The use of Mobile Phase pH as a Method Development Tool
Пікірлер: 42
@prasannakumar16149 ай бұрын
Only the master can make tough concepts to very understandable way... u r my master, bhaskar sir
@rahulkulkarni30372 жыл бұрын
Beautifully explained importants of pka vs pH and their retention in RP-HPLC thank you Sir
@bhawanibanerjee12144 ай бұрын
Thank you for this, very helpful for method development. Cheers!
@syedrashedfaizan59902 жыл бұрын
Simply and easy explanation, thank you for sharing such awesome content.
@raju8184 Жыл бұрын
Excellent explanation, keep doing good work
@rajujonnada8987 Жыл бұрын
nice information...its useful to pharma analysts
@riyazdantroliya3711 Жыл бұрын
Valuable knowledge , thanks sir
@siddhachavan8604 Жыл бұрын
Nice and simplest explain
@bestdancevideos22532 жыл бұрын
Superb Superb Superb Superb Superb Sir
@jaykumarbhatt8841 Жыл бұрын
Very nice 👌
@buddepumohanarao83092 жыл бұрын
Sir please make video on HPLC column selecting
@venkateshsanthanam1002 жыл бұрын
Thanks sir Nice explained sir
@seyedmohammadseyedkhademi24542 жыл бұрын
Very good please go on about troubleshooting of HPLC
@sanavadapankaj182 жыл бұрын
Good Sir & Thank u ...
@thehealer83302 жыл бұрын
If sample contain more than 1 analyte I.e 2 or 3. How pka value and pH Mobil phase calculate??
@Learnwithsimon272 жыл бұрын
Really good content.
@anantdhopat99282 жыл бұрын
Excellent sir,make more videos on usp general chapters
@sachintadge81242 жыл бұрын
Right...please make video sir
@sachintadge81242 жыл бұрын
Nice sir..
@prasannakumar16149 ай бұрын
Sir, if our compound having acidic and basic both, then how will manage the mobile phase pH.. please reply
@user-yi7kj8ih8f Жыл бұрын
Thank you sir
@nguyenhoaiphu5 ай бұрын
Could you tell me the app you use to draff, sir?
@azhar17kkk2 жыл бұрын
Thanks Sir, it will be just opposite in normal phase column right? Please correct me if I'm wrong.
@thanishasayyad28452 жыл бұрын
But, acidic compounds retained in acidic pH and basic compounds retained in basic pH.
@prasannakumar16149 ай бұрын
Yes, that's not correct. At acidic pH, basic compounds tend to undergo ionization, releasing ions and becoming more soluble in water. The specific behavior can depend on the nature of the compound and the pH conditions.
@atozfacts94032 жыл бұрын
What a wonderful presentation it is, which I have never been gone through. how do we know the pka of new compound?
@pharmagrowthhub30832 жыл бұрын
Thank u for your comment. watch my video for pka measurement.
@lellanarendrakumar68312 жыл бұрын
Thank you❤
@sunandasolomon6406 Жыл бұрын
PKa of my compound is 7.6. What should be the pH of my mobile phaase?
@bestdancevideos22532 жыл бұрын
I Want column chemistry
@mayurib51862 жыл бұрын
Compound remains in which state while retaining on column? Also plz make a vedio on behaviour of zwitterion in chromatography. How does it behave?
@vinodsingh7002 жыл бұрын
Sir what about neutal molecules?
@sanavadapankaj182 жыл бұрын
Neutral molecule not affect ed by ph change
@parmardevendra4056 Жыл бұрын
Sir, if both drug pka I'd 8.71 & 12.49 so, how can I select mobile phase.
@sanavadapankaj182 жыл бұрын
If pka is 17 , what should I have to do.
@bestdancevideos22532 жыл бұрын
Why not Upload new Videos Sir
@tadalavenkateswararao20902 жыл бұрын
Sir how to know compound acidc or base
@apnacoffeebreak74272 жыл бұрын
Sir, what impact will be there on LC if Mobile phase's pka and Compound's Pka is same.?
@TheChamp91100 Жыл бұрын
PEAK BROADENING
@elumalaitamil3230 Жыл бұрын
Dear sir, I have one doubt in analytical method validation. When the monograph method is used for validation in compound having more impurities and some of impurity (two or three) elutes same RT how to arrive RRF in this case further monograph mentioned RRF is 1. Please suggest the way forward 🙏