The Anterior Cingulate Cortex: Decoding a Mysterious Brain Region (Sense of Mind)

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Күн бұрын

The anterior cingulate cortex (ACC) is a region of the brain involved in almost every decision you have ever made. Scientists have long struggled to unify the functions of the ACC, but a coherent theory of its function now seems to be coming into view.
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In this presentation, we’ll see that the anterior cingulate cortex is critically involved in:
- Value-based decisions
- Checking progress towards goals
- Risk and reward calculations
- Integration of values
- Autonomic arousal and emotion
- Goal-directed actions
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Chapters:
00:00 Decision making and the many roles of the anterior cingulate cortex
06:26 The Anatomy and Connectivity of the ACC
11:25 Thought Experiment: Foraging For Berries
14:53 The dACC in Value-Based Decisions Involving Considerations of Time
19:03 The ACC in Checking Progress Toward a Goal
21:57 The ACC in Risk/Reward Calculations
27:39 The ACC’s role in emotion, interoception, and autonomic physiology
34:56 The ACC controls autonomic arousal and elicits emotional behaviors
41:10 The dorsal ACC Elicits Goal-Directed Actions
46:40 Summary & A Hypothesis of the ACC’s Overall Function
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Sources:
Monosov, I. E., Haber, S. N., Leuthardt, E. C., & Jezzini, A. (2020). Anterior cingulate cortex and the control of dynamic behavior in primates. Current Biology, 30(23), R1442-R1454.
Klein-Flügge, M. C., Bongioanni, A., & Rushworth, M. F. (2022). Medial and orbital frontal cortex in decision-making and flexible behavior. Neuron.
Pelliccia, V., Del Vecchio, M., Avanzini, P., Revay, M., Sartori, I., & Caruana, F. (2022). 70 Years of Human Cingulate Cortex Stimulation. Functions and Dysfunctions Through the Lens of Electrical Stimulation. Journal of Clinical Neurophysiology, 10-1097.
King, M. L. (2019). The neural correlates of well-being: A systematic review of the human neuroimaging and neuropsychological literature. Cognitive, Affective, & Behavioral Neuroscience, 19(4), 779-796.
Talairach, J., Bancaud, J., Geier, S., Bordas-Ferrer, M., Bonis, A., Szikla, G., & Rusu, M. (1973). The cingulate gyrus and human behaviour. Electroencephalography and clinical neurophysiology, 34(1), 45-52.
Craig, A. D. (2016). Interoception and Emotion: A neuroanatomical perspective. In L. F. Barrett, M. Lewis, & J. M. Haviland-Jones (Eds.), Handbook of Emotions (4th ed., pp. 215-234). essay, Guilford Press.
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#neuroscience #brain #decisionmaking

Пікірлер: 42

@bobograi3866 11 күн бұрын

Watching such a young person speaking so wisely, curious, trying to communicate a finding, gives me hope for the future of humanity

@HansBBJJ 6 ай бұрын

This makes so much sense for me having ADHD. With weaker ACC I get decision paralysis a lot, and emotional dysregulation often follows. Thank you!

@leer.watson4673 6 ай бұрын

I never heard the expression “decision paralysis” before and I just assumed I was indecisive. However, when it reaches a point when you’re struggling to decide on which toothpaste to buy, and standing in the aisle for 10 minutes, it becomes a big problem. That’s for everything.

@LeoNux-um7tg 5 ай бұрын

same I thought it was because of my childhood trauma.

@BlackMamba-ey9vm 3 ай бұрын

@leer.watson4673 for insgignificant decisions just flip a coin or make a stupid rule like "i will buy whichever brands name comes first in alphabetical order". Saves time and energy, you also feel fullfiled because you dont doubt if you have made the right choice.

@compulsiverambler1352 27 күн бұрын

Do you have ADHD as part of nonverbal learning disorder? The ACC has been found to have weaker connections to the anterior insula in NVLD, along with the rostral prefrontal cortex. Those diagnosed with ASD but not having the additional traits of NVLD (most normal IQ people diagnosed with ASD actually have all the signs of NVLD and just never get asked about the devastating non-social deficits we have, such as inability to multitask, by the shallow social-interaction-obsessed medical community), had different connection differences in the same region (the salience network). So the logical conclusion is that there are two types of ASD, and the most common is NVLD, the type which includes ADHD as part of the profile, and has this weak connectivity between the ACC and the anterior insula.

@lolabrini3758 5 ай бұрын

Dr Andrew Huberman podcast brought me here. He talked about it and then i searched for more videos and info about it. Fascinating!

@senseofmindshow 5 ай бұрын

Huberman is fantastic! Glad to have you here.

@jazzmusicfan 5 ай бұрын

Same!

@TheSubpremeState 5 ай бұрын

Me also . Life changing revelation that explains my life and other people I know. My will to live is low to zero

@lolabrini3758 5 ай бұрын

@@TheSubpremeState dont say that it is low to zero 🥺 think of all the countless millions of generations that happened to make you today! they all had the will to live and survive and thrive so you could exist today and live for the next generations to come! You are a product of countless wills to live, and a miracle!

@gives_bad_advice 15 күн бұрын

@@lolabrini3758Good point

@ljcooper60 11 ай бұрын

Thanks!

@senseofmindshow 11 ай бұрын

Oh my god! Wow, thank you so much for your generosity.

@davidaharoni9692 7 ай бұрын

I would describe the role of the ACC as generating exploratory behavior on the body or around it, evaluating the risks observed and triggering an alarm or all-well response

@senseofmindshow 7 ай бұрын

I like that perspective. Thanks for your thoughtful comment.

@georgelee6972 11 ай бұрын

Hey just wanted to drop a message saying that these are really great videos!! I really hope you get the recognition you deserve from them. Maybe there is a way to advertise them better to psychology / neuroscience students? The capacity for us to ask questions to you / Cellular Republic is a really fantastic asset and I’m sure many students would love to watch your videos if they knew of them 🕊🙏

@sarita79 6 ай бұрын

I find your videos absolutely fascinating. Thank you

@matheusmacc5111 8 ай бұрын

Man, such an Excellent job you're doing! Thx for the Videos!

@senseofmindshow 8 ай бұрын

Thank you!!

@CentaCo 10 ай бұрын

Awesome. Thanks.

@senseofmindshow 10 ай бұрын

Thanks so much!

@user-if8bi2dc3e 9 ай бұрын

Nice Video!!!!!

@DisciplinedLion 2 ай бұрын

Andre Huberman’s explanation of this to David Goggins, made me come here. Thanks to your elaboration!

@gives_bad_advice 15 күн бұрын

Ditto. I also find the article on the study that Huberman mentioned, the study his colleague was involved in.

@derosa195 7 ай бұрын

How to get help. . Dr amen identifies the ACC as one of the types of ADD . .

@compulsiverambler1352 27 күн бұрын

It is non-verbal learning disorder, which includes a type of ADHD. This condition has a different neuro profile but all the same symptoms as normal IQ autism, except a) no insistence on routines (plenty of stimming and other sensory abnormalities, just not the non-sensory "I must always sit right here on Tuesday" stuff), and b) has a bunch of additional deficits including poor navigation, physical speed control, motor skill automaticity, procedural learning and prospective memory.

@TheWtfnonamez Ай бұрын

Basically ..... If you play your favourite video game all day long, you will NOT enlarge your anterior cingulate cortex. But if you force yourself to play a NEW and unfamiliar video game every day, all day long, you WILL enlarge your anterior cingulate cortex.

@gives_bad_advice 15 күн бұрын

What if you forced yourself to not play any video games every day?

@gives_bad_advice 15 күн бұрын

this video finds a new audience if it gets into neuroplasticity, right? I want to know what i can do to influence the growth of the aCC in a way that makes me a better person. Maybe there is no such data out there, but if there is is like to know about it. like some other commenters have said, i came to this video by way of a Huberman podcast, an interview with David Goggins. in that conversation, Huberman mentions a study that stimulated, in humans, the anterior midcingulate cortex and the subject reported that he felt like he was driving toward a storm, and he had to drive through it to get to where he wanted to go. the subject was asked if he felt fear and he said no, he felt like he WANTED to go through the storm to reach his goal. Huberman then suggested that the aMCC might be developed by deliberately doing things that are hard to do, by deliberately entering into the storms in one's life, again and again, they developing that capacity. At any rate, you're was a great talk and i listened to every word. Keep up the good work.

@tarawright2650 6 ай бұрын

I was diagnosed automic neuropathy in 2003 and ADHD more recently. Ive never understood any of it, not one doctor/neurologist/cardiologist has ever explained any of it. Might someone have a direction for me to go in? I want to just function like everyone else.

@danielespinosa5948 3 ай бұрын

Don’t function like everyone else be yourself do your own thing you can study philosophy such as stoicism or you want a fulfillment guide I’ve found that it helps me don’t think you need to think like everyone else take advantage of your disadvantaged

@tarawright2650 3 ай бұрын

I am trying to find my way. Knowledge is everything. I can at least stop absorbing all of the criticism from others and realize that it's not my fault. Now I can focus on how I might function best.

@ilozeet 2 ай бұрын

@@tarawright2650 What strategies do you have so far? Sharing this information online would be an absolute game-changer.

@hawkarae Ай бұрын

Start here ❤