The CRISPR Apostle: Rodolphe Barrangou

  Рет қаралды 51,854

Science Communication Lab

Science Communication Lab

Жыл бұрын

www.iBiology.org
For millennia, humans have been harnessing #microbes to produce everything from breads, to cheeses, to alcohol. Now these tiny organisms have produced another powerful revolution - the gene editing tool CRISPR. Rodolphe Barrangou, Ph.D., was working at the food company Danisco, where he was trying to produce yogurt lines resistant to contamination. In a series of groundbreaking experiments, he helped uncover what CRISPR was, how it worked, and why it could be so transformative.
Speaker Biography:
Rodolphe Barrangou, Ph.D., studies beneficial microbes, focusing on the occurrence and diversity of lactic acid bacteria in fermented foods and as probiotics. Using functional genomics, he has focused on uncovering the genetic basis for health-promoting traits, including the ability to uptake and catabolize non-digestible carbohydrates. He spent 9 years at Danisco-DuPont, characterizing probiotics and starter cultures, and established the functional role of CRISPR-Cas as adaptive immune systems in bacteria. At NC State, he continues to study the molecular basis for their mechanism of action, as well as developing and applying CRISPR-based technologies for genotyping, building immunity and genome editing.
Producers: Sarah Goodwin, Rebecca Ellsworth
Cinematographer: Derek Reich
Editor: Rebecca Ellsworth\
Graphics: Chris George, Maggie Hubbard
Assistant Camera: Gray McClamrock
Drone aerials: Travis Jack
Supervising Editor: Regina Sobel
Field Producer: Meredith DeSalazar
Interview by: Adam Bolt
Associate Producer: Shelley Elizabeth Carter
Executive Producers: Shannon Behrman, Sarah Goodwin, Elliot Kirschner
Except where otherwise noted, this work is licensed under
creativecommons.org/licenses/b...
© 2007-2022 Science Communication Lab™. All rights reserved.
#biology #research

Пікірлер: 43
@FelixandFilms
@FelixandFilms Жыл бұрын
Phenomenal storytelling. Great story! Love his excitement for biology and science.
@scicommlab
@scicommlab Жыл бұрын
Thank you so much! We can't wait to share more of the projects we are working on.
@scicommlab
@scicommlab Жыл бұрын
We have gathered all of our CRISPR films in a playlist. You can find the playlist here: kzfaq.info/sun/PLXwMdtHQav9Yob-hq8tsATQ-ANZJKB1Kc
@H4N5O1O
@H4N5O1O 7 ай бұрын
kzfaq.info/get/bejne/m6dgdLSdst-Wc4k.htmlsi=cj1OD2FFPflnAe_H
@QuattroNeuro
@QuattroNeuro Жыл бұрын
The team that put this together should be congratulated! Epic content.
@NeonsStyleHD
@NeonsStyleHD Жыл бұрын
Well done! Great job we'll all be thankful for. Also excellent video quality.
@sdparsons
@sdparsons Жыл бұрын
Fantastic video! This channel is an absolute goldmine for exceptional content, thank you! 🙏🏼
@jf8070
@jf8070 Жыл бұрын
SOO TRUE I've been sharing almost every video to the corresponding friends and colleagues hahha
@scicommlab
@scicommlab Жыл бұрын
@@jf8070 🥰
@wandersonduartedarocha2883
@wandersonduartedarocha2883 10 ай бұрын
High-quality science. Congratulations to Dr Rodolphe and the SCL time for this amazing material.
@scicommlab
@scicommlab 10 ай бұрын
Thanks so much for the compliment and for watching!
@berguidf
@berguidf Жыл бұрын
Great video. Thanks. Keep them coming. 😊
@ruipedro9736
@ruipedro9736 Жыл бұрын
Such an incredible and fascinating story!
@juanluisclaure6485
@juanluisclaure6485 Жыл бұрын
gracias por tanto saludos from Bo
@tamashisaha2190
@tamashisaha2190 Жыл бұрын
Loved to know how it started!
@H4N5O1O
@H4N5O1O 7 ай бұрын
they sent product and company using says it didnt work so they test and find the culture is dead (he says this) and seems the clip in this video same location as in this one kzfaq.info/get/bejne/m6dgdLSdst-Wc4k.htmlsi=cj1OD2FFPflnAe_H
@AliciaSanchezIzquierdo
@AliciaSanchezIzquierdo Жыл бұрын
Que bonita manera de narrar los experimentos. Se nota su emoción y su alegría.
@lyrictiana14
@lyrictiana14 Жыл бұрын
Super cool!
@dmenace2003
@dmenace2003 Жыл бұрын
I hope you guys receive a Nobel prize like the other crispr scientists who got the gene editing ideas.
@prajwalgowdas8059
@prajwalgowdas8059 Жыл бұрын
Same question here.
@user-sn3jm6ew2j
@user-sn3jm6ew2j Жыл бұрын
Amazing
@Life_42
@Life_42 Жыл бұрын
I love the license plate!
@loganthornton8319
@loganthornton8319 Жыл бұрын
Doudna has left the chat
@H4N5O1O
@H4N5O1O 7 ай бұрын
ahem. kzfaq.info/get/bejne/m6dgdLSdst-Wc4k.htmlsi=VH5l6p7jHZp8G5D8&t=1463
@txukiki
@txukiki Жыл бұрын
Mojica
@ajadhav42
@ajadhav42 Жыл бұрын
Why can't we add CAS sequences to Corona virus o that it does not infect human?
@patisenah
@patisenah Жыл бұрын
thats not how crispr works sir
@teteteteta2548
@teteteteta2548 Жыл бұрын
Viruses keep mutating, better to change human body to react to viruses faster but that difficult due to possible off site changes and regulation
@metipallearuna223
@metipallearuna223 Жыл бұрын
Adding crispr CAS 9 geneediting to rice plants and make them less toxic to heavy metals like lead, cadmium(super phosphate fertilizers), requires biological monitoring for these heavy metals interest in .Metallothionein protein should be able to adopt crispr CAS 9 gene editing in rice plants and more basic studies have to be made in field trial by the Regression analysis, since cadmium and lead accumulate in the bones. teeth and be placentally transferred to the foeataL blood causing diseases like it a i -it a i (0ouch -ouch painful joints) i and often osteomyelitis .The W H O guidelines for Crispr CAS9 short cuts should be non-toxic.
@metipallearuna223
@metipallearuna223 Жыл бұрын
It is like production of antibodies against the human spermatozoa tail antigen and block conception, which is why corona virus is pandermic. There's no point in adding CAS sequence to corona virus, so gay to infect humans.
@Maimonides19
@Maimonides19 Жыл бұрын
You can modify coronavirus so it doesn’t infect humans but the normal coronavirus that does infect humans is still around
@metipallearuna223
@metipallearuna223 Жыл бұрын
Transferring interoceptive diaphragmatic homeostasis monitoring while getting proper feedback from acid -base balance of blood buffer strength(Michael'-Mentens enzyme first-rate substrate constant.half velocity. 1922.
@discriminated1174
@discriminated1174 Жыл бұрын
👍🇧🇩
@abcde_fz
@abcde_fz Жыл бұрын
. Better Living Through .... Science!!! Geez-o-peezies I _LOVE_ cheeses!!! .
@txukiki
@txukiki Жыл бұрын
Francis
@dieNatoren
@dieNatoren Жыл бұрын
The only fact I don’t like about this video is, that it is focused on animal milk.
@H4N5O1O
@H4N5O1O 7 ай бұрын
kzfaq.info/get/bejne/m6dgdLSdst-Wc4k.htmlsi=cj1OD2FFPflnAe_H
@so-oo6ti
@so-oo6ti Жыл бұрын
Japan is trying to discharge radioactively contaminated water into the sea, and I'm curious about this part.
@kasuha
@kasuha Жыл бұрын
Videos that spend too much time setting up the stage have obviously too little to tell us. I don't have patience waiting for it.
@bigode9743
@bigode9743 Жыл бұрын
Well, i disagree The video was perfectly passed and that was absolutely necessary to deliver that sudden stinger at the end. Must be a bit frustrating for the guy to not be recognized for the discovery of the fundamentals of CRISPR Anyways, i often find that is not about the content, exclusively, but also about how your present it. And, in my honest opinion, this video managed to be informative, funny and engaging Well done!
@jf8070
@jf8070 Жыл бұрын
Imagine being so dopamine deprived, terminally online, and braindead that you can't appreciate the backstory that led to someone's incredibly impactful worth. If two minutes disturb you so much I bet you can't even brush your teeth. Gross.
@txukiki
@txukiki Жыл бұрын
Francis Mojica christianized the sustem: CRISPR. Salinas de Santa Pola. Spain
@H4N5O1O
@H4N5O1O 7 ай бұрын
kzfaq.info/get/bejne/m6dgdLSdst-Wc4k.htmlsi=AIItqW5Agjjaf7Pz&t=911
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