How to establish MACO Value during cleaning validation

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Pharma Growth Hub

Pharma Growth Hub

Күн бұрын

This video will walk you through various ways to establish MACO Value during cleaning validation, how to define swab limit and how one can identify worst case scenario

Пікірлер: 48
@prasangitv3658
@prasangitv3658 Жыл бұрын
From long back am searching for this , now I got information about this , thank you professor
@subratmishra6468
@subratmishra6468 Жыл бұрын
I want to give 1000000 likes for this Crystal clear clarity sir....
@Pharma-7358
@Pharma-7358 10 ай бұрын
Iam Working in Cleaning Validation Department And it is So Useful
@anuragprakashtiwari1839
@anuragprakashtiwari1839 3 ай бұрын
Nyce
@akashgondaliya8537
@akashgondaliya8537 2 жыл бұрын
Excellent sir, superb explanation......
@buddepumohanarao8309
@buddepumohanarao8309 3 жыл бұрын
Very nice information and thank you sir
@pharmagrowthhub3083
@pharmagrowthhub3083 3 жыл бұрын
Most welcome
@amitgupta-yr5pl
@amitgupta-yr5pl 2 жыл бұрын
This is great presentation on cleaning validation
@yogeshpatel8860
@yogeshpatel8860 Жыл бұрын
Very nice way to explain in detail,thank you sir
@bhavins209
@bhavins209 3 жыл бұрын
Sir, we are from pharma industry and your video has been really helpful in understanding the concept of cleaning validation. Can u please provide the reference documents or guidelines relevant to the data mentioned in this video as we are facing many queries on this topic during audits!
@dattashinde5101
@dattashinde5101 2 жыл бұрын
Very nice sir easily understood how to calculate MACO value
@sivaprasadsiriki1241
@sivaprasadsiriki1241 2 жыл бұрын
Very interesting and can easily understood, thanks for valuble information thank you sir🙏
@Vikaspatil123-l9n
@Vikaspatil123-l9n 3 жыл бұрын
Very informative, thanks for sharing this 😊
@pharmagrowthhub3083
@pharmagrowthhub3083 3 жыл бұрын
My pleasure 😊
@dhirenheisnam9992
@dhirenheisnam9992 Жыл бұрын
Bless you, sir. It is so helpful .
@harikrishna851
@harikrishna851 3 жыл бұрын
Thank you
@babu200810
@babu200810 3 жыл бұрын
Good presentation. How would the worst case scenario be determined when you have to consider solubility, colour, fragrance, PDE.
@pharmagrowthhub3083
@pharmagrowthhub3083 3 жыл бұрын
God point. White in colour + highly insoluble in water = worst case
@gudiyakumari6774
@gudiyakumari6774 3 жыл бұрын
@@pharmagrowthhub3083 ooooo
@HamzaElMouaffek
@HamzaElMouaffek 8 ай бұрын
I have the same question, first you need to determine the worst case product by considering cleanability colors solubility... Then you have to calculate the worst case maco. Please feedback, if you find an answer.
@rohitbrahmbhatt5462
@rohitbrahmbhatt5462 Жыл бұрын
Sir me and my boss both are fan of you ... U r doing excellent job... Only one poin need to be consider that give reference of guidelines which make complete preparations of interview.😊😊😊
@nareshbabuMekala
@nareshbabuMekala 2 жыл бұрын
Very helpful
@vadlavallikanakarao3154
@vadlavallikanakarao3154 Жыл бұрын
Good information sir
@anurai3178
@anurai3178 2 жыл бұрын
Thank you for your video.. really helpful
@jonnadulapavan5548
@jonnadulapavan5548 2 жыл бұрын
Very informative session...Tq so much sir..
@praveenmanapragada1684
@praveenmanapragada1684 2 жыл бұрын
Dear sir , Thank you for giving the valuable information . Here in conversion of µg/dm2 to ppm for swab , swab diluent volume taken as 10 ml .kindly explain how can i fix the volume of swab diluent.
@Learnwithsimon27
@Learnwithsimon27 2 жыл бұрын
very nice explanation, sir.
@toplistsmania2845
@toplistsmania2845 3 ай бұрын
Plz answer 1.What is safety limit for injectable. How we calculate safety factor for specific API. 2. What will be the batch size. Is it total bach size of product or only quantity of API in batch.
@nehamansoor9144
@nehamansoor9144 7 ай бұрын
Is 1500 dm2 total surface area of equipment?
@dipakdeore2954
@dipakdeore2954 Жыл бұрын
Nice
@utkarshvyas3185
@utkarshvyas3185 2 жыл бұрын
Thank you sir ...
@gulammuhiuddin889
@gulammuhiuddin889 6 ай бұрын
How to calculate Maco of different product manufacture in same vessel by rinse method
@kiranpillalamarri4517
@kiranpillalamarri4517 2 жыл бұрын
Superb bro
@subhanid6656
@subhanid6656 3 жыл бұрын
Dear sir, please help me in how to development dissolution method for NMC molecule
@mansouralajeemi9101
@mansouralajeemi9101 2 жыл бұрын
@prasadmallavarapu7740
@prasadmallavarapu7740 2 жыл бұрын
Thank you sir..........
@AmanYadav-tc4um
@AmanYadav-tc4um 2 жыл бұрын
Thank you sir 🙏
@tanajikadam2455
@tanajikadam2455 2 жыл бұрын
Very good
@maheshupadhya7304
@maheshupadhya7304 2 жыл бұрын
Fantastic interpretation Sir thank you.. Have a doubt on safety factor, for ex.how much to consider if the range of 10 to 1000 in case of topical, is it any number between 10 to 1000 suppose I select as 200 as safety factor or the maximum as 1000 how it is taken. Thankyou
@rohitbrahmbhatt5462
@rohitbrahmbhatt5462 Жыл бұрын
10 should be take to get wort case of MACO value
@prafuldineshgawadgawad3461
@prafuldineshgawadgawad3461 Жыл бұрын
Hiii sir how to define acceptance limit in ppm for cleaning validation
@mmh7817
@mmh7817 2 жыл бұрын
Sir how to set the limit for that product whose MACO is less than LOQ AND LOD which guidelines to be followed kindly suggest.
@sunilshedage9503
@sunilshedage9503 3 жыл бұрын
sir, how did you calculate MBS 5 Kg = 50 000 000 mg
@subhanid6656
@subhanid6656 3 жыл бұрын
Bro 1kg=1000g 5kg=5000g So 1g=1000mg 5000g = 5000*1000mg=5000000mg I hope you understood
@heisenberg_chem
@heisenberg_chem 3 ай бұрын
Can i get pdf for reference
@faezabutt7580
@faezabutt7580 2 жыл бұрын
Is there any training on cleaning validation by napte bhaskar? If anyone knows kindly share link please
@pharmagrowthhub3083
@pharmagrowthhub3083 2 жыл бұрын
Live workshop on Cleaning validation: us02web.zoom.us/webinar/register/8416507954921/WN_b_S4Wk6rS-ukrLy8CBV9mQ
@rohitbrahmbhatt5462
@rohitbrahmbhatt5462 Жыл бұрын
Sir how to calculate safety factor???
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