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Ramachandran Principle: Protein Atomic Clashes vs. Phi & Psi

  Рет қаралды 88,042

Eric Martz

Eric Martz

Күн бұрын

Animated atomic models illustrating Phi and Psi dihedral (torsion) angles in proteins, and how atomic clashes make certain angles impossible, favoring the secondary structures of alpha helices, beta sheets, and turns. Clashes are shown forming in real time as phi or psi rotate. Related resources:
-- Quiz (9 questions): proteopedia.org...
-- Slideshow: tinyurl.com/Ram...
-- Interactive 3D tutorial with rotation controls:
-- bioinformatics.... or
-- proteopedia.org...
-- Other Ramachandran and Phi/Psi Resources: proteopedia.org...
EN ESPAÑOL:
-- Cuestionario: proteopedia.org...
-- Presentación: tinyurl.com/Pri...
-- Otros recursos: proteopedia.org...
The RAMACHANDRAN PLOT shown excludes glycine, proline, and pre-proline. Those other plots are available at en.wikipedia.o...
Also recommended: Understanding PHI and PSI Angles, Ramachandran Plots, & Newman Projections -- • Understanding PHI and ...

Пікірлер: 124
@marksteve8373
@marksteve8373 5 жыл бұрын
The best Ramachandran plot video out there! Many thanks!
@singing.winnie
@singing.winnie 4 жыл бұрын
Wow. Just wow. I’ve been struggling to imagine these angles with my head nor by looking at the textbook. This solved the problem!!!!!!! Thank you so much!!!!
@ericmartz9100
@ericmartz9100 4 жыл бұрын
Thank you Winnie. So glad it was helpful!
@leahdavis6265
@leahdavis6265 3 жыл бұрын
I just want to say here because I don't think this is mentioned enough but this video is perfect for visual learners and especially students with ADHD. This is definitely the best ramachandran plot video and visualization I have seen! P.S. I am a BME PhD student with ADHD who came in with a non-biology engineering background currently thrown into graduate biochemistry so if this 1 video can bring a part of an entire biochem course chapter together then you deserve to know how awesome this is!
@ericmartz9100
@ericmartz9100 3 жыл бұрын
Thank you so much for your insight about ADHD learners, Leah. Good luck with your graduate work!
@abhishektripathiii
@abhishektripathiii 5 ай бұрын
True :)
@nancysong9581
@nancysong9581 4 жыл бұрын
The first time I actually understood Ramachandran plot and the phi and psi angle!!! (I first came across it during first year uni and now I have graduated) It's so hard to understand without animation. Thanks a lot!!!!!!!!
@shivi3132
@shivi3132 Ай бұрын
Thank you so much for making this, i was beginning to think id never understand phi and psi angles, after your video i was left wondering why i thought i couldnt
@nabarunr3
@nabarunr3 3 жыл бұрын
Noting but gratitude to you, SIr. And the best part is you enable teachers to present this material, and they can choose not to mention your name. This is truly what open knowledge is, and it cannot come from small minds. I'll strive to achieve this kind of mindset. Thanks a ton.
@ojaswibiswas6
@ojaswibiswas6 4 жыл бұрын
I never understood this concept so well. Thank You so much this is the best possible explanation.
@ambar9232
@ambar9232 4 жыл бұрын
Great explanation and the best thing about it is the 3D Animation which sets it apart from the other videos.
@rialc6238
@rialc6238 4 жыл бұрын
The visualizations really helped understand this topic. This is just what I needed. I wished textbooks would have explained as you did. Thank you sir!
@m.t1446
@m.t1446 5 жыл бұрын
Best explanation of Ramchandran plot on youtube. Bless your soul!
@jessicalv6442
@jessicalv6442 9 ай бұрын
Can't live without this video! Saves my life thanks!
@teresavillalaz1779
@teresavillalaz1779 2 жыл бұрын
I've read infinity of books and nothing was better explained than this! Great work, keep it up!
@kiruthikabalasubramani8874
@kiruthikabalasubramani8874 3 жыл бұрын
It can't be more better than this explanation...I struggled imagining all those angles.. Now I got it...Thank you sir
@Tanya-xl3oy
@Tanya-xl3oy 5 жыл бұрын
Wow. this video was perfect! i can confidently say i understood everything in this video having no prior knowledge. thank you!
@okpolihenry983
@okpolihenry983 3 жыл бұрын
OH MY GOD , JUST WOW . I HAVE BEEN STRUGGLING TO UNDERSTAND THIS TOPIC FOR DAYS UNTILL I CAME HERE . THANK U SO MUCH
@sarahihernandez5434
@sarahihernandez5434 3 жыл бұрын
I was completely discouraged because I wasn´t unable to understand this but now I realized how it works, thanks a looooot! Cheers from México.
@ericmartz9100
@ericmartz9100 3 жыл бұрын
You're very welcome! Glad it helped!
@nanosciencebyjalal3793
@nanosciencebyjalal3793 5 жыл бұрын
it's not fairrrrrrrrrrr , your channel must have millions of subscribers, you are a genius
@Erik-um7hq
@Erik-um7hq 4 жыл бұрын
A fantastic an easy to understand illustration. Good Work!
@helenc40
@helenc40 Жыл бұрын
I understand Phi & Psi at last. Thank you! This is the best explanation I've seen.
@soumilibera8282
@soumilibera8282 3 жыл бұрын
The best video on Ramachandran Plots . I really want to thank you for this. I was really struggling with this . Thank you so much
@neellohitsarkar9183
@neellohitsarkar9183 3 жыл бұрын
@Eric Martz lifesaver!
@sameloliveira6169
@sameloliveira6169 Жыл бұрын
Thank you, my teachers could never explain it better.
@Biocreator
@Biocreator 3 жыл бұрын
best Ramachandran plot video on youtube
@subha_jit_roy
@subha_jit_roy 7 ай бұрын
Best explain video in youtube after saw many video
@nanosciencebyjalal3793
@nanosciencebyjalal3793 5 жыл бұрын
it was the best of Ramachandran i've ever seen
@shruti.7660
@shruti.7660 2 жыл бұрын
Thank you. I was so confused with the understanding of phi and psi angles
@spkm4tube
@spkm4tube 3 жыл бұрын
I hope, my teachers had this kind of tools and willingness to make this concept so much clear. BUT I WILL SHOW THIS TO MY STUDENTS AND TRY MY BEST.........
@qn9cmo0kjoi9
@qn9cmo0kjoi9 2 жыл бұрын
Thank you sir so much for making this video! It's the best on KZfaq. So nice and clear! Big thanks from Taiwan. May God bless you and your love ones!
@vahid8050
@vahid8050 2 жыл бұрын
Very interesting and clear to understand, thank you.
@joshuawhittick4496
@joshuawhittick4496 3 жыл бұрын
great video, love the visualisation of steric clashing
@javaidchoudhary4653
@javaidchoudhary4653 5 жыл бұрын
I watched lots of videos on Ramachandran plot but none of them make me understand . Thanks a lot sir for this well explanation. Plz make some more videos on protein structure and chemical bonding we shall remain thankful to you
@auroshikhamohanta1087
@auroshikhamohanta1087 2 жыл бұрын
This video is amazing to correctly imagine the rotation of torsion angles. It really helped a lot. thank u so much for making this video.
@giammarcoferrari1738
@giammarcoferrari1738 3 жыл бұрын
Thank you very much. I have no other words.
@ionapay6681
@ionapay6681 3 жыл бұрын
This was incredibly helpful, thank you so much for creating this!
@benleohollis
@benleohollis 4 жыл бұрын
4:40 is the most satisfying thing I've ever watched
@ericmartz9100
@ericmartz9100 4 жыл бұрын
Thank you. It was fun to do. I knew for years that it was possible to show the clashes forming dynamically. Since nobody else did it, I finally got around to it.
@slimmathers5665
@slimmathers5665 2 жыл бұрын
WOW. Amazingly done.
@PraneetPaidisetty
@PraneetPaidisetty 4 жыл бұрын
This video made it so easy to understand.
@james4727
@james4727 6 жыл бұрын
the animation makes it so much easier to understand, thank you for the video :)
@mahamali605
@mahamali605 5 жыл бұрын
Best most clear and concise explanation . Many many thanks Sir. :]
@tushardhyani9007
@tushardhyani9007 5 жыл бұрын
Best one on KZfaq for the plot
@Tiago211287
@Tiago211287 3 жыл бұрын
This was an excellent lesson on basic biochemistry. Loved it. Thanks for this.
@siniorashani
@siniorashani 4 жыл бұрын
That was indescribable , thanx very very much
5 жыл бұрын
it's the best explanation about Ramachandran plots !. Thanks ever so much !
@verteeger
@verteeger Жыл бұрын
Thank you for this video with the visualisations and great explanation of what we are looking at! I feel a little bit enlightened :D Thanks again!
@soumendash3911
@soumendash3911 2 жыл бұрын
Hey, I dint know how or thank you this is really amazing I have never seen someone giving a test after a lesson on youtube really happy for that Nice explanation too. Good start to my day.
@yongshancelinene-eh1165
@yongshancelinene-eh1165 2 жыл бұрын
What a great video. Thanks for the content
@mvcnj9700
@mvcnj9700 4 жыл бұрын
Really the best video help visualizing the dihedral angles.
@00metta00
@00metta00 5 жыл бұрын
Absolutely sublime video; concise and coherent. This has really helped me with my understanding of these plots. Thank you so very much 🙂
@mauriciomrable
@mauriciomrable 5 жыл бұрын
Thank you for this video and all the support material. Amazing!
@vipulkumar7035
@vipulkumar7035 4 жыл бұрын
Very nice video. Keep up the good job.
@2361243
@2361243 4 жыл бұрын
This is truly amazing.Nice animation. Thank you so much.
@suprajaganganapalli5880
@suprajaganganapalli5880 4 жыл бұрын
thank you for the video really helping to understand concepts i have seen many videos and books to understatnd it bu t i felt better
@abhiramips
@abhiramips 4 жыл бұрын
The video is very concise and informative. Thank you for that!
@nataliepopielski1125
@nataliepopielski1125 4 жыл бұрын
Thank you! This clarified much of how this works for me!
@jessicamartins7544
@jessicamartins7544 3 жыл бұрын
Great explanation! Thank U so much!
@anjaligupta6180
@anjaligupta6180 4 жыл бұрын
thank you soooo very much sir...i express my heart felt gratitude to you for making this video....its a saviour....!! thanx a tonn....love from india🙏🙏
@jayamalwanniarachchi1437
@jayamalwanniarachchi1437 4 жыл бұрын
simple and amazing explanation.. Thnak you sir
@janbrezovsky2227
@janbrezovsky2227 3 жыл бұрын
Wonderful work! Many thanks for your work.
@lorbasaurus2000
@lorbasaurus2000 5 жыл бұрын
Great visuals and explanation!
@noorakhtar5536
@noorakhtar5536 4 жыл бұрын
exceptional thank you so much! love the links to resources as well; very useful
@leilariver2036
@leilariver2036 4 жыл бұрын
Enfin quelqu'un qui sait expliquer ce modèle.
@ericmartz9100
@ericmartz9100 4 жыл бұрын
Merci!
@olujideakinbo5094
@olujideakinbo5094 4 жыл бұрын
@@ericmartz9100 An angle is described relative to a reference. When you describe the angle of Phi what is your reference? Also when you describe the angle of Psi, what is your reference?
@amirkiamehr1073
@amirkiamehr1073 3 жыл бұрын
This is awesome !! , Thank you so much !!!
@paulinbarajpillai3569
@paulinbarajpillai3569 4 жыл бұрын
Thank you very much very clear explanation
@elississy177
@elississy177 11 ай бұрын
awesome video !
@mayanksangam9205
@mayanksangam9205 4 жыл бұрын
This is fantastic and really helpful. Thank you.
@saumya4655
@saumya4655 3 жыл бұрын
Ty for the video. The quiz was also helpful!
@bioethno3219
@bioethno3219 5 жыл бұрын
Thank you for this video, I understood this part of my course thanks to you!
@durgamthirupathi1838
@durgamthirupathi1838 4 жыл бұрын
Wonderful video
@majakornaj2264
@majakornaj2264 4 жыл бұрын
great video! really helped me understand the concept. thank you so so much!
@tamer4456
@tamer4456 Жыл бұрын
great explanation thanks a lot.
@b.b.bhattarai9198
@b.b.bhattarai9198 6 жыл бұрын
Good explanation. Easy to understand
@fontexstudios
@fontexstudios 2 жыл бұрын
Thanks for the video Eric. What program did you use to animate the bonds with electron clouds and the clashes? very nice to visualize.
@ericmartz9100
@ericmartz9100 2 жыл бұрын
I'm sorry I forgot to credit Jmol. All molecular graphics were done with it: Jmol.org.
@abhishekchatterjee1709
@abhishekchatterjee1709 5 жыл бұрын
Very nice demo. Thank you!
@sunghjung9621
@sunghjung9621 5 жыл бұрын
Love the visuals
@anupammishra5443
@anupammishra5443 3 жыл бұрын
Good visualization
@gokcezora2575
@gokcezora2575 4 жыл бұрын
Thank you, better understanding now
@narendra5769
@narendra5769 9 ай бұрын
Pls upload more video with animation thanks ❤
@zayilsalazar5749
@zayilsalazar5749 3 жыл бұрын
Thanks, I finally understood it!
@geetarautela1
@geetarautela1 5 жыл бұрын
Nice explanation👍👍👍👌👌👌👌☺️☺️☺️☺️thank you sir
@vanessakeating
@vanessakeating 5 жыл бұрын
Awesome video!
@arefsalehi2821
@arefsalehi2821 3 жыл бұрын
That was amazing!
@michellearchuleta7881
@michellearchuleta7881 5 жыл бұрын
Amazing video! Thank you.
@johnl6361
@johnl6361 5 жыл бұрын
Thank you so much for this video!
@amirkiamehr627
@amirkiamehr627 5 жыл бұрын
So helpful especially the simulation
@goliadkin830
@goliadkin830 6 жыл бұрын
Very good explanation! Thanks!!!!!
@damh7621
@damh7621 4 жыл бұрын
Super helpful! Thanks.
@KidScipio
@KidScipio 3 жыл бұрын
excellent
@bikrammajhi7278
@bikrammajhi7278 3 жыл бұрын
thank you sir
@kuberansankaraiyah2558
@kuberansankaraiyah2558 Жыл бұрын
Thanks
@sofiapallais6479
@sofiapallais6479 4 жыл бұрын
Excelent! Thank you so much!
@Proton727
@Proton727 4 жыл бұрын
Re fachero wacho
@navidhoseini8680
@navidhoseini8680 5 жыл бұрын
thanks you very much. the best explanation...
@JP11994
@JP11994 5 жыл бұрын
Amazing explanation thank you
@anjaligupta6180
@anjaligupta6180 4 жыл бұрын
hello sir i didnt get just one thing - in the graph psi is fixed at -165 ° it should occur on x axis and angles -70° to -170° should be the range on y axis n where phi is fixed at -80° it should cut through y axis ... right plz enlighten me with the solution to this query...!! thnk u
@user-sm3oq4lc9f
@user-sm3oq4lc9f 5 жыл бұрын
thank you so much. it was very helpful.
@Kaur_2343
@Kaur_2343 2 жыл бұрын
Mind blowing😱😱😱😱😱
@olujideakinbo5094
@olujideakinbo5094 4 жыл бұрын
An angle is described relative to a reference. When you describe the angle of Phi what is your reference? Also when you describe the angle of Psi, what is your reference?
@brnkaik
@brnkaik 4 жыл бұрын
Thank you very much!!
@marcogrilli1850
@marcogrilli1850 4 жыл бұрын
I psi e phi dello stesso amminoacido ma che appartengono oramai a 2 piani peptidici diversi adiacenti
@MrMigzz29
@MrMigzz29 3 жыл бұрын
Amazing!
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