15 years after upload, this are still the best tutorials you can find on youtube and they save my a** often during first year of med school. Thanks for ur videos, not all heroes wear capes!!

I freaked out when you said don't freak out, always a precursor for bad news.

Can you please do an update of this where you differentiate between the six layers of cerebral cortex please?

Thanks ! This video is very useful to me but i still have the problem with the identification of other cell types in brain tissue like macrophage or PMN in the inflammatory response

how do you differenciate the 6 layers?

Thank you very much. :)

@darlantro Just to add a little more explanation... The blood brain barrier was discovered by Ehrlich who injected dye into the blood and noted it didn't reach the brain, later one of Ehrlich's students injected dye into the CSF and noted the dye didn't reach the blood. (Much) more recent repeats of this second experiment with microscopy show that the endothelium of blood vessels in the brain, not astrocytes are the barrier, as the dye in the CSF reaches the endothelium but not through it.

Dr. I’m here… a medical student from 2023

Dear sir please give some pointers to differentiate low grade glioma vs reactive gliosis

Is this from the Iowa set on the biolucida program?

Sayonara!

@radium86 This is correct: to be specific, endothelium is the blood brain barrier. The role astrocytes play in the BBB is their foot processes induce the cells of the endothelium to form the tight junctions that make up the BBB. So if asked "what makes up the BBB", the answer is endothelium, but you should also be aware that astrocytes play a role in it as well, though it is indirect.

A little correction, the meninx is the dura mater, not the arachnoid

One part of my histology-exam is a slide test, and if I pick Cerebral cortex I must distinguish the six cytoarchitectonic layers.. Do you have any tips on how I can tell the difference between them?

almost freaked out...

Thank you Sensei, and sayonara😁

Cool video! A lot of those small cells are endothelial cells forming vasculature... maybe worth pointing out that they are non-CNS but still in your slice. Also, there are smaller neuronal nuclei (for sure in layers 2,3 & 6of the cortex) so generalizing that all small cell nuclei in an area are non-neuronal is tough. Related note; splitting hairs again, but astrocytes "are the blood brain barrier" is not entirely accurate, in that endothelial cells actually form the blood brain barrier.

Thanks

arachnoid mater is just a layer. the sub-arachnoid space is where all the vasculature is. between the arachnoid mater and the pia mater you will find the subarachnoid space. sorry you never got an answer to this Q for 2 years :(

Brain have more than two types of cells

@Eklipse113 'astrocytes surround the blood brain barrier' is how I would describe the situation; I said I was splitting hairs with that point. (I have a doctorate in neuroscience, specifically related to brain injury).

why is it white around the blood vessel does it have to do with myelin?

Thanks for your videos! Would you mind making a video with you eating a section of unfixed brain tissue?

heeheehee NeurAHn

❤❤❤❤❤❤❤❤❤❤❤

i love you

I'm freakin' out my exams are in month

this channel stole your video as their own if you want to file some sort of copyright infringment kzfaq.info/get/bejne/j8CnqJZ0ubC1pJ8.html

Is this a meningitis case?