As a biochemist I have to say that I loved the comparison to Napoleon and the whole explanation example. I am gonna remember this if I ever again have to explain immune response to someone who is not so into sciences.

Using Napoleon's face to explain antigens was brilliant

So, only one kind of universal antivaxers?

It's why we can't treat every kind of cancer, because each one is different. That each person is effected differently even when the same type of cancer is present.

I have honestly never seen such a good impression of Napoleon Bonaparte in my entire life, and I don't think I ever will again. So amazing

Just waiting for all the unbiased, reasonable discussion that is bound to happen in the comments on this topic

This is hilarious and informative, explains complex concepts in simple ways to people without professional backgrounds. Hats off to the wonderful scriptwriters and animators! I wonder who came up with the idea of comparing the shape of hemagglutinin to Napoleon's bust, ahahaha!

As a biology student and someone who wants to become a scientist(oncologist) such videos multiply my interest and curiosity a solid 50 times!!!❤️ Thank you TedEd

This video finally made me understand why flu's passed on from animals are such a big deal. I already knew that they're dangerous and highly infectious, but I never understood WHY that's how it is. And now I know. From a video that's not even 6 minutes. I love this.

The TED-Ed intro music is always a big comfort knowing you're about to be given new knowledge by incredible animations:)

This was more optimistic than I expected

"think of hemagglutinin as a bust of 19th century french emperor napoleon bonaparte" is one of my favorite strings of words of all time. thank you ted ed

That's fascinating to see that we can retrain the body to recognize things it's never used before! It'll be really interesting to see what they can come up with in the coming years!

Honestly, I’m in 4th grade and I’m not supposed to learn this stuff until like 10th grade, but I guess at least I know what antibodies mean!

I have noticed a confusing detail in the apparent size of ferritin. At 0:10 you say it is 10^-10 meters (Wiki (en.wikipedia.org/wiki/Ferritin) says the same and I can't make heads or tales of the source), or 100 picometers (pm= 10^-12 meter). There are atoms bigger than that ("Diameter range 62 pm (He) to 520 pm (Cs)" en.wikipedia.org/wiki/Atom). How could a complex protein, to say nothing of an organic molecule, possibly be so small?

Just using Napoleon as an example was funny enough, when he said *_c r o i s s a n t_* I laughed so hard that I almost couldn't breathe

Your videos are very informative and easy to understand ❤️

I did not chose medical science so i cannot directly contribute, But one day ill become rich enough to support the people who make my and other peoples lives better

Achievement Unlocked: How Did We Get Here?

The presentation is well-done, I dare say.

When you hear that original ted-ed intro music you know you're about to learn a fact plus new knowledge

very informative great video. should be shown in all schools

Ten billionths of a meter is 10**-8, not 10**-10, which would be about the size of a single atom.

Can anyone please share the link to ferritin based hemagluttinin vaccine study?

This is how most zombie movie start

Hey ted ed, i am very fond your videos and some explanations do really fascinate me, although I find your way of explaining mysterious things a bit of challenging as you use chemical reactions amd stuff that I am not very good at, as a suggestion I would ask for a more up to the point meaning for explanations and actual working of all your videos. Thank you

Super pedagogical!

Irrelevant but this animation style put a smile on my face 😂😂

🤣🤣 I only came here for the *COMMENT SECTION...* But this turned into an AMAZING presentation ❤❤

I love you, Ted-Ed

Thank you!

The Napolean faced antibodies are so creepy 😭

If its a bullet and dispensed by a gun then it sure can!

Can you do a video on immune privilege?

How much storage do your memory cells have? Maybe we can expand it via same form of memory card-like implant?

In the future, could you do a video about (hypothetical) time-travel?

The "croissant" catched me off guard

Yes! Please do. I've been hospitalized several times with Pneumonia. I hate the flu.

Animation here is a masterpiece 🎉

Wait until chopper make it okey, i don't know when, just be patient

I wonder what the side effects of such a vaccine would be?

Or we could genetically modify ourselves to be so different that no viruses could infect us.

this sounds like some 1880 snakeoil c0caine cough syrup ad 🤣🤣

In the TED-ED talk “Could One Vaccine Protect Against Everything?” The idea of developing a universal vaccine that could protect against a wide range of diseases is explored. The mechanism by which traditional vaccines work is broken down into bey simple and easy to understand words and graphics. It is explained that traditional vaccines work by exposing the immune system to a weakened or dead version of a specific virus or bacteria allowing the self-immune system to recognize this pathogen and fight it off while creating a self-defense and memory against future infections. The video then brings up the important discussion point that developing vaccines for every single infectious disease can be lengthy and costly. The idea is then posed that instead of creating individual vaccines, we could instead develop a single vaccine that targets a fundamental aspect of the immune system, allowing it to better recognize and fight off a wider range of pathogens. It is noted in the video that a variety of approaches encompassing this idea are currently being worked on by researchers. This video addresses and poses a resolution for the ethical principle of beneficence. The development of a universal vaccine has the potential to significantly benefit individuals and communities by protecting them against a wide range of diseases with one single shot. However, the principle of beneficence must be balanced with other ethical principles kept in mind. One potential ethical concern that came to mind from watching this video is the issue of equal distribution. Isn’t it likely that is a universal vaccine were to become available that it would be expensive and access would be limited? Could this idea potentially exacerbate existing health inequalities and result in some in some individuals and populations not having access to such protection as discussed in an article by Habib et al.? Furthermore, I also feel it is possible that with the invention of a universal vaccine, that other medical interventions such as hand washing, practicing good hygiene, and avoiding contact with sick individuals may become overlooked or have less emphasis on teaching them. This could lead to a possible decrease in funding and resources for other important public health measures, and ultimately have negative consequences in the long run. I would love to hear others thoughts on how we can balance the principle of beneficence with other ethical principles such as non-maleficence when it comes to the development of a universal vaccine. How can we ensure that the benefits from a universal vaccine are distributed fairly and do not lead to unintended harm? Please feel free to share and insight you may have on this topic.

My favorite video 👍👍thanks for sharing my friend 🙏😇🙏

*Happiness and sorrow vanish when one falls asleep*

Remind me, how did that Vid jab work out? No adverse effects and deaths? Not allowed to talk about those adverse effects of course...

If the title is a question, the answer is almost certainly “no”. Betteridge’s law of headlines.

It can never happen disease Is a regulator in human population if this would happen their would be a population boom, all diseases (except the ones that can cause extiction or under population) are good

an unbelievable question...some kinds of bacteria have differences types like streptococcus pneumoniae,a vaccine can only protects some of them but not all.

yes! and that vaccine is... LOVE! ok I'll see myself out now

Can you guys make a video of Milo of Croton? Please!!!!!!!

Ted animators I love you

I am thinking the practical application is going to be a little lackluster compared to the imagination this video may have imparted in people's minds. For one, I doubt the human body can produce and retain such large variations of antibodies in effective volume. So, it may not even make sense to train against very large variations, much less every possible variations at once. It will probably be more of a "This is a template vaccine we have that is approved. This are the projected variations we will produce for in the next xx months." You're still going to need that jab annually or so, but there should less concern about untested long term effects, since these are already preemptively tested since years ago.

Isn't this the plot of Futureman?

As much as it would be great to have a vaccine to protect against everything, I can't shake the feeling that big corporations like big pharma would hold something like this out of reach or behind a high pay wall. The quote "A patient cured is a customer lost." comes to mind.

Hola

I will never look at Napoleon the same again!

A shot against everything, even you?

I wonder what the viruses would come up with if this ever becomes a reality ( ಠ‿ಠ)

The only thing i know it in this video is Napoleon thank you so much

One vaccine to rule them all

VAERS.

I think TED-Ed had a beef with Napolean.

Hi ted

这个频道中文字幕好舒服

I Never really understood what was an antibody before. Thanks, Ted Ed

Look If you had one shot one opportunity to seize everything you ever wanted in one moment would you capture it? 💩🤣

1:35

Well, not something that WE get to look forward to. Most of us will already be dead at that rate.

Lets go its early

Terrain theory.

All praise magical vaccines

I like the narrator

Couldn't it be done by genetic engineering for future generations? So that the generic programing wouldn't allow for anything in the body but those with the correct "sequence" or other identifier? Maybe even something artificially implanted self replicating that nature can't duplicate?

So napoleon is the root cause..... Britain : It's our time to take on 😁😁

AI is going to play a role in creating a universal vaccine.

captain America super soldier serum

am I the only one who watches this and starts to think that I'm infected by something?

can you bring the argument to fear of abandonment?

is FEV about to become a reality? If so I hope I make it to 10/23/2077 to see the rise of Vault-tec.

I hope,, half if not all the budget for war is allocated to health care

doctors could not save me from cancer

I think the future of healthcare is definitely nanomachines son

Rip mice 🐭

Even vaccines have face unlock

Pure awesomeness!!!!

I'd be dead before the new medical breakthrough

Poor lab mice

hi

Your animators are fantastic, but the animations in this video are cursed

6

Ask mister Burns for help

Even if it was created, it would not be released.

I’m sure there would be zero side effects at all

the last shot i need is a 12 gauge

Ah wadul

So long as it doesn't cause auto immune issues, like the current one. The threat of misidentifying parts of your own body as enemies is why the immune system is so complicated, it makes a lot of things a double-edged sword.

😮

I'll have to disagree with the last few words. We do know it's safe for the immune system to react to hundreds of antigens at once. Our immune system actually does this on a daily basis via mucous tissue or the enteric immune system. There is no relevant difference to a flu shot containing more antigens than usual. To emphasize my point: it's well known in medicine that you can administer multiple shots at once and combinations are common. We have administered them this way for decades (if not centuries) without known problems. Of course, clinical studies have to prove beneficence of any new vaccine. There is no conceptual problem though.