Understanding The Gleason Score | Prostate Cancer Staging Guide

Рет қаралды 162,113

Күн бұрын

PCRI Executive Director, Mark Scholz, MD, explains how the Gleason Score works in prostate cancer.
Don’t know your stage? Take the quiz: Visit www.prostatecancerstaging.org
To learn more about prostate cancer visit www.pcri.org
To download the free Staging Guide visit www.pcri.org/prostate-cancer-s...
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website or call our free helpline at 1 (800) 641-7274 with any questions that you have. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
The information on the Prostate Cancer Research Institute's KZfaq channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.
#ProstateCancer #Prostate #MarkScholzMD

Пікірлер: 105

@adjeiboateng6720 20 күн бұрын

Such an informative video. Thank you Dr Mark😊

@catfish24 Жыл бұрын

Thank you for your knowledge and expertise in this field. I just had a prostate biopsy with 21 core samples and 2 of the samples came back positive my urologist said my Gleason score was a 6 He said i was more likely to be hit and killed by a car than for this score of 6 to do any harm. So he recommended just to keep monitoring me closely.

@Drmarwa213 2 жыл бұрын

I'm pepraring for a test , and it was difficult for me to understand the interprétation of this score , but After i watched this video it's very clear and easy ❤️ thank you

@michaelh2716 10 ай бұрын

I'm 69 y/o with a Gleason Score of 8. My PSA is 4.08 and had been steadily increasing from 2.22 since May 2021. I had a PET CT Scan that showed no METS! The Prostate Ca is localized in the Prostate! (Yeah!) I'll speak to a Radiation Oncologists & a Surgeon within a week (Aug 2023) and then decide which Tx to accept. Leaning toward Radiation, but want to hear from each Doctor first. Your videos have been VERY Helpful!

@haroldburris3781 8 ай бұрын

Which did you choose for treatment?

@michaelh2716 8 ай бұрын

@@haroldburris3781 Androgen Deprivation Therapy started & Radiation to start in December; 5 days/wk for 8-9 wks.

@adk346 4 жыл бұрын

Wow! Someone finally explained that! Thank you!

@TFreemanJohnson 11 ай бұрын

What constitutes an "acknowledged expert" pathologist? Does the term have a specific meaning? Is there some sort of certification credential to look for? If my surgeon says "Oh yeah, it was read by the best guy in the biz." Should I be satisfied with that assertion?

@TheMegaKidBoy 5 жыл бұрын

Thank you! Very clear explanation.

@graemeroberts2935 2 жыл бұрын

Excellent explanation, Dr. Scholz. Thank you!

@confidentlylost7215 3 жыл бұрын

Thank you so much for the comprehensive explanation sir

@dougirvine8615 3 жыл бұрын

Finally someone who can explain the Gleason scale that actually makes sense.....I love my Doctor but he spent twice as much time explaining it and left me confused...THANKS

@kenzonikolai1469 2 жыл бұрын

you all prolly dont give a shit but does someone know a tool to log back into an Instagram account?? I was stupid forgot my account password. I love any help you can offer me

@ariryder5473 2 жыл бұрын

@Kenzo Nikolai instablaster :)

@kenzonikolai1469 2 жыл бұрын

@Ari Ryder I really appreciate your reply. I got to the site through google and I'm trying it out now. Takes quite some time so I will get back to you later when my account password hopefully is recovered.

@kenzonikolai1469 2 жыл бұрын

@Ari Ryder it worked and I now got access to my account again. I am so happy! Thanks so much you saved my account !

@ariryder5473 2 жыл бұрын

@Kenzo Nikolai Glad I could help :)

@yb801 3 жыл бұрын

thank you, doctor, you explained very well.

@kunsadimitrios8266 2 жыл бұрын

Well explained, thanks so much Doctor.

@shreyasadhu8990 2 жыл бұрын

So crisp and to the point ! Thanku 😀

@pluedemann1 Жыл бұрын

Thank you Dr. Scholz for a very informative video. The way you presented the info was excellent and answered many of questions I had.

@PlastelAnimations 3 жыл бұрын

Thank you that is very clear and helpful !

@edwardbertorelli7358 Жыл бұрын

Great series of informative analysis..your commentary is enlightening..and your manner is open and welcoming. I've listened to most of your talks. Thanks... ..

@nicasiohernandez4099 3 жыл бұрын

Thank u so much for excellent explanation

@DivorceSourceRadio 2 жыл бұрын

Love everything about this channel. It's a shame you can't find this type of information at many urologists offices.

@canucksway Жыл бұрын

1. Fruits with lycopene - tomatoes, grapefruit, papaya apricots, watermelon, etc. 2. Fish & fish oil (Omega 3) 3. Citrus fruit - oranges, lemons 4. Nuts containing Zinc - cashews, peanuts, almonds 5. Brazil nuts (Selenium), vitamin D (salmon) or supplements 6. Olive oil, avocados and its oil, pistachios, dark chocolate 7. Allium vegetables: garlic and onions

@tonyroma7599 Жыл бұрын

thank you for putting this information out there.👍

@jefffarrenkopf2847 3 жыл бұрын

Excellent info!

@cfurrati 4 жыл бұрын

Congrats! Your video answered my doubts. Very good material. Watching from Brazil

@ThePCRI 4 жыл бұрын

Thank you for letting us know!

@chinchchinch9918 3 жыл бұрын

How are you doing now ?

@andrewbayram765 4 жыл бұрын

Good vid. My Dad got diagnosed then my older brother, then my younger brother. All 4 of us bloomed within a few years of each other. My Gleeson was a 3+4. My younger brothers was labelled as more aggressive. My older brother at this time was moving into the terminal phase. My dad had radio therapy and blazed through it all never missing a day at work(75 + years old). Ultimately due to my older brother dying and my younger brothers cancer being labelled more aggressive took the plunge and had my prostate removed. Things went well apart from the usual side effects of surgery. On follow up I was informed that my cancer had been of a more aggressive nature then my Gleeson score revealed. This was something not explained to me. Your video is spot on. Sometimes I question my decision to to do what others labelled as jump early and the lack of sensation and erections but knowing it was more aggressive then expected and having watched my older brother die horribly restored my faith I did the right thing.

@ThePCRI 4 жыл бұрын

Thank you for sharing your story, Andrew!

@i.w.y.3846 4 жыл бұрын

@john Heather Where can I go on the internet to read about !ROLLAND and his cancer cure?

@walidsarwary 3 жыл бұрын

Hi brother so your dad was diagnoses age 75 and than how old are you and your brothers whom got the cancer caz i am 36 and my father diagnosed age 70 but my older brother is 44 years old but he is fine and my other brother is 40 he has no symptoms i checked my prostate was fine should i be worried ?

@Melody-285 3 жыл бұрын

Andrew - how are you doing now ? Please don’t focus on what you’ve lost - if you’re alive with a reasonable quality of life, that’s what matters - I just lost a friend to prostate cancer and it was fast ....it had spread, but they were still saying it would be ok & 4 mos later, he’s gone -

@theophilusfrancis6276 2 жыл бұрын

@@walidsarwary ok

@khalidalhashmi709 4 жыл бұрын

thanks nicely explained

@razan.ag2 3 жыл бұрын

Thank you so much

@cattymed4419 5 жыл бұрын

thank you,,,, bailey and love was getting pretty confusing for me

@user-em3jx9rm1q 4 жыл бұрын

Fighting !!!!

@clowie299 5 жыл бұрын

good video

@getmore3521 2 жыл бұрын

Thank you 🙏

@ibnjameel97 2 жыл бұрын

Just Wow 🤩 ...Thanks a lot 😍

@markbrown5117 3 жыл бұрын

Thank u sir. U Rock.

@Mark-is6re 4 жыл бұрын

Outstanding explanation of a complicated topic!

@satvindermudan5006 3 жыл бұрын

Is he using grade and score synonymously? Is that the correct interpretation?

@Mark-is6re 3 жыл бұрын

@@satvindermudan5006 Hi Satvinder. Yes, same idea, just altered terms slightly.

@satvindermudan5006 3 жыл бұрын

@@Mark-is6re ok I understand. But surely that just adds to the confusion not reduce.

@fook12345 9 ай бұрын

thank you sir❤

@dingdong436. Жыл бұрын

Thank you 😍

@elsiethomas8793 2 жыл бұрын

Can the PSA reading guide regarding the Gleason score being 4+4=8 or 4+5=9. Will PSA reading be high or low if the gleadon score is low?

@davetheman2615 11 ай бұрын

thanks doc

@Invictus888 3 жыл бұрын

Excellent Video!

@CheriRichards 4 жыл бұрын

Excellent video thank you. A recent biopsy of a 58 year old loved one showed 8 of 12 samples tested positive. Gleason scores were: 1 @ 6; 5 @ 7 with 2 @ 8. Hence, we've been told it is an aggressive cancer. A subsequent full body bone scan with a nuclear isotope did not suggest the cancer has spread. We are very interested in obtaining a second opinion of these biopsy slides from a prostate pathology expert. Can you please advise on how we go about locating an expert to review these slides? We do like the Dr.'s we are working with though we want a completely independent second opinion from an expert. Thank you again.

@ThePCRI 4 жыл бұрын

Hello Cherise, thank you for sharing. Patient's often send their biopsy slides to Dr. Jonathan Epstein from John Hopkins University. He is an expert in prostate pathology. Here is Dr. Epstein's contact information: urology.jhu.edu/jonathanepstein/ pathology.jhu.edu/department/services/consults/urologic.cfm Also, here is an article he did for our website: pcri.org/insights-blog/2016/3/10/interpreting-a-pathology-report-15-biopsy-and-gleason-questions-answered-by-a-leading-pathologist?rq=Epstein

@ga20904 3 жыл бұрын

@@ThePCRI , good information I was about to ask the same question as to who can give a second opinion

@velko8026 2 жыл бұрын

How accurate is the blood test 4k score in Gleasons scale

@AnsweringMusic Жыл бұрын

What if someone had 12 samples cut, and out of those, only 3 showed cancer. But the 3 that showed were “high risk”. Is this still a good sign providing there were only 3 positive and 9 that didn’t not have cancer? What could the stage be? What is the chance of survival?

@anthonymiller6081 Жыл бұрын

I live in Australia so I'm not sure how different it is to the United States. It's now 2023 and I'm currently waiting to have a Biopsy done on my prostate. I'm not in the private health system (insurance) here in Australia unfortunately. I'm in the Govt public hospital system which is normally good and most private urologists work in both anyway. The only difference with private it you may probably choose who you want and probably get it done quicker. I can use the private specialist but I have to pay about $4000 here in Australia for a prostate biopsy but it's free in the Govt system. I might have wait 1,2, 3 or more weeks which is ridiculous considering it's important to know what your actually dealing with. Hope it's not like that in the USA

@vladlungu3033 2 жыл бұрын

The result of my Biopsy test is : total Gleason Score - 7 (3+4); Grade group - 2; total number ofcores : 12 ; Positive : 4 ; offered treatment : Radical prostatectomy, and Radiation therapy. I have one month for making of desicion, I am confused what to do ? Your opinion please, what vould you do in this situation?

@ThePCRI 2 жыл бұрын

Vlad, You are welcome to get in touch with our free helpline here: pcri.org/helpline

@keshabnayak Жыл бұрын

So what you have done. Are you good and healhty

@kihi2608 Жыл бұрын

Hi doctor First of all thank you for your information. My Gleason's is III+III=6 TOTAL PSA IS 9.3 FREE PSA IS 2.39 Transial zone:PIRADS 2 PERIPHERAL zone:PIRADS 4 PLEASE inform me for choosing what kind of treatment surgery or trapy .. Thank you so much for helping Dr. Age: 61 years

@keshabnayak Жыл бұрын

Did you under went any kind of surgery

@kihi2608 Жыл бұрын

@@keshabnayak No i didn't went under surgery yet.last MY PAS decreasing from 9.3 to 6.o6

@faragelabeidi186 6 ай бұрын

What's the best treatment for 3+3,grade I...., age 74,post open heart surgery, PSA 34 ng/ml

@flmoseley8141 2 жыл бұрын

I have a gleason score of 6 or Epstein 1. I've already had 2 biopsies that truly suck cause they dont put you under and then you ejaculate blood for 2 months. I was told by my urologist that they hardly call my prostate cancer a cancer and its non aggressive. I'm 60 and now they want to do another biopsy and my psa has gone down from 7 to a 5. My feeling is if I keep getting biopsies where they jab a needle in there 12 to 14 times sooner or later I'm gonna get an infection or they will inadvertantly prelease cancer cells in my body that would never have escaped the prostate in my lifetime. So I've cancelled that 3rd biopsy at least for now. Any thoughts on this?

@larbearplays3904 2 жыл бұрын

My psa went from a 3.74 to 3 months later a 6.28 and 2 months later a 9.74 One hospital wanted to remove prostate and would not allow me to decide on other treatment. I went to a national cancer specific hospital (Roswell) and they have giving me 3 options. 1) surgical removal, 2) radiation, and 3) chemo. I go in again in a few days for bone scan with and without dye in a few weeks. I already 100% am against surgical removal as I like you don't want it spreading due to surgical intervention. Let's just say "family history" has put the belief o the surgery causing it to spread and dieng of cancer firmly in my head. As for advise, go with your heart, beliefs, and input from knowledgeable sources. Mine has went from intermediate to aggressive. Sorry if I was of no help to you. However I wish you the very best outcome. 55 yrs old, diagnosed at 54.

@jayevans7894 3 жыл бұрын

My father got diagnosed in feb this year, surgery wasn’t offered to him. He’s started hormone therapy and will start radium at the end of August. What will happen after he finishes radium?

@jayevans7894 3 жыл бұрын

Mike Tucker thank you for your reply mr tucker. Yes I mean radiation therapy but in the uk we shorten it to radium. I’m absolutely over the moon that your cured and get to live a long happy life. My father is 67 and I’m praying that this radiation will kill the cancer. I’ll let you know how he gets on. He starts end of August

@ThePCRI 3 жыл бұрын

Hello, our prostate cancer helpline may be able to help with your question. Please feel free to contact us here: pcri.org/helpline

@Melody-285 3 жыл бұрын

@Nomad just reading your wonderful post - I just lost a dear friend to prostate cancer - his had metastasized & it seemed like he went down so fast .... I hope you’re still good - warmest wishes to you 😊

@papaormsby874 3 жыл бұрын

I would like a PSA score at what number does it leak to other places??

@ThePCRI 3 жыл бұрын

Hello, the patient advocate who runs our helpline may be able to help with your question. Contact us using this page: pcri.org/helpline

@King_Illuminaughti Жыл бұрын

No I think we get it❣️🙏🏻

@canucksway Жыл бұрын

Tomatoes are the fourth most commonly consumed fresh vegetable and the most frequently consumed canned vegetable in the American diet. There is emerging epidemiology data supporting the connection between increased tomato consumption and reduced risk for both cardiovascular disease and prostate cancer. Here we will summarize the nutrient and the phytochemical content of tomatoes and tomato products, and how these bioactive components might act together to modulate disease development. Recent animal studies have investigated tomatoes, lycopene, and prostate cancer using the N-methyl-N-nitrosourea and Dunning rat models. These animal studies also suggest that diets containing tomatoes may decrease the risk or the progression of prostate cancer. Due to the frequency and the extent of tomato consumption, the supporting epidemiological and animal data, which connect increased intakes with decreased cancer and cardiovascular disease risk, tomato's role in the American diet is of undeniable importance as part of a healthy diet.

@Dr.Crabsticks 3 жыл бұрын

Could you score a prostate cancer 1+5 = 6? Or is 3+3=6 the “lowest” combination

@ThePCRI 3 жыл бұрын

Hello, our prostate cancer helpline may be able to help with your question. Please feel free to contact us here: pcri.org/helpline

@rogerembry4777 2 жыл бұрын

Psa 2.9 Gleason 9

@foodislifesouthafricacapet3716 2 жыл бұрын

Hi how far has yours spread? My husband a Gleason 9 but PSA 132 before hormone.. going back for PSA on the 1st August

@greyg1537 2 жыл бұрын

Thankyou sir🙏

@DedaAlshebani 8 ай бұрын

it was difficult for st 5th medical study

@robd2650 2 жыл бұрын

I wonder how you can make sure your slides get read with the best expertise? I mean are the slides in you possession? Do you say to the place I don't trust the way you read the slides? I mean I agree with him, that this is probably an issue, but you wouldn't think this would be something you'd have to take into your own hands. You'd think if they're medicals professionals doing all of this, they're would be safe guards in place to make sure the readings are correct.

@ThePCRI 2 жыл бұрын

Rob, There are a few good options for second opinions on pathology, but Jonathan Epstein, MD, at Johns Hopkins is one of the most favored by Dr. Scholz. Here is a link to his second-opinion program: pathology.jhu.edu/patient-care/second-opinions/send Your medical institution should send the slides without you needing to handle them yourself, and they should not be too offended - some insurances and institutions actually require a second opinion just to be sure.

@user-um6eb3ek2z 2 жыл бұрын

i enjoyed your lecture before taking radiotherapy...THANK gods anyone who know you!

@jamesadamgleason9471 Жыл бұрын

37yo Male with an enlarged prostate. I'm searching for answers and then this pops up. My last name is Gleason, I'm officially scared.

@majaarminovska8026 8 ай бұрын

Can i have your email for consultation, thanks 🙏

@jhodini 2 жыл бұрын

"Other Inforamation in the Pathology Report" (3:49). Small typo, I believe. Does not reflect well when presenting such a serious subject.

@ThePCRI 2 жыл бұрын

Yeah, we noticed that but could not fix it without reuploading the entire video, which would make all of our other videos out of order. It was published when we had a smaller, busier, staff, so typos may have slipped through more often, but we will be updating the entire staging guide series in the near future, and we will remove this video. Until then, I hope the typo does not affect the quality of the information too much for you.

@calbob750 2 жыл бұрын

So much focus on PSA numbers. The Gleason Score tells it like it is.IMO.

@georgeschoombie4316 2 жыл бұрын

I still don't understand it please explain it

@keithwilson6060 4 жыл бұрын

What if a minimal Gleason score of 3+3 is accompanied by a steady increase in PSA levels?

@ThePCRI 4 жыл бұрын

Hi, our prostate cancer helpline may be able to answer your questions and help you find helpful information. Please feel free to contact us here: pcri.org/helpline

@cathum 3 жыл бұрын

Prostate Cancer Research Institute: The helpline telephone is not available for Canada; thanks.

@ncvman 7 ай бұрын

Get mri first then target biopsy. The other way around is a waste of time. Dumb insurance may not cover mri first though.

@RAZ112652 8 ай бұрын

Thank you for the very detailed explanation. However, the individual that reviews your videos should be careful of misspelled words in each of the subtitles for the various sections. I am a retired teacher and when I see such errors, it decreases the trust in the professionalism of the material presented.