Perutz Lecture 2022 - Therapeutic Opportunities in Glycoscience - Carolyn Bertozzi

  Рет қаралды 7,618

MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

Күн бұрын

MRC Laboratory of Molecular Biology Max Perutz Lecture 2022
Therapeutic Opportunities in Glycoscience
Speaker: Carolyn Bertozzi, Anne T. and Robert M. Bass Professor of Chemistry, Baker Family Director of Stanford ChEM-H, and Howard Hughes Medical Institute Investigator.
Abstract:
Cell surface glycans constitute a rich biomolecular dataset that drives both normal and pathological processes. Their “readers” are glycan-binding receptors that can engage in cell-cell interactions and cell signaling. Our research focuses on mechanistic studies of glycan/receptor biology and applications of this knowledge to new therapeutic strategies. Our recent efforts center on pathogenic glycans in the tumor microenvironment and new therapeutic modalities based on the concept of targeted degradation.
Read more about the lecture and Carolyn's work here: www2.mrc-lmb.cam.ac.uk/caroly...
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About the MRC Laboratory of Molecular Biology (LMB):
The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Its scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health.
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Пікірлер: 10
@toryramsay8914
@toryramsay8914 Жыл бұрын
Thank you for being so clever! Humanity needs more people like you who are obviously extraordinarily clever but have managed to combine that with sustained enthusiasm, humility, and kindness. Thank you
@jennifergrinder2602
@jennifergrinder2602 2 жыл бұрын
Dr. Bertozzi's work in glycochemistry is so exciting and TPD will change everything.
@cosalidra759
@cosalidra759 Жыл бұрын
Here after she won the Nobel prize 🏆 today!
@gloriaroma-sandiegorealest4037
@gloriaroma-sandiegorealest4037 Жыл бұрын
Thank you for choosing to go into Chemistry and for being deeply interested in doing work that saves people from dying from cancer. It’s because of you that people like my husband may be able to live on being my life long love and partner as well as loving father to his children.
@KS-xg9ht
@KS-xg9ht Жыл бұрын
Awesome lecture, fascinating topics regarding Cancer
@mahmoudsaif7246
@mahmoudsaif7246 2 жыл бұрын
Thank you
@arthurv4401
@arthurv4401 Жыл бұрын
Fabulous
@Hisloyalservantslistenlove613c
@Hisloyalservantslistenlove613c Жыл бұрын
Why not use polyclonal antibodies instead of monoclonal ?
@krupanidhi912
@krupanidhi912 Жыл бұрын
Very interesting madam Bertozzi that you are more a molecular immunologist rather than a chemist. However good sialiac acid information is delivered because of its prominence in cancer cell. Siglacs are other focal points in your lecture as CTLA4 and PD1 in developing immune checkpoint therapy as given by Tasuku Honjo and Allison. Great madam
@nirmalyaghosh7187
@nirmalyaghosh7187 Жыл бұрын
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