Targeting Disease - Drug Discovery & Virus Targeting

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SBA School of Science and Engineering at LUMS

SBA School of Science and Engineering at LUMS

3 жыл бұрын

In the great melodrama of life on Earth, diseases have played the role of an effective antagonist. Researchers at SBASSE are busy with developing new ways to fight disease through the fusion of cutting-edge technology, drug discovery and vaccine development. The work highlighted in this video is led by Dr. Rahman Shah Zaib Saleem and Dr. Shahzad ul Hussan.
Treatment of cancer, a disease that is one of the leading contributors to mortality, is often complicated by development of the multidrug resistance in the patient. The Drug Discovery Labs at SBASSE aims to develop drugs of the future that can target specific cellular pathways critical for the development and progression of cancer and at the same time help overcome multidrug resistance.
Focus of Biochemistry and Structural Biology Research Group, led by Dr. Shahzad ul Hussan is to discover potential antiviral drugs, create knowledge that can guide to develop successful vaccines and understand the details of viral infections at atomic-level to help in devising better strategies to combat viral infections. For achieving these goals, research teams at SBASSE are working on four different globally and locally prevalent viruses including HIV, Hepatitis C virus (HCV), dengue virus and SARS-CoV-2.

Пікірлер: 3
@ziatoor4181
@ziatoor4181 2 жыл бұрын
Hello Sir, here are a couple of proposals for your researchers. 1. injection of ionic iodinated contrast agent IOHEXOL for delivery of antiseptic-iodine systemically. 2. adding standard (2%) LUGOL's iodine to a standard Normal Saline so that the total Potassium Ion does not exceed 4 mmol/L and results in around 300ppm - parts per million (microgram/ml) in sterile solution and delivered as a controlled infusion to a critical patient. 3. nebulizing the solution in (2) with oxygen to a patient with high oxygen requirement in the hope of delivering anti-septic iodide ion to the lung and hopefully neutralizing the deeply embedded viral colonies. 4. Iodinating a portion of low molecular weight hydroxyethylstarch solution (used as a plasma volume expander) and delivering as an infusion whereas the starch component carries the antiviral penta-iodide ion. Best wishes and regards. zia hameed toor/sialkot.
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