Curcumin: Some should use it, some should not. Which are you?

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Physionic

Physionic

Жыл бұрын

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[1] doi:10.3389/fendo.2021.669448
[2] doi:10.1016/j.ctim.2019.02.014
[3] doi:10.1186/s13098-019-0437-7
[4] doi:10.2337/dc12-0116
Created with Biorender.
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Пікірлер: 260
@azalea1404
@azalea1404 4 ай бұрын
I suffer from myalgic encephalomyelitis (ME) - a multi-system autoimmune disease. Among the many physical malfunctions ME encompass, neuroinflammation is one of them. I experience great improvement by taking 1 teaspoon of curcumin mixed with a teaspoon of freshly grined pepper, and a teaspoon olive oil - all disolved in juice, tea, coffee, or yoghurt naturel. Curcumin does NOT taste good, but it certainly helps on my headaches, fatigue, and cognitive problems. Thanks for a great science channel ❤🙏❤
@randallsample1005
@randallsample1005 Жыл бұрын
I hadn't realized that curcumin helps with blood sugar issues. It would be interesting to learn if its anti-inflammatory properties are truly helpful for cardiac concerns.
@edwardanderson1053
@edwardanderson1053 Жыл бұрын
Curcumin also has anti-carcinogen and anti inflammatory properties for musculature and tendons as well, these are the subjects of several studies.
@Maazzzo
@Maazzzo Жыл бұрын
As someone with multiple inflammatory conditions (fibre, EDS, arthritis) this is what I am interested in when it comes to curcumin.
@colmrooney414
@colmrooney414 6 ай бұрын
@@Maazzzo if you change your diet you can overcome arthritis and inflammation.
@teddybearroosevelt1847
@teddybearroosevelt1847 6 ай бұрын
@@colmrooney414Yes, definitely. Lots of vegetables and the occasional bit of fruit will do a lot for you to reduce inflammation and many other aspects of the Mediterranean diet will help you greatly. For one thing, stay away from processed food as much as you can and avoid alcohol as well.
@petemitchell6788
@petemitchell6788 2 ай бұрын
If you’re such an expert, start your own KZfaq channel instead of poaching others.
@edithh6779
@edithh6779 9 ай бұрын
Garry Small ( UCLA, I think,) did a trial to measure the benefits of Theracurmin, a nanoparticle form of curcumin. It was relatively successful in reducing cognitive decline. Granted it was as a small study, but it has found its way into AD prevention protocols.
@oleinkar3933
@oleinkar3933 10 ай бұрын
I take curcumin supplements regularly to lower my inflammation. I have ankylosing spondilitis, so I get flare ups often. It really helps a lot and I have managed to keep my autoimmune disease under control without biologics. Just using supplements, anti inflammatory diet (avoiding sugar and other triggers) and exercise. Thanks for this video. Im a big fan of your work. Thank you!
@pipp33
@pipp33 4 ай бұрын
Would you mind sharing your supplement stack for helping with AS and inflammation?
@sylviaanderson704
@sylviaanderson704 Жыл бұрын
So happy to have found your You tubeI I liked and hit the bell,I was happy to hear about your info on curcumin
@zanzabar7878
@zanzabar7878 Жыл бұрын
Just discovered your channel, been binge watching. Fantastic content thank you
@ConnieWobbles
@ConnieWobbles Жыл бұрын
I'm really happy about that 5-10% result! To me that's significant enough to include curcumin in my supplement stack. I'm not diabetic but I'm definitely insulin resistant, and my crp increased after weight gain, so I've been making lots of changes to improve my health. I think small changes can add up to an improvement over time. I'm not a science type but I enjoy learning from this channel.
@Physionic
@Physionic Жыл бұрын
Great, Connie. :)
@GregariousAntithesis
@GregariousAntithesis 11 ай бұрын
Moderate heavy resistance exercise will address most issues.
@barbarashirland9078
@barbarashirland9078 10 ай бұрын
Thank you. Always appreciate your research based info.
@alphatauran
@alphatauran 4 ай бұрын
You are definitely the best nutritional podcaster I have encountered so far.
@DoritoWorldOrder
@DoritoWorldOrder 4 ай бұрын
He sounds very confident and convincing to a layperson, but he doesn't actually know what he's talking about on most things, and doesn't really understand how to read study literature.
@NaturopathTroy
@NaturopathTroy 7 ай бұрын
Nic- your channel and insights are incredible. Forever grateful. I could literally sit and watch all your videos all day long. Perhaps I am a nerd, too? Thanks man!
@lescoursdefrancaisdemonsie2826
@lescoursdefrancaisdemonsie2826 Жыл бұрын
Thanks a lot for this very interesting free review ! Great video in a smart format 😊
@sharonkende4774
@sharonkende4774 Жыл бұрын
How cool (and informative) is this video? Wow, kudos. Great explanation of how curcumen works
@outriding
@outriding 9 ай бұрын
Thanks for the information you present.
@Physionic
@Physionic 9 ай бұрын
Thank you!
@idme8295
@idme8295 4 ай бұрын
I read this at first as Circumcision: Some should use it, some should not!"
@RCV2024
@RCV2024 11 ай бұрын
Eagerly looking forward to your carnivore eval video to drop 🔥
@supernova1976
@supernova1976 Жыл бұрын
This is very cool indeed . i am a big advocate for turmeric supplementing , i discovered the benefits in fast recovery form colds and any infections, then started researching the anti-inflammatory properties , didn't look into blood sugar effects for some reason it was always being dismissed by Drs :) I wander why 😇. Thank you for sharing .
@joyfour4995
@joyfour4995 Жыл бұрын
Good morning Nic, I love your videos! They are very informative, and so easy to understand. Keep up the good work!
@Physionic
@Physionic Жыл бұрын
Thank you, Joy. :)
@adm129100
@adm129100 Жыл бұрын
Hope you do another video on curcumin as a painkiller / cox-2 inhibitor
@cheriseelliott9230
@cheriseelliott9230 Жыл бұрын
Great job! 👍🏼
@Physionic
@Physionic Жыл бұрын
Thank you!
@marcob.7801
@marcob.7801 Жыл бұрын
Just LOVE ALL your stuff Nic! you are my favorite "physionic" YT channel! You present in an intelligent, concise and digestable (pun intended) fashion and are never pretentious! You sir, are a genuine teacher and seeker of the truth! I've been a subscriber for some months and look forward to all your new content! Thanks and Kudos "professor!"
@Physionic
@Physionic Жыл бұрын
Thanks so much, Marco!
@spockboy
@spockboy Жыл бұрын
Excellent videos. Extremely informative, pleasantly explained, you've found your calling son.
@Physionic
@Physionic Жыл бұрын
Thanks, SB. I’ve seen a few of your comments around. Thanks for watching.
@michelew2191
@michelew2191 11 ай бұрын
I've never heard of "inflammation genes", that seems interesting. For what it's worth, I've noticed turmeric supplements seem to settle my ibs symptoms, but never did enough experimentation to know for sure. This video doesn't exactly explain that, but I was told I have pre-diabetes around the same time that my ibs symptoms started kicking up...maybe some sort of pancreas/liver/insulin/sugar connection? Really don't know, I just take shots in the dark until I find things that work but videos like these help inspire me and give me ideas on what things to try more or less of. Gonna go back and do more experiments with turmeric now. Ty!
@Marc_de_Car
@Marc_de_Car Жыл бұрын
Thanks
@jeffreyjohnson7359
@jeffreyjohnson7359 9 ай бұрын
Dr. Stanfield actually does recommend for people with osteoarthritis. Lucky me, I have that and t2d...
@Galdring
@Galdring 9 ай бұрын
Great video! Do you recommend supplementing, or just eating a bunch of spice? Add fat for increased absorption?
@jakehayes1345
@jakehayes1345 Жыл бұрын
Great video! Now I feel even better taking Curcumin (Turmeric) great channel, I'm glad I found it. 😎
@Physionic
@Physionic Жыл бұрын
Thanks, Jake! I didn't see your other comment.
@pong4life
@pong4life Жыл бұрын
I just started curcumin since studies have shown it can help with inflammation and muscle recovery. I will know soon weather that works on me or not. Dr Stanfield is more interested in life extension, not muscle recovery. It's nice to know curcumin can also help with blood sugar.
@DalyD
@DalyD Жыл бұрын
I hurt my back years ago due to a herniated disc and I am currently going through a flare-up. I am doing a number of things to get better, but I've been taking a curcumin (with piperine!) supplement daily to reduce inflammation in my sciatic nerve. I don't think it has made a dent in pain levels, but I'll continue going through the whole bottle in case the anti-inflammatory effects compound and help me get back to a pain-free state quicker. Diabetes also runs in my family though, so as I get older, I'll definitely keep a close eye on this one. Hopefully by the time I'm getting into late middle age these supplements are cheaper!
@jeffhutjens
@jeffhutjens Жыл бұрын
Apart from NFkB, curcumin also suppresses microglial and glutamate excitotoxixcity, very relevant in chronic pain.
@peterhoy2382
@peterhoy2382 Жыл бұрын
Hello again. I had been taking osteo biflex (Glucosamine/Chondroitin) for joint pain (side note: our yellow had unbelievable help when we gave it to her). However, my finger joints started to give me some pain (guitar player, not good). My primary physician (from India) suggested Curcumin. I got some and in a very short amount of time ... no more finger joint pain. I've been taking for several years now ... still no finger joint pain. Btw ... "Normal blood sugar numbers" before starting curcumin. Started Low Carb/Mediterranean ... really good blood sugar number (checking fasting insulin and A1c in addition to the standard fasting glucose number).
@aditya7955
@aditya7955 Жыл бұрын
Whats the curcumin dose you take? I have ankylosing spondylitis and want to try this
@martinlang9615
@martinlang9615 11 ай бұрын
I was pre diabetic prior to starting Carnivore (actually Lion “diet”…hate that word, really it’s a lifestyle). It’s been 2.5 months no longer pre diabetic. My CRP is low, but I would like it lower. I already have plenty Curcumin in a powder form with absorption agent, so I will start it again. I’m a chronic pain suffer, so anything to keep my inflammation low is a good thing. Apart from not being prediabetic I no longer have high blood pressure, sleep apnea. Love your videos. I’m a new Sub.
@Physionic
@Physionic 11 ай бұрын
Thanks for sharing!
@tiwidub8809
@tiwidub8809 4 ай бұрын
😂😂😂 Love it. Thanks. ❤
@O_Observer
@O_Observer Жыл бұрын
Guys, dont forget to check your lead levels using hair mineral analysis ( i think the name is metalogram). Currently Im treating lead in my body since it was the main responsible for my kidneys stones and the fact I took turmeric powder for years contributed for this I believe
@thomasmuller1850
@thomasmuller1850 Жыл бұрын
My vendor for such a test allows to use finger and toe nails too. I have heard, that a hair analysis can be affected by hair conditioners, shampoo etc. So could taking nails be better? How do you treat your lead level?
@O_Observer
@O_Observer Жыл бұрын
@@thomasmuller1850 There are some easy procedures to do in order to perform such tests like use neutral shampoos for some time before taking the hair samples. I used Dmsa following the schedule of Acc protocol to remove lead. Im not producing anymore the kidney stones after the treatment. I had to take magnesium with every meal in order to avoid them before
@lukaszklopotek
@lukaszklopotek Жыл бұрын
I wonder if curcumin extract has the same lead contamination problem as the 1:1 root powder.
@indridcold4210
@indridcold4210 7 ай бұрын
I'd love to see a study on people who had pre-diabetic levels of blood sugar who also took a reasonable amount of berberine. It seems that if the effects were additive, then the combination could extend a lot of lives. High A1C levels are directly related to CVD complications such as heart attacks, strokes, and CHF
@michaelmappin1830
@michaelmappin1830 11 ай бұрын
Ty❤
@keithbertschin1213
@keithbertschin1213 Жыл бұрын
Great video, no hyperbole, many thanks
@Physionic
@Physionic Жыл бұрын
Thank you, Keith!
@czarcoma
@czarcoma 12 күн бұрын
I am still trying to wrap my head around what inflammation is at the cellular and molecular level. My solid idea for inflammation is still "i banged a part of my body somewhere" or "certain of my glands are infected" and some parts of body is swollen beyond normal.
@vladmirgolobovic518
@vladmirgolobovic518 Жыл бұрын
Nice video. I think we need to start acknowledging though an inconvenient gap between what the studies say and what happens in clinical practice. Curcumin is often touted as this magic anti-inflammatory, and yet we still have people with autoimmune diseases having to go through strong immunosupressants. As an alternative therapy, I'd be much more interested in seeing the mechanism of Low Dose Naltrexone (LDN) than Curcumin, which has been gaining a lot of traction, in special now with the Long Covid RCTs. In general, people that seek LDN prescriptions have already tried things like Curcumin and other supposedly anti-inflammatory supplements. This leads me to believe that Curcumin is great in paper, but not so much in practice.
@okamsug
@okamsug 10 ай бұрын
It doesn't work on any illnesses that people anecdotally claim to have helped them. I've tried using it for arthritis and heart disease for many months with no improvement.
@IonidisIX
@IonidisIX 4 ай бұрын
It has helped with my IBS tremendously and I take 20,000mg capsules twice a day. Though from experimentation even 10,000 2x a day would be sufficient. I like the extra protection it offers to my gut pain.
@LifeWithRilla
@LifeWithRilla Жыл бұрын
I'm considering doing an extended water fast. I'm first going to go speak with my doctor & start documenting and posting about the results & how I feel. It would be great to watch videos you make on how things progress for me. The extra layer of accountability from another KZfaq would definitely aid in motivation!
@eliseville
@eliseville Жыл бұрын
I think non-scientist “nutritional science guru” Tom DeLauer covers a study showing curcumin powerfully instigating early autophagy.💪
@martinlang9615
@martinlang9615 11 ай бұрын
Did you see the 31st July video on water fasting? Good luck (maybe you have already done it by now).
@hometown1474
@hometown1474 6 ай бұрын
Your doctor will crap on the idea, guaranteed.
@TheMoicani
@TheMoicani 4 ай бұрын
Interesting.
@neilpickup237
@neilpickup237 2 ай бұрын
My doctor recommended curcumin to help with some medication side effects. I have suffered with migraine since late childhood, although it could be weeks between attacks, they tended to be in clusters leaving me low for a few days without early use of my medication for whenever I had an attack. After taking curcumin with success for many months, I noticed that my migraine medication (which I carried in my wallet) was out of date. I then couldn't remember when I last had an attack. I have now been free from debilitating migraines for over a decade. Interestingly, the only other period that I was migraine free was while I was on steroid treatment, so I am suspecting that my migraine was, to a degree, related to inflammation.
@sleeplessforawhile
@sleeplessforawhile Жыл бұрын
Thx so much for sharing with all of us your work and your down->top view. By the way... could you consider to do some videos about more "popular" supplements on "cancer" scenarios? ... yes .. I know... it´s a complex scenario to dive on, but... it coud be so interesting to see that under your "analitic" point of view.
@Physionic
@Physionic Жыл бұрын
I'm thrilled to do it!
@sleeplessforawhile
@sleeplessforawhile Жыл бұрын
@@Physionic I´m pretty sure that there will be a lot of people thrilled to watch that... A realistic (not necessarily good or bad) point of view is always necessary. Thank you... once again.
@trevorumback7602
@trevorumback7602 4 ай бұрын
Much cooler than 900% man my hopes plummeted, wiz guy hay 😅😂
@stevencraigbryan3770
@stevencraigbryan3770 9 ай бұрын
I use it and love it. I also like Glucosamine and MSM at 4gms daily which works best for me. What are your thoughts?
@jamescalifornia2964
@jamescalifornia2964 Жыл бұрын
Take with black pepper 😊👌
@saliksayyar9793
@saliksayyar9793 10 ай бұрын
It also stimulates glucose transporters in beta cells forcing increased secretion of insulin, the kind noted in sulphonylureas. Damaging to the beta cells.
@gl4thpgmail702
@gl4thpgmail702 Жыл бұрын
In what form do we take curcumin…do we just start putting turmeric spice and pepper on everything we eat? How much should we take? How often? Can someone help me to understand how to use this. Thank you in advance. ❤
@leondevries478
@leondevries478 Жыл бұрын
Wow very interesting information. I read that IL-6 is (for a big part) responsible for the feeling of fatigue while having for example the flu. Should turmeric/curcumin therefore help for people with CFS ? Very curious, thanks an best to you from the Netherlands…
@inhocsignovinces8061
@inhocsignovinces8061 Жыл бұрын
The reason I'm personally steering clear of Curcumin as a supplement is that it inhibits P-glycoprotein activity. The same reason applies to piperine, quercetin, and vitamin K2.
@xXxXxCGPBxXxXx
@xXxXxCGPBxXxXx Жыл бұрын
What does this mean in lay terms? I tried to find the answer but didn’t exactly get a sufficient answer. Interested…
@Dan-dg9pi
@Dan-dg9pi Жыл бұрын
This paper appears to suggest that P-Glycoprotein is a cause of cancer Multidrug resistance. www.ncbi.nlm.nih.gov/pmc/articles/PMC5198046/#:~:text=Curcumin%20as%20Modulator%20of%20P,models%20%5B21%2C33%5D.
@Santa-ny1yp
@Santa-ny1yp Жыл бұрын
@@xXxXxCGPBxXxXx P-gp protects the body from harmful substances by pulling it from the liver and kidneys into the urine and bile. It also helps maintain the blood-brain barrier. Since P-gp molecules are present in many organs like BBB, kidney proximal tubule, and bile ductule, their inhibition can potentially improve not only the absorption, but also the distribution, metabolism, and elimination of their substrates. this is google search so I can't translate. Looks like it has potential positive and negative effects.
@eliseville
@eliseville Жыл бұрын
Hindus who have been traditionally non-meat-eaters, have used turmeric dietarily in their daily curries and counteracted the diabetes their more carbaceous diets otherwise would have produced. They also got plenty of MK7 (K2’s calcium-directing form) from their many fermented pickle varieties🎉 I doubt many turned down curry or chutney because of P-glycoprotein worries.
@MrMikkyn
@MrMikkyn Жыл бұрын
I’ve got ankylosing spondylitis and I want to know why coffee and black tea help alleviate my back pain? I’ve read about how caffeine is bad and good in various ways, and how some people avoid it. I find it actually helps me, every time I drink it. I’m not sure what’s happening on the cellular level. I know COX-2, TNF, IL17, IL22 are involved in the inflammation. I also notice that cherry juice helps. I don’t know what’s going on there. Placebo? Anthyocyanins? No idea. I take Meloxicam sometimes in the evening if the pain persists, but I prefer a daily coffee in the morning, as the meloxicam has side effects like upset stomach and diarrhoea.
@DBMMMMM
@DBMMMMM Жыл бұрын
I had years lasting inflammations as result from heavy bruxism. Once in a while I had to use antibiotics, the inflammations lasted at least 20 years. Until the moments I started pressing my own 1000mg caps Kurkuma+pepper in 10:1..20:1 ratio, used 3000mg daily for half a year or so, in just 1 week the inflammations were gone and never returned. My dentist could not understand why it worked but it DID
@pierrejeanes
@pierrejeanes Жыл бұрын
Why not
@jodimichelleschoenherr
@jodimichelleschoenherr 4 ай бұрын
✝️ We love it. Great ❤ work 📰 News Show
@swissantiqueradios
@swissantiqueradios Жыл бұрын
I believe curcumin is a substance that deserves further investigation. Online there are several studies attesting to its benefits for relieving arthritis symptoms, going so far as to equate its results with the use of nonsteroidal anti-inflammatory drugs. For example, my wife started taking curcumin 3 months ago and her pains have reduced considerably. Unfortunately, there is not much money to do research on curcumin, I'm afraid the patents have expired.... 😅😅 Thank you for your science education work.
@the3cl3ctic
@the3cl3ctic 8 ай бұрын
Can you get the effect by taking powdered curcumin or is it better to take it fresh?
@tonyprice2256
@tonyprice2256 4 ай бұрын
I don't really bother with supplements. I simply add generous amounts of real turmeric and pepper to my foods - usually steamed veggies or ground beef.
@robertsmyk4102
@robertsmyk4102 Жыл бұрын
Elevated blood sugar is not the problem, persistent elevated blood insulin levels is the problem and so it would be interesting to know how curcumin affects the release of insulin and what is the mechanism.
@darrenbraynard4005
@darrenbraynard4005 Жыл бұрын
Dank music at the end, btw. Question: Could this inhibit beneficial inflammation?
@Physionic
@Physionic Жыл бұрын
Great question, and yes, Darren. It can.
@DM-jt4rh
@DM-jt4rh 11 ай бұрын
This is one of THE best scientific breakdown / bio hacking channels out there imho.
@idragonfly
@idragonfly 4 ай бұрын
I've been diagnosed with ME/CFS and have been taking Turmeric (with Piperine) to help curb the chronic inflammation that this condition tends to generate. My question is ... would Turmeric (with Piperine) be as effective as Curcumin - in this particular scenario? And ... Does Curcumin require Piperine for absorption - as well?
@homesignup
@homesignup Жыл бұрын
Excellent molecular mechanism info and love all your graphics!! I still take curcumin for its purported autophagy and general anti-inflammatory effects. I was wondering what you think of its use beyond anti-diabetic effects. Most people seem to have it in their stack for longevity reasons.
@Physionic
@Physionic Жыл бұрын
I can't say with any great level of confidence, because I haven't read the studies, themselves, but from a few scientific reviews, it seems to have more than just an anti-diabetic effect. Not sure about longevity, however. Thanks, Talia - hope you're doing well!
@Leucanthema
@Leucanthema Жыл бұрын
@@Physionic I have to admit I am little bit confused right now, I thought longevity benefit of curcumin was already kinda pointed out by you in this video kzfaq.info/get/bejne/msVje5BqttbVcoE.html
@Reversed82
@Reversed82 Жыл бұрын
@@Physionic i would love a video on curcumin's interaction with autophagy and other mechanisms explained by you. many of the papers seem like they fit right in your domain but i struggle to understand them directly.
@fmg4537
@fmg4537 Жыл бұрын
Agree with other comment, your voice is def ASMR worthy. Quick question buddy! How much Curcumin was seen to be effective? Was it Curcumin or Turmeric? And lastly, I do recall a previous video where you recommended taking with Pipercin for great uptake or am I confusing that for something else😉 -From Canada🇨🇦
@wturber
@wturber 5 ай бұрын
I routinely test on the high side of normal for fasting blood sugar (95-105 typically). Type II diabetes runs in my family. I get a lot of exercise and my blood sugar hasn't gotten any worse in five years. Nonetheless, I still am mildly concerned. So I did some checking on curcumin. What I've found is that I can routinely see my morning fasting glucose drop by about 10 mg/dL about an hour after taking curcumin and some black pepper. Yes, I just grind some up fresh and take it with the pill. An hour later, my glucose will be about 10 units lower. I've also tested an hour later multiple times with no curcumin and see no similar pattern of blood sugar dropping. There has been, however, one exception out of about 7 tests so far where my blood sugar did not drop after taking curcumin. Given that Metformin has real side effects (maybe reduces some of the beneficial effects of exercise and inhibit skeletal muscle gains) I'd like to avoid the medication. So maybe @Physionic is on the right track. This may very well be a good supplement for borderline/borderline people like myself.
@Physionic
@Physionic 5 ай бұрын
Thanks for sharing!
@polyrhythmm
@polyrhythmm 4 ай бұрын
Do you think pepper and curcumin could be a good treatment for fibromyalgia?
@cityinthesky1341
@cityinthesky1341 20 күн бұрын
Cumin, not curcumin, when added to a cup of ramen noodle soup is heaven for your taste buds. Someone should figure out a way to make a healthy version of a ramen noodle soup cup. When you think about how easy it would be add your favorite spices to it, this could have a significant impact on the lives of many.
@mikegriffin8403
@mikegriffin8403 Жыл бұрын
Your video focuses on curcumin's effect on blood glucose and diabetes. That is fine & good. But my impression of curcumin/tumeric's primary benefit is that it's an anti-inflammatory. I'm more accustomed to seeing berberine & cinnamon supplements presented for managing blood glucose levels.
@Physionic
@Physionic Жыл бұрын
I’ll need to dedicate some time to analyzing studies on curcumin and inflammation, then.
@eliseville
@eliseville Жыл бұрын
@@Physionic Your lecture just gave me more clarity on how it slows inflammation. I am more interested in how it interacts in our microbiome!
@IonidisIX
@IonidisIX 4 ай бұрын
IBS sufferer here. Hands down the best natural remedy I came across in my journey towards health is curcumin. I have been taking 20,000mg twice a day for the last 3-4 years and I can safely say, that it has no adverse effects (not that I am aware at least) and it has definitely helped with my gut inflammation issues. Thank God I came across this substance a few years ago because aging does not help with IBS (not to mention other auto-immune disorders).
@Sheboon
@Sheboon 2 ай бұрын
Which formulation are you taking now?
@IonidisIX
@IonidisIX 2 ай бұрын
@@Sheboon The same. I have also found butyric acid to be very helpful as well. So curcumin and butyric acid are the best out there (for my type of IBS at least).
@griffin2599
@griffin2599 3 ай бұрын
What do you think about turmeric/curcumin causing liver toxicity? I feel like you would have to take an excessive amount to do that. Maybe 10,000 mg plus ?
@grainiac7824
@grainiac7824 2 ай бұрын
My husband paid no mind to my efforts to manage my insulin resistance until his arthritic thumbs were killing him and I suggested he try it. He seemed sheepish as he acknowledged it worked
@DM-jt4rh
@DM-jt4rh Жыл бұрын
All participants were instructed to take three capsules with blinded labels of either curcumin or placebo twice a day (total of six capsules per day) for 9 months continuously. Each curcumin capsule has curcuminoid content of 250 mg.
@jodimichelleschoenherr
@jodimichelleschoenherr 4 ай бұрын
Question 🙋🏼‍♀️ Do you like your gift 🎁 ❤❤❤😂😂😂❤😜🧐🤓🥸
@CJP3626
@CJP3626 Жыл бұрын
Good informative video, i add about a gram or 2 of tumeric along with a bit of pepper(1/4g?) to my morning protein drink. I also add a gr of cinnamon. Question! Does circ & cinn conflict in any way. I thought i'd seen that , but i can't find it again. Anyone?
@davidfeldmann7497
@davidfeldmann7497 2 ай бұрын
Do these pathways you discussed explain why it usually helps with tonsil stones that I experience when I feel low energy? I still don't get who should not take it
@PeterTea
@PeterTea Жыл бұрын
Thanks! I guess as a type 1 diabetic I should keep taking my tumeric supplements. Is it important to take it with pepper? I remember that you mentioned in another video that pipian (not sure if that’s the right term) from pepper increases the absorption of curcumin substantially.
@Physionic
@Physionic Жыл бұрын
Yes, Peter - good memory!
@eliseville
@eliseville Жыл бұрын
Yep! But along with “piperine”which makes many substances (including my anti-seizure med carbamazepine) more bioavailable, fats help too. That’s why a warm & definitely fatty peppered “golden milk” is so powerful💪 (For Keto I make it with Milkadamia, MCT, pepper, turmeric, ginger, Ceylon cinnamon & cardamom, usually sweetened with Allulose. Yum! Coconut milk would work very well too, but has higher carbs to count.)
@tabithawolf4251
@tabithawolf4251 6 ай бұрын
“900%” Hahahaha! You got me! Curcumin went everywhere. I’m still getting it out of my keyboard.
@neuromax3766
@neuromax3766 6 ай бұрын
I started taking Curcumin 5 years ago. I was having problems with short term memory and a young man I knew said that his dad, who was the head of psychiatry at a big university hospital, was involved in a study of curcumin for short term memory that was showing good results. I started taking it and within 2 weeks my short term memory was noticeably better and still is. I'm not going to talk about the effect on my erections so - don't ask.
@danos5181
@danos5181 7 ай бұрын
Does Curcumin have benefits for longevity (regardless of diabetes improvements)?
@vanessac1965
@vanessac1965 Жыл бұрын
Can't remember where but found study saying raw is best, along with black pepper and something fatty like a bit of oil
@bryanstanley4295
@bryanstanley4295 2 ай бұрын
But it should still provide antinflammatory and antioxidant benefits for all people correct?
@robertlin6102
@robertlin6102 8 ай бұрын
Your previous video touched on how curcumin isn't absorbed into the blood stream or is inactivated by the liver. The conclusion of that video was that curcumin needs to be taken with pepperine. Is that combo what was given to the subjects in these studies? Something doesn't match if curcumin isn't absorbed into the blood but it does have an effect on insulin resistance and diabetes.
@Physionic
@Physionic 8 ай бұрын
Yea
@maxcarter3413
@maxcarter3413 4 ай бұрын
If curcumin increases insulin sensitivity then it should reduce C peptide meaning less stress from insulin production and possibly weight loss and reducing the risk of diabetes further in so-called healthy people. In other words, consider the impact of curcumin on the HOMA IR score before you conclude that healthy people see no benefit.
@mikeward9870
@mikeward9870 Жыл бұрын
Healthy user bias? Microbiome effect? Chronic side effects? Still much to figure out?
@brucejensen3081
@brucejensen3081 Жыл бұрын
I eat a lot of spicy foods and turmeric gets thrown in, it would seem incorrect not to do so. I dont think i need any more.
@Vogeln
@Vogeln Жыл бұрын
Thanks for a very interesting and thought-provoking video. Question: Is curcumin the only beneficial compound in turmeric? In addition to it's anti inflammatory and and anti diabetic properties, I've also read that turmeric has some neuro-protective and anti-cancer ones as well. Is there any truth to this and if so, can they all be attributed to curcumin alone or are there other compounds in turmeric that could be responsible?
@Physionic
@Physionic Жыл бұрын
It's the main compound, but it's still possible other compounds could also be of benefit. I would probably focus on curcumin, however. I haven't looked into those areas myself, yet, but I can tell you that I've read similar claims in the scientific reviews.
@anne9134
@anne9134 Жыл бұрын
So can you please look into brain inflammation.
@dailyoccasions9539
@dailyoccasions9539 Жыл бұрын
Will it help with Multiple Sclerosis?
@jamescalifornia2964
@jamescalifornia2964 Жыл бұрын
​@Anne 😮 Lately, it seems everyone's brain is inflamed !,
@eliseville
@eliseville Жыл бұрын
@@dailyoccasions9539 Any healthy anti-inflammatory will help you. But please research how high HORMONE D LEVELS can put MS into remission!!! Other necessary treatments are also combined. There’s an original Brazilian high D protocol & some in the US have been very successful, too (sorry I cannot remember their names, but should come up in a search💔)
@richardbreeze7898
@richardbreeze7898 Жыл бұрын
Can we avoid costs and just take Turmeric with black pepper ?
@corpusarmatae8541
@corpusarmatae8541 Жыл бұрын
The conclusion made me curious. Has there ever been a nutrient/supplement shown to be a good alternative to medication, actually ? I can't think of any whatsoever.
@ps7797
@ps7797 4 ай бұрын
I know I'm not answering your question strictly speaking (like a 1 for 1 swap of curcumin for metformin), but there are examples where meds might be eliminated in lieu of non-phamaceuticals. Exercise has tremendous anti-depressant effects over many drug treatments. Or changing what you eat reversing some metabolic disease when the meds are only managing symptoms. (I'm not against meds, but they aren't the only answer... Though sometimes they may be). I'd rather take turmeric instead of ibuprofen. But if the pain is bad enough, I'll take it or acetaminophen.
@GiorgiGioshvili
@GiorgiGioshvili 8 күн бұрын
Is there any study comparing cooked tumeric vs. powder vs. supplements?
@herbertvonsauerkrautunterh2513
@herbertvonsauerkrautunterh2513 9 ай бұрын
But how much to take ava what type of supplement?
@grantlawrence611
@grantlawrence611 4 ай бұрын
That was funny...900 percent
@tonykhoury5522
@tonykhoury5522 10 ай бұрын
Ok
@BaneTrogdor
@BaneTrogdor Жыл бұрын
How much turmeric powder to replace turmeric supplement ? :)
@littlevoice_11
@littlevoice_11 Жыл бұрын
Do you worry about the oxalate amount?
@mats8038
@mats8038 9 ай бұрын
I take some Tumeric evry day a table spoon in my lemon drink with some garlik and oliv oil and blackpepper( lowered my blod pressure) it do not do anything for my bloodsugar levels they are the same, Normal, but it does help with two fingers on right hand. If i stop taking it i get some pain back in them and i have stopped many times mostly because Tumeric taste like shit so i skip it and then after a couple of days i get pain back in my two fingers. My wife however have another response She have twice as high bloodsugar levels as me normally but they go down to be the same as mine when she takes it. I got her some berberine a couple of weeks ago and she is of Tumeric will check Her blood sugar and see if it works as said.
@mbustube1
@mbustube1 Жыл бұрын
Driving me crazy trying to figure out who this young man reminds me of. Hazard of old age--everybody looks familiar. Great content.
@bp56789
@bp56789 Жыл бұрын
3brown1blue?
@LoveLove-qm6ye
@LoveLove-qm6ye Жыл бұрын
A young Clark Kent
@mbustube1
@mbustube1 8 ай бұрын
He looks like my nephew. I'm 67 years-old and have this problem as well. Everybody looks familiar.
@sabincioflec8413
@sabincioflec8413 Жыл бұрын
It's very good when you are hangover, uhm...a friend told me that, i know alcohol is bad for you. Do you know what the normal dose should be and if more is better?
@dougprentice1363
@dougprentice1363 Ай бұрын
Ive had kidney stones. I know tumeric is high oxilate. Is curcumin suppliment high? I can't find any info.
@grainiac7824
@grainiac7824 2 ай бұрын
Did he give recommendation on dosage?
@AdrianButler86
@AdrianButler86 Жыл бұрын
Which form most bioavailable.? Phytosome? There are a few patented and or trademarked ones.
@littlevoice_11
@littlevoice_11 Жыл бұрын
I wonder if there is a synergistic effect of having the curcumin in the wholefood turmeric form rather than isolated curcumin?
@eliseville
@eliseville Жыл бұрын
Turmeric has multiple constituents. Curcumin gets most of the cred, but I also believe the total complex is more helpful.
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