 29

@odemi2537 2 ай бұрын

Each time I am watching another lecture with Ninja Nerds, my heart fills with so much gratitude. I am sharing them with anyone I know. You are definitely a gift, Professor Zach Murphy, and of course, your entire team. I graduated a while ago, and I am still coming back to these lectures over and over.

@agadooska 3 ай бұрын

NAFLD is now called metabolic dysfunction-associated steatotic liver disease (MASLD), I think we will need to get used to the new term soon.

@pasindusangeeth309 Ай бұрын

Is it also called MAFLD ?

@mostafael-dya4916 2 ай бұрын

Thank you zach and to all your team members for this great effort.

@BlndDler-zm4mu 2 ай бұрын

keep up the great work, thanks so much this helped so much no doctor in my college could explain it like you. Also love the new format for the lectures

@kalyanirajalingham1286 6 күн бұрын

You're fantastic! Your videos helped a lot! Thank you!!!

@valviv 3 ай бұрын

Great video, thanks Ninja Nerd!

@AhmedKhaled-zy6er Ай бұрын

You are the best of the best, man !!! 💓

@peuppeuppeup 2 ай бұрын

thanks for u dedication🎉

@vincentcyrilliansantoso9858 3 ай бұрын

This is awesome!

@anjalimaurya_4679 3 ай бұрын

Your video are really helpful to everyone 👏👏💫💫

@JTmoto 3 ай бұрын

Doing a literature review related to MASLD and obviously obesity, this video helped understand the concept way better. ⚕️✨

@shahiramohammadi7284 3 ай бұрын

Zach is my super ninja hero 💐💐

@serenitysel Ай бұрын

Man the new sleeves look so cool!

@ok6109 2 ай бұрын

Thanks❤❤❤

@Bedlaminhavana Ай бұрын

YOU... YOU ARE THE GOD OF PHYSIOLOGY. I'M A FAN.

@brofred7623 3 ай бұрын

Благодарю вас

@casualonemmo-player2167 2 ай бұрын

Regarding the clogging up inside of the blood vessels... if you loose a lot of weight, and get into a normal bmi range... will most of the clogging get removed by itself? *or is that "damage" permanent?

@eveberry9215 Ай бұрын

thanks ninja nerd

@finncsprivatechannel2215 3 ай бұрын

With regards to meds, antihistamines, especially centrally acting, are a massive cause of fat-specific weight gain and insulin resistance. Drugs like olanzapine will cause the most weight gain owing both to potent D2 and H1 antagonistic effects.

@TheSeahealth Ай бұрын

I really like your explanation, Prof. Zach, especially biochemistry and metabolism, but you have to consider another concept about obesity, namely that it starts with hyperinsulinemia due to high carbohydrates...thank you

@TheSeahealth Ай бұрын

not only just calories

@TheSeahealth Ай бұрын

how ketogenic diet?

@sajiruddinsk8129 Ай бұрын

Allways follow to you.

@CoachSusie Ай бұрын

I love you

@sanjith1179 3 ай бұрын

6 th like sir, I'm pratheesh from india( tamilnadu).big fan of you sir.say one hii sir.

@sciencesimplified3890 3 ай бұрын

I think this video should be re-made. There are different theories of the pathophysiology of metabolic syndrome. Many argue excess calories cause hypertrophic adipose tissue to undergo lipolysis, releasing Free fatty acids(FFA) into blood where it enters skeletal muscle (forming DAG which inhibit PKC which inhibit the insulin receptor) and also the high flux of FFA entering the liver up regulates VLDL secretion. The biochemistry defending this has been established in vivo in humans using NMR spectroscopy. Other evidence is the actos medication increases adipose tissues capacity to store FFA, reducing lipolysis and reducing these symptoms, also on the opposite spectrum the disease lipodystrophy reduces adipose tissue capacity to store fat, increasing lipolysis and FFAs entering blood and exacerbates these symptoms. I need to emphasize, im not saying the obesity and FFA theory is dogma, however to say the adipokines are definitively the cause I personally believe is inaccurate and should be emphasized is theoritcal

@sheilaherrera8584 3 ай бұрын

How about you make your own video