Sickle cell anemia - causes, symptoms, diagnosis, treatment & pathology

Рет қаралды 1,090,301

4 жыл бұрын

What is sickle cell anemia? Sickle cell anemia is an autosomal recessive genetic condition where the beta-globin protein subunit of hemoglobin is misshapen, which ultimately leads to a sickle-shaped red blood cell, which is prematurely destroyed and can get stuck in small blood vessels. Find our full video library only on Osmosis: osms.it/more.
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Пікірлер: 440

@Luke-pk3rb 3 жыл бұрын

This video is INCREDIBLY well made. I cannot get over how in-depth, informative, and factual it is while still managing to be so concise. Must have taken so long to make so well done to whoever did. I'd love a list of your sources if that is also possible.

@ashleelarsen5002 2 жыл бұрын

I agree, but what do we use sickles for anymore? Gen Z is only going to know what sickles are for this discussion, they should change it to "crescent moon" disease...

@fidosa8382 10 ай бұрын

@@ashleelarsen5002 bruh we know what a sickle is 😭 hmar

@dinogt8477 3 сағат бұрын

Sickle cell

@sa21539 4 жыл бұрын

If only med school professors taught lectures like this

@prathameshagrawal2437 3 жыл бұрын

He himself is med school teacher biro

@adnaansheik7553 3 жыл бұрын

@Sameer Ahmed I agree with you bro. The ones in my Uni are so boring that you might wonder what the heck are we doing with our life and why we chose Medicine.

@genuine_meteen9169 2 жыл бұрын

Haha...so true, looks like most med schools professors byheart and spit in it in class Without logic.

@someone-jl9fu Жыл бұрын

professors in uni teach like shit they make me wanna kms

@IsmbbailBb89 11 ай бұрын

it's not a professional way of learning even if it's simple you should read and be aware of every little detail , i wonder what the face of medicine with students like you

@gpsrandhawa8117 4 жыл бұрын

It was my Grade 12 final biology practical and my project was Sickle Cell Anemia. I watched this video a night before and it all went so good. The examiner was so impressed. Thank you 😊

@snehas9639 4 жыл бұрын

i am doing the same thing

@the_cracker_boi_4926 4 жыл бұрын

Lol mines 6th grade wow

@malikgaming3655 3 жыл бұрын

i have sickle cell anemia

@sportnewstv2749 3 жыл бұрын

@@malikgaming3655 me too, how are you dealing with your situation 😥

@aishwaryasiva4514 3 жыл бұрын

👏🏻👏🏻

@docsanti8971 4 жыл бұрын

WOW! Very well explained! Wish we had this kind of resources when I was at Med school. Well done!

@faijumusic1599 4 жыл бұрын

Check out my Sickle Cell Disease testimonials ❤️❤️❤️ Please subscribe to my channel!

@otet2004 3 жыл бұрын

😑 omg read the book is much details than this video a lot !! But what i love about the video is so brief and made easy

@ShikaTheGod 3 жыл бұрын

I have Sickle Cell Anemia so I know this is on point, also I haven't had a SCA Pain Crisis since 2012 so hooray!

@SlickEvan 3 жыл бұрын

2012 wow! Nice work!!

@alltalentsmediacrayz2798 3 жыл бұрын

Honey which country are u or please inbox me thanks I need to talk to u

@ShikaTheGod 3 жыл бұрын

@@alltalentsmediacrayz2798 I'm in the US, Texas to be exact

@alltalentsmediacrayz2798 3 жыл бұрын

Wow dear

@alltalentsmediacrayz2798 3 жыл бұрын

Are u on watsup dear

@xsx_kingx 3 жыл бұрын

Thank you so much this video helped me a lot I'm 15 and I'm trying to create a cure for sickle cell this video helped me get a lot of notes and I would love to text you and ask you some more questions

@monoromo 3 жыл бұрын

Good luck on curing it!

@cristamundil6697 3 жыл бұрын

What are you thinking? How’s it coming along? Don’t give up! That’s wonderful

@kimeilacampbell2694 3 жыл бұрын

Thanks! I wish you the best

@everydayshad 3 жыл бұрын

I would like the cure because I’m only 11 and I’m scared of death

@45_dhruvpandya20 2 жыл бұрын

Um I don't know if you're joking or actually serious. You're 15 and anyone can use the famous Phineas and Ferb line of "Aren't you kids too young for all this ?" But good luck to find the cure. I wish you success !!

@LSBUFU 4 жыл бұрын

Incredible lecture for nursing students like me. Thank you!

@BillieB. Жыл бұрын

Very good video, I didn't come here to learn though because I unfortunately have sickle cell anemia. But I occasionally watch these videos when I'm dealing with minor pain as weird as that may sound it's comforting 😞

@osmosis Жыл бұрын

We hope that our video was able to help 🙏🏼

@splendidmercy6567 Жыл бұрын

Thanks so much for the video

@Bassman7608 Жыл бұрын

Just lost a good friend to a sickle cell crisis. This video has taught me more than I could have imagined and I hope I could pass this on to as many as I can

@osmosis Жыл бұрын

We're sorry for your loss, Kevin. 🙏🏼

@RohitPant04 4 жыл бұрын

Thanks for always providing us with extra information on common BioMedical topics like this!

@khushboogupta8083 4 жыл бұрын

Your videos are really a great help in understanding the concepts.

@Tanishdutt0007 Жыл бұрын

I watched Video of Renal Artery Stenosis and made my project of Class 11th And believ me My teachers were so impressed with me. They all appreciated me . But all thanks Goes to OSMOSIS, I LOVE ❤OSMOSIS

@osmosis Жыл бұрын

Wow! That's awesome! Thanks for letting us know, Mamta! 💕

@Tanishdutt0007 Жыл бұрын

@@osmosis Yeah!! but that's my mom' name. My name is KRRISH, by the way I loved you replied me after reading my comment. ❤❤

@anjalieabhayarathne6314 3 жыл бұрын

This was just so amazing! I had no idea that sickle cell disease was THIS easy to understand. It was very very clear. And I love the attractive pictures. And the narration was so good as well. Thank you so much!!!! Keep up the good work! 😁❤

@Afton_OnYoutube 3 жыл бұрын

@Daron Brown Aye, I do too

@patriciacole1117 2 жыл бұрын

No one should born with sickle cell today get tested get tested before you marry or get into a relationship please 🥺

@milonmitra3584 Жыл бұрын

You presentation is excellent. I would like to add one point- the lifespan of normal RBC is 120 days but a sickle cell rbc's lifespan is 10-20 days. This cause increased destruction of RBC with anemia.

@oreskoul 3 жыл бұрын

Great video . Well explained . Made it easy . Once again, thank you osmosis ! 🙏🏼

@mtorabi6266 3 жыл бұрын

Because of your perfect videos now I can learn and enjoy.thank u

@akashkamboj1270 4 жыл бұрын

Sir this is the best video lecture I have ever seen Wish my teacher could teach like you

@hkhk1901 3 жыл бұрын

I wish I had professors like you in university 🌟amaizing job

@mariaalma6563 3 жыл бұрын

Cramming for my midterms right now. This helps so freaking much. Thanks for existiiiing!

@mahimasreehari6216 4 жыл бұрын

It's really very helpful, i was literally confused but thanks to you I got it now . Thank you very much ☺

@legends-og5dx 4 жыл бұрын

@VampireDiariesBiebs 4 жыл бұрын

cant thank you guys enough!

@music_7735 Жыл бұрын

Simple ,clear and perfect explanation !!👏

@osmosis Жыл бұрын

Thanks, Suharshitha! 🙏🏼

@rubasarkez9917 4 жыл бұрын

Well done thank you so much 👍🏻👍🏻

@alexanderksn2372 4 жыл бұрын

Thanks a lot for your videos! Maybe it was worth paying more attention to prime editing or CRISPR Cas9 or Cpf1 as an innovative approach to treatment?

@munahiljaved2028 2 жыл бұрын

Very well explained in a much comprehensive way!!

@osmosis 2 жыл бұрын

Glad you liked it, Munahil! 😊

@justsomeguywithsunglasses3661 4 жыл бұрын

Incredible presentation!

@Stubborn214 4 ай бұрын

Hands down! the best lecture on SCD!! It was palatable ❤

@osmosis 4 ай бұрын

Wow, thank you! ❤️

@theenglishfamily5375 3 жыл бұрын

Well appreciated... We look forward to more understandable videos ❤

@clarycluade666 3 жыл бұрын

I was born as sickle cell I pass throughout a lot of pain I thought my life as come to an end. I lost all my hope until a friend recommend me to baba ifa. BABA IFA thank u for my life may God continue to bless ur good work. no more pain or crisis I'm free indeed, U can so give him a try All u need is to believe +234 818 203 5968

@todotvstreaming 2 жыл бұрын

I recently lost a good friend of mine because of sickle desease. She used to have treatment which helped her deal with this disease but she got vaccinated against COVID a few months ago and she started to have more frequent outbreaks. Really sad that she passed away so young, 34 years old. Seems the vaccine increased her risks due to this health condition. May she rest in peace. She was always smiling and happy despite all the pain this sickness caused her 😔

@DavidJohnson-dc8lu 2 жыл бұрын

You saying Covid vaccinations are bad for SC? Vaccinations does inflame the body!

@kevinsteel7875 Жыл бұрын

The editing and transitions are seamless, very nice very informative.

@osmosis Жыл бұрын

Glad you think so, Kevin! 💕

@user-xu8pt6uy8h 2 жыл бұрын

Whenever we need to learn full medical information with fun and short time Osmosis is here to help. Thank you Osmosis from all my heart. I am the first on my college because of u ♥️♥️🎓♥️♥️

@osmosis 2 жыл бұрын

Wow! Thanks for letting us know! Our pleasure to be of help in your studies! 🥰

@zackabdihakim2737 4 ай бұрын

Thanks. Very well prepared and presented.

@justineclark5775 4 жыл бұрын

Wonderful video. Thank you.

@waleedkhalid6908 3 жыл бұрын

Thanks for your wonderful efforts

@omnaik5539 3 жыл бұрын

Thankyou for this important information

@semsem8801 3 жыл бұрын

Thank you for all videos

@reginaopoku2203 Ай бұрын

Splendid ! I'm a sickle cell carrier and this is very educative . God bless you. I'm watching you from Ghana. Wish you the best in life 🧬

@osmosis Ай бұрын

Thank you 🙏🏼

@fasamah.kollie8767 Жыл бұрын

Splendid ❤ demonstration. A well deserved hats off 🙏🏻😊

@osmosis Жыл бұрын

Glad that you appreciate it, Fasama! Thanks! 💕

@Carlos_Jzx 3 жыл бұрын

I have this decease and men o men thanks for the great job on explaining this and this is the best explanation I have found yet!✌🏽

@rajeshwarijessy7776 3 жыл бұрын

Can u explain your symptoms while affected by this decease

@Carlos_Jzx 3 жыл бұрын

@@rajeshwarijessy7776 You really want to know. It's very very detailed here I can't add more is a bit different to some of us on how affects you for example I move to the north east and I been here 16 years and the cold has started to bother me in ways I didn't experience before.🤷🏽‍♂️

@soyyy-saucee3858 Жыл бұрын

@@rajeshwarijessy7776 I have sickle cell and a thing i notice is i cannot take full breaths, my heart races rapidly, and i syruggle to breath when sleeping or laying

@nakayizaneema2264 Жыл бұрын

Sure?

@zzs8948 2 жыл бұрын

Amazing content indeed ! But the type of hemolysis in Sickle cell anemia is mostly extravascular and abit less intra as far as i know , thank alot

@thathappymind6916 Жыл бұрын

Very helpful video ! Accurate and easy to understand

@osmosis Жыл бұрын

Glad you think so! 🥰

@AlexandraAbia 4 жыл бұрын

Thank you, very informative!

@KhadeejaMansour 5 ай бұрын

absolutely helpful, thanks!!!

@osmosis 5 ай бұрын

You're welcome, Khadeeja! 😊

@christinesalami7712 Жыл бұрын

Your videos are my savior in medical school ❤❤❤ lots of love The most wonderful thing that happend in my medical journey is Knowing and learning from your videos love you a lot ❤❤❤❤❤

@osmosis Жыл бұрын

Our pleasure to be part of your medical journey, Christine! 🥰❤️🙏🏼

@belanabdulla6368 4 жыл бұрын

Very helpful, thanx.

@sniyastanlyk7676 2 жыл бұрын

Beautiful narration and presentation ❤.. Loved it ✌

@osmosis 2 жыл бұрын

Thanks a lot, Sniya! 😊

@ismailissifou2024 3 жыл бұрын

this is awesome and really helpfull, but could you be able (or maybe any reader) tell me what source was used for this vid?

@hanrubuhrmann384 3 жыл бұрын

This was a damn masterpiece

@SALMA-mq2os Жыл бұрын

You always save my brain from any additional requirements 😇 thanks

@osmosis Жыл бұрын

Happy to help! 🥰

@nozomiyomi1039 3 жыл бұрын

Wow thank you osmosis.

@danielkq 3 жыл бұрын

Hello from Brazil!

@minaazeez1311 2 жыл бұрын

That was very helpful. Thank you.

@osmosis 2 жыл бұрын

Glad it was helpful, Mina! 💖

@livingdeadgirla 2 жыл бұрын

1:24 I never knew that before watching this. Extraordinary.

@Jeene269 2 жыл бұрын

Thanks for the good explanation ✨

@osmosis 2 жыл бұрын

You’re welcome! 😊

@savannahandrade8188 4 жыл бұрын

Such an informative video

@rahafabdelgafoor4002 3 жыл бұрын

Some informations in the video are correct

@toysfunny6944 4 жыл бұрын

Amazing Job thanks

@worldgreatempire Жыл бұрын

I swear this is great!! Abt Medschool Professors... I suppose it's because we already have a background with Sickle Cell Disease is why it now appears easy... This will be difficult for a newbie! Unless revised over and over

@osmosis Жыл бұрын

Thanks! 💕

@keziahaddoquaye53 3 жыл бұрын

I’m a 14 year old girl who has sickle cell disease that just wants to know more so thank you

@cryptomom3170 3 жыл бұрын

Love it!!

@cryptomom3170 3 жыл бұрын

Well I'm saying. Not that fact u have. I know what it brings my 16yr kld daughter has sc disease. It's just the fact that u want to know more!

@cryptomom3170 3 жыл бұрын

@Daron Brown stay strong! My daughter has SC disease she's not in & out the hospital as those with ss disease... But when she have episodes it's painful! Prayr to you all😘

@keziahaddoquaye53 3 жыл бұрын

Daron Brown stay strong 💪

@vet5838 3 жыл бұрын

@Daron Brown you are a WARRIOR! Praying for you always.

@morrenmbilinyi3545 2 жыл бұрын

Really thanks you,that was so helpful

@osmosis 2 жыл бұрын

You're welcome! 🥰

@TheX7mood 4 жыл бұрын

Outstanding!!

@AfricanAnimeLoverAMV 4 жыл бұрын

Thank you

@sumathybalaji5252 2 жыл бұрын

Very nice explanation

@joang.5174 2 жыл бұрын

Hello, good morning. Thank you so much for wonderful lecture/discussion. Your video so helpful to my course. I learn a lot, can I use some of your video like diagnosis,treatment etc. For my project? @Osmosis

@osmosis 2 жыл бұрын

Hi Joan! Glad that you find our videos helpful. You may reach out to support@osmosis.org and our team will be glad to assist you on your inquiry. 🙏🏼

@srajan_shukla 2 жыл бұрын

Could I please please get the pdf of this presentation.... 🙏🏻 🙏🙏🙏

@japjyotkaurahluwalia8957 3 жыл бұрын

Great job

@srirambhardwaj2343 4 жыл бұрын

Very.helpful.lecture.

@dikshashelar2508 4 жыл бұрын

nice explain

@drlenton1746 Жыл бұрын

thanks this is great workout in few minutes

@osmosis Жыл бұрын

Most welcome! 💕

@user-gp4qg5tk7e 4 жыл бұрын

I love ur videos 🙏🏻

@yaya-fv9eg 6 ай бұрын

Thanks ❤❤

@raicarab5246 4 жыл бұрын

Thank u so so much

@vishalarya5732 4 жыл бұрын

Kindly make videos on gynae

@estiakshakil2663 Жыл бұрын

Excellent explanation...❤️

@osmosis Жыл бұрын

🥰❤️🙏🏼

@mariaragonese2543 2 жыл бұрын

I'm only here because one of my co-workers has sickle cell as well as one of my customers and I want to better service them. The man actually had jaundice and I had asked him if he was okay. He said he had sickle cell and outside of the fact that mostly black people and Native Americans get it I don't know much about it.

@nolapender9239 3 жыл бұрын

This video helps me a lot for my tomorrow’s presentation about sickle cell anemia in rle109

@DT-el3ty 4 жыл бұрын

Very useful

@zaidbasheer9152 Жыл бұрын

I was almost giving up until I saw this vedio ❤ Thank you very much

@osmosis Жыл бұрын

We're glad this helped, Zaid! ❤️

@pgaspirant1228 3 жыл бұрын

Osmosis is the best thing that can happen to a medical student. ❤️

@osmosis 3 жыл бұрын

Thanks for your kind words! Always glad to help you in your medical journey!

@mjk9152 3 жыл бұрын

Thankyou sooo much 💙💙💙💙💙💙💙💙

@enriqueermusmd Жыл бұрын

great video! thanks!

@osmosis Жыл бұрын

You're welcome, Enrique! 💖

@gtgodbear6320 2 жыл бұрын

I have to get for blood transfusion post-op from internal hemorrhaging after getting an appendectomy. Hemoglobin levels just kept dropping and dropping all night. I had to have an emergency surgery and 4 blood transfusions to fill me back up with blood. Doctors were baffled that I wasn't dead. They had to cut me open like an old-time discectomy to find the bleeding and vacuum out all the blood. I had a staple puncturing a small artery at the appendix removal site. Closest I've been to death. Good thing they chose to keep me overnight or I would have died if I was sent home.

@fahadmunir892 2 жыл бұрын

May I ask Please Have you experienced a sickle cell pain crisis (also known as a vaso-occlusive crisis [VOC] two or more times within the past year?

@BillieB. Жыл бұрын

@@fahadmunir892 I have my friend, I also have SS

@MuhammadAshraf-ig1qd 2 жыл бұрын

Informative and impressive Vid ❤️

@osmosis 2 жыл бұрын

Thank you, Muhammad! 🙌

@jigarsolanki2499 4 жыл бұрын

Thanks sir

@BA-vc9wh 5 ай бұрын

Very wonderful and informative presentation 👏 👍

@osmosis 5 ай бұрын

Thank you! Cheers! 😊

@Sarahwilliam455 Жыл бұрын

I totally appreciate this Video, I'm in Nigeria and I was able to get hydroxyurea about two years ago which was really helpful but I've been finding it hard to see it in Pharmacies I'm Nigeria, Can you suggest how I can get this Medicine??🙏🙏 I'd appreciate a response Sir.

@justrandom4304 4 жыл бұрын

Is sickle cell in anyway related to the repetition of getting blood clots coz I have some kind of anemia I just realized that I might have a blood clot near my lungs its a sharp pain when i take a deep breath. I'm going to see a doctor ASAP

@nabukhanal6519 4 ай бұрын

my dad at the age of 70 got diagnosed with this . He had dengue few month back since then he had been sick n tired

@jalilahmadtokhie7805 2 жыл бұрын

Proud of osmosis production company

@osmosis 2 жыл бұрын

Thank you, Jalil! 🥰

@user-ve5wx9lz8g 4 ай бұрын

Well appreciated on well explain lectures

@osmosis 4 ай бұрын

So nice of you! Thanks! 🥰

@JuliaHelen777 4 жыл бұрын

Where on the axis of Hishimoto-Fybromialgia-MS-CFS-Parkinson do Sickel Cell Disease pass in & what might be the interrealtion? What IF is all due to artificial syntetisation of biologic life? Is there any open source study taking this points of view in consideration? Where can I find more?

@patrigodomingo4931 3 жыл бұрын

NICE ONE

@rajeshwarijessy7776 3 жыл бұрын

Tq very much

@billrowe3350 2 жыл бұрын

My beautiful strong wife has Sick cell God bless you all who share this illness our prayers to you warriors!!!!

@fahadmunir892 2 жыл бұрын

Hope she will get well very soon.

@fahadmunir892 2 жыл бұрын

May I ask Please Have your wife experienced a sickle cell pain crisis (also known as a vaso-occlusive crisis [VOC] two or more times within the past year?

@barshaacharya6783 9 ай бұрын

So informative

@osmosis 9 ай бұрын

Glad you think so, Barshaa! 💕

@manikandanbalakrishnan3373 3 жыл бұрын

Have Avascular Necrosis, and having same symptoms of sickle cell disease

@binodadhikari5255 3 жыл бұрын

How sickle cell disease causes osteomyelitis? Any idea plz

@KenzyFarid 2 жыл бұрын

Very Excellent!

@osmosis 2 жыл бұрын

Thank you! Cheers, Heba! 💙

@halicarnassus8235 Жыл бұрын

Sickle cell is not even common in most black Americans , however I had a black American friend who was born with it and she described it as if "Fire running through her Veins". Such Pain. Such torture.