You are living encyclopaedia.. great job sir... best teacher with good content and excellent teaching skill😊

I use your lectures for literally every subject of my education. Thank you so much! Greetings from the Netherlands

Really u r a library sir....thank u sir thank u soo much its helping me more than online classes.

From my high school times to my present Masters days, you are the longest-running teacher of mine. Thanks for everything Somu!

brilliantly explained! P.S. RISC stands for RNA induced silencing complex.

I am a pharmacy postgraduate working in a biotech company. Your lectures are a great help to me for learning the biotechnology basics. Thank you

Such a clear explanation!!! I use your lectures as a guide for my Master's prog in the USA. So grateful to you. Great job!!!

I am an MBBS student and ur videos are amazing .No words to admire your teaching style.Keep it up sir.

THANK YOU! This is the best explanation I have seen so far. You should be a professor at IISc or something!

Love you Brother from Afghanistan 🇦🇫 That was an Informative Video about RNAi and its Types. Thank you so much for your help.

You really good in explain it all even no matter how hard to understand it

good job. i have a strong feeling that ur teaching style is inspired by Dr. Najeeb...

this video is extremely helpful. thank you would you consider doing one with miRNA and its affect on cancer?

Thanks, very helpful. What can you suggest for my review, be taking comprehensive exam for my PhD soon. Thanks.

Thank u very much,you help me whit this video very very much because I had seminar about miRNA at university …🙏🙏

Nice video NB: You are saying 3' overhang while you are drawing a 5' overhang !

Though there were some mistakes like in full form of RISC and regarding the overhanging sites. But I loved your way of teaching, you cleared my doubts. You are a good teacher 👏👍

indeed good explained really clear and easy to comprehend, but at beginning you said slicer protein has RNase H, and somewhere to the end when explaining miRNA-mRNA duplex, you said argonout has RNase H activity? :/

Thank you sir. I really love watching your videos , it gives us so much of knowledge. You are awesome.

Thank-you so much Sir for this easy-to-understand explanation, I'm sure I can remember this for longer period of time. Again Thank-you for your Time and Support.

Wow, what a great learning experience of miRNA mechanism...with you Sir...Thanks a lot

This video is very helpful and now i understood actual gene silencing mechanism. Thank u very much sir and u have good explanation skill.

its awesome sir......ur all videos are very well explained & help me so much...

Sir, u made it easy . Thank u , and keep making more lectures . Specially these lectures are more helpful in present covid situation because we are not attending the offline classes of my institutions.

Great job. Just one correction the overhang is at 3' but shown at 5'. I am sure you may have already realized that 😊

had to describe the whole process at the exam.thanks for the help

I don't know why I pay for college honestly. God bless you!

Your knowledge in diversity is administerable

These videos cleared all my dought thanks sir

Great teacher god bless you

Thank you very much you help me so much

It is really perfect explanation. I am really so glad to watch it. thank you

This is really helpful. I bet this is the most easy, well-explained video on youtube about miRNA :D Since I'm not really good at English, would someone explain why the last progress is important?

This video was soo helpful Sir.

Totally clear and informative, great job!

Very very helpful video .Thank u sir

Thanku so much gurujii.....u helped me a lott.....i was nt able to understand the mechanism of rna from book it is totally exausting 4 me but when i found ur video nd after watching ur lecture i understand all d things ......thanku so much sir..🙏

Good video. Thank you.

Sir, it is a humble request to explain identification (bioinformatics tools) of micro RNAs (miRNAs) and mRNA targets. Thank you in anticipation

salute!!!! explained brilliantly in simplified way...

Very much cleared after watching ur vdo

He is very very outstanding lecturee, may Allah Pak blessed you☺️

So precisely described 👌

The way you explain is simply impeccable.. Thanks a lot! 😊

Wonderful lecture! Thank you!

This lecturer is really very helpful for me...thank u so much sir...😊👌👌👌

Nice... well explained sir

thank you for explaining it so clearly

you are a great teacher🥺

Is there any recognition mechanism for RNase H to cleave only targeted RNA not mi RNA?

Sir is there any experiment related to Molecular mechanisms that may cause drug resistance to increase microRNA-21 levels in ovarian cancer

very helpful video it is..... Thank you sir......

Very nice sir 👍

awsome video.................love to watch it again n again

This is so beautiful, Thank you Shomu sir

thank you sir.. it was very helpfull

Awsome.. U have explained it very well

Amazing sir

at 10:24 you state its 3' overhang but you've drawn 5' overhang.

Well Explained

simply wow ❤❤

very helpful.......thanks a lot

very helpful... thanks...

Thank you sir. I very much helpful from this vedio.

Great Job

Thank you so much sir 😊❤

I feel good after watching this, do you have video about transcription explaining why lagging and leading strand ?

amazing lecturer

Excellent 🔥

Thank you for the brilliant explanation! Your didactics to teach is great! I have a doubt, and would appreciate if you can help me (I need to solve for my internal PhD defense): are we producing miRNA all the time, or do we need a stimuli to produce it? More specifically talking, are there some kind of food which could make us to produce it? For example, could be that a high adherence to a healthy diet and its phytochemical could "silence inflammatory genes" through the production of some specific miRNAs, which interfere with mRNA of genes related to inflammation (e.g. CRP)? So, in case there is this interference, the mRNA of CRP will not be translated, and so the concentration of CRP in blood will be decreased by this mechanism. Is it correct?

Very good

great lecture, thank you so much

You are awesome sir. All of your videos help me so much in my genetics class I wish I had you as the professor

thank you so much for this video it was really helpful for me to understand what is exactly Micro-RNA and how it is produced

Amazing

Full form of RISC is RNA Induced Silencing Complex

Dear Suman sir, in ur previous video (basics of RNAi) u said that argonout is a type of RNase III type but sir, here u r saying it is a type of RNase h type. Which one is correct sir?

Thank you, this is really helpfull! keep going

very helpful

Thank you for your effort

Very good explanation sir. You make rna easy to understand 😊.

Very good explanation really

thank you , it was very helpfull

Very nice explanations

Sir in the 3 prime overhang of mi rna why the two nucleotide are present in the 5' end it should be present in 3 prime side .

Thank you

What is the work of passenger strand

thx a lot, that is really helpful.

Nice presentation

Thts grt

first of all, commendable job by you.. kuddos to your teaching ability. But there is a misinfromation in your first indroductory video where u said Argonaute is a RNase III type which was wrong as it is RNase H type.

*_clean_*

THANK YOU SO MUCH

Hello sir, is this 5' overhang or 3' overhang???

Tq sir.

sir can you please, share the reference textbook you used ,for this topic?

Dude thanks for the help. Exam is monday

awesome video.. thanks a lot BT it seems u change the function of piwi n paz domain... if possible plz reply

what is the significance of stem loop ?

Hi, can I ask is there any way the target mrna can prevent the miRNA from binding to it to protect itself from degradation?