3 Things: 1. On a quick search (I haven’t looked into this deeply), taurine seems to reduce or attenuate increases in cholesterol lipoproteins according to a meta-analysis (DOI: 10.1016/j.ejphar.2020.173533). So, as I suspected, it isn’t much of a worry (I’ll need to confirm this) - yet the association with increased blood levels is still a mystery - why do you think it might be the case? Let’s take some guesses! 2. And, apparently I see 'orange' as 'red', yet I'm not color blind.. 3. @6:43 - that should read 'SASP', not 'SAPS'.

I worked in health care for 33 years. The first 13 of those years was in a seniors' nursing home. I have seen residents who lived to be well into their 90's but were wheelchair bound since they were 70. Longevity IS NOT the preferred outcome (unless you are scared to die I suppose), but rather quality of life. Living to be 85 years old while still being active, independent, mobile, mostly free of pain and living and loving those you care about is the goal. When I look at these sorts of studies, I am interested in longevity potential but I key in on those aspects that imply a better quality of life, i.e. hirer bone density from Taurine supplementation.

Maybe our lives won’t be extended to a significant degree but taurine may help improve quality of life in our later years.

Highlights 💡 Taurine supplementation increased lifespan by 10-12% in mice. 💡 Taurine supplementation reduced body fat, improved muscle strength, and blood sugar levels. 💡 Taurine showed potential in reducing senescent cells and increasing stem cells. 💡 The study suggests that taurine can be beneficial later in life, even if not taken in the earliest stages. 💡 While there are some potential negatives associated with taurine, further research is needed to fully understand its effects in humans.

Very informative video. I am a 64 year old male. I started taking a Taurine 500mg supplement about 3 months ago. I have been getting better sleep. I have also noticed more energy. My sleep is more restful and deep. My energy has slightly increased. I plan to continue to take Taurine.

well done. years ago, i found a book where a woman claimed to cure her asthma using vits a(retinol), c and e. it worked for me too. then it stopped working. but i noticed it worked after i'd eaten a tin of smoked oysters. i worked out it was the high level of taurine in oysters that was what enabled my body to make use of oil-based vitamins like retinol and vit e through the production of gall. i hope this information helps.

Taurine caused my dogs cataract to go away. It came back years later but Taurine again helped. My kitty was literally dying of heart disease. L Taurine brought him back and he lived quite some time after that.

My vet recommended it for my dying dogs heart and he lived months longer than predicted.

Ok, hear me out. I'm 41yo, reasonably healthy male. I've just started supplementing taurine and noticed some magical things started happening! Energy levels are up, very noticeably - I used to love working out but over the last few years I've somewhat deflated, lost my edge and will to work out - straight after supplementing taurine I started to feel the urge, the tingle to hit the gym and my muscles hard again! The quality of sleep dramatically improved, especially the falling asleep aspect, which in turn seems to have started to normalise my circadian rhythm. Borderline insomnia has been my struggle as long as I can remember. I've always dreamt of becoming an early bird - maybe now I have a chance to achieve it. But wait, there's more! Most importantly of all I noticed a dramatic improvement in my RSI (forearms) and radial nerve damage in my right arm. The pain has gone from severe to barely noticeable just after a couple of days of supplementing taurine. Before, I've tried everything, all supplements (apart from the taurine) and exercises, including the "nerve flossing" exercises, with very little impact. Looking forward to seeing what comes next. Best regards to all!

I am 69 yoa. I had been taking 1grm/day taurine for 5 years. The new study on taurine up to 6 grms/day is game changing for me. So, I have several decades more extension in my healthy lifespan.

Based on the content of the video, here's a summary of the key points discussed regarding the study on taurine and its potential effects on lifespan, health span, stem cells, and cellular senescence: 1. **Lifespan and Taurine Levels:** - The study measured taurine levels in blood across different biological systems, including mice, monkeys, and humans. - In humans, taurine levels decrease with age, with a significant reduction by age 50. - Mice were fed either a taurine-supplemented or non-supplemented diet. Those supplemented with taurine had a 10-12% longer lifespan compared to the non-supplemented group. - Notably, taurine supplementation began in middle age for the mice, suggesting its benefits can still be realized later in life. 2. **Metrics of Health Span:** - Taurine supplementation led to reduced body fat, improved muscle strength, and better blood sugar levels. - Bone health was positively impacted, with increased bone volume and improved bone strength observed in taurine-supplemented groups. 3. **Stem Cells and Cellular Senescence:** - Stem cells are crucial for healing and defense against pathogens, while senescent cells can negatively affect surrounding cells. - Taurine supplementation was associated with reduced cellular senescence markers in various tissues. - An experiment involving gene analysis suggested a potential increase in mitotically active stem cells due to taurine supplementation. 4. **Correlations and Interpretation:** - The study had animal models (mice) as well as data from monkeys and humans. - Positive correlations were found between taurine levels and various health markers, including reduced inflammation and obesity. - There were also negative correlations, such as dyslipidemia and elevated liver enzyme levels, that were not extensively discussed in the video. - The presenter emphasized the need to consider both positive and negative correlations and to avoid oversimplifying the results. 5. **Application and Implications:** - The presenter was cautious about the interpretation and emphasized the potential but speculative nature of the findings. - While taurine might not extend human lifespan by 12%, it could still have significant effects on overall health. - Taurine supplementation later in life could be impactful, potentially compensating for earlier lifestyle habits. - The presenter suggested watching their detailed study analysis for more comprehensive information on the findings.

I'm practically a 5 year old when it comes to these topics so I appreciate being taught this way! Thank you

Since I feel having being called out I want to clarify some things: 1) the fact that I use your videos for taking naps doesn't mean I don't follow them, when I wake up I usually start again to the last thing I remember 2) it means you have a nice calming voice 3) I also use Andrew hubermann's videos for the same purpose because he has a warm calming voice.

I'm 44 years old, and I take taurine every day. I've been working in shifts for 18 years. Taurine is a salvation for my sleep, and as I train every day, strength and cardio it helps a lot to endure shifts, sleeping during the day and daily physical exercise.

One of the biggest problems with mouse studies, apart from the obviously massive gap in genetic makeup, is that their standard laboratory diet is extremely poor and unnatural. They are fed primarily corn and soy, both usually GMO. So basically any change in diet, or supplementation, may show an improvement where a more natural baseline diet would not. We just don’t know. That’s also how fad diets get started in human populations: the standard American diet is so poor in nutrients and rich in pollutants that almost any change will yield improvements.

I’ve read it helps with tinnitus. A lot of people would love to hear you address that.

Been taking it for 2 weeks and 3 days and on the 4th day I finally can feel the difference and I love it and feel great!

I'm nearing 70. As diabetic from the past (eight years on insulin after a heart attack), fasting one day a week (for 36-40 hours) led to improvement in A1C. Having been encouraged by this, I went aggressively for HFLC diet and overnight fasting (found out I 'm good at it!) with 7,000 steps everyday (sometimes within the house because of inclement weather) for over 7 months. However, I noticed I wasn't producing enough energy to go up a hill and my LdL and total cholesterol had gone up (and LdL above the range for the first time). The triglycerides remained below 80. A1C was 5.4. I had lost over 35 pounds and reached a BMI of 19.5 which worried my doctor. So I went for a week-long program (over the net) run by a famous doctor (doing research first using Atkins then Keto for over 25 years) but they were unable or unwilling to talk about how to address "low power". The course was mainly for people who had high BMI. I then went for an exercise bike after getting fooled by studies on "Italian alpine cyclists". Now after another 15 months, this June (2023), after 22 months being out of any medication for diabetes but still with "low power", I found you. You made me realize the folly of many things including "insulin resistance" for those who have no weight to lose. I had already played with relaxing the A1C to a steady state of 6.5 but now with LdL and total cholesterol both within range. I had also realized since the beginning of 2023, that one thing is autophagy but another thing is to have cell death. Lactic acid production from that "cyclist trainer" made cell death possibly worse. So I am increasingly saying: "it's the health of the mitochondria stupid". It's clear for me it’s less calorie, be it from carb or fat (that's from you - thank you), and with supplementation to reduce ROS. The Taurine study, as many of these studies go, is mainly for overweight people and those with blood sugar issues.

I love that our generation is pretty much the test subjects for thousands of supplements

Thank you! This just showed up in my KZfaq feed, and I'm so glad it did! I've been interested in and learning as much as I can about science, especially regarding health, my entire life. My education and training has not been in the science or medical field, it's one of my favorite interests. I love learning as much as I am able, it's a passion of mine. So, Geek on! The information you share will help so many people... including people who are so inclined, as I am, are able to Geek Out with you ❤ Thank you!

Thank you for being truthful and nuanced while still keeping it fun, I wish we had more content creator like you, cheers

First time; YT sent me. I like your style and information and delivery. You’re a very I’d say innately talented, and solid teacher, your explanations are key to my staying power. And for me? I need things explained, as to why I’d do this or that, and not just the hyper excitement of new findings, but also the restraint of a physician with years of experience behind him. I got that from you. And you’re too young, lol. So thanks! Subbed and all thumbs up. 👍👍😊

I take 2 grams first thing in water every day, I am 74 years old and think the benefits outweigh the negatives I weight train twice a week pushing hard increasing weight or reps every workout, this I find is all good, I add creatine every day also.

Great video on the topic and a really fine example of how to critically think about scientific papers beyond the headlines.

I super appreciate when intelligent content is put together for all of us to consume. Just found you, now time to watch all your content! Thank you!!

I like this guy he is well presented and offers up the study rather then just take my word for as most do.

You do a great job of explaining challenging concepts and you do it with charm and humor.

Your channel is fast becoming one of my favorites! Thank you for the balanced way that you presented the information from the study.

Important to note that there are plenty of ways to get taurine. Diets high in meats and fish will probably have all the taurine you would need. As far as im aware, seafoods are the most abundant sources of taurine naturally. This could be one reason people in southeast Asia have such long lifespans. Plenty of taurine found naturally in their diets.

Looking forward to the second segment on Taurine supplementation.

Wow! I am impressed! Excellent video, professionally done, well explained, etc., etc. Thank you so much for taking your valuable time to share this with us!

Thank you for a totally unbiased evaluation this is very refreshing, as a type 2 diabetic i think i will sit on the fence for now loved the video.

As always, very unbiased clear and honest explanation! Thanks! And thumb up 👍

Fantastic! Thanks for the detail, at 52yo I’m learning new things everyday on my health and wellness journey. I’m subscribing and look forward to geeking out with you on your other videos! Thanks for posting! 🤗

You deserve a larger audience! Your presentation is way better than than I have come to expect!✅ I'll be frequent visitor. Thanks.

Thank you so much for the quality of the information! Really appreciate it.

I like Red Bull. (I know it's not healthy). This led me to taurine about 5 years ago. I have arthritis in the neck which causes bad cramps and spasms. Once or twice a week I take a quarter teaspoon of taurine, fixes the problem 100%. 😎👍

Wow! Your analysis of the the data, pro and con, was spot on. Sadly, this type analysis is exceedingly rare

Great video. I like how you're touching on all the potential aspects. Subscribed.

Thank you for hearing, listening to the CAll. Glad you're in the number and sharing the space at this moment in time. I love you

Another awesome video! I look forward to watching your other videos on this fascinating topic!

Great vid! Please do one on Telomers and the anti aging process. This + DNA editing will and proper supplement nutrition and exercise will def. Increase lifespan

Love your presentation. You have a great communication style. Thank you!

This is awesome I have been taking tarine for 15 years I had a nature path to a neurotransmitter test on me and said my body was not making it and I needed to take it and it was huge cuz I suddenly calmed down Good to know that it will do all this other stuff too thanks!

Boron and magnesium changed my life. They cured my back pain. I take them everyday. I have had zero side effects. My back was really bad. Now I'm pain free.

Great stuff physionic. Keep up the great work 👍

I’ve subscribed. Your attention to detail but cautious optimism is exactly what I’m here for. I experienced quite an unexpected potential benefit: I suffered 11 months of slight double vision in which my left eye would not come quite back to center when looking to my left and back. Just three weeks after taking two big taurine pills daily, it virtually stopped. No one can say whether it was taurine but I can’t help but make a possible connection. Thanks

Kudos for an exceptionally clear, well balanced presentation. I rarely watch health related programs, as so many make hyperbolic, unsubstantiated claims. The title "Nutrient of Youth" suggested this video would fit that stereotype. I would not have bothered watching except for wondering what Taurine is. Your source citation being the prestigious publication 'Science', immediately dispelled concern about baseless assertions.

Subscribed! I'm 66 and have studied health and fitness on a daily basis for the past 30 years, learning something new on nearly a daily basis. I salute your clearly articulated narration and presentation. There are so many presenters out there that just do not speak clearly, nor present info in a logical manner. My daily supplement regimen has included taurine for over 20 years. When you hit 60, you body and mind will become more sensitive to finding the optimal nutritional balance point, aka homeostasis. I'm interested now in watching all of your presentations, and curious to know your thoughts on N-acytl-L Carnosine (which I also take).

I like your way of explaining things. Very nice video. Keep it up, Nick 👍

Great video. Glad this showed up in my recommendations.

Impressive interpretation and presentation. No hype, just facts. Subscribed.

Your teaching style is informative and keeps one engaged 👍😎

You have the gift of balanced research synthesizing thoughts and teaching. A++!

As always, very informative, thank you!

Nice job, the thing with a scientific study is that it is one study. The thing that makes good science is repeatability and if results stand the test of time.

Really good presentation. I have had some questions and concerns about the level of Taurine to continue at this later stage of life.

Thank you so much fir all the info you share.

Many thanks Nic for a very informative video. I am 65 and started taking Taurine a few months ago.

Taurine has been on my mind for the last few years and I'm so happy to have found this video (and channel!) that expounds greatly upon my interest. I'm currently using a health drink that focus' on taurine supplementation. Personally, I do have reservations per liver issues.

I've considered taurine but was sure about it. You gave me the clarity needed. 👍👍👍

an excellent description, thank you

You are the real deal! Love it! Subscribed!!

@Physionic -- -- I only discovered your channel today -- and I wanted to say 2 things: 1) I am gald SOMEONE finally decided to dedicate TIME & ENERGY to explaining Health Studies. (Why? because most of the time pharmaceutical companies finance these studies -- and many of them NEVER get seen or heard about via Main Stream channels. I agree 100% with your tag line -- "Learn your body", because when we learn HOW TO READ THE "SIGNS" -- then we also know what to add or subtract from the system. These studies --- give you the "inside baseball" of what is really going on, so THANK you for making the time to explain these studies. 2) Did anyone ever tell you that -- you look like "Simon Sinek"?? (IF you don't know who he is -- look him up )

I'd like to hear more about the bone growth aspect. Could this help with osteopenia, joint rehabilitation, dental health?

Excellent walkthrough! Thanks!

Thank you for the video. Your English is perfect and very proper. I am gonna look up the word brevity and intact in my dictionary. Thank you smart guy!

I added torine to my supplement stack. I take 2h in the morning and 2 gram in the afternoon. I also added glycine 5g after every meal. What I have read I think has similar positive affect. It reduces blood glucose, it reduces inflammation etc but it works on other aspects in the body.

🥴 I feel younger just hearing about this ... Amazing !!

I appreciate your content and find your delivery is both informative and entertaining. I have subscribed and ordered an inexpensive taurine supplement on Amazon. Thank you.

Experienced a Main Coon cat of poor health; he lived 16 years although the Veterinarian had said early on, he should have already passed (Heart) shortly after his birth. The Veterinarian (U. of F.) did recommend Taurine be included in his specialized cat food. This Video went beyond my cat’s Docter’s explanation, and Buddy (Maine Coone) outlived his health disposition by more than doubling his years. Although his health rapidly declined and was put to sleep early in his last year. However, he and I enjoyed his added time. Now it is nearing my time, late but am going to start taking this additive (Taurine).

I offer you my sincerest gratitude. You have given the common observer a great deal of positive affect information the contemplate. If a individual who views this information as a positive inflow and combines it strongly with the mysterious placebo affect, the ability for that individual to start a taurine regiment and meditate on the positive effects on the body, lifespan, overall, I can most definitely see even a 15 to 20 percent lifespan increase. But hey, don't take my word for it, the tools of research and analytical data will provide the seeker with more than sufficient information. You sir, have a new subscriber. Again, thank you.

Why do our bodies produce less Taurine as we age? What processes are we trying to compensate for? Does simply adding more to our bodies actually fix the underlying problem?

I am finding taurine helps with improvement in Gallbladder and Liver health. Increased bile production, and parasite removal. Taurine is a supplement I include as part of a way of life, and do not depend on it solely, or treat it like a medication. It works synergistically, and in my experience is best used from that point of view.

as always a mind-blowing segment. Thanks a mil. .

Excellent info. Thank you for a great video

NERD ON!!! Thanks for the balancing nuances.

I added 1-2g taurine to my afternoon stack about 5yrs ago. It’s no magic bullet, but is beneficial along with other aminos.

Amazing delivery!!

Anther great dissection of data related to the subject of how the body responds to a myriad of variables. I appreciate the work you put into sorting and analyzing this data. No wonder it takes so much time, money and effort to research, produce, test and obtain a "reasonable validation" for any type of drug (the beneficial type, that is). Specially when you considering that there aren't any "legal" human testing to start with and we have to rely on animal anatomy to produce any kind of scientific "POC". Thanks again for sharing. Cheers!

Good breakdown

I volunteer for the study , my idea for a study, where a catalyst, like Quercetin or French pine-bark extract is used to increase the effectiveness of Taurine.

Thanks! I really like when u simplified the data for us guys with a 3rd grade education , continue the good work 😊

I really like your analysis. You seem to look at all sides of the issue

would be cool if you made a video about bone density in general

After 2 minutes of listening, I gotta say you don't need to worry about prolonging your life man, you'll outlive us all.

I just found you on my phone! Thank You for bringing this information to ALL of us! And everyone behind the scenes T00 make this possible! ⚡💞⚡

Your videos are presented well and informative. Thanks!

Ill be happy to supply you a new sound effect file for the current cell division sound effects… that aside, extremely interesting clip as I have added taurine as of recent into my ‘shot glass’ of health and longevity… now off to find your next video - THANKS N!!!

Would love to hear your thoughts on the research of L-arginine and it’s effects on nitric oxide. Should we be supplementing with it for better athletic performance or as we age when our nitric oxide declines?

Excellent overview - thanks.

Listening second time around. Very informative.

What I found with 1000mg of taurine/day was after one week 1. Libido was increased. 2. Night vision was decreased. 3. After one week the night vision component is still reduced but less than at first unless two doses are taken. During my morning walk before daybreak I look down the path to the end where a grey bench sits. Before taurine I could see this bench and surrounding trees. Now I must be half way down the path to even see the bench but it is slightly less visible at 1/4 mile in the dark depending upon lunar state. Night vision is important to me.

Excellent and fascinating presentation!

I remember similar life extensions for mice fed with GLYNAC, would love to see mice on GLYNAC and Taurine together.

Simply the best content on physiology

Your very smart. Thank you for sharing your knowledge. Subscribed

Good job fella…keep’em coming.

for me taurine boosted vo2max. Easier to train from the very first try. I'm afraid a lot of suplements has its own + and - . Its interesing for sure

I read years ago that taurine was recommended for vegans so I've been on 1,000 mg per day for years. I have a genetic disorder called PCOS which, among other things, increases my risk of diabetes, despite my super healthy lifestyle and normal weight. My latest blood tests are in the pre-diabetes range. Very discouraging. As a now-70-year-old, I will continue my healthy no-sugar diet and exercise, as well as the taurine. Thanks for this video!