Most people use these once out of curiousity, eventually you just run out of people.

My 23AndMe story... Got incredibly detailed genetic results consistent with my family history in Europe My results started getting simplified every few months They started trying to sell me family tree services My results kept getting simplified They started bombarding me with their family tree services One day I logged in I was "100% British". No nuance, no subtlety, just a blue icon of the British Isles and not a scrap of further data..... just "British". Then they lost all my personal data to hackers. My mother is a Polish Jew. Never seen such a brazen rug pull.

3:27 I know it's just an aside, but I really appreciate the FDA stepping in and basically saying "you guys sound shady" only to get out of the way when their product was proven reliable. Props to the unsung heroes of bureaucracy that keep us safe even if they don't always get it right the first time

Thanks to my 23andMe raw data I learned that I had a gene that made macular degeneration worse with zinc. Because of this my dad tried taking AREDS2 without zinc and saw noticeable improvement in his macular degeneration. His vision will continue to decline, but at a much slower rate than it otherwise would have. Thanks 23andMe!

People are probably more conscious of the risks of handing over full genetic data to companies in the age of AI, I probably would not risk it until better security is guaranteed

The central issue is that they didn't understand their niche. They were never going to be a giant ongoing concern. They should have expected an initial big surge from the novelty of the process and new market once they got economies of scale and costs controlled, used that to pay off investors, then settled into being a midrange company with at most a million or so customers a year (more if they got into other markets). Instead they shot for the moon, and now they're crashing. Maybe they'll still settle into the midrange position, just another quiet company with another market niche, but we'll see how the finances sort out. Really, this is an issue with a lot of modern companies. They see the trendlines go up and want that forever, even though both basic economics and their particular market will obviously make that fail at some point, and they keep not planning or preparing for that point.

steps to become a famous successful entrepreneur 1. marry a billionaire 2. go back to step one

I guess 23andMe are not moving past '23😂

Imagine if it later turns out the companies offering to protect you from data brokers, are in fact selling your data to more _circumspect_ data buyers all along, and TLDR has to run another video about their former sponsors.

23andMe: Me: "I don't even know who you are"

I was going to do a DNA test through this company as I wanted to know more about my ancestral background. Then I found out once this company and its competitor owned your DNA when you give it to them. They could do anything with it. I wasn't comfortable with someone possibly using it for ill intentions and not having any say with how my information was used. I changed my mind and kept it private instead. Glad that I did especially with the breach that they had last year.

I had considered getting a DNA test with this company, but they just made it extremely difficult in some countries. Their competitors are a breeze to use, but they seem to mainly be a US-centered company in terms of market appeal. Aside from medicine, they still have a multi-billion market in the other 190+ countries with the original tests.

You only need to do it once, you only need one sibling to do it, and it's only really interesting if you come from a family with a migration history - one of my brothers took it and duh, we are the northern european celts we already knew from famiky records and, well, looking at us.

“Video brought to you by Incogni” 😂

I’m shocked at so many comments saying that they never heard of this company. It was huge just a few years ago, advertised everywhere and I swear I couldn’t go anywhere without hearing or seeing advertisements.

It's extraordinary how a company based on genetics has been plagued by such inbreeding amongst it's leaders and owners. Similarly they have largely ignored markets outside of the US. Genuine collaboration with healthcare providers (Primary care and Hospitals -leading them to develop their own services.) and Ancestry has cleaned up on the genetic relationship side with 23 and mes family tree aspect being shockingly lame. Whilst taking their eye of the ball on data security which had to be the number 1 risk for the entire business. They are victim of believing their own hype.

5:43 Hi, Dr.Nick!

Hmmm it's a bit disingenuous to look at stock price during the 2021/early 2022 biotech bubble to now. Almost all biotech companies went through insane valuations and crashes, mostly due to interest rates going from 0% to 5% in a few months and investors overvaluing biotech due to the coronavirus vaccine veing developed.

I can’t think why the hell anyone would give their dna to private company.

Great video! Also I love the dress! Feeling so inspired! subscribed :)

Seems another effect of the end of free money (as it were). Higher interests rates mean investors are no longer throwing cash at anything with a flashy investment video - unless it has 'AI' in the title anyway.

Best business plan, keep it in the family...

That’s a great intro tune!! How is this song called?

Never heard of it untill now, thanks...

I'm grateful that they found I had two Irish genetic diseases from 23andme. I had loads of odd symptoms and quite a few bloodtests and I only found out later after sometimes feeling fatigued and ill I had two copies of the hereditary haemochrotosis and a copy of the Coeliacs disease. If you think you're of Irish descent, get yourself checked out!

As someone who works in drug discovery this is wild. 50 candidates is INSANE. Drug discovery is one of the most expensive processes in the world due in part to the high failure rate. Additionally patient data is sacred being subject to significant data breach or mishandling is such a death knell. I wouldn't be surprised if GSK has tried to sever their connection with 23 and me to cover their own butts.

Great to see the news on it… not much meat, industry comparison, foundation purpose/motivation, principles, comparisons of: size, innovation, papers, SWOT analysis, Eisenhower matrix, etc.

Have they tried 'surge pricing?'

Never heard of that company...

Definitely didn't do the test after reading the fine print.

It's unfortunate they are able to sell a legitimate product yet they can't be profitable. It would be interesting if they'd expand into more countries because that would provide better ancestry data. For example all the relatives I see in 23AndMe live in America when I'm positive 99.9% of my distant relatives in total actually do not.

Isn't divorce a simpler way to get rich? Companies seem too much work. Profitable companies - wtf are those supposed to be?!

It turns out most people have the same DNA as their family members and local community. Who would have guessed?

This company fell from grace fast.

Family secrets might dissuade those who know them from revealing them by publicizing their genetic connections.

If 23&me awitches to longevity research i think they can recoup losses

Will they get a bailout by the federal government?

Never heard about this company in my entire life

"the DNA of decline" you guys are absolutely ruthless 😭😭😂😂😂

i am very disappointed with this company i cant enter my subscription for months even that "THEY SEND ME A NEW PASSWORD" and lately they not even send a password BAD very bad 0 stars for this company

never heard of this company ??

This agencies should try to get more data from non Western countries, maybe they will get new customers

All the ancestry-obsessed people have already found out they have black ancestors and unalived themselves.

Best thing that could happen to this company.

What's a "Conshumer"?

When your DNA isn't considered protected medical information...

I tried 23 and me but they couldn't identify my ancestry. After speaking to customer support they sent me another pack for free to try again. So I sent my semen sample a second time and that didn't work either. And the company wonders why it's going downhill 🙄

I would love a insurance compagnie having access to my genetic data and augment my rate based on my family genetic... that would NEVER happen right ??? haha

We had a data breach. Please change your D.N.A. Sequence for future use.😅

Next video. The rise and fall of Incogni 😂

DNA term’s of ancestry is incorrect.

Their main competitor (AncestryDNA) has been far more successful. They focused on the ancestry and family history aspect rather than delving into health and medical issues.

I've never heard of 23 and Me

For everyone who's puzzled that they never heard of 23AndMe, it may be because they never entered your market, or because their marketing outside the US is poor. There are regulatory and legal constraints when you offer health-related services and charge for them, so it may be that they were delayed in entering markets outside the US, and did not promote as much in those markets. Try to figure this out: According to some of their webpages (starting at [[1]] and following links), they ship to the US, Canada, the UK, and various countries categorized as "Europe" or "International." Under "Europe" they list only Denmark* Finland* Ireland* Netherlands* Sweden* The asterisks identify EU members. So they considered the possibility of including non-EU members under "Europe," and include Ireland but not the UK in "Europe." Fine. The International list includes most other European countries. Why the unexplained distinctions between a few select northern countries and most of Europe? Like a lot on their poorly thought-out pages, it's unclear. One possibility is that they advertised and consider as "Europe" only EU countries where pretty much anybody capable of spitting into a hygienic receptacle can also speak English. Another might be that both the "Ancestry Service" and the twice-as-expensive "Health + Ancestry Service" are available in the five "Europe" countries, but that in the "International" European countries they can only offer the "Ancestry Service." West of the Russia-Belarus-Ukraine-Black Sea line, the "International" list excludes these generally recognized European countries East to West, unless I missed someone: Turkey, Serbia, Montenegro, France, and Andorra. The International list also includes many other "Western" countries. [[1]] eu.customercare.23andme.com/hc/en-us/articles/204712980-What-Countries-Do-You-Ship-To

am i missing something? why did they start talking about drug development in the middle of the video?

How can a DNA test reveal your SSN number? lol, doesnt make sense.

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I’ve never heard of this company until now 😅

:o

I honestly had never heard of this company, let alone that they were a billion dollar company, lol.

why do you keep on shouting like you're in pain?

The timing is very suspicious. Certain people clearly didn't like the result me think

23AndBLM falling? Seems like good news to me.

First of all, why is it called 23 and me? Is it the chromosomes? But it sounds like a make up brand 😊

Seems awfully similar to THERANOS Like Come on GUYS

This company fell from grace fast.

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This company fell from grace fast.