The Science And Benefits Of Methylene Blue

Рет қаралды 64,743

5 ай бұрын

Methylene blue may offer a promising solution to combat aging at the cellular level, particularly through its interactions with the mitochondria. In this video we look at the mechanism of action, benefits, and dosing of methylene blue.
#methyleneblue #antiaging #mitochondria
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Пікірлер: 496

@lindajames7759 4 ай бұрын

I came across MB about 1 year ago as I was researching cognitive decline in my husband. I bought it and he has been taking a low dose, 20 drops in 100ml water in a pump spray, twice a day. Just pumps maybe 6/7 times into the mouth. His memory has improved along with his general wellbeing. I also make pro biotics like kefir and reuteri which are phenomenal. He is now a fully engaging man again. MB is amazing 🇬🇧🇬🇧

@JonasKuehneMD 4 ай бұрын

Thank you for sharing this! There are quite a few small studies showing great efficacy of MB in cognitive decline. I am very happy to hear that this worked so well for your husband.

@kettymanno7256 4 ай бұрын

Thank you for sharing, can you be kind enough to tell me which brand you buy. I appreciate your answer so much and I am so glad you were able to significantly help your husband, the best gift is to have your mind.

@a.macdonald4877 4 ай бұрын

@@kettymanno7256 Lifeblud makes a great pharma grade brand

@TRUMP-2024-UK 4 ай бұрын

Are you Welsh?

@Ferofero8 4 ай бұрын

🤓 Hi Ketty ! A good recomendation has beeing CZTL ! Look for it ! @@kettymanno7256

@fatihosmanli5779 4 ай бұрын

Thank you very much Dr. I am 55 yok, 76kg. Heavy smoker and heavy drinker. 6 months ago I started 1% pharma grade MB with 40 drops a day. After a few weeks I was on a sailing yacht with my favorite cigar and Best bourbon. Suddenly I realized that I can not drink the damn thing. Anyway returning from the trip, I have asked to myself why am I drinking and smoking. I just stoped right there. Since then my mood was awesome. I can not recomend enough. Love MB

@JonasKuehneMD 4 ай бұрын

Thank you for this awesome feedback! Congratulations on making these amazing changes. I have noticed as well that I can now easily skip my occasional whiskey, and have a lot less cravings for it.

@MellowMornings-ox1yv 4 ай бұрын

Would you be able to supply the name of the brand? Looking into this. Glad to hear you’re doing good.

@RobinCartwright72 4 ай бұрын

Yes, what brand are you using?

@ricochet243 4 ай бұрын

Yo yo, Fati, what brand are you using?

@Blewis-Diarrheo 4 ай бұрын

I didn't know that yaks can live that long

@xenajade6264 2 ай бұрын

I'm female 44kg. Have been taking MB for 3 days, 5 drops a day in the morning and now on day 3 noticing a huge improvement in mood. Before i was struggling with intense anxiety waking in a terrible panic every day. Delighted to say I'm feeling massively better!

@JonasKuehneMD 2 ай бұрын

That is great to hear! I have observed this change in mood as well.

@chosendavis4780 2 ай бұрын

Glad u feel better 🎉

@MisterAmazingAllTheTime 26 күн бұрын

@@JonasKuehneMDDoc, hello, do u think it would help with fighting addictions? I have ordered 3 bottles of MB in hope that this would help me get rid of harmful habits.

@MisterAmazingAllTheTime 26 күн бұрын

Good to hear ur better:)

@Russ0107 22 күн бұрын

you're killing yourself with this stuff, I really hope you quit before it's too late.

@spence3141 4 ай бұрын

Been doing 40 drops of 1% MB in 16 oz filtered water with two molecular hydrogen (H2) tablets which each produce 8ppm dissolved H2 for a couple of years now. Am 71, wt 140, ht 5'7". When I was 65, I felt like 95. Now, at 71, I feel like 55. Off all meds, etc. No more pain!

@JonasKuehneMD 4 ай бұрын

Thank you for sharing this! I am looking for long term data of low-dose MB and this real

@JonasKuehneMD 4 ай бұрын

Really helps!

@spence3141 4 ай бұрын

I would love to be in some kind of study. My health used to be extremely horrible from being under doctor's "care" for decades my health deteriorated massively. Was on 15 - 17 meds daily until my doctor illegally suddenly fired me for trying to get her to reduce my pharmaceutical load for about 1.5 - 2 years and taking over 50 scientific studies on the regimen of drugs she had me on and I was trying to find ways to use natural foods to overcome my health issues. Formerly severe ADHD, Major depression, GERD, arthritis, high blood pressure, diabetes, 3 degenerated disks in lower back, constant continual pain, pain, pain, OCD, 3-8 mm kidney stones, daily headaches, regular migraines, occasional cluster headaches, huge brain fog and confusion and inability to concentrate and perform adequately, anxiety, NAFLD, lost 5" in height but have since regained a little over one inch, almost died from toxic severe mold infestation in my home, and also from Rocky Mountain Spotted Fever, and that is just the basic stuff. In the late 60's and 70's I was a hippie using LSD, heroin, cocaine, toluene, meth, and other uppers, downers and all-arounders. Am clean now. Only use medical cannabis, no other prescribed meds. Am on a healthy keto with a good amount of carnivore thrown in. Eating organic, whole, real foods, raw when appropriate, local when possible and available. My body feels GREAT. WONDERFUL, in fact. It feels like it is SUPPOSED to. AGAIN. I used to be on a swim team. My body is beginning to feel like that again, and I am ever so grateful. @@JonasKuehneMD

@zackbarkley7593 4 ай бұрын

40x.05=2 mL of 1g/100mL= .02 grams = 20 mg or 20mg/140/2.2= 0.314 mg/kg human which is about 2.2 mg/kg for a mouse which is about 7x more metabolically active than human. Is that the dose you were aiming for?

@rb9888 3 ай бұрын

where do you buy it?

@vilaolsem8350 4 ай бұрын

I micro dose this 5 days a week for past year. I found, what no one else mentions, is I can eliminate 90% of the pseudoephedrine allergy medications I need to take to breathe well.

@JonasKuehneMD 4 ай бұрын

Amazing!

@Trinityproductions777 4 ай бұрын

Thank you for mentioning this! I am researching trying to find something more holistic for my sons allergies!

@DevinaMagdalena 2 ай бұрын

I need to try this for my allergies. How many drops for micro dosing?

@dammor72 26 күн бұрын

Thank you, could you say how much you are taking?

@stephaneislistening6103 2 ай бұрын

In France the cancer doctor Laurent Schwartz swears by methylene blue against cancer.

@JonasKuehneMD 2 ай бұрын

Yes, especially in combination with red light at 630 nm

@stephaneislistening6103 2 ай бұрын

@@JonasKuehneMD What ?! Red light therapy against cancer? Interesting.. would you have some more info on this? I do already use such red light hat and pad in fact. But I had no idea it would help on this front.

@marcdupont9086 Ай бұрын

Salut compatriote, je ne suis pas chimiste sais-tu si l'ajout d'un oxydoréducteur au bleu de méthylène modifie ses propriétés chimiques à savoir sa capacité à donner des électrons?

@stephaneislistening6103 Ай бұрын

@@marcdupont9086 Excuse moi mais je n'ai vraiment pas les compétences nécessaires pour te répondre..

@gsh_0121 13 күн бұрын

@@JonasKuehneMDhas it any side effects on the kidneys ?

@psychfred 2 ай бұрын

I was hit by a car and had a TBI where I didn’t know who I was, time/days meant nothing, and I got lost in my driveway for the first three months post trauma. I used infrared light/red light every other day for over two years, walked 8 miles a day with a broken arm, ribs, bones in foot, and a messed up thoracic spine, St. John’s wort for 1.5 years and then stopped that to start MB. The improvements were amazing with this combo. The two year anniversary was April 13, 2024, and I have resumed my private psychotherapy practice at about 70% of the number of patients I was seeing prior to TBI, my ability to work with time is spotty but I know who I am. I cannot tell you how scary it was to not know yourself. Fatigue is extremely common with TBI and that is where I really noticed MB’s biggest improvement for me. I hope you discover what works well for your optimal health - Blessings. 🙏😊🌻

@JonasKuehneMD 2 ай бұрын

Thank you for sharing this amazing story. I am very happy to hear that you had such great improvement after this horrific accident. I have read in several papers that methylene blue can tremendously help to minimize damage and speed up recovery in brain injuries. What dose of methylene blue are you taking?

@psychfred 2 ай бұрын

@@JonasKuehneMD I was so happy to see your video, Dr. Kuehne, because this stuff has a myriad of uses, its safety protocols are tried and true, and it works rapidly. I started taking 10 drops, bid, and gradually increased it over 5 days to 20 drops, 1% USP MB in water bid. I stayed at that dose for about six months and then took a break to see what would happen (if I’d lose the gains upon cessation, etc). I just started to resume taking it two days ago because I gradually noticed an increase in that weird TBI kind of fatigue for over a couple of months, and have noticed an almost immediate return to functioning. It’s wonderful to find stuff that works. I very much appreciate your video and that you are getting this information out there.

@kocsogarc Ай бұрын

That’s amazing! What type of red light did you use?

@ibperson7765 Ай бұрын

@@psychfred Where do you but it doc?

@psychfred Ай бұрын

@@ibperson7765 where did I buy it? Amazon. Make sure it’s USP Pharmacy grade and read label for possible unwanted ingredients. Good luck

@4406bbldb Ай бұрын

I’m 77 and have used this about a year. I ride an electric unicycle and people often say my energy is like a much younger person. Low dose is a positive contributor. 🎉

@JonasKuehneMD Ай бұрын

That’s amazing! I used to be able to ride a regular unicycle when I was younger, but I’ve never even heard of an electric one. Sounds like you got great balance and energy.

@DWGoogleUser 2 ай бұрын

I am in Madrid. I need to pass your video through Voice AI and get it out.. One large drop of this under my tongue and I felt like someone, Lit A Fuse... Incredible cognitive awareness, animal level alertness, Extremely proactive Thinking Its like my IQ went from 100 to 200 in miliseconds.

@JonasKuehneMD 2 ай бұрын

Thank you for your feedback. I’m glad this is working so well for you. Sorry for the language barrier.

@alankaiser1851 4 ай бұрын

During the early Covid lock-down days I became depressed and, after a couple of years of suffering, decided to pursue alternative interventions, rather than the standard psychiatric ones (SSRI, SNRI, + CBT), and went on multiple plant medicine retreats. I'm a psychiatric nurse practitioner with prescriptive authority and a psychiatric social worker. About a year ago I started observing MB videos popping up on KZfaq so decided to try it. And, IT HAS HELPED! When taking it I tend to have more cognitive and physical energy, a more steady mind, and mild improvement in mood. I weigh 70 kg and take 35 mg MB most days and also take week long breaks from time-to-time. These improvements were significant enough for me to continue with MB and in spite of, what for me its biggest downside, staining the toilet seat when I'm not careful.

@JonasKuehneMD 4 ай бұрын

Thank you for your detailed comment. I completely agree that Methylene blue can significantly improve mood, cognition, and energy. I am currently taking only 10 mg most mornings. Have you started with lower doses and then moved to your current dose? I think it could be a real alternative to taking prescription antidepressants. Hopefully some providers will consider this when advising their patients.

@buck8055 4 ай бұрын

Thank you doctor Kuehne. I would be most grateful if you can respond to the following……I began researching MB over a year ago when I watched a YT by Dr. Been and decided to give it a try. I began taking 20 drops per day and stuck with it for almost a year. I would have continued but found myself in a real conundrum. My concern arouse when I read that MB might kill off a lot of our gut microbiome, which is of course hugely important for our health. At that point I was no longer certain what to believe and found myself conflicted. I stopped a few months ago, uncertain how to proceed and what information to rely on. Do you have an opinion or research you can point me towards on this subject sir? I would love to be able to continue taking MB. I still have a substantial amount of it. Thank you.. Whoops! I wrote my question before I finished the video. Naturally, as soon as I posted it and restarted the video, you went straight into addressing my concerns. I should have waited until the end. I very much appreciate your information.

@anonomous7936 4 ай бұрын

Are there side effects? It's not exactly natural so I'm curious. Thanks

@antjeschwarz7874 4 ай бұрын

@@buck8055Your concerns are understandable. Just make sure not to overdose. If your microbiome is negatively effected, you probably will become aware of. Maybe you could go back to 5 or 10 drops? ❤Best wishes from Germany ❤

@libertycowboy2495 2 ай бұрын

@@JonasKuehneMD 10mg of 1 % solution or 10 mg?

@manmedicine 4 ай бұрын

Interesting substance. In the ER, we don't use it for cyanide or CO, but I have given it for methemoglobinemia induced by topical benzocaine spray, and it worked very well. Your channel is excellent. Keep up the good work.

@JonasKuehneMD 4 ай бұрын

Thank you! Yes, it works great for methemoglobinemia although it’s interesting that at excessive doses, it can cause methemoglobinemia. I have never seen it in action in the ER. The dose I take is significantly lower than 0.5 mg per kilogram. I definitely notice increase in concentration, memory and energy. I would love to see long-term human studies at low doses.

@watchmanonthewall667 24 күн бұрын

Started MB about 3 weeks ago, 5-7 drops in 8oz cold distilled water daily (I use a steel straw since I have veneers that don't need to be blue!) I had lesions on my legs/arms/ankle skin from parasites/morgellons/insect bites gone wild/something! These have been healing up nicely. I sit in the sun for 20-30 minutes with as much skin exposure has possible and I use a portable infrared sauna about twice a week. I also noticed that my vision has cleared up and the "floaters" are gone from my eyes. Didn't notice a big jump in energy until I started a carnivore diet with grass fed beef, pastured eggs and raw cream fat--wow! I feel like DOING something again. No doubt getting off sugar and refined carbohydrates had a lot to do with the energy surge, but combined with MB, it has really kicked in. I'm in my 60's and look pretty well for my age--looking forward to many improvements. My understanding is that MB has been around over 150 years and was used in the treatment of Malaria. Wondering if there is a connection between MB ridding the body of parasite infestation and cancer being healed. Thanks for the video.

@JonasKuehneMD 24 күн бұрын

Thank you for your comment. Sounds like you’ve had amazing improvement in many physical ailments. Method blue was first used as an antibiotic against malaria. It also has antiviral functions, and has been used to treat certain types of cancer, often times together with red light at around 630 nm. Taking methyl in blue and allowing sun exposure can certainly be a good combination for skin pathologies.

@dorothydonahue4604 4 ай бұрын

I started MB about 6 months ago after seeing KZfaq videos. I am 79 and weigh 110 lbs. I take no meds and am extremely healthy in general. I had just completed a physically demanding job and was taking a rest. I decided to try out the MB at this time starting with 2 drops in a drink. after about 15 minutes I felt an amazing surge of energy and felt compelled to get up and finish my job in progress which took several hours of physical labor. I have been taking 4 drops once a day since with occasional breaks. I just learned vit c works with and enhances and counteracts the color so have added that to my morning drink. I have told others about the amazing benefits of MB. my daughter has the most amazing skin at age 54, she uses MB topically.

@JonasKuehneMD 4 ай бұрын

Great benefits at a very low-dose. Thank you for sharing this. It’s interesting that it can work even at two drops daily, which is about 1 mg.

@teresalehtonen8499 4 ай бұрын

May I ask whay product you take? Thank you

@jbrown9163 4 ай бұрын

could you tell us how your daughter uses MB topically the application ect/.?

@dorothydonahue4604 4 ай бұрын

no need to use pharmaceutical grade topically, Amazon has one that is about $12 for 3 bottles. she mixes it with a face cream to use, a little mb to lots of face cream for daytime and more mb to face cream for night. be careful though it can dye your bedding blue. I am experimenting adding vitamin c to the mix as it counteracts the blue color@@jbrown9163

@kkpaine 4 ай бұрын

Topically? Skin is blue?

@melaniefarmer75 3 ай бұрын

Started dosing 5 weeks ago. Started with low dose increasing to 20 drops per day in water with powdered Mg. I started taking MB because of intermentant virtego that was not resolving through other theraputic tx. I'm an equestrian and have had head injuries (due to falls) over the years (I ride with a helment). In addition, for 6 months prior to dosing with MB, I'd eliminated sugars and histimine foods from my diet. While eliminating these foods and practicing intermentant fasting, episodic vertigo was still occuring. Reducing neuro-inflammation continues to be the goal. MB has reduced the episodic vertigo and feeling of 'fullness' in my ears and eyes. My hearing and eyesight have both improved. Memory and short-recall has improved. Balance has improved. I feel that mast-cell activation and autoimmunity is involved in some sort of LC (long covid) capacity. Quieting down the immune system is vital and I feel MB is effective as it seems to help remove viral debris and fungal overgrowth. I'm 66 years old.

@JonasKuehneMD 3 ай бұрын

Thank you for this very detailed review of your experience with methylene blue. I think the dose of 10 mg daily seems to work for a lot of people. It’s interesting that this improved your eyesight. Could you explain in more detail what differences you have experienced? I am currently using between 5 to 10 mg daily and have significant improvement in focus, concentration, energy, and mood. I noticed that I get a lot more projects done.

@susanoconnor701 3 ай бұрын

How do we get notified of a reply to our comments?

@rayannwaldron7895 2 ай бұрын

Also, what brand do you use?

@uzayaga Ай бұрын

What was your dosage for fungal overgrowths

@PJB-To-be 4 ай бұрын

I started on MB a year ago. I had depression and felt I was aging too fast. Iam 64 and now I see and feel noticably a good difference. My hair has more brown iin it. My skin has thickened so less wrinkles. I have more energy. I take 2-4 drops in tea with a 1/4 teaspoon of vitimin C. Knocks the color blue down. I find with higher doses I get head aches. My husband just started on it. I dose him about 4 drops. He has it in his coffee without vitimin C. We'll see how it go's for him. I take it most days but but don't fret if I miss a day or two. ❤

@JonasKuehneMD 4 ай бұрын

Thank you for this great feedback. It’s amazing what small amounts of methylene blue can accomplish. I might decrease my dose from 12 drops down to eight drops. I made the mistake today to take it before my workout and noticed a slight headache and racing heart. Will take it after workout or two hours before.

@reidbounsall9098 4 ай бұрын

Excellent video, Dr. Kuehne. Thanks for doing it!

@JonasKuehneMD 4 ай бұрын

Thank you 🙏

@christopherdavis9883 4 ай бұрын

I definately think with mb, less is more. I take 20 drops (approx 10mg) in 8oz of water with added vit c to improve flavour, and drink it through the day. I had a uti that would not go (weeks). I took mb (anti bi's are only a last resort for me), and it cleared up in days; I have been taking it ever since (about 18 months), for all the above reasons stated in the video 👍

@JonasKuehneMD 4 ай бұрын

I completely agree that the lower doses are sufficient, especially if taken long-term. Also at lower doses the concern of gut Microbiome interference is extremely low.

@Hoenhighn1 4 ай бұрын

Vitamin c alters it. I cant remember how but it changes the way it works

@mayamorabito1669 2 ай бұрын

What brand do you trust for being tasted for safety and not containing heavy metals, etc. ?

@christopherdavis9883 2 ай бұрын

@mayamorabito1669 I use BLU BRAIN; it's a company based in the UK. I have been using it for a while now, and am happy with it.

@libertycowboy2495 2 ай бұрын

20 drops of 1% solution?

@theghostcore 4 ай бұрын

I appreciate your honest and detailed information and insight. I'll look into this.

@JonasKuehneMD 4 ай бұрын

Thank you! I continue to use it five days a week. My current dose is 6 mg in the morning.

@jowarren4083 4 ай бұрын

Terrific video. Very time and information efficient!

@JonasKuehneMD 4 ай бұрын

🙏

@14sasst 4 ай бұрын

Thank you for providing scientific research and evidence.

@marlinkhoshababratdeel2250 3 ай бұрын

Thank you for this good information and I started taking it couple of days and skip couple of days. I did not pay attention a lot what’s happening but I noticed sometimes makes my bowel move fast and give me a clear mind which I needed. So I will pay attention more to what’s going on. Thank you God bless.

@Ge1Ri4 4 ай бұрын

I've been using methylene blue since May 2023, and I can't be sure, because I've made a lot of changes in diet and exercise and supplements, but I do feel that my general energy levels are higher and my thinking seems to be a little more sharply focused due to methylene blue. I put 2 drops of methylene blue in my coffee every morning, and I have a half panel of LED red and near infrared lights that I use frequently, both to alleviate muscle soreness after my workouts at the gym, and to help me sleep at night (I find that getting some red light first thing in the morning helps me to sleep better at night). When I first started using methylene blue, there was no change to the color of my urine, but now that I've been using it a while, I do get the blue to green tinge in my urine. Maybe at the beginning it was all being used up to repair all the damaged mitochondria, etc, as I was very metabolically unhealthy? (I still am, but I'm in much better shape now, and continuing to make progress).

@JonasKuehneMD 4 ай бұрын

That seems like a very conservative dose and I’m glad that you experiencing positive effects even at 1 mg per day. I’m not sure what it would taste like in coffee but probably better than drinking it on its own. The LED red light and the infrared light can amplify its effect. Thank you for your detailed information!

@bugsy1254 4 ай бұрын

That’s a tiny dose. I take 4 mils at 1%. I think that is 80 drops per day. Try increasing your dose over time and make notes of any changes.

@RPcropland 4 ай бұрын

Not saying it MB or not but being attentive to your self and the associated discipline of routine does have dramatic effects on health.

@cjk248 4 ай бұрын

Have been talking MB for a few weeks now. I have noticed an increase in energy and cognitive clarity for sure. I also suffered from eczema and am pleased to say that I have 99.9% clear skin. Very pleased! I’ve been taking mine I. A capsule form so there is no taste or staining issues. I bought clear capsules and put 10 drops in the capsule that is 5mg. I am taking two capsules in the morning and one at night for a total of 15mg daily. I might add, my adult son has been able to get off his ADD medication completely taking the same dosage.

@JonasKuehneMD 4 ай бұрын

Thank you for this great information. I’m glad to hear that. This works so well for you. It’s also interesting that your son improved in his ADD symptoms. I’m trying to find publications on younger children with ADHD using methadone flu, but it does not seem to be much available currently.

@theohioshirey 2 ай бұрын

@@JonasKuehneMDI think you meant methylene blue vs METHADONE FLU, your voice-to-text writer 🤖 is picking on you 😄 (it does me too)

@King311___ 4 ай бұрын

What worked for me: For physical energy, intrusive thoughts: benfotiamine, ttfd, sulbutiamine For ocd, mood swings: Lithium orotate

@caiomherigpa 2 ай бұрын

considering using this in a chronic Lyme protocol! It’s new in my research so thank you for sharing this information now I see how it makes sense 🙏

@JonasKuehneMD 2 ай бұрын

Great, I think this might be very helpful here.

@sylvialenz84 4 ай бұрын

Your English is excellent!!!❤

@christinec1111 4 ай бұрын

Taking for a month now orally with a (day off) break in between each week.. Having a few days off.. Certainly noticed after only a month my grey hair (on my head) hardly coming through !!! Fab

@JonasKuehneMD 4 ай бұрын

Amazing! Thanks for the feedback.

@wayimp 4 ай бұрын

I've been taking it an a capsule form I got off Amazon, and I've noticed more energy and a more productive disposition later in the day, so I don't burnout working in the afternoon or evening.

@JonasKuehneMD 4 ай бұрын

I have noticed that as well. Thank you for sharing.

@bluesky7704 4 ай бұрын

I have an autoimmune an skin issues I started MB and my skin is currently 90% cleared up. I have also dropped a few pounds. I dose 2 to 4 drops

@JonasKuehneMD 4 ай бұрын

Amazing! Thank you for sharing!

@lalameeralalameera7349 4 ай бұрын

Is it psorisis you were suffering from

@bluesky7704 4 ай бұрын

@@lalameeralalameera7349 it was more in the order of scleraderma or hardening of skin patches.

@bluesky7704 4 ай бұрын

@@lalameeralalameera7349 scleroderma

@bluesky7704 2 ай бұрын

@@lalameeralalameera7349 scleraderma

@happy_dose 19 күн бұрын

Thank you doctor so much for sharing the information.

@JonasKuehneMD 19 күн бұрын

My pleasure

@ChevySS1968 4 ай бұрын

Great vid, thank you!

@nicolettetheunisz9155 3 ай бұрын

started taking it recently ,thank you for the information. I think it indeed helps with my mood and general energy. 8 drops per day.

@JonasKuehneMD 3 ай бұрын

Thank you for listing the dose that worked for you. It is amazing how little we need sometimes to have a very good effect.

@sylviarod6308 24 күн бұрын

I will be starting these jobs soon for cognitive clarity. Improvement with iron issues. I look forward to overall improved health. Thank you for providing information and experience. And education about these drops.

@JonasKuehneMD 24 күн бұрын

Thank you for your comment. Methylene blue has helped me greatly with cognitive function, energy, and ‘mental clarity’ if that is a term. I’m currently using 10-15mg daily in the form of tablets from best365labs. There is a link in the description for a discount if you’re interested to try this. Otherwise drops work as well. They’re just more messy.

@erwinrogers9470 4 ай бұрын

Great information👍

@1rocknroy 4 ай бұрын

I started out with 1 drop of the standard Methylene Blue, 1% USP (Pharmaceutical) Grade in the morning. The first day I felt somewhat energized but after that whenever I took the 1 drop I felt very tired so I stopped it. After hearing this video and reading the comments I will take 10 ( 1/4 of the dose for my 84 kilogram weight ) drops in the morning.

@JonasKuehneMD 4 ай бұрын

You could even start lower, like 5 to 6 drops, given of course you are cleared to do so. It’s interesting how some people have good responses with very low doses.

@Deltonization 2 ай бұрын

I have been taking 20 drops per day for about 2,weeks now. I immediately noticed the Mental Clarity. I also noticed that I started remembering small events from my childhood which was surprising. But the most amazing thing has been my Sarcoidosis Rashes clearing up. Which is something only high dose prednisone would do. And that was just the 1st week. I’m excited to see what the future holds!😊👍

@JonasKuehneMD 2 ай бұрын

Thank you for your feedback. That is great to hear. A lot of people have noticed fantastic benefits and the doses do not have to be huge.

@mystrength5640 4 ай бұрын

Thank you, Doctor. Will look into this in time, will have Blood test done. 🎉

@JonasKuehneMD 4 ай бұрын

👍

@DaboooogA 4 ай бұрын

Great video thanks

@ethereumrise7860 4 ай бұрын

Can you do a video about mold toxicity, please 🙏🏻.

@Imana23 4 ай бұрын

I take 5 drops when I get sick . I also take full spoon of vitamins c and it does help. The symptom are not as bad and usually 2, 3 days without high fever and I am back to normal. During Covid doctors in Russia would recommend taking it or inhaling. But as they said yo have to do it the first 2 days of the sickness. I also give it to my 8 year old when she is getting sick. When I learned it has anti-aging properties I started to add it to my face creams. 2,3 drops for 1 fl. ounce jar. It doesn’t stain your face when you don’t add too much.

@JonasKuehneMD 4 ай бұрын

Thank you for your comment. I have to try out adding it to. That sounds interesting.

@antjeschwarz7874 4 ай бұрын

Thank you for this video❤. My MB is on its way. I am going to use it together with DMSO. Will start with 1x 1:1 Drop BM:DMSO per day. Will go on with 2x 1:1, 1x 2:2, 2x 2:2, 1x 3:3 - up to 2x 5:5 MB:DMSO. 65yo there is something to improve healthwise. Already take D, K2, Magnesium, MSM, Bor, Jod, alpha-liponacid. Am going to enhance with selen, zink, Natokinase, multivitaminsB, just in case. All the best to all of you❤

@JonasKuehneMD 4 ай бұрын

Thank you for the detailed feedback! Please keep in mind the contraindications like G6PD deficiency. I find that a low dose of 5-6mg daily works great for me. This is not medical advice of course.

@Allyourbase1990 2 ай бұрын

I just got mine today and am drinking it now . I think next time I’ll make my own with powder . I’m excited to see the benefits

@JonasKuehneMD 2 ай бұрын

Great! I found the easiest way is to take it in the form of tablets. I work with this company currently: www.best365labs.com/?ref=Jonas Code: Jonas10 for 10%off

@aliciaholte2525 4 ай бұрын

Shoulder injury of eight months was gone after four days of taking methylene blue 10 drops morning and night. A long term upper back soreness also became not noticeable and has never returned.

@dr.gregoryweisswassernd7251 4 ай бұрын

This is interesting. I’ve heard some of my patients using MB lately. I’m trying to become better educated on it. It was not something we learned to use clinically in medical school and I’ve never heard it used that way in any of my continued professional trainings. There seems to be some concern with toxicity be it acute or long term. However the comments here show that many people are having fantastic results. I’ll have to research more and if it is as good as it sounds for patients health maybe I’ll have to bring it to my fellow Naturopathic Doctors.

@JonasKuehneMD 3 ай бұрын

This was my experience as well. I was only familiar with methylene blue from the emergency room, where it was used intravenously in cyanide or carbon monoxide poisoning cases. Using it as a nootropic requires much smaller amounts in my opinion. I currently use only 6 mg a day, five days per week. This is way below the safe range of 40 mg to 320 mg for my body weight. Well, I could find know long-term studies at these doses, it is difficult to imagine toxicity here.

@matordonez 3 ай бұрын

Thanks for this video! I will start to take it I spoke with my doctor about that

@JonasKuehneMD 3 ай бұрын

Thank you for your feedback! Much appreciated

@matordonez 3 ай бұрын

@@JonasKuehneMD If I weigh 143.3, how many drops would you have to take?

@EvolutionFitness369 4 ай бұрын

Thank you.

@MyLove-uj8zi 4 ай бұрын

I take 4 or 5 drops is enough. Why would I more when such a small amount works so well 6 drops made me a bit jittery. I also use it on my skin, with vitamin C.

@angelinavitaleco9640 3 ай бұрын

Great video. ❤ -Angelina Vitale

@JonasKuehneMD 3 ай бұрын

🙏❤️

@Chuv777 20 күн бұрын

The only previous experience I've had with Methyline Blue is for use with outbreaks in aquaria such as fungal infection or to treat Ich/white spot so I was interested to learn of its role in this context.

@gulsumkr4486 4 ай бұрын

Thank you

@grilsegrils9330 4 ай бұрын

In my country you can't find it easily outside of the pharmacy. And the intravenous type from a pharmacy needs prescription and costs a lot of money too. I wonder how doctors respond if you ask for prescription. Probably rejections, as they don't want to do malpractice

@jdram58 4 ай бұрын

Pretty good n simple explaination and ideas how to use it as Im trying it myself but I am concerned about the gut micro biome as well but have a product I used from Dr Gundry that is pretty decent.

@JonasKuehneMD 4 ай бұрын

👍

@user-mc8gd2bp2r 4 ай бұрын

I have been taking MB for 18mths as a maintenance dose for better health and to help with inflamation. About to 60yr and feeling 40yr! I take 10/12 drops 2x daily in water. I feel so good on it that I have not yet taken a break (apart from a few days whereby i noticed my joints aching again). Wonder if i should? The dose i am on keeps my joints completely ache free. It is amazing! I also believe it is doing me some good in ways i cannot visibly see.

@JonasKuehneMD 4 ай бұрын

Thank you for this great input. We do not have great data on longtime low-dose use of MB. I am wondering why you are using it two times per day. I started out that way, but noticed that the night dose disrupted my sleep slightly. I am currently only taking it in the morning at about 12 drops 4 to 5 times per week.

@user-mc8gd2bp2r 4 ай бұрын

@@JonasKuehneMDas recommended in Mark Sloan's book and it has caused no issues. I started out with really small doses and it work miracles so I never increased it or worked out the body weight:dose ratio. I feel that I have room to move on the dose should I ever become unwell. It helped with my sleep immensely right from the start. Only getting up to pee which is normal for someone who hydrates well and is my age. Oddly, the pee no longer appears blue! My gut health also appears to be good although I do eat a natural, healthy diet as much as possible. Low in sugar but moderate in everything else - meat, dairy, alcohol (wine & beer), eating out on occasion too. I cannot emphasis enough that by far the biggest improvement was my hip joint pain after walking and waking, my elbows bones were tender to touch and shoulders grinding making sleep a little uncomfortable - all GONE!

@fourthtunz 3 ай бұрын

I’m 61 and I started taking it for energy and joint pain. I think I want to try taking it twice a day as I feel the pain comes back after dinner and I feel my energy drop. I’ve only been taking it about five days and just worked my way up to eight drops in the morning. Thanks for the great video.

@erwinrogers9470 4 ай бұрын

Love it🔥👏

@Intwodeep902 4 ай бұрын

Gr8 video!

@JonasKuehneMD 4 ай бұрын

Thanks!

@squirlmy 2 ай бұрын

interesting, I heard of Methylene Blue for health about a dozen years ago, the "nootropics" movement was just starting. Entrepreneurs were starting online stores to sell it, because, although cheap, the main common source was at pet shops as a substance for treating fish illness. Obviously this wasn't pharmaceutical quality and people were naturally hesitant to take it as a supplement for themselves, so, from discussion boards of supplements, an online market was born. Also, I've not head of it used in psychiatry, in fact nearly the opposite: it was tried as a dye for pills and tablets in research, including for placebos, but interfered so much with results of studies of antidepressants, that pharmaceutical research became careful to stop using it! Actually while I found results fairly good, I also wanted to try various other antidepressants and supplements, so stopped using it for similar reasons

@JonasKuehneMD 2 ай бұрын

Yes, I have heard of people using the industrial version of methylene blue that is used in aquariums. The problem with these compounds is that they are full of heavy metals. This is the main difference between pharmaceutical grade and industrial grade. It has been used in psychiatry with good results, but since it is obviously out of patent, there is no big pharmaceutical company behind it. pubmed.ncbi.nlm.nih.gov/31144270/

@susanoconnor701 3 ай бұрын

This is so well presented. Thank you! Can you speak to taking it along with Adderall? That’s not exactly an SSRI and I don’t know if it affects serotonin as an SSRI would do.

@JonasKuehneMD 3 ай бұрын

Thank you! Method in blue has been used to treat ADHD, often in combination with caffeine and theanine. When it comes to antidepressants, methylene blue in higher doses is contraindicated together with an SSRI.

@JonasKuehneMD 3 ай бұрын

Methylene blue - autocorrect 😁

@ivecomrie4555 Ай бұрын

Same two dozes at ten drops a day , feeling good attention is up and feel more energetic body and thinking wise

@JonasKuehneMD Ай бұрын

👍

@Aidenjh11 4 ай бұрын

Which suppliers have you all (in the comments) found to make safe and effective MB?

@DG-dy4tv 16 күн бұрын

I mix lemon juice liberally with my methyl blue water. It helps a lot.

@dip4fish 4 ай бұрын

Now 57 yo. Under 20 to 40 drops of MB 1%for about 2 months , some time i think i shouldn't tinker with my health, some time on the contrary i think i should take more.

@antjeschwarz7874 4 ай бұрын

MB seems to be best for health and very save on the lower dosage. More does not help more. ❤

@gerardmoate7009 3 ай бұрын

I suffered from Lyme's Disease for many years , Not able to consume Red meat as it would cause anaphylactic shock, and hives, ...NOW ❤ CURED thanks to Methylene Blue, same rate as you suggested, increasing one drop per day for 30 days. - Blessings ❤ Thankyou Jesus. Way Truth LIFE.

@JonasKuehneMD 3 ай бұрын

Amazing! Glad to hear this is working so well for you.

@gerardmoate7009 2 ай бұрын

Thankyou brother, keep UP the good work.

@kocsogarc Ай бұрын

I also have Lyme disease for 25 years. How many drops did you use?

@paul9120 4 ай бұрын

I’ve been looking everywhere locally for this stuff and have not seen it at all anywhere… Walgreens, Walmart, CVS, and Rite Aid

@JonasKuehneMD 4 ай бұрын

Amazon has USP grade methylene blue

@mizzmention8555 4 ай бұрын

@JonasKuehneMD Hi Dr l just watched a video that said the mb bottle should be marked BP 73 for authenticity are you saying its fine as long as its marked usp grade? I've skipped lots on amazon marked usp lol

@amberfoster3285 26 күн бұрын

I had an improvement in my blood sugar not dropping so low and body aches disappeared after a month.

@JonasKuehneMD 26 күн бұрын

Great! Glad it’s working well for you.

@nieuweabnormaal5869 4 ай бұрын

And keto eating also increases the number of mitochondria I understand. Combined with methylene blue is good I think. Niot only the tongue is blue, but also everything it touches. And the toilet bowl plastic parts will be stained. I can usually remove with vitamin C powder combined with vinegar (acetic acid is catalyst for removal), at least it removes the color. Then I clean with water and a soap product to remove the decolorize methylene blue.

@kscg3776 2 ай бұрын

Question: I have a colostomy (from diverticulitis blockage emergency surgery) and reversing on May 23, 2024. I can’t seem to digest steaks or heavy meals too well, lost 30 lbs. to 107 lbs., but was always skinny. They doctors say take more fiber, but have learned that is not good. Do you think MB might help with digestion or my condition now OR after reversal (healing wound will take 4 to 6 weeks at home)?? Other history: About 8 years ago I had a level 3 spinal fusion and 2 years ago, a hip replacement (dog tripped me on stairs), then I had the emergency Colostomy blockage surgery last August - they had me on antibiotics for UTI’s for 8 months before the ER Colostomy because of a recurrent UTI, but actually, at Urologist, they missed the large kidney stone that had been causing the UTI’s (they found during my ER surgery for the blockage), and took this kidney stone out after the blockage surgery manually with a stent. Then, this last XMAS in hospital for scar tissue blockage. .… just FYI, in case history matters. Barely in hospital or sick before all this started (very healthy before I was 60). Now 68, soon 69. I feel all those antibiotics have really messed me up - they loaded me with antibiotics again in IV’s at hospital! I have started on a good liquid vitamin and Saccharomyces Boulardi probiotic with MOS a prebiotic rated high for colon issues (sold on Amazon) just last week. I see you answer most inquiries, so thank you so much!

@JonasKuehneMD 2 ай бұрын

Thank you for providing this detailed information. I’m sorry to hear about all the medical issues you are having. Methylene blue will in my opinion not improve digestion. I would also be concerned to start any medication prior to your next upcoming surgery. you could ask your surgeon if a supplement of digestive enzymes may be helpful in better processing the food that you eat. increasing your water intake within reasonable limits may also help. Antibiotics can be a tricky thing. Often times they are necessary,short-term, but it is important to select the correct ones to prevent complications.

@jdolson4092 4 ай бұрын

I have been taking methylene blue for almost a year now, and like you have experienced the cognitive benefits of clarity, recall and elevated mood. I started out taking 10 drops in the morning, and have now started taking an additional 10 drops in the evening no Negative affects. Haven’t really paid too much attention to my skin or hair. I tried to take it on an empty stomach an hour before or after eating, and have also read to avoid taking while drinking liquids with caffeine such as coffee because it lowers its effectiveness. Do you have any opinion about taking on an empty stomach or avoiding combination of caffeinein the blood system?

@JonasKuehneMD 4 ай бұрын

Caffeine is a diuretic and may lead you to excrete MB faster. I usually take it right after a meal because it does bother my stomach a bit if I take it between meals. I don’t think that the absorption will be significantly influenced with food in this case. I am taking the same dose, but all at once after breakfast in the morning. So 20 drops or 10 mg.

@dip4fish 4 ай бұрын

@@JonasKuehneMD by the way , is mb a diuretic itself?

@ironmurs6903 4 ай бұрын

Thank you Dr Brad Pitt. Appreciate you

@JonasKuehneMD 4 ай бұрын

❤️😂

@samirdreamalot 4 ай бұрын

Hey Doc. I'm concerned about the counterindication with Buproprion. Will 20 drops/day produce adverse effect with 150mg Wellbutrin XL?

@JonasKuehneMD 4 ай бұрын

This is definitely a good question for your treating physician. Bupropion, or Wellbutrin is a dopamine and norepinephrine reuptake inhibitor. It tends to interact with stimulants. While methylene blue is not classified as one, it certainly has stimulant properties in my opinion.

@samirdreamalot 4 ай бұрын

I'll keep you posted. haha! @@JonasKuehneMD

@grilsegrils9330 4 ай бұрын

Non-medical methylene blue may contain to high arsenic levels. Plus the dosing is crucial as it is a hormetic substance

@JonasKuehneMD 4 ай бұрын

Correct. It needs to be USP grade. Otherwise it will contain a lot of contaminants, including heavy metals. Oral absorption is between 60 and 90%, so extremely high. Given that for most indications to dose does not have to be very high, IV administration should only be used in the hospital for specific indications.

@0n596 4 ай бұрын

Good news! How to take it, oral is clear but how often and what amount is recommended? I Have terrible arthritis in my thumb joint (already had 5 times RSO) and my lower back L5 / S1. Can it help ?

@slvclw 4 ай бұрын

Take tumeric tea morning and night with butter and milk in it to help your joints and inflammation

@phoenixrising4762 4 ай бұрын

Quit caffeine and alcohol which are diuretics and deplete synovial fluid in joints

@bugsy1254 4 ай бұрын

The carnivore diet will clear up arthritis.

@huviba5826 4 ай бұрын

Probably you have Iron Overload (high ferritin, transferrin saturation)

@micdargis 4 ай бұрын

I’m taking MB from 10 months now, 15mg every morning. I was on Addevrall for 15 years, thanks to MB I don’t need anymore. One question, I remarked that I’m supporting much normally the alcool that before, before my talking was affected with the first drink, do you have any explanation about it?

@JonasKuehneMD 4 ай бұрын

It’s possible that methylene blue neutralizes some of the inflammatory and toxic effects of alcohol, that are commonly associated with feeling the effects of alcohol. I cannot provide you with an exact mechanism here, and regardless alcohol will still do damage.

@Ferofero8 4 ай бұрын

☹️☹️☹️ NEVER ! Drink & drive ! 🥸 NEVER !

@RPcropland 4 ай бұрын

@@Ferofero8I find it fun and tend to drive better since I don’t cut people off run red and drive over the speed limit. When drunk I slow down to drive like a “normie” because I don’t have total awareness like I ussually do😢.

@scottg429 Ай бұрын

I tried the earth harmony brand and very slowly worked my way up to 15 drops a day but started getting light headaches and other symptoms of seratonin syndrome. So I stopped for a few days and tried again. Now I have those same symptoms even at 3 drops a day. I’m not taking any contraindicatiors. The earth harmony brand is pharmaceutical grade but has something called liquid gold which the BpH brand doesn’t. Do you think I should switch to BpH ?

@JonasKuehneMD Ай бұрын

I am not sure about the liquid gold ingredient is. A very low-dose of a simple methylene blue either from BpH or the tablet form from best365labs could be worth trying to see if these symptoms recur.

@laserhobbyist9751 Ай бұрын

30 mg a day oral, no problems. At 66 was beginning to have memory problems, all cleared up when also taking 2 grams a day Magnesium L-Threonate.

@JonasKuehneMD Ай бұрын

Great combination! I’m glad this is working well for you.

@mimimcdee7052 4 ай бұрын

Hello Doc - Just found your site tonight ! Thanks for posting this video as well as the one on the mitochondria and both are superb I have 2 questions for you... I bought MB to use for my traumatic brain injured 40 yrs. old son, for my husband who is bi-polar and on Lithium and for my met. lung cancer and MS, which I heard will help all of these. Since conventional doctors do not want to even hear you mention anything outside of the box of the 'financial' model.... *Do you have any opinion on someone who is BI-POLAR and well controlled on Lithium ? *Do you have any opinion on the benefits for CANCER ? Any thoughts would be extremely appreciated.

@mimimcdee7052 4 ай бұрын

Thank you doctor for responding to my comment. I hope I didn't put you in an awkward position with the questions I asked. If so, let me know that you 'can't give advice'. Otherwise, I look forward to what you have found in your research.

@JonasKuehneMD 4 ай бұрын

Thank you for your kind words! Methylene blue has been used in psychiatry for mood disorders and psychosis. I am not sure how it compares to conventional medications here. Also very important to discuss any changes with the treating physician. Lithium, if given in the correct dose and levels are monitored Regularly, is a good medication, but can have a good amount of side effects as well. Methylene blue has positive effects on the mitochondria. I have not seen much literature on MB in the treatment of cancer. Cancer cells have malfunctioning mitochondria, and produce energy by simple fermentation. It is therefore less likely that MB supports these cells. It should, however support the cells of the immune system, which may help decrease the number of cancer cells. These are of course only theoretical assumptions.

@mimimcdee7052 4 ай бұрын

THANK YOU , YOU ARE VERY KIND WITH YOUR TIME AND EXPERTISE, and I do greatly appreciate it. My husband will talk with his doctor about it, and I have talked with my GP, but he is not at all interested.@@JonasKuehneMD Therefore, I am on my own, and assumed that MB would help repair what's left of the 'good' mitochondria and thereby improve the immune system to help take down the cancer cells. I will be incorporating other remedies such as B-17, infrared light and Lifewave patches to help the stem cells, among other beneficial things like berberine. I am so thankful that you've spoken of Dr. Seyfried, he is a wonderful man who truly cares and is not afraid to speak the truth about what is going on. If all doctors could be like the both of you, we would have no health issues to speak of. God Bless you !

@thecharlesjeffrey 2 ай бұрын

I’ve been taking MB every day with a few off days here and there for about about 6 months, Ive gone from doing 8 drops to just doing one filled pippet and squirting the whole thing out in water, I only really take it in the mornings guess I feel a bit better / clearer but I also am not sober dont smoke generally eat well and exercise. The fatigue I get is mainly coffee / sugar related I think so yeah. I get slightly concerned about the unknown side effects, but tbh I’ve been fine so cant complain x

@JonasKuehneMD 2 ай бұрын

Thank you for your comment. This is a similar dose to what I am taking currently. I have switched from the liquid to tablets because I found it too messy. While there are no long-term studies published that I could find on low-dose methylene blue long-term, many people have commented using these doses for several years without reporting any adverse reaction.

@thecharlesjeffrey 2 ай бұрын

@@JonasKuehneMD good to know any tips on curbing sugar cravings hit me up hahha ❤️

@teresalehtonen8499 4 ай бұрын

Dr, could you please tell me where to buy safe pharmaceutical grade methylen blue ? I live in Europe. Thank you.

@JonasKuehneMD 4 ай бұрын

Kopp Verlag Store Methylen Blau on Amazon.de seems to be a pretty good product.

@lauralauren6432 4 ай бұрын

I Will take some of my horse

@margottfon330 4 ай бұрын

))💓Question: do you think it helps to Chronic Fatigue Syndrome..., CFS?? TY))

@rdallas81 4 ай бұрын

Yes.. I have CFS. I use MB. Pharmaceutical grade

@JonasKuehneMD 4 ай бұрын

I have not seen any studies that specifically addressed this. I could see this being helpful though, as it certainly increases energy levels and optimizes serotonin.

@Dogman3690 22 күн бұрын

Hi, I experienced the same effects as you took about 15 drops for 2 years then raised it to 20 drops but sometimes I forget to take it.

@JonasKuehneMD 22 күн бұрын

Thank you for your comment. That is about the amount that I use which is 10 mg daily. Sometimes I use 15.

@carloscarion1748 3 ай бұрын

I’ve been using Methylene blue for some months I would say since the last summer and I found that it has helped me but I am still in the experimental stages I am not completely aware of its advantages so I’m just kind of moving along I was taking a lot of drops in the beginning like 20 drops 25 drops in one sitting now I’m only taking about 10 drops and I’m wanting to see how that bodes for me

@JonasKuehneMD 3 ай бұрын

It’s interesting, that even very low doses seem to have great effects for most people.

@carloscarion1748 3 ай бұрын

@@JonasKuehneMD That is actually what I’m wanting to see whether taking a much lower dose would be more advantageous or just as advantageous is taking a larger dogs I don’t have any particular Melody at this point in my life so maybe it would just make sense to take a smaller dose and maintain, if you know what I mean thank you for your response, this is a good article

@qwertz202 3 ай бұрын

Do you think it's dangerous to take during summer? I read that red light (which sunlight has lots of) can make it more reactive and cause oxidative damage and deplete antixoidants

@JonasKuehneMD 3 ай бұрын

Red light at 660 nm has been studied in conjunction with methylene blue to treat cancer amongst other diseases. Pathologic cells and organisms will be selectively targeted here.

@vincam4674 4 ай бұрын

Dr. Just a question I take MB for colds a flu and it work really well by taking 10 drops 3 times a day for three days and it removes about 90% of symptoms if caught early. My question is I notice taking it with Soda water reduce dramatically the stain in my mouth, I haven't take it with soda water for cold or flu, will the Soda water reduce it's effectiveness?.

@JonasKuehneMD 4 ай бұрын

It should not reduce the effectiveness.

@fionmor4893 4 ай бұрын

use a straw

@carloscarion1748 Күн бұрын

How about something like methylene blue interact with ho hu wu?

@RobinCartwright72 4 ай бұрын

What brand do you recommend? Is there a way to test MB to see if it’s authentic?

@JonasKuehneMD 4 ай бұрын

I am using the bottle you see in the video. It needs to be USP grade.

@YouButter 3 ай бұрын

@@JonasKuehneMDty

@warriorpoet9629 4 ай бұрын

I am 67 , overweight, drink too much. Liver issues. But my diet is relatively ok, no sugar. I have MB and made up a 1% solution but I cannot seem to nail down the best dose. I think I am taking too little ( 20 drops) should I increase it please. I need to do something asap as I can feel my health failing quite rapidly. I feel like I am living with the flu on a daily basis. I am unvaxed btw. Thank you for helping people with your videos.

@JonasKuehneMD 4 ай бұрын

It sounds like you have a lot of inflammatory issues due to your weight and alcohol intake. I would suggest to cut out simple sugars and processed foods, decrease alcohol intake significantly, and make sure you have adequate protein intake. I would check for metabolic health with HgA1c + fasting insulin, ideally with your PCP. You can also get access to labs through online services (e.g. life extension labs). As for methylene blue, it has anti-inflammatory action, but may not be sufficient on its own. Cannot give advice on medications or dosing here, but I am taking less than that. Also, nice bike!

@warriorpoet9629 4 ай бұрын

@@JonasKuehneMD thank you so much for taking the time to reply. Yes the bike is pretty damn nice….

@kkpaine 4 ай бұрын

@@JonasKuehneMDinterested in labs w/o docs who never order what you need. Any names of labs that will process patient requests?

@fourthtunz 3 ай бұрын

@@kkpaine life extension has low cost lab tests, you still have to have somebody draw your blood but it’s a lot cheaper than a lot of the labs charge

@chrisjones-rd8it 4 ай бұрын

right

@CAQM3737 4 ай бұрын

I am not sure why but when I take in the evening I get so sleepy. Any concern about that? 0.5 mg per kg; half in the morning and half dose in the evening. I have no complain about taking in the morning.

@JonasKuehneMD 4 ай бұрын

For me it’s too activating to take at night. I am taking only 6mg in the morning (0.075mg/kg). Did you start out at a lower dose and then increased?

@caribbeanjack Ай бұрын

Im currently on antibiotics as i got septic bursitis in my knee. A friend told me taking MB right now with 10mg of copper rubbed into the skin. Is this safe? The antibiotic i am currently on is Levoflaxacin

@JonasKuehneMD Ай бұрын

I cannot give medical advice on this platform, but methylene blue itself acts as a mild antibiotic. According to literature, it does not interact with levofloxacin.

@caribbeanjack Ай бұрын

@@JonasKuehneMD Thanks for your reply and information

@marlinkhoshababratdeel2250 3 ай бұрын

I use one gallon and put the powder blue just a little bit and I drink it every two days or three days so I don’t know if I’m doing right I follow the instruction

@JonasKuehneMD 3 ай бұрын

I would suggest to use a premixed formula. It is very difficult to dose the powder correctly. In general, I don’t think you need to start with anything more than 5 mg. This is of course not medical advice.

@tiffanyk7514 4 ай бұрын

Would people with the MTHFR mutation be able to take methylene blue safely?

@JonasKuehneMD 4 ай бұрын

The molecule of methylene blue does not need to be changed or methylated. Therefore, I don’t see any issues.

@TC-mf1cq Ай бұрын

Please do a video on drugs and supplements that can lead to serotonin syndrome when taken with MB. I was taking sea buckthorn with it and was high as a kite. I looked through my other supplements, which included boron, and that increases serotonin too. Then I discovered that creatine, which I was also taking, also boosts serotonin. Could the serotonin effects in these supplements lead to serotonin syndrome, or is it only SSRIs?

@JonasKuehneMD Ай бұрын

The increase in serotonin from supplements is very modest. In the literature, I did not come across any issues here. Taking higher doses of SSRI’s is more likely to cause a problem with MB if a high dose of MB is taken. In my opinion, doses up to 20 mg daily of MB are very unlikely to trigger serotonin syndrome even in the presence of an SSRI. This is of course, not medical advice and you should always consult your primary care doctor if you are taking an SSRI or other medication to check if MB is safe for you.

@TC-mf1cq Ай бұрын

@@JonasKuehneMD That's reassuring. Thank you so much.

@wc1957 3 ай бұрын

Methylene blue helped change my life.

@JonasKuehneMD 3 ай бұрын

Amazing. What were the most profound benefits for you?

@wc1957 3 ай бұрын

@@JonasKuehneMD I've experienced a major impact in wellbeing. I usually take 10-30 drops per day. Major improvements in energy, cognitive function, and positivity. I have also used it topically on my foot after a foot ulcer. It might be too early, bu in combination with daily infrared and healthy light activities my hair has started to grow back.

@wc1957 3 ай бұрын

@@JonasKuehneMD similar to a comment below, I smoked pot for years and once I got on the MB program it's as if the addiction just stopped. I had no interest in smoking anymore.

@user-rz4xd9cu1v 28 күн бұрын

❤

@shantinicole6493 3 күн бұрын

I’m having some issues converting dosage. My son is 2 years old and weighs 14.6kg how much should I give him according to the recommendations?

@JonasKuehneMD 3 күн бұрын

I strongly suggest to consult with your pediatrician prior to giving MB to a young child.

@angelakay808 4 ай бұрын

Anyone have the chest pains when taking this? Trying to find out if they go away or if I just can’t take it

@JonasKuehneMD 4 ай бұрын

Chest pain should always be taken seriously and followed by discontinuation of the supplement as well as contacting your physician. In high doses and if you have a G6PD deficiency, methylene blue can cause methemoglobinemia which can present with chest pain. However, low-dose of methylene blue are also used to treat methemoglobinemia.

@hagmei 4 ай бұрын

For Bartonella it is recommended to take 2x50mg daily Which is 200 drops at 1% MB, right?

@JonasKuehneMD 4 ай бұрын

200 drops is 100 mg. In my opinion a fairly high dose. It is of course still below the recommended safe doses in the literature.

@jasonjamesbradshaw 22 күн бұрын

Im glad if people are getting some positive effects from this, but I tried it for a while and got zero results 🤷🏼‍♂️

@JonasKuehneMD 21 күн бұрын

I’m sorry to hear. What dose were you taking?

@bh9262 3 ай бұрын

How do you take it? Mixed with water? So if i'm 72kg it would be 36 - 144 mg per day? Since one drop is .5mg I would need 72 - 288 drops for one max dose? Why would you take 4mg per kg when you said it's .5 to 2 mg per weight? You would be 40 - 160mg day based on the dosage you mentioned at 4:30

@JonasKuehneMD 3 ай бұрын

I only take a total of 5 to 6 mg per day or 10 to 12 drops, as I mentioned in the video. The doses of 0.5-4mg/kg are the upper limit for IV use. I would not recommend to take anywhere near that much.

@bh9262 3 ай бұрын

@@JonasKuehneMD I have seen the same dosage recommendation in another source and I agree. Seems like an excessive amount. I'll use a few drops to see how I respond to it and go from there.

@mariannasarracino 3 ай бұрын

I wonder if MB could be useful for cataracts.

@JonasKuehneMD 3 ай бұрын

I have not come across any research on this. I am hard-pressed to see a mechanism here unfortunately.

@abdullahalmogbel7943 Ай бұрын

I started taking MB 14 days ago, I brought it because I heard it’s good for depression, I take 20 drops daily and increased it to 30 drops. ZERO EFFECTS 😢 Should I increase my dosage more? My weight is 70KG

@JonasKuehneMD 29 күн бұрын

It’s may take a bit longer to work and also may require a slightly higher dose. This is not medical advice, of course and should be discussed with your treating physician. For my patience I do not recommend more than 30 mg daily. Also keep in mind that it may not work for all types of depression and individual people may react differently. Interestingly, a gluten-free diet may greatly benefit depressive symptoms. And I’m saying this, as someone who did not think much of gluten-free foods for a long time.