I'm reading locked in. Hopefully i wont be around anyone who rnds up in a coma but if i am i will talk away to them.

I was in a coma on a vent for a week. I remember just a few things but one was a nurse who was braiding my hair too tightly. I could easily have been happy floating in my head for the rest of forever.

@@daniellekenaston9895 Damn that's heavy...seriously though was it truly enjoyable I'm honestly curious.

@ghost mall also didn't have to have degrees like u do now.

Heard a Ted talk about a comatose patient that recovered. I cannot even imagine what it'd be like for them and their family.

Yeh, sounds like locked in syndrome. I've let my loved ones know they need to euthanize me, whether legal or not. It's my absolute nightmare scenario.

Like being a prisoner in your own body. ALS can be like that as well, psychologically at least.

Paralyzed while thinking is the worse. They could not have even moved their eyes to communicate. That is scary. I don't remember if he said they can feel or not. Give me five months and stab me by a shamab, witch doctor or priest with an obsidian blade in some ritual so I can laugh in my head about how crazy life is and my family had it done. No cremation! Make me a mummy with tablets lying in English talking about all the scientific deeds and battles I've fought. So those 2,000 years from now know just what I did. (In 2004 he fought off 2,000 men, and later cured covid. Then went on to make an exoskeleton which basic design is still is used.) Damn I wish I had the money to make something like to prank historians. 100 tablets of granite should suffice. Dunno if memory cards can last.

My father died of ALS (I was his caretaker), the slow progression of conscious paralysis was the worst thing i have ever seen, hands down.

Many people with Myalgic Encephalomyelitis are barely able to move, and from experience, it absolutely sucks. But honestly it's worse when I'm able to do a tiny bit but have to stop due to the pain and fatigue it causes, as at least when I'm unable to move I don't feel guilty for not being productive enough (thank you capitalism).

Yes, it's that way wth all autoimmune diseases too. I've fought for good treatment for 30 years. Drs don't seem to know what to do with it

@@megancrager4397 How much worse does your case make vaccinations? They don't work, or even exacerbate the self-destruction?

Yup, I’m now at 30+ years with CFS & fibromyalgia (as well as several other chronic conditions). On top of that I’m at unusually high risk genetically of developing Alzheimer’s (pretty much everyone on my mother’s side of the family had or has it, most symptoms starting near my current age, 61). I have come to terms a long time ago that I’m not going to live into great old age, and honestly I don’t particularly want to. I measure life by functionality and quality, not quantity-as long as I’ve got enough of the former to get by and have some contentment, fine. But I’ll be damned if I spend years of deteriorating misery unable to engage meaningfully with my own life until my body finally gives out. Can’t think of many worse fates. Totally with you on the living death description; I’ve had long stretches of being bedridden and/or housebound and it’s horrifying. Once heard someone use an old joke to describe it: the good news is, what I have won’t kill me…the bad news is, what I have won’t kill me. That’s pretty much summed it up for me. And I’m just too fucking tired (keeping in mind the difference between ordinary tiredness and clinical fatigue, which is a whole other level so many people just don’t understand) to engage in any activism for research or treatment. What’s coming down the pike with long Covid is terrifying. Maybe when a whole generation are becoming disabled in mass numbers some effort will be made. I hope so.

I’ve dealt with it too (I started Adderall again for my ADHD and that’s helped a lot) and what people don’t understand is… anything chronic fatigue goes so beyond being tired. It’s not “I take a 15 minute nap and I’m refreshed”, it’s laying on the couch for 30 minutes literally being unable to do anything else. When it got really bad I couldn’t even sleep because that required changing into pajamas, setting my alarm, and actually getting up to get into bed. It’s being so tired you can’t even think. Adderall has some awful side effects but I would never go back to being without it.

Same with dysautonomia. I'd never seen it mentioned anywhere apart from support groups until the pandemic. If anything good came out of the pandemic, it gave illnesses like these more mainstream attention.

same here. scary stuff...

Same here!

I knew about this illness and was impressed that Gaiman had done his homework. My maternal grandfather’s 1928 death certificate states ‘meningitis’, but he may well have suffered from the hyperkinetic form as my mother, then only four, could clearly recall the horror of seeing him jerking and making odd noises before he was removed to hospital.

Sleepy sickness can also happen when someone gets a date rape drug.

same!

That is exactly what happened 😂.

And changes shirt

Fat line of coke and onto BB..

Found his lastest channel the other day think I'm subscribed to all 1000 now

Yes.

same!

👍👍👍

Yea i made the same mistake (actually trying to find my comment to someone else about that to delete)

Me too. I just assumed that Simon was talking about African Sleeping Sickness, the one spread by that fly.

So did I. I thought it was the Trypanosoma cruzi or bruci. Apparently there are more than one Sleeping Sickness. Go figure.

What's insane is people call COVID the worst "plague" in history they have literally know idea. I can name 4 off the top of my head significantly worse

@@shadymcnasty5920 Who says that? I've never heard anyone say that. COVID is, however, serious and deadly and should be treated as such.

@@-xirx- I have. Mostly emotional people, or those who aren’t well read. There’s a lot of uneducated people out there.

@@waterloo32594 wow. Very true now I come to think of it.

@@joannesmith2484 I've come across tons of them. There's so many people acting like COVID is going to end the world. It's definitely worse than getting a cold, but it's also not nearly as bad as some of the other stuff floating around out there.

i wish i could i swap anything,for 16 hrs sleep in one night not over one week like normally

@@bobmiller7502 You do because you dont realize how fucking devastating this is to your quality of life. You dont wake up feeling well-rested, you wake up wanting to do nothing but sleep forever.

@@onyxsuccubus personally when I sleep too little I end up falling asleep throughout the day, so no not really

I’m sorry to hear that… How’s he now? I hope you don’t mind me asking… God bless you an your family!

I have narcolepsy and everything becomes x10 more frustrating when you’re chronically tired, I’ve accepted I’m going to be grumpy forever.

@@ScouserLegend I’ve got no sleep illness but I’m a fucking cunt

YES

it does cause personality changes, somehow probably due to mild damage to the brain, i'm not entirely sure

ALS!

He could already do a top 10 of simon whistler channels. He has 11, lol.

Brain (business) blaze is obviously #1

He could do two, one based on subscribers and the other on how much he likes filming it.

@@Cman04092 he has 12, new one debuted yesterday.

I hope he does it on April fools

What was the medical problem you were facing when it happened? I had a friend who said it happened to him when he got an MDMA pill that was later confirmed to have been more meth than MDMA. We don't really talk anymore, but I'd seen him post on Facebook saying he's dealing with retinal detachment now too, which I can't help but feel it probably has something to do with that few days he went through that.

@@ledumpsterfire6474 it was a new antidepressant I believe, I'm sorry but I have already forgotten the name... but yeah! anything that messes with brain chemistry has a decent chance to cause some pretty fucked up things that could be permanent... I hope your buddy feels better soon! it's so strange and frustrating to go though, the eye strain is enough alone but by overflexing the eye muscles I'm sure much worse could happen than just the soreness after 😬

@@ohsaintends I had that horrible side effect too! It was a side effect of an antipsychotic beginning with F. Horrible it was, caused acute dystonia. Happened 20 years ago or so

I have witnessed a family member have this crisis. Never been so scared for them before. I felt very helpless only able to watch and nothing else

​@Purple_Wellies Fluphenazine perhaps? 1st generation anti psychotics are notorious for causing extra pyramidal reactions. At least an anti cholinergic like procyclidine can relieve it fairly quickly these days but unless your doctor is familiar with your med history they'll presume it's something like street drugs, epilepsy or an infection rather than a relatively simple to fix issue. Always good to carry a note to say you're on meds that can cause EPS or have someone close to you aware of the danger.

Thank you for the laugh, even if this is incredibly accurate

In Brain Blaze he is suffering from excessive silliness. Perhaps it is encephalitis.

Holy fuck this is exactly how it went with my boss at one of my first jobs. We're still really good friends to this day lmao

Marching powder

@@2degucitas I wanna know what it is, but I’m afraid to google it… Hehehehe…

I remember watching that movie when i was a lil kid. 👍👍👍

Yes! Step throat is horrible… I wonder if it’s the same specific bacteria or a different one?

I played out a fantastical theory in my head years ago, although possibly during a delusional state, that perhaps the more-modern outbreaks of substance-abuse and/or mental-illness could possibly be related to & traced back to what I thought of as a "fracturing of the collective human psyche" as a direct result of the events surrounding & the emotional, generalized posttraumatic fallout of WWII.. how much of this was fact, and how much was not just another mirage.. I can't say for sure.. but I remember feeling like I was really onto something & feeling a sort of empowering, excited feeling at the prospect of dedicating my "life's work" towards proving or disproving this theory, or at the very least exploring & investigating its possibility, however I ultimately slipped deeply back into my "default" state of mind as a tortured soul, affected overwhelming by immobilizing & debilitatingly intense depression & cynicism Still, whatever the case may be, I now believe proper sleep (and possibly optimally regular sleep-wake cycles, aka circadian rhythm) as utmost importance to anyone.. especially so for those grappling with substance-abuse and/or mental-illnesses.. in my experience, when the brain begins to run low on proper R&R, the conscious mind begins to merge with & occupy the same spaces in the brain related to functions such as coordination, emotionality, cognition, impulse-control, etc. my abstract theory, at the time, was something about how mental-illness - whether *always underlying* within the human psyche, or more simply *brought on by* - had been proliferated (irrevocably & irreparably) thru the traumas that the-world-over had experienced when directly confronting the physical embodiment of soulless evil that Adolf Hitler could be considered guilty of setting into motion.. First shell-shock (WWI), then "thousand-yard stare" catatonia (WWII).. resulting in an entire generation of newly-emotionally-repressed men (who had fought) & women (who lost many of their male influences).. i.e. "baby boomers" Then, in-turn, we saw the countercultural movements & expressive renaissances which ensured in the following generation.. i.e. "flower children" (proponents of peace & compassion & empathy, protesters of the wars in Korea & Vietnam) Next, various nations involved in conflicts in the middle-east during the 80s & 90s.. finally, here, we term this mental illness "posttraumatic stress disorder" albeit under the guise of various other names dating back who knows how far.. Lastly, unable to cope with the relatively unrealistic societal expectations & demands, and having been born to parents of generally-stunted emotional intelligence & capacity, turned to drug abuse in: generation X (prevalence of MDMA & cocaine use/abuse), generation Y (introduction of crack-cocaine & more-widespread prescription of pharmaceutical-grade opiates/opioids).. finally leading us to current-date (gen Z) with hardcore heroin/fentanyl users, a supermassive explosion in drug- & mental/emotionally-related diagnoses All of this could be just my intensely-vivid imagination running wild, but at the very least would make for excellent dystopian-conspiracy sci-fi (imo, ofc)

I had PANDAS and whilst a short round of antibiotics rid my system of the strep, I still have tourette’s symptoms 13 years later. So crazy to think that it could have landed be in a sanitarium or asylum. Something like strep, scarlet fever; and other streptococcal infections could create PANDAS.

@jjchap3159 A way to speak against this is the fact that there has been horrible wars and pandemics, much more horrible than WWI and WWII, e.g. The Black Death, and The 30 Years war. Those two wars didn't change humanity in any lasting way. They just created trauma, like all wars do.

It also reminds me a bit of ME/CFS, another debilitating disease that can be caused by getting a viral infection once and then never really recovering.

Or after having had strep in childhood.

🥺

do u have it

100%. Got myocarditis and pericarditis, alongside a huge pericardial effusion from ignoring strep. I have been tired and have never been the same since. Have had constant autoimmune issues since. High WBC count, reactive thrombocytosis, high CRP, alt and ast in blood tests every time I get sick.

Agreed. I got a bad case of strep and ended up with psoriasis. Now when I’m stressed or sick, I get flare ups in random places.

Good luck getting antibiotics promptly. These days, doctors don't want to prescribe them even for bacterial infections.

@@ae2948 Interesting. In my experience, doctors are always willing to prescribe when called for, i.e. bacterial infections. I haven't experienced a fungal infection beyond athlete's foot, so I don't know about anti-fungal drugs.

@@markharder3676 The paranoia over creating "superbugs" is so prevalent that my husband and I are suffering through bacterial pneumonia right now. We could've been given antibiotics a week sooner. We weren't. He will have lung damage. Forever. All b/c they wouldn't hand over a frigging five-day course of antibiotics.... and, FYI, he has NonHodgkin Lymphoma and they STILL wouldn't give him antibiotics until he wound up in an ER needing oxygen. Took several more days for me to get mine. Yeah. It's that hard.

I saw the movie at the same time my mother was diagnosed with Early Onset Alzheimer’s disease. The similarities between the newly awakened patients and my mom’s conditions had me in tears.

@@Momcat_maggiefelinefan I am so sorry, there are such horrible illnesses/conditions out there...

Yes, he was in the forefront of brain research, as a neurologist . I read his book The Mind’s Eye, & found it informative & even entertaining. A brilliant brain scientist. Simon should make a bio video of Sachs.

In a way it kind of sounds like an extreme case of long covid like Physicsgirl has.

Me too except the covid bit. Hope you feel better.

After I had covid the first time I developed an autoimmune disorder and symptoms from my personality disorders have also worsened greatly. And same, I can easily sleep for 18 hours at a time, and honestly a lot of the time its 24-62 hours at a time. Its fucking awfullll. Also I feel you on the multiple Rona thing, I've had it 3 times and its basically rendered me periodically disabled for multiple weeks at a time. Ffff this

Yup: I’ve got CFS, fibromyalgia and am on the ASD spectrum (among other things). Had Covid once, so far, despite being a hermit. Circadian rhythms are a joke at this point. I hate that this happens to anyone.

How do you… live?

THATS HORRIFIC

Channels just not big enough for them yet. Simon's an outright capitalist and once the sponsors take note of this channel they'll be on here as well. It's how he and the other production staff make a living so I'm not mad

@@CTP909 sadly you were right. I figured that because he’s got a million channels, the sponsor sharks would be all over the channel straight away. I mean, capitalism is not *always* an evil thing, but it would be nice to see some historically significant tragedies and whatnot be given the respect and solidarity they deserve, not have some stupid sponsorship getting in the way. Some of this education and material is not only priceless but timeless, and may well be shown in an educational setting decades from now. Sponsorships somewhat kneecapping this aside-I know a man’s gotta eat-but if it were my production, I sure as hell wouldn’t feel right having a Hello Fresh ad with a relatively manic attitude with upbeat music and fake smiling and glee slapped right in the middle of a documentary piece about the Holodomor, but maybe that’s just me.

I had issues with fatigue due to a medication in the past where I’d sleep for 16+ hours a day only to be absolutely exhausted while I was awake. I’m so lucky that I just had to change meds and it went away, I couldn’t imagine having to go through that for the rest of my life. I hope that things go well for you.

I have narcolepsy and being chronically tired changes you as a person. Completely changes your outlook on life and your personality.

If the human brain was simple enough to understand we'd be to simple to understand it

Multiple Sclerosis? I thought it was an autoimmune disorder.

@@partlycloudy7707 Indeed it is autoimmune. But we don't know what really causes auto immune disorders- some think it is random, others attribute it to post infection response.

@@jackwilson5542 one part that could cause some auto immune disorders is how the body makes immune cells. (Specifically killer B and T cells). I'm going to use some language from kurzgesagt (go watch them) in this brief description. Everything at the cellular level is all about proteins and how they fit together, including identifying friend or foe. Our bodies are immune to everything that ever has or ever will exist because our specialist cells are very potent, but to be speciallized for everything you can't store the recipes in your DNA. So in the Thymus we hold "murder university" where new immune cells are made and given permission to do some DNA shuffling to make new protein receptors to identify enemies with, but they could randomly generate ones that target you instead or aswell. So in murder university they are presented a sampling of every protein in the body and if they react the "teachers" order it to sepuku itself and explode, only 2% of a class graduates Murder U. A theory is that if a cell escapes the Thymus (Murder U) and has a recipe for for your own proteins (98% chance) then it causes an autoimmune disease as it has free reign of the body. (Healthy immune cells might not recognize it, and they normally to a good job snuffing out cancer before it grows to a problematic state) The Kurzgesagt video I'm referancing is titled something along the lines of "How you are immune to every disease ever" and I encourage watching it. Their are probably many other pathways for autoimmune problems see as the brain and immune system are 2 of the most complex parts of the human body. Off the top of my head neutrophils are generalist immune response cells that are very hyper killing obsessed and will overreact to 1 bad cell forcing your macrophages to hide the 1 cancer cell they killed before the neutrophil kills 100 more healthy cells, so i wouldn't put it past them to mess up during a particularly strong immune response. (Also Covid infects and stimulates the immune system causing all those blood clots by triggering defenses not intended for viruses)

Lots of interesting research happening now with MS and super high Vit D dosing and a super high success rate compared to the big pharma super drugs. Other interesting research indicates excessive exposure to environmental chemicals and simultaneous high levels of systemic inflammation (caused by oxidation in modern diets) causes the immune system to go a little crazy with all this damage control it shouldn’t be doing and it just starts attacking all kinds of things it shouldn’t thus the diagnosis of ‘Multiple’ Sclerosis

I was a lot of chanels that normally don't include the typical "begging" for like and subscribe (sometimes they will try it and notice a sudden surge in subscribers and hate that it works), but even then they normally have some sort of goodbye or outro (as simple as saying by or see you next episode or something). So I don't notice its absence and more often get annoyed by the presence of any super noticable cheesy "smash that like button and subscribe for more" bits.

sounds like a neurological disease, im so sorry about that. i have MS and though its not of the progressive kind going numb, cold and unable to walk without knowing what was going on for several weeks was very scary and a motive to freak out, but my gp dismissed it the first time it happened. im glad you got an appointment with the neurologist, better late than never

I'm a serial stroke patient that started in my 30s. No one took that first one seriously until I went through evry neurologist in the academic hospital I worked at. Finally the neurologist who saw senior stroke patients saw me, ruled everything out, but said yes you did stroke we don't know why. It wasn't until genetic testing advanced over the years, that it was found I have a connective tissue disorder that affects blood vessels. Then 24yrs after stroke 1, I finally got blood thinners and other drugs. I stopped having the strokes every 2 yrs. Since CT scans showed damage back at stroke 1, why didn't anyone start me on blood thinners etc then. So anyone that is a Zebra, gets ignored because most MDs treat horses. Now no neurologist will follow me because I'm a known stroke survivor, and they don't "do" the disorder. So no one monitors my stroke risk anymore. I empathize with the sleeping sickness sufferers, and others I comments struggling with M.E. and other Zebra disorders.

@@joywebster2678 I'm sorry you have to go through that... It's a sad situation...

Also it is correct. I have Hydrocephalus, and naturally there are arguments whether the C is hard (as in Greek, the root language) or soft as Americans often pronounce it.

I came to the comments just to see if someone commented on this! Damn Brits need to learn how to speak English properly 😜

“I thought this country spawned the fucking language, and so far nobody seems to speak it.”

@@kathryncumberland Funny, we say the same about damned Yanks! 😄

Neil Gaiman's? I absolutely loved the graphic novels when I read them.

@@-xirx- yeah exactly. The audio books are pretty great too, a ton of awesome voice actors

@@CCCW wow, cheers! I'll have to check them out.

I first read Preludes and Nocturnes many years ago, and I was horrified to later find out this is a real disease which can still affect people. I have some neurological problems, fortunately it's not terminal, but brain disorders are IMO some of the scariest conditions you can get. Love Neil Gaiman though.

I currently have a sore throat (covid's a bitch) and hearing him say these started with that made me shit myself.

@@haveagoodday7021 So...now it's coming out of both ends? Yowsers I hadn't seen a friend in a while, and when he showed up in our little group I asked him where he'd been. He told me he was diagnosed with Crohn's Disease, a sickness of the bowels. He said before he was diagnosed he was on the toilet for a week. I said, "Well, at least you caught up on your reading." I didn't realize someone heard me until they turned around with a big ol' grin on their face. Truth truly is stranger than fiction...Thank you, and I hope nobody's rude to you

My dad became a research neurologist. Now I wonder when he was a kid, if he was inspired by this disease.......🤔

My friend had scarlet fever in the 1960s.

I am intrigued!

Ughh please explain

WTF ?

You have my attention. It would be nice if Simon told this story.

That's where the show justified takes place but it has nothing to do with that. Still a great show.

I think i was a bit confused as i read alot about this kind of subject.Anne boelyn and Cardinal woolsey bothe had and recovered from it.

April, the disease that affected your cousin was probably a different kind of encephalitis than the one in the video. It was likely Eastern Equine Encephalitis, a viral disease of horses that is passed to humans through mosquito bites. When I was in elementary school in the 60s, a classmate’s younger brother died of it. It’s particularly dangerous to young children. It’s very rare, but it’s still around.

I'm glad she survived but believing prayer saved you (her) while it didn't save others is such a disgustingly selfish position to hold. There's the "well God loves me more than the next person so MY prayers got answered" angle and then there is of course "if it's not working for you it's because you're not doing it right / not praying hard enough / not doing it with an open enough heart" etc angle, both of which are deplorable

I was also thinking this

Prion disease is 100% fatal, from what I've read.

and I also have tics ! yay :c

Me, with a sore throat: oh so this is how I die.

Haha yeah I've got that day night sleep reversal thing.

This does happen with both bacteria and viruses. It could be one cause of the decline of the illness.

Strep is a bacteria which is why we can treat it with antibiotics, so if its caused (even partially) by a bacterium then our modern use (and overuse) of antibiotics when we identify a bacterial caused "cold" its possible that it gets accidentally cured as an unidentified bacterial infection. And we are slowly working on a general antiviral. We have tamaflu as an antiviral medication specific for the flu that has some highly specific requirements to work. (Mainly to take it before your symptomatic)

we may be luckily alive on this world due to a plague inc newbie....

Strep is a bacteria, for one, and for another, we only had 14 countries that were legally required to report cases of this disease. So its true scope is unknown. It also wasn't *that* noticeable by 1920s standards. With active smallpox, leprosy, etc etc around the globe someone showing up with fever and neurological symptoms could've been classed as anything from "brain fever" (marvelously vague term) to rabies to Parkinsons. Not many everyday docs had the ability to tell the difference back then. (Or now, to be fair.) Brain lesions indicate no abatement of infection/reaction, so it's possible this is a substrain of strep that simply hit some people quite hard and didn't do so to others ----- a common epidemiological pattern. There are many factors to consider, such as blood antigen factors (ie ABO), epigenetic issues from exposure to toxins pre-infection, and so on. We'll probably never know for sure. And I'm okay with that, b/c we'd need another epidemic to get the data.

Maybe the legend of Rip Van Winkle as well?

Cool! That's like giving stimulants to ADD and ADHD patients counterintuitively helping them focus and somehow micro doses of certain poisons also counterintuitively being more dangerous than a slightly larger dose (though I forget where I saw that)

Yes we know

If you mean his pronunciation as "enKefalitis", that's a recognized alternative pronunciation common in Britain. It's also technically more true to the original Greek: κεφάλι (kefali) = head

There was a wave of it in the 17th century? I was thinking one of the forms of sleeping sickness, the form with the muscle movements, could be the explanation for the dancing plagues that hit during the Middle Ages and continued into the 17th century. No one has figured out what caused it. I thought it was Tourette’s but it would require large numbers of people with Tourette’s living in a community to be the explanation. Honestly this disease, the sweating sickness (which I think could have originated within the Hanseatic League as one of the items traded by the league were furs) and the dancing plague are among the most mysterious, still unexplained, illnesses

I have read this context in a book called Great Disasters a book if i recall was a time life publication.So many different epidemics were in it i lost count.Syphilis was one that was excluded for some strange reason.

The first outbreak was in 1485.It was more prevelent in men less common in women and seemed to be more in those in the military and royal families.Most peasents did not seem to get it.Anne Boleyn contracted it in 1528 i believe it said in the book.It also skipped generations and reappeared and became worse with each reaccurence.Cardinal woolsey also contracted the disease and recovered.