Pharmacology - ANTIBIOTICS - CELL WALL & MEMBRANE INHIBITORS (MADE EASY)

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Antibiotics, also known as antibacterials, are a group of drugs used to treat various infections caused by bacteria. Antibiotics work by either selectively killing (bactericidal) or inhibiting the growth (bacteriostatic) of bacteria. This pharmacology lecture covers topics such as classification of antibiotics; cell wall structure of Gram-negative bacteria, Gram-positive bacteria, Mycobacteria; mechanism of action and side effects of Cell Wall Synthesis Inhibitors: Beta-lactams (Penicillins, Cephalosporins, Carbapenems, Monobactams), Beta-lactamases (Avibactam, Clavulanic acid, Sulbactam, Tazobactam), Fosfomycin, Cycloserine, Vancomycin, Bacitracin, Antimycobacterial drugs (Isoniazid, Ethambutol), mechanism of action and side effects of Cell Membrane Integrity Disruptors: Daptomycin, Polymyxins.
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Source of diagram depicting the enzymatic steps involved in S. aureus cell wall synthesis: www.biomedcentral.com/1471-218...
0:00 Intro
2:02 Bacterial cell wall structure
3:02 Beta-lactams & Beta-lactamases
6:18 Enzymatic steps of cell wall synthesis
8:24 Fosfomycin, Cycloserine, Vancomycin, Bacitracin
11:38 Mycobacterial cell wall inhibitors
14:24 Cell membrane integrity disruptors

Пікірлер: 152

@SpeedPharmacology 8 ай бұрын

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@SpeedPharmacology 6 жыл бұрын

Don't forget to watch Antibiotics part 2 -------> kzfaq.info/get/bejne/a66BoNmCr73efo0.html

@annisanirmala1220 2 жыл бұрын

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@mogantisunilkumar5838 6 жыл бұрын

Thanking you sir for your lectures. Waiting for other antibiotic lectures sir

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@jillfu8408 Жыл бұрын

Thank you very much Sir. Regarding daptomycin, may I ask why the leakage of potassium causes depolarization rather than hyperpolarization?

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Hi sir, do you have a video for cephalosporins also?

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Please upload many more videos in chemotherapy

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Thank you.

@rashmigoswami4047 Жыл бұрын

Sir I have a question....It is generally said that bactericidal and bacteriostatic drugs are antagonistic to each other but why some combinations such as cefexime and azithromycin are used

@yeshadesai1157 6 жыл бұрын

can you please upload video about emetics -antiemetics and diarrhea & constipation

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He has them on his channel now

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May God bless you & your loved ones😊

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Thank you

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Thank you🇸🇴🇸🇴

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Please upload video on Anti viral and Anti cancer agents.

@5onfsharitheone939 5 жыл бұрын

Thanks

@chonhonglam8787 3 жыл бұрын

Thanks a lot Sir. But i have a qusetion about the Daptomycin mechanism. "such as potassium to leak through causing depolarization of membrane" why is depolarzation? positive ion out--> inside more negative than outside --> it should mean repolarization or hyperpolarization. Am i correct or not? Thank you.

@Wesley_semeniuk96 5 жыл бұрын

Please could you make a video on Transverse myelitis?

@SajjadAli-sv3qt 3 жыл бұрын

Thanks from Microbiology

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Could you please make videos for GIT drugs

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Do you have a video on anti viral drugs?

@waseemkhan-py7gn 6 жыл бұрын

Sir next video drug asthma 😊 or drug for status epilepticus..

@SaadSaad-mb4py 4 жыл бұрын

Good very good

@MrsLee_143_ 3 жыл бұрын

5:38 What about Carbapenemases ?? carbapenem antibiotics may dont using with beta lactamases but there is carbapenem resistant bacterias.

@jamiecarter7295 6 жыл бұрын

Is there a part 2?

@SpeedPharmacology 6 жыл бұрын

Yes. I'm currently working on it. Make sure you subscribe and enable notifications if you want to be notified as soon as it's uploaded. Thanks for watching!

@nasirkhan-cx6uo 3 жыл бұрын

1. Are the antibiotic producing isolates sensitive to known antibiotics? 2. If so, what does this tell us about the isolates? How might this relate to the antibiotics they produce?