miRNA | micro RNA mechanism of gene silencing

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miRNA | micro RNA mechanism of gene silencing

Рет қаралды 55,385

Күн бұрын

miRNA | micro RNA mechanism of gene silencing - This lecture explains about the details mechanism of miRNA gene silencing. The process of micro rna or miRNA mediated gene silencing will be clearly explained with the help of this video lecture. Microrma is a type of rna interference or RNAi type of small double stranded rna with endogenous origin inside the cell and it cleaves target rna before the translation process. Stay tuned to this video to learn the following -
What is Microrna?
How micro rna produced?
How micro rma works?
Microrna mechanism
MiRNA mediated gene silencing mechanism
Principle of miRNA mediated gene silencing.
This lecture will be helpful for CSIR net, Gate, icmr jrf, ICAR net, bet, JNU, ncbs, IISER PhD entrance exams.
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Thank you for watching the video lecture on microrna mediated gene silencing also known as the miRNA mediated gene silencing in cell. This lecture will be helpful for CSIR net, Gate, icmr jrf, ICAR net, bet, JNU, ncbs, IISER PhD entrance exams.

Пікірлер: 107

@GauravGhatak 3 жыл бұрын

I have been studying from your videos since my first year. I am in my last sem of my masters preparing for csir. And your videos are still getting better day by day. Keep growing and helping students ❤️

@shomusbiologyofficial 3 жыл бұрын

Thank you so much for appreciating my efforts

@Ajcutzz 8 ай бұрын

tmw I will pass in Xam bcoz of this one man

@shomusbiologyofficial 8 ай бұрын

All the best

@hanaa1301 3 жыл бұрын

I liked it more when you used the white board. Thanks for your help as always!

@shomusbiologyofficial 3 жыл бұрын

Thank you

@robindurand9384 3 жыл бұрын

That's just the right timing! Thank you for the recap.

@parijatdas2822 3 жыл бұрын

Dada.. Thank you so much for everything..I'm going to work as Microbiologist in "COVID19 Testing Center" at Wales, United Kingdom from next week..tar Aage tomar SARS CoV-2 er Videos gulo ar ekbar revise korlam..it's really helpful as always.. Thanks once again..jotobar thanks bolbo it won't be enough..

@shomusbiologyofficial 3 жыл бұрын

That's good opportunity. All the very best

@parijatdas2822 3 жыл бұрын

@@shomusbiologyofficial Thank you Dada 🙏

@VishalSirBotany 3 жыл бұрын

Thank you sir...😊 From today I will be your regular student....

@shomusbiologyofficial 3 жыл бұрын

Glad to hear that you're getting benefit from my lectures. Please subscribe and share

@rekhasah1760 3 жыл бұрын

Your lecture is very helpful. Keep shining 🙂

@bunny8352 3 жыл бұрын

Please I Pray that you live a very long life the world's doctors need you

@sudipabhattacharya107 3 жыл бұрын

just have been going through this topic sir ..valolaglo as usual 🙏

@shomusbiologyofficial 3 жыл бұрын

You're welcome. Glad to hear that you're getting benefit from my lectures

@zareefatima6794 2 жыл бұрын

too good bro too good...❤❤

@shomusbiologyofficial 2 жыл бұрын

Thank you so much for appreciating my efforts

@nishattasnim9549 2 жыл бұрын

I pay college but learn from you. Thank you so much sir ☆

@shomusbiologyofficial 2 жыл бұрын

Thank you so much for appreciating my efforts

@leilaaghaiyan6037 3 жыл бұрын

you are the best in biology and I use your videos as references which can't find anywhere. I liked it more when you used the whiteboard.

@shomusbiologyofficial 3 жыл бұрын

Thank you so much for appreciating my efforts

@bhaskarsharma9002 Жыл бұрын

Very nice explanation and very very helpful video, thank you so much sir ❤🎉

@shomusbiologyofficial Жыл бұрын

You're welcome

@gemaradisulasandyno9777 3 жыл бұрын

sir you is my best teachers,, big thankyou for your conetnt

@gemaradisulasandyno9777 3 жыл бұрын

are*

@crystal-ur3tf 2 жыл бұрын

Outstanding vdo sir....easy to understand

@shomusbiologyofficial 2 жыл бұрын

Thank you so much for appreciating my efforts

@reshmygs5081 3 жыл бұрын

Can you explain the role of miRNA in obesity.Also which are the clinical potential miRNA in obesity

@asuramunikavishadesilva371 8 ай бұрын

Thank you! 🙏❤

@shomusbiologyofficial 8 ай бұрын

You're welcome

@letslearntogether.4336 3 жыл бұрын

3rd comment.... Sir i just want to say you a "Big Thankyouu for every lecture"💞💞💞

@shomusbiologyofficial 3 жыл бұрын

Thank you so much for appreciating my efforts

@_vandana_BT_ 3 жыл бұрын

Thank you sir for recalling the concept 😊

@shomusbiologyofficial 3 жыл бұрын

Thank you

@arpanchakrabarty2464 3 жыл бұрын

Presentation ta darunnn...thank you so much dada...😊😊

@shomusbiologyofficial 3 жыл бұрын

You're welcome. Glad to hear that you're getting benefit from my lectures

@kiehore9961 3 жыл бұрын

Hi bro , please make video on mutation of SCA disease ,and what we need to do repairs the mutation Thank you

@hemanthm.n645 2 жыл бұрын

Great work sir

@shomusbiologyofficial 2 жыл бұрын

Thank you

@rapallysunayana3229 3 жыл бұрын

Thank you very much for your lectures.. and also please do video on MRSA & anotamy and physiology videos..

@shomusbiologyofficial 3 жыл бұрын

Okay. Thank you

@manahilakram229 2 жыл бұрын

Plzzzz use white board....thats the best way of getting concepts and i m used to with it also plzzz don't change the format

@shomusbiologyofficial 2 жыл бұрын

Thank you

@KhushiGupta-tx6jl 3 жыл бұрын

Can u provide a vdo regarding microbiology..as i think I've interested in this only plz provide a short knowledge via vdo obviously that what is microbiology nd what is all about,?

@Tariq5P 3 жыл бұрын

A huge respect from Pakistan Sir... Sir I have heard that the AGO2 protein is not activated in miRNA case that's why it's target mRNA either repress by translation fectors or degrade by exonuclease enzymes. The cleavage will only possible when 100% complementary occur between the miRNA to it's target mRNA which is very rare. I could be wrong.

@shomusbiologyofficial 3 жыл бұрын

Thank you

@nehachaudhary239 3 жыл бұрын

Thank u sir❤

@shomusbiologyofficial 3 жыл бұрын

You're welcome. Glad to hear that you're getting benefit from my lectures

@fallseason5163 2 жыл бұрын

Perfect 👍🏻 thanks

@shomusbiologyofficial 2 жыл бұрын

You're welcome

@sobiimran2508 3 жыл бұрын

Kindly sir make a vedio on RNA silencing by siRNAs

@shomusbiologyofficial 3 жыл бұрын

Sure. Next video

@subhashreepothal7100 3 жыл бұрын

Thanks sir😊👍

@shomusbiologyofficial 3 жыл бұрын

You're welcome

@n0yn0y 3 жыл бұрын

Me: An American student looking for biology instructional videos on KZfaq because my professor doesn't clearly explain the concepts. Random Indian fellow on youtube: "It's free real estate"

@hanmantbhosale1646 3 жыл бұрын

Sir I requested you make a video about cardiovascular disease and drugs

@hanmantbhosale1646 3 жыл бұрын

Please sir

@SailajaSadineniNS 3 жыл бұрын

Sir please board use karo is se toda teacher wala feel araha hai, you are doing great as professor on board.

@shomusbiologyofficial 3 жыл бұрын

Thank you

@kirtipatel8848 3 жыл бұрын

Thank you so much sir 🙏🙏🙏

@shomusbiologyofficial 3 жыл бұрын

You're welcome. Glad to hear that you're getting benefit from my lectures

@aysharizwana2370 3 жыл бұрын

Thank you sir....u saved me ...😅

@shomusbiologyofficial 3 жыл бұрын

You're welcome. Glad to hear that you're getting benefit from my lectures

@vishalbhargava2735 8 ай бұрын

Please make the videos are in Hindi version too. Causing I'm unable to understand properly as well not clear the concept or those who are not good in English.

@shomusbiologyofficial 8 ай бұрын

There are plenty hindi channels. I keep mine to English only

@quinattasneemrafique536 3 жыл бұрын

Happy Teachers Day, Sir.🥰

@shomusbiologyofficial 3 жыл бұрын

Thank you

@davidkincade7161 3 жыл бұрын

The mechanisms are all very nice- but just remember this all means the CELLS are doing this... they invented this process and carry it out- pretty smart isn’t it!!

@shomusbiologyofficial 3 жыл бұрын

Yes. Its exciting

@borgshadow13 3 жыл бұрын

me: german dude starting a PhD involving miRNA and having no clue whatsoever. MVP Shuman: "finger guns" - you need a recap ? let me explain ! as a little piece of constructive feedback: a clarification you are talking about processes within animals would be bueno :)

@PoKeDoN1992 2 жыл бұрын

How do you Inhibit the expression of mir-16 and mir-135a in the dorsal raphe? Both of these mrna's are increased by ssri's which suppresses sert and causes pssd.

@sobiimran2508 3 жыл бұрын

Thnxs it's good

@shomusbiologyofficial 3 жыл бұрын

You're welcome. Glad to hear that you're getting benefit from my lectures

@chuggie-6977 Жыл бұрын

Banger

@senthilkumar-eo3ym 3 жыл бұрын

Dear sir we are waiting for your video about CSIR cutoff prediction for June 2020?..hope you release soon..

@guenryukeats5157 3 жыл бұрын

May you please say what are mirtrons? Are they a part of the RISC or they can only become a part of the RISC only after being converted to miRNA?

@KamyaChavan22 Жыл бұрын

hey how mirna is used as tumor suppressor gene?

@salemsulimanbaldi285 3 жыл бұрын

Do all supressor genes have the same function of p53 to activate pri-miRNA and thus produce specific miRNA that ultimatley degrate target mRNA?

@angrybird1432 3 жыл бұрын

Tq sir 🙏

@shomusbiologyofficial 3 жыл бұрын

You're welcome

@akshaybvyawahare3363 3 жыл бұрын

Sir pls make a video on how to design primers for the miRNAs

@shomusbiologyofficial 3 жыл бұрын

Sure

@nizarberrim9723 3 жыл бұрын

what did you mean by high arn?

@SauravKumar-yn7qq 3 жыл бұрын

bro what is diff between human rna and covid rna??? is there any way to remove virus Rna when ot released inside cell??

@sailajakambhampati9071 3 жыл бұрын

Hello Sir can you make a video about Modeller software & how to run a sequence lThank you

@shomusbiologyofficial 3 жыл бұрын

Later

@akshinbarathi8914 3 жыл бұрын

WHY IS IT ONLY 19 TO 24 BP DOESNT THE miRNA SIZE DEPEND ON THE GENETIC MATERIAL LENGHT THAT IT IS SILENCING?

@krinapatel7498 3 жыл бұрын

In end of video you are saying siRNA instead of miRNA. Is it by mistake or by siRNA you r indicating same as miRNA???

@shomusbiologyofficial 3 жыл бұрын

Need to check. Can be slip of tongue

@krinapatel7498 3 жыл бұрын

@@shomusbiologyofficial ok sir, btw video is very informative and in detail. Thank you so much sir for solving my confusion☺.

@rabindrakhatiwada3558 3 жыл бұрын

different mode of gene silencing by mi rna mean

@dipakpaul9501 3 жыл бұрын

sir can u pls make a video on carbon sequestration..

@shomusbiologyofficial 3 жыл бұрын

Okay later

@dipakpaul9501 3 жыл бұрын

thanks sir..

@anupbhatavadekar1831 3 жыл бұрын

Hello sir I'm Anup studing Bsc in Bangalore , just now I watched your video on mechanism of miRNA in that you said that the PIWI domain of Argonaut has catalytic motifs that actually cleaves the phosphodiester linkage But i watched another animated video for simple visualisation in that they said that 5' end which is attached at PIWI domain is not perfectly positioned and cannot cleave mRNA ... instead they said a protein called TRNC 6 containing glycine tryptophan repeats repress translation and cleave mRNASo could please clarify my doubt mentioned above .... I'm getting bit confused that who actually cleaves the mRNA

@SakshamMaria_ 3 жыл бұрын

Ist view is mine ✌️

@shomusbiologyofficial 3 жыл бұрын

Thank you

@drshahparin 3 жыл бұрын

👍🏻

@shomusbiologyofficial 3 жыл бұрын

Thank you

@amitgangwar3008 3 жыл бұрын

Sir please start neet crash course

@shomusbiologyofficial 3 жыл бұрын

I don't like crash course idea

@amitgangwar3008 3 жыл бұрын

I mean to say that u are already uploaded human reproduction for neet so plz keep uploading next chapter according to syllabus...many neet aspirant are follow your lecture