No guarantees i'll be successful in making pyrimethamine but i'm going to give it a try.

I find your level of information and professionalism just awesome! Keep up the good work!

great score on the glass dude! I also want to thank who donated it to you!! you have tought me alot, so the more equipment you have the more you can teach us!! i didnt get much change from $1000 for mine... Love all your vids!! :D

Salt is a devilish thing to crystallize; it has a strong tendency to form stepped crystals no matter how pure it is. The only solution I have found is to evaporate the solution *very* slowly, in my case by leaving it in a closed cupboard over the winter months. I suspect this is an intrinsic property of sodium chloride since a number of other chlorides formed perfect crystals with much less fuss. (For comparison I had an easier time growing lead iodide crystals.)

You are very knowledgeable and have obviously educated yourself as well as conventional education at my next opportunity I will help fund your endeavors. Hats off

Just to attempt to make some amount of pyrimethamine is such a bad ass idea! Man your videos are awesome, I can't wait for the ones about setting up your own lab come out.

Wow, this is still timely in regards to how science is treated by politicians!

awesome channel great vid as always NR good job !

Fantastic place to start the journey.

Please make a video on a few common battery types along with a few you personally like, detailing the chemical reactions in the batteries. That would be amazing.

This individual's glassware looks very very familiar, and the timing of the donation is also very perfect, so i think i know who the individual is :) But, as you said, we shall respect his or her privacy. Whether I am right or not, I do thank you both endlessly for your contributions to the field; they are certainly appreciated!

im so happy about the amature lab series

Love what you said about batteries vs fuel cells - amazing insight 7 years ahead.

Sweet!!! that's a dope idea for a series.

If I recall my LED theory, the reason that they do not work well for charging photo-luminescent materials is due to the colors produced at the photo-junctions and how the photons are utilized. With white LEDs, the semiconductor materials blue or ultraviolet photons. For the diodes producing blue light, some of it is emitted and the rest strikes phosphors that emit yellow light. This combination of blue and yellow produces a rough approximation of "white". For the LEDs that produce ultraviolet light, essentially none of the UV escapes the LED lens, which is coated with various phosphors to produce various colors of light - usually red, blue and green which the eye interprets as some sort of "white" .

Scoot Malcheski, you the real MVP man!

Thank you very much sir .

very interesting . i like the videos even though i understand very little except the basics , i am 13 . i do enjoy these ones . wondering if you can make a video on carbon based on alkanes , alkenes and alkynes and other carbon compounds . i think you know organic chemistry very well as anyone learning chemistry will tell you , i have an aunt in america working for a famous company starting with something in AS , i dont remember but i love chemistry and keep up the great work , and i hope you make stuff frequently . sorry if this was long .

Dr. N. Butyl Lithium, what glassware suppliers would you recommend a beginner hobby chemist shop from? Also, in regards to simulated reactions, I'm sure that quantum computing is what will ultimately allow us to fully and accurately simulate chemical reactions.

Hello Mr NurdRage Just watching this vid now, and at 5:50 (approx) you described your work as PhD, and myself, as a former biochemistry student turned into organic chemistry, got my ear on you, since enzyme mimicry is one of my favourite fields of research, just because, damn... We have such a lot of naturally occuring products with pharmaceutical interest ,such as ergot alkaloids, THC, psilocybin(wich is set to be produced by genetically engineered microbes), taxol, digitalis cardiac glycosides, and much more, and thinking that all that complex molecules were being made by natural sources using enzymes as catalysts, i would love to see more enzime mimics (such as mimics of enzymes involved on the biosynthesis i referred) being developed for use as catalysts on organic chemistry and pharmaceutical productions Hope an answer from you NR

Whoever donated all that glassware was very very cool indeed... Thumbs up, high five, or whatever salute is applicable to your culture.

The difference in difficulty with growing sodium chloride crystals over those of alum and copper sulphate is that the solubility of sodium chloride increases much less with temperature. Thus if you are getting large (but irregular) crystals using the exact same method as that of alum or copper sulphate, it is likely that most of the crystal is not from sodium chloride.

please do more organic chemistry! I would like to see lutidine and denatonium synthesis. Maybe some dyes too (diazo dyes should be pretty easy) I also have a question: If you do a very complex organic reaction with low yield (e.g. 25%) or with very complex products (disqualifying distilation and making solvent extractions hard to optimise) or both, how do you separate the products and obtain reasonable purity for next steps of synthesis? Also, could you do a How-to video on designing an organic synthesis pathway? I try to design some of my own (with no ability to try out) and I feel like I'm overusing grignards especially in conjunction with epoxides. Another question: can you O-alkylate product of grignard reaction before acidic work-up (magnesium halide alkoxide)?

I have two questions, and hopefully you'll do me the honor of answering both. First, why is it that so many organo-metallics spontaneously combust? Especially the methyls. Why, for instance, does Methyl Aluminium burst into ravenous flames as soon as it's removed from the container? Secondly, what is it you're making in this video? Thanks. Roger

im having a chemistry competition soon and I wanted you to tell about: Suboxides,superoxides and peroxides , please:-)

Further advances in quantum computing should greatly help with predicting and simulating chemical reactions.

Good choice, Scott!

Couldn't agree more with the answer you gave Danny Chan (8:37)

Your content is so satisfying!id be so willing to be a patron for 1000/video if I had the cash

Dear Nurf Rage, Thanks for your educating videos, I was wondering if I can use reverse osmosis membrane as electrolysis membrane

hey Nurdrage... ive been a huge fan for a long time now and I love chemistry and engineering. I am a senior in HS and applying to universities as chemical engineering as my major. Needless to say I think I will like chem engineering and I know the vast differences (between that and chemistry) So my question is where did you go to study and what actually did you study in college? You got your PHD doctorates degree right? How long did you go to school for? I have a lot more questions so if you can shoot me back please!!!! Well thanks so much NurdRage you've sparked many interests in me and I hope to be half the chemist you are one day!!!! (I have a lab set up at home and I do a lot of your experiments :) )

Thank you so much for these videos! I'm 52 and still have that curiosity just like when I was a young boy. I recently started studying Biology, and that led to the Atomic level which pulled me toward Chemistry. Funny how my OCD mind goes where it leads me. If I hit the Lottery, we will make a pure research lab. Because I will invest my money to live on, and the rest we can do Science for the purity of it. Good comments on the way things are. Money drives EVERYTHING now more than ever in history, and I feel it limits us severely in all aspects of our lives and our future. It also drives the Stupid people (those that run with discoveries and feed off of the unknowing) to start making claims that are only half truths and coming up with a money making scheme based on their quack science. So I've discovered in my own studies. Google "find out your lifespan by telomeres" This is BS at its finest. Anyhow..."End Rant" Thank you for the Nerd Porn!! I appreciate your videos, and commend you on admitting when you make a mistake. (We are only human, it's all good) I work with so many people that cannot ask for help, or admit their mistakes. Sad Really.

I want to know, even though you focus more on chemistry and this is astronomy, but what is your opinion on white holes

This comment section...50 people thinking they are clever for mentioning breaking-bad or methamphetamine. People, meth really isn't difficult at all to make. The difficulty in making the mythical super high grade meth isn't so much that you need some super-special recipe to do it or some magic technique; that was just a plot device in the show. In truth, as is the case with quite a lot of chemistry, there comes a level of purity where in, getting it more pure involves doing financially unwise things, like expending more energy in larger and more complicated distillation methods; or letting more and more of your feedstock go to waste because the stuff doesn't end up on the purified side of your apparatus. I presume this is why Nurdrage isn't going to bother to produce medical-grade stuff in his upcoming series. That last level of purification and analysis is pretty dry time-consuming work, and wouldn't make for terribly good videos.

a couple year back I had found a condenser like the one a the star of the video in a flea market but the one i found some kid had decided that if they smash the top it would make a great one off bong if there something that can a amateur chemist cringe specially when you learn the price of a new one

will you ever do a video on aluminum anodizing.

Wow, learning alot even from a Q & A. Also, do you mind if you could make your voice a little higher? I know you are trying to hide your identity, but can you make it just a bit higher?

Speaking of computational chemistry, have you seen Dr. Christian Schafmeister's molecular Lego?

love the vids

I have noticed that shining a red diode laser on green glow in the dark material causes it to darken where the beam hits. I assume it's some quantum mechanical process but could you explain it in detail? Does it have any practical use?

I have a question: Apparently methanoic acid can behave as an aldehyde because it can be thought of as having a CHO group. Does this mean that methanamide can exhibit aldehyde-like chemical properties since it also has that CHO group? Do they undergo all the reactions like any other carbonyl compound would?? (like reaction with 2,4 DNPH etc.)I'd be so glad if you could answer this because this has been bugging me for a long time and i haven't been able to find the answer anywhere else. Thanks in advance!!(i'm reposting this coz it seems like you missed out on this one:P)

Hey anon you rock!

good stuff, keep it up

I just want the basic things for soxhlet extractor and and distillation apparatus for separating solvents from materials to reuse it

I'm not sure that the portland cement answer applied to portland cement. It seemed to explain what concrete was & how it became concrete, but portland cement is like a glue that is used for many masonry materials, not just concrete. I'm not sure that that was accurately answered or explained. Concrete = Rock, Sand, Cement (portland), & water, in large quantities it comes in a truck with a big drum on the back. Portland cement, in large quantities, probably comes from a train car or 55 gallon drums. There is a difference.

Regarding fuel, cells the unfortunate property of platinum that makes it an amazing catalyst in fuel cells and other things is it's atomic radius. The usual failure Mode for Platinum catalysts is causing a reaction so violent that the platinum is expelled from the system with the products. Unless we find a catalyst that operated on a different principal or is significantly less susceptible to passivation platinum will likely be a limiting resource for humanity.

Have you ever tryed to use titanium coated drill bits for electrolysis

Hey my question is very urgent.... Can I use leather gloves in handling sulfuric acid

... That container on the mixer in the background, not being centered, is messing me something fierce man...

Does electrolysis break different or all chemical bonds at certain temperatures of a complicated molecule ?

Setting up an amateur lab? Is someone going to be "Breaking bad"? My questions 1. Is it possible to create a plasma effect using chemicals? 2. Considering 2nd law of thermodynamics is, if organic molecules can evolve in complex entities over eons of time, how do you conserve the 2nd law, i.e., decrease in entropy leads to increase in entropy to balance the equation. 3. how do you integrate quantum mechanics into your modeling of reactions?

Hey could you point "swim" in the right direction in making his own synthyroid ?

9:24 You can blame that on the "scientists" (almost exclusively in medicine, psychology and sociology) who publish fraudulent results.

I have some goggles made of PVC (Polyvinyl Chloride). I need to reshape them, I'm trying to find a chemical method instead of boiling water. I've tried heat but the material becomes brittle and cracks. I didn't see any phthalates last time I went to home depot. Or how do I make methylene chloride? Thanks.

Would your answer to the question about what you would research given unlimited money have been different before you became youtube famous? Or have you always had this inherent drive to educate freely?

if i were a research chemist, i would spend every day trying to discover more less addictive pain relief for the millions of chronic pain sufferers. I have had severe chronic spinal pain for 30 years and there are many who spend most of their life in pain.

Can any one tell me what solutions would be the best to carry out a recrystallization of impure potassium hydroxide?

Could you write a list of the basic things you need to buy to set up a lab 4 basic things obviously you use most of the same equipment in your videos

What is being stired in the background?

If you use table salt for growing salt crystals, use kosher salt instead of normal iodized salt or you'll have sodium iodide contamination, kosher salt does not contain iodine.

I think you should join kahn academy youll have a lot of supporters I think

I teach in a school in Lebanon and we have a lot of the expensive chemical you talk about... If you were closer I would invite you to use the lab.

There are a bunch of other big technical hurdles with fuel cell cars that will probably never make hydrogen fuel cell cars possible; or we need to find some fundamentally different ways of doing things (like higher QE catalysts). Most importantly and primarily, the thermoneutral voltage of water splitting is 1.48V while the splitting potential is 1.23V. Long story short, this means in order to both produce and consume hydrogen, the difference is necessarily converted into a phonon (=heat), which reduces the maximum fundamentally possible cycle efficiency to (1.23/1.48)^2=69%. For current tech low-temperature (=immediately available, efficient) fuel cells, this excess heat needs to be quickly removed at low temperature (about 60C) in order to keep the reaction going, which puts a lower bound on the volumetric power density of a fuel cell. This in turn affects what catalyst complexes you can use and how the supporting pipework and electronics need to behave, which leads to a bunch of problems including the inability to quickly throttle (due to the speed of diffusion of protons), a quite significant loss of hydrogen through the tailpipe which needs to be regenerated and problems with electrode poisoning. In short, PEM fuel cells are giant engineering compromise and having worked with them I just don't see this happening. We need something else. I'm much more interested in autocatalyzing SOFCs (which you can feed pretty much any hydrocarbon), but these have no efficiency benefit over ICEs. Besides, there is no hydrogen infrastructure, there is not enough platinum and palladium and there is no way to fix these societal issues in time before battery electric vehicles outcompete both fuel cells and ICEs.

They say that Toyota fuel cell, use electrolyte to draw electrical power from chemical reaction of hydrogen with oxygen. This electrical power must be huge. So there is a way to capture that enegrgy from oxygen and hydrogen reaction. This is very interesting. Obviously industry dont want peo0ple having something that would not require profit, but I am curious for this technology for long time now. My idea was to use pressure from same reaction and use turbine to convert it to kinetic then electric energy but this Toyota cell dont have any moving parts except compressed hydrogen.

can you make termite whit Al replaced whit chroom?

i am kinda sad the owner of the glasswhere quit but i am sure you will put it to good use

Very interesting

+NurdRage I recall research using Carbon structure as replacement for platinum, from what I recall, it has quite a lot shorter life than platinum but works as well and well Carbon is everywhere so it should be vastly cheaper, cheap enough to make it a replaceable item in fuel cell car. While googling, I found this site, but youtube does not allow me to paste anything apparently. Typing it out, hope I get it correct. Http://www.gizmag.com/nanorod-catalyst/23090/ There is another using polymers but url is much longer and I am likely to make a typo somewhere.

Lysergic acid diethylamide?I've done quite a bit of research on LSA from Morning glory seeds but they contain other chemicals that are poisonous and can cause sever cramps and vomiting not to mention diarrhea, I've heard about people eating the seeds or grinding them and using cold water extraction but I have a bad feeling about LSA, is it possible to extract just the LSA without any of the other chemicals that can cause the number of things I have listed?Also is it even potent at all?

YAY HES GONNA SHOW US HOW TO MAKE CRYSTAL METH!!! :D

That Sodium Crystal guy should try Dishwater Salt that is much more clean than normal Table Salt.

The Tesla cars "Slowly taking off". I'd say they're taking off quite quickly, faster than a Bugatti Veyron! (Pun city!)

where can I get and what would be the most suitable equipment to produce 30% hcl in laboratory on a small scale of 2 liters jeovanny

would be interesting to learn something about nitro glycerine , what it is, how it works and how its done ^-^

I have UV light not bigger than a bean but it's scary; quartz glass all assembled on stainless steel... Scary

Can you reproduce Hennig Brand's method of making white-phosphorus by distilling urine. We've probably all seen it before, but distilling urine and thinking of Brand's neighbours is always good for a laugh.

im almost positive that NurdRage is TAOFLEDERMAUS

sounds like you thought of a use for the quantum computers.

So they named the car the Toyota Future

NurdRage lives in Québec? :-0

sodium chloride is a pain just getting out of solution by evaporation solubility is just so high it's not cool getting out if solution without evaporating some 80% of the water and growing crystals is pobably even worse potassium chloride is much nicer

i love you

Nice glassware. So your new leading benefactor is ... Walter White?

Well,Here's My Dose Of Science :)

wait a month until you get paid for the video series ;)

Many of the questions this month were so damn dull. Someone should ask him how is babby formed or how girl get pragnent. You know, some dank shitblike that.

Its BTTF Day!!!

Question. Whats with the voice synthesizer?

not as an insult, but this isnt your real voice is it? so could you reveal your real voice? ;P

I have just read this week about a nitrogen doped, graphene cobalt catalyst that was discovered to be comparable to platinum in the splitting of water to hydrogen and oxygen. The article explained that this compound could eliminate the need for platinum in fuel cells. Does this discovery increase the viability of fuel cell technology for applications such as automobiles? Was the expense of Platinum the main reason you believe that fuel cell technology will not be the future of automobiles? I have included a link to the article that announces the discovery of the properties of this new compound. Thanks, Daniel Nusbaum www.sciencedaily.com/releases/2015/10/151021115126.htm Chem Student

hmmm ''correct me if im wrong'' and then a very personal answer to a very personal question dosent make much sense

the guy who gave this glass ware probly had a meth lab

Hello

Id like to make a donation of 50.00 if i can ask a few questions about oxides and alumina will you help me.

Can someone donate glassware to me... pls

Are there any interesting reactions with mercury metal?

The glassware probably came from a meth lab who else would want to donate that much, its heavily used, and he wanted to be anonymous. meth lab confirmed

Please go to bed. It's late.

6:18 They don't? What are research grants for?

All that glassware must've came from a meth lab.... No reasonable person would donate that much.