The Aging but Resilient Brain: Keeping Neurons Happy

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University of California Television (UCTV)

Күн бұрын

(Visit: www.uctv.tv/) Joel Kramer, UCSF Professor of Neuropsychology and the Director of the Memory and Aging Center Neuropsychology program. He explores the underlying biological mechanisms of cognitive aging, and interventions that may optimize cognitive functioning as we age. Recorded on 11/17/2011. [4/2012] [Show ID: 23205]
Emotions, Thoughts and Health: What All Aging Bodies Should Know -- Mini Medical School for the Public Presented by UCSF Osher Center for Integrative Medicine
(www.uctv.tv/series/676)
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Пікірлер: 162

@zhinan888 2 жыл бұрын

My grandma from mother's side lived till 99 (and grandma from father's side lived till 96) and her mind was clear and sharp till the very end. She always had a positive look on life and nothing ever got to her. She smoked 2 pack a day. 😀

@marileneduarte9000 2 жыл бұрын

Some people make a difference in the world!!!! I am very grateful to YOU ....Brilliant Doctor

@hascleavrahmbenyoseph7186 2 жыл бұрын

I started walking more in the last few months and I thought I had noticed a slight improvement in my memory. This video confirms that I may be right about memory improvement. Thanks Proff. Kramer for this educational video. 👍👍

@derekturnswood 2 жыл бұрын

It would be nice to see an update of this 10 year old presentation to get the latest research

@squaretriangle9208 2 жыл бұрын

good stuff! the internet brought about some very good things - listening to a presentation that was done a decade ago on another continent (I´m from Europe) in the pandemic. is simply wonderful!!

@howellwong11 2 жыл бұрын

I'm 89 years old and my cognitive ability is still intact, but retaining my short term memory is the problem.

@larainehruby1376 2 жыл бұрын

I’m 78 and have noticed this since age 77. Still haven’t discovered why this memory loss happens and if it is good or bad. We are beings that exist in the past, present, and future through memory, cognition and planning and imagining outcomes.

@howellwong11 2 жыл бұрын

@@larainehruby1376 I think that shot term memory loss is normal, but I also hear that it is a sign of dementia. I guess that we all will experience dementia. It is just the matter of how bad it is. I hope that my dementia is mild.

@AP-nx6xo 2 жыл бұрын

Hello… my dad takes B12 1200mcg a day sublingually. He’s 90 and sharp as a whip. All the best 👍🏻

@howellwong11 2 жыл бұрын

@@AP-nx6xo He has good genes. Most needs help, some don't.

@benildaarcilla9411 3 жыл бұрын

The presentation is gentle and happy. Very understandable even to person like me 77 yrs old and no medical background. Honestly though I have to listen and watch closely again. Very interesting. Thank you.

@tammysims8716 2 жыл бұрын

Benilda... thanks, encouraging and helpful comment.

@alysononoahu8702 2 жыл бұрын

Me 2 but it's fascinating

@naftalibendavid 2 жыл бұрын

1:02. Genes. Exercise. Think. Socialize. Sleep. Minimize inflammation. That is about it.

@conradmish7875 8 жыл бұрын

Thank you. I am 60 years young and am trying to preserve my memory and brain function. I know the brain is bio-electric and runs on circuits and connections. I sleep with an earthing sheet which improves my sleep, but the bladder is what is awakening me. I am a firm believer that the body should be connected to the earth to keep a flow of negative charge flowing. It reduces inflammation. I love studying cell signalling so your lecture has been very informative and exciting. conrad

@velvetpaws999 2 жыл бұрын

Conrad, if your bladder makes you go at night, try to drink less before going to bed, lol. As for me, I have a water bottle in my bed, and sometimes, I wake up half, drink a sip and resume sleeping. I go once every night, I get up, pee, then back to bed and 10 seconds later, I am back to being sound asleep! It's really all a matter of mind over body!

@ytcarol 2 жыл бұрын

Yes, drinking during the day is essential!

@John-ys7zz 2 жыл бұрын

Helps me to stop drinking anything after 6 PM.

@jrhunter007 2 жыл бұрын

What evidence do you have that the body "should be connected to the earth" or that it reduces inflammation, and how do you explain that? It sounds like a notion to me, and not based on fact.

@bryanjackson8917 2 жыл бұрын

That's funny, because I am firm believer in just the opposite. That is, that the body should be disconnected from the earth as much as possible (e.g., insulated by wearing shoes with rubber soles, sleeping on rubber sheets, etc.) so that our energy is not drained away.

@steshaw3 4 жыл бұрын

Only glucose? "The brain is dependent on glucose as a primary energy substrate, but is capable of utilizing ketones such as β-hydroxybutyrate (βHB) and acetoacetate (AcAc)"

@reinamacaren-a4132 3 жыл бұрын

🤯😲😱😨🤔 I'm a lil 9vet 9min in. We he said the brain only takes in glucose, I ran straight to the comments. Dr Eric Berg, KZfaq Keto Guru, would have a massive keto attack if he was in the audience 😂 I think I'm going to hold off on watching the remainder of this video🤯

@sleepsmartsmashstress8705 2 жыл бұрын

My brain is capable of utilizing ethanol to run

@joereidy5732 2 жыл бұрын

@@sleepsmartsmashstress8705 You must be a millenial

@sleepsmartsmashstress8705 2 жыл бұрын

@@joereidy5732 65 but feel 25 U R right

@joereidy5732 2 жыл бұрын

@@sleepsmartsmashstress8705 Congratulations just be glad you don't think like a 25 year old. 🙂

@donalee1975 2 жыл бұрын

Excellent study topic for me. Plus learning how cognitive behavior therapy has been beneficial for me. I am a sedentary 75 year female with many of the Constraints to my memory, yet still functioning. Happy to know reading puzzles and lifelong learning on my own has been my habit. Thank you so much for the delivery of Dr Joel Kramer, whose charts and comedy were very pleasant for the listener. Dona, CALGARY, 🇨🇦

@harshvardhanjajoo1187 10 жыл бұрын

Prof Joel, This is a fantastic crisp delivery. Thank you for enriching. Harsh

@tads5935 2 жыл бұрын

Wonderful I am 69 years old and I realized that I am beginning to have symptoms of all timers so i welcome all study's teachings, and info thank you very much I hope I could start a hold steady program good work

@TheGypsyJewess 9 жыл бұрын

love the presentation, well done. Thanks Prof Kramer.

@TheVtecpwrd 2 жыл бұрын

Great presentation . I learned a lot and enjoyed the ease of his presentation . I am grateful, and a big Thank you for teaching us.

@johnhoover2569 10 жыл бұрын

Excellent communicator.... Loved the message and the summary..... Learned a lot... and recommend this video to everyone over the age of 30.....

@user-mt8sc1dp3c 2 жыл бұрын

30년 나 며느리일때 너 며느리일때.. 엊그제 평안함을 느꼈다. 평안..감사합니다

@onedirectionlover08 Жыл бұрын

Thank you very UCTV, for such a great service, really appreciated.

@RiDankulous 7 жыл бұрын

I watched this multiple times. Thanks! It is very helpful for someone laying down good health habits in the middle age (or any age). This is motivation to do the right thing to reduce potential for serious and costly medical issues in the future.

@rosequartz4705 2 жыл бұрын

Jjjjjjjup

@mandyhamilton8083 9 жыл бұрын

Awesome video; truly amazing. Thanks a bunch :-)

@meandcadasil7093 Жыл бұрын

I have CADASIL. Simply fantastic video, nicely structured, explained in an easy to understand style, beautifully presented in a very engaging manner. Congratulations to the whole team involved in putting this together.

@anonymousAJ 2 жыл бұрын

37:30 "If you take a sample of individuals who've died and gone on on to autopsy, you'll find that a large percentage, 15, 20 percent of people who were perfectly normal at the time of their death have under the microscope the changes that we associated with Alzheimer's disease." How strong is this as evidence against the theory that beta-amyloid plaques cause Alzheimer's? Could these plaques be one symptom of Alzheimer's rather than the cause?

@MarcellaSmithVegan 10 жыл бұрын

Really enjoyed, thank you!

@Psalm146-2 2 жыл бұрын

I can tell that when I consume too much sugar I get more forgetful. And I’ve noticed that when I cut back sugar sharply it takes me two weeks + to get back to my “normal.”

@aremedyproject9569 7 жыл бұрын

He seemed embarrassed about the statin question and right then a chunk of the talk was edited out. I feel bad for doctors and scientists today because funding is so attached to the Pharma industry. If you know how to look, there is plenty of good science out there. Research journals from all over the world are accessible to everybody now. Still, one should note who's behind the journals. Learn about study design, possible motives for doing a study, and the arguments for and against in vivo vs in vitro studies (for example). We're certainly more empowered as consumers than we used to be. Cheers! ✌️😎🇨🇦

@lt9316 4 жыл бұрын

Statins are killers. A quick research of public comment sharing horror stories is done by going to Amazon books, search Dangers of Statins, and then read the comments.... another proof is observing friends, family, neighbors, and the steady decline of health ( w bigger bags of meds from the pharmacy/ more specialists) they require because of "aging." Doctors should be ashamed. Get off processed food, statins, corn oil, corn syrup, use coconut oil for starters! FDA food pyramid belongs in trash w statins....

@AlexM-jd2ro 2 жыл бұрын

Yeah...but what can we do? My doctor almost killed me on the operating table for an elective surgery, and insurance still paid him a lot of money...they push statins and metformin while simple barberine can take care of both issues...poor mankind...we deserve covid...

@KEEBLERVET 9 жыл бұрын

Fascinating ... Shared on Google and recommended

@solomit1 2 жыл бұрын

Meditation keeps the mind young fresh observing yourself everyday renews the mind so does not accumulate memories live in present moment not the past.

@Ullbritt 12 жыл бұрын

thx a lot, i love UCtelevision

@shellyjose1967 2 жыл бұрын

Great Presentation....

@iwnunn7999 8 жыл бұрын

You misunderstood. I was amazed that someone in the audience didn't know what rem sleep was

@carleenmejzastrumunderthes4130 2 жыл бұрын

Excellent!

@farnooshsadeghi3673 2 жыл бұрын

While wisdom is increasing with age, is it wise to say we are getting older even in brain cells? Or is it due to psychologically becoming more vulnerable?

@buffsol1969 11 жыл бұрын

VERY GOOD,I SUGGEST THAT EVERYONE SHOULD SEE THIS..

@ESTELLE1139 3 жыл бұрын

My guess is that curcumin and fish oil would be healthier than NSAIDS for anti-inflamatories to help cognitive health.

@bernadettekennedy2981 5 жыл бұрын

Look up Dr. Bradshaw and tea. Very good for memory and the brain.

@AP-nx6xo 2 жыл бұрын

I’m 60 years young woman ..I look 40 so I’m told lol. My secret is : light weight training , melatonin for sleep, B12 1200 mcg sublingually ( my legs were going numb…. Memory was getting bad.. I was very concerned). Blood work showed deficiency) codliver oil, omega 3s, no sugar, ketogenic diet with healthy fats ( olive oil, MCT Oil( energy and cognition) coconut oil) salt, lutein to prevent macular degeneration which my dad has, vitamin D. It’s easy to live this way because it pays off . All the best to every one !

@eddiemartin85 2 жыл бұрын

Great

@Darienbeagle 12 жыл бұрын

Excellent! A great speaker, fascinating talk.

@pushkalapalanivelu9507 2 жыл бұрын

Very interesting.Very simple e xplanation about brain with aging. Ofcourse its very useful for aged ones likee

@martinirving3824 5 жыл бұрын

"Central obesity" associated with the highest risk for dementia? You might as well say "insulin resistance" is associated with the highest risk for dementia. Subcutaneous fat is actually protective.

@vincentanguoni8938 3 жыл бұрын

This is 6 years old..

@erzsebetnilsson580 2 жыл бұрын

Loved to acknowledge your information. LOVE BOTH THE NUTRITIANCE and THE DOCTORS and THE OLD PEOPLES treatment for various illness.

@thomaslucas867 3 жыл бұрын

When I was in training fifty years ago, it seemed in psychiatry the main people presented with memory loss, was wernicke's syndrome secondary to alcohol abuse. Alzheimers was not mentioned at that time. We did have loder people then! We may have envirmental factors that impact the epidemology of alzheimer's. Could the pathologic and chemical changes be secondary to physical exposures?.

@joanheaney4103 4 жыл бұрын

Great presentation......learned alot!

@joereidy5732 2 жыл бұрын

Please tell me what you learned ....just three things so I don't have to watch this borefest. Thanks

@janeyd5280 2 жыл бұрын

@Joe Reidy agree 👍 I can't take it all in.!

@joereidy5732 2 жыл бұрын

@@janeyd5280 Dang we need someone with some patience ...LOL

@velvetpaws999 2 жыл бұрын

That memory test would work or not work for me, depending on how one sees it: If I wanted to memorize it, because it is important, or just for game, as a challenge, I would. If I feel that it has no relevance, I would discard it and never think of it again. Other than that, I have found that my memory is improving: I can now remember all my credit card numbers, I can read entire lines of information and remember them exactly, like phone numbers or paragraphs of text. So no aging here, it seems to me. In April, I will have lived 36,792,000 minutes. You can figure this one out!

@deb0740 11 жыл бұрын

very good video, i will be recommending it.

@Nic7320 11 жыл бұрын

Slide at 11:40 should read time, not processing speed, to show a slowing relationship as we age.

@diannefitzmaurice9813 4 жыл бұрын

Good presentation but sound quality is very poor .

@NyanKitty01Kawaii 11 жыл бұрын

This was a interesting study. I'm GlaD to know this now at an early age because complications in memory seem to run on my moms side, it's kind of scary. Hopefully I can help my mom out and improve my cognition to avoid this.

@johngilmour8945 2 жыл бұрын

It Matters Not What Age You Are, You can Still Place Important Information into Your Long Term Memory Archives, HOW? by reading the subject matter, ''FOUR PAGES PER NIGHT JUST BEFORE SLEEP"" this is a THEORY I developed and Validated to myself over my lifetime! Respectfully zYours, John Gilmour Toronto Canada!

@JoeEPena 2 жыл бұрын

Looks like you are at the freeze line, hope you warm up!!

@Joebethere7 2 жыл бұрын

Is neural inflammation caused by trauma? If not, what causes it? Explaining this would be helpful

@AdventureAwaits972 5 жыл бұрын

I am very surprised that supplements like vitamin D3 and Omega 3 in the form of DHA + EPA were treated as trivial in this talk. Both have been studied for decades. There has been very clear compelling research showing the correlation between Alzheimer's disease (AD) and people with inadequate amounts. I am puzzled.

@twentyfourinvest 5 жыл бұрын

Because pharma owns this lecture.

@Katmandu29 2 жыл бұрын

Good answer! Big pharma yep.

@robman2095 2 жыл бұрын

Made 9 years ago. Maybe progress has been made in this area since then.

@ericfrey2866 Жыл бұрын

You are 100% correct. This is why this msn is never someone I would go see as a world class practitioner of medicine. He is a theoretician

@ericfrey2866 Жыл бұрын

Yes pharma schill

@anonymousAJ 2 жыл бұрын

9:00 "The brain will only take glucose" Does this mean the brain cannot utilize ketones?

@nydiahernandez6072 9 жыл бұрын

Preparing for the unknown has been underneath experience and a great help to my gold keep up the good work youtube

@oldsachem 2 жыл бұрын

How does Covid affect protein accumulation in the brain? Does anyone know?

@lt9316 4 жыл бұрын

At 57:35? What was the comment made from the man in the audience?

@oldsachem 2 жыл бұрын

Dendrite is misspelled at 44:06.

@mscorrell 2 жыл бұрын

I've had a stroke, which has given me a greater appreciation of The Simpsons.

@edwardwalsh4454 2 жыл бұрын

12:12 #32 answer is ? E my guess as one element is moved in each frame!

@edwardwalsh4454 2 жыл бұрын

Sorry is it B as I noticed my mistake

@adamsblanchard836 Жыл бұрын

How many people say they don't remember as well as they used to and are speaking about the same memories forming 35 years ago and just be too ignorant to recognize like not recognizing idgaf that "and just "be" to ignorant" isn't a proper grammatical illustration of the English language in someone else's opinion.

@dhananjayjoshi2206 2 жыл бұрын

Novel problem solving @12:36 is it E?

@martinirving3824 5 жыл бұрын

2012 this was uploaded? Nonetheless, an expert such as this should've been well aware that a lot of the brain can run on ketones and ever prefers them. And maybe he did know that but was reluctant to say it? Still, it's interesting to see how old paradigms are maintained with concrete rigidity well into a time we should simply know better and accept" new" (old, ignored) science.

@anonymousAJ 2 жыл бұрын

19:50 "What happens in Alzheimer's disease is that these proteins are being cut at the wrong spot, and because of the way in which these proteins are becoming misshapen, they start to glom together, and once they start to glom together, they form these plaques, and whether it's the free-floating abnormal proteins or it's the collection of these abnormal proteins is not altogether clear, but there's no doubt that beta-amyloid is playing a role." Is it impossible to have Alzheimer's without these plaques?

@graceyow7159 2 жыл бұрын

Just facts about general condition of maybe average individuals. No mention of health condition, lifestyle. I make this comment bec I have read of centenarians who have greater mental faculties than most. They commonly good health and joyfulness about life. Chronological age need not be a trap for biological age.

@LeslieDaCostaJr 2 жыл бұрын

54:02 Cognitive exercises

@mylucidlife495 5 жыл бұрын

"At some point evolution figured out..." good job, evolution! 😂

@ivanahumpalot4489 2 жыл бұрын

How do I prevent Brain farts???

@psiclops521 5 жыл бұрын

Inre cognitive exercise, if your work is intellectual and you spend 40 hours a week doing challenging mental work, does that count as cognitive exercise? In addition, does listening to many hours of science lectures on KZfaq count?

@vincentanguoni8938 3 жыл бұрын

Da!!! Lucky you!

@nguoithichhoasim1233 2 жыл бұрын

In read in an article , the author advices you read and WRITE DOWN what we like , not typing , This will help memory too . And also learning a new language .

@nixodian 3 жыл бұрын

9min11 , brain only take glucose? from what Jason Fung, Dr Berg, and new science says that ketones are the prefered fuel of the brain, not glucose

@janicemims9799 4 жыл бұрын

What about ketones?

@claudio9788 11 жыл бұрын

sub it in spanish please. thanks!

@casiandsouza7031 5 жыл бұрын

My personal experience is that waking frequently should be used to get up and facilitate circulation. I sleep better later.

@juliaisabella3000 5 жыл бұрын

I'm just trying to understand how this is true regarding the brains use of glucose when I have seen videos of people with Alzheimer's who began eating a keto diet primarily coconut oil and had a drastic reduction in symptoms due to the brains use of lipids instead of glucose

@ClarkAve321 9 жыл бұрын

@25:25 Someone please give me a thumbs up when you realize... haha

@ceecee6679 2 жыл бұрын

opening music is gonna make me h9mocidal

@thefallenone7988 2 жыл бұрын

I heard grass unwires the brain

@coastaltoaster1371 6 жыл бұрын

@9:00 9min in, needs a edit. Not the whole video just the part about energy consumption. - The brain runs on BetaHydroxyButarate Keytones and glucose. The brain is not solely consuming glucose.

@mscorrell 2 жыл бұрын

Only glucose; no ketones?

@kevin.afton_ 2 жыл бұрын

Cant burn lipids? So how did the eskimos stay alive?

@theguardianaj 11 жыл бұрын

Seriously? You interrupted a lecture to ask what REM sleep is!?

@CC-kl4nh 2 ай бұрын

Oh great…,

@iwnunn7999 8 жыл бұрын

"What is rem sleep?" Who is this audience? No offense to the guy asking the question.

@margaritaorlova6697 8 жыл бұрын

+IW Nunn, I have googled for you {rem sleep} = "Rapid eye movement sleep (REM sleep, REMS) is a unique phase of mammalian sleep characterized by random movement of the eyes, low muscle tone throughout the body, and the propensity of the sleeper to dream vividly."

@anthonyjerome2297 8 жыл бұрын

I asked myself the same question. This seems like an advance class. It's unlikely for someone to not know.

@sarahtelfer6051 2 жыл бұрын

Very informative but you have a tendency to “uptalk” where your voice goes up at the end of your sentences:)

@juliensorel1427 2 жыл бұрын

Isn't this old info?

@wonderwagon3304 2 жыл бұрын

The lecture is 10 years old.

@martinirving3824 5 жыл бұрын

Lack of sleep contributes to insulin resistance.

@traceler 8 жыл бұрын

How can he say brain only takes glucose and can't burn lipids or fats ( 9.11)? that is not correct, brain goes very well in ketones

@someonelse48 8 жыл бұрын

+traceler the body can convert amino acids into glucose... so you don't really need any carbs

@Vunderbread 8 жыл бұрын

+Tom Schultz of course you do. the body can only handle a small amount of oils, fats, and protein. Getting any more than 40% of calories from any of those sources leads to chronic disease, as thousands of scientific studies have long proven. Therefore the only way to get enough calories to sustain a healthy body is to get the majority of them in the form of carbohydrates, ideally fresh fruits and vegetables. Ketosis is the body's "last resort" mechanism for survival. It technically can work in the short term but its only actual benefit is with treating epilepsy.

@Vunderbread 8 жыл бұрын

+traceler The reason he says that is because he gets his information from actual scientific journals, and not fad diet junk scientists.

@chrislecky710 2 жыл бұрын

Grey hair before the age it meant to appear is a mutation, your eye colour can similarly mutate. these are signs of ancient DNA..

@davo4000 2 жыл бұрын

The brain can use ketones and is a cleaner burn than glucose.

@LM-xs1qh 7 жыл бұрын

Brain only takes glucose? What about ketones?

@knr6293 Жыл бұрын

very poor audio

@carolempie114 3 жыл бұрын

The brain LOVES ketones and is the preferred energy source vs glucose. What’s up with this lack of knowledge? It makes me doubt the whole lecture.

@amanighamrawi583 2 жыл бұрын

You are awesome thank you

@OatmealTheCrazy 2 жыл бұрын

Look at the date

@gineisab9240 4 жыл бұрын

Traduction en français S.V.P

@aveng006 9 жыл бұрын

How do you test the rats memory?

@rayleneevans4166 7 жыл бұрын

With a maze. If they forget where the exit is, or if they can find it (again) fast.

@rooseveltbrown3rdandterrible Жыл бұрын

Creation not evolution

@adamsblanchard836 Жыл бұрын

Tip: discrepancy in description, tips were not of dindritic spines Dr. Sally....

@paulhand5015 2 жыл бұрын

articulate but some fundamentals wrong obligate glucose ... no new cells ....

@ceecee6679 2 жыл бұрын

Just here to see what the 'experts' say so I can do the opposite.

@prakashpatel1207 2 жыл бұрын

Summary is "we know NOTHING for sure"!!!

@martinirving3824 5 жыл бұрын

"Protein aggregation: neurodegenerative diseases." "Insidious onset. Gradual progression" Why, that sounds very similar to type 2 diabetes, aka, insulin resistance. (sarcasm intended). July, 2019.