I still have to test it out. But my guess is, these relics would still be very powerful and enough to get through RO easily.

On my testing, karnak's heal was not converted to attack when using spear. But this was before the recent update, maybe they have fixed it however, i havent checked. If it works then spear is a fantastic choice otherwise i think book of hatred is not bad. If your team cannot survive then Undying shield is a good option.