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Randy Schekman and James Rothman were awarded the 2013 Nobel Prize in Physiology or Medicine for their work on elucidating the components and mechanisms of the secretory pathway. In an interview with Ron Vale, Drs. Schekman and Rothman talk about their early careers and the key experiments that led to some of their most significant discoveries.
Speaker Biographies:
Dr. Randy Schekman is a Professor in the Department of Molecular and Cell Biology at the University of California, Berkeley, and an Investigator of the Howard Hughes Medical Institute. At Berkeley, he developed a genetic and biochemical approach to the study of eukaryotic membrane trafficking. In addition to the Nobel Prize, Schekman has received numerous honors and awards including the Albert Lasker Award and the Louisa Gross Horwitz Prize. He is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. Currently he is Editor-in-Chief of the open access journal eLife.
Dr. James Rothman is the Wallace Professor of Biomedical Sciences and Chair of the Department of Cell Biology at Yale University School of Medicine. He uses biochemical and biophysical approaches to uncover the mechanisms involved in vesicle trafficking and vesicle fusion. In addition to the Nobel Prize, Rothman has received many awards and honors for his work, including the Albert Lasker Award, the Kavli Prize for Neuroscience, and the Louisa Gross Horwitz Prize. He is a member of the National Academy of Sciences and Institute of Medicine and the American Academy of Arts and Sciences.