Immunology Lecture 16 - Type IV Hypersensitivity Reactions

Рет қаралды 68,362

10 жыл бұрын

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This lecture covers T cell-mediated delayed hypersensitivity reaction (Type IV). Sensitized T cells release cytokines that activate macrophages and act as chemotactic agents for inflammatory cells. Issues like Type I Diabetes Mellitus, Multiple Sclerosis, Guillain Barre Syndrome, Hashimoto's thyroiditis, Graft vs host, contact dermatitis and PPD are talked about. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

Пікірлер: 84

@MrNima1997 6 жыл бұрын

This is the best video regarding type 4 hypersensitivity! Thank you!

@eddiedann6472 3 жыл бұрын

Fantastic!!!! Thank u n God Bless u n ur loved ones. 👏👏👏

@hothpalpanom4410 5 жыл бұрын

thank you dr and i hope my presentation on type four will go better you really sacrifice.you are hero

@hotshitattitude 3 жыл бұрын

Dr. Syed, thank you for the helpful video! Just an aside, your handwriting is beautiful.

@lindanguyen6108 8 жыл бұрын

You sir, are an excellent educator.

@subhashchandrajangir3749 8 жыл бұрын

most clear concept.. make very nice......thanks sir

@abbassyednhs 9 жыл бұрын

Amazing Dr Mobeen

@hafsamushtaq7677 3 жыл бұрын

Mind blowing..It is Very helpfull lecture

@siddhidesai6532 9 жыл бұрын

Thank you. Helpful and quite in deapth.

@sejal6329 5 жыл бұрын

thankyou so much. god bless you!!

@Salma-baeisa 4 жыл бұрын

You are just amazing thank you so much god bless you

@ozz530 10 жыл бұрын

Thank you and God Bless

@tanimasasmal4081 2 жыл бұрын

Sir, please make a complete details video on 'polyclonal and monoclonal antibody "for exam. All this video on ' hypersensitivity reaction' helps me a lot. Thanks to you for this.

@safiullahrahmani5492 7 жыл бұрын

Thank you Sir...it was super

@adityadhand476 7 жыл бұрын

Marvellous job sir ! Respect

@DrBeenMedicalLectures 7 жыл бұрын

Thank you. Find more lectures on drbeen.com.

@dnabiology6659 6 жыл бұрын

Very nice teaching sir thanku very much keep it up god work for students

@DrBeenMedicalLectures 9 жыл бұрын

Bokan sb: you are correct MS affects white matter of the CNS. These are Oligodendrocytes.

@megwilson9627 9 жыл бұрын

hi, was just wondering if B cells would be involved in any aspect of this immune reaction? I understand that antibodies are not produced but do the B cells act in any other ways?

@vivekdadhania 9 жыл бұрын

Awesome! Thank you.

@DrBeenMedicalLectures 9 жыл бұрын

You are welcome!

@Elly3121 9 жыл бұрын

Thank you Dr. Mobeen

@DrBeenMedicalLectures 9 жыл бұрын

You are welcome!

@pd1296 9 жыл бұрын

In Type 1 DM and MS, can i say that the lymphoctes are sensitised in the first exposure to the islet of langerhans or schwanna cells. then they become memory lymphocytes and they just attack these cells again? So does this mean that memory lymphocytes can straight bind to the antigen and does not need any help from APC?

@anjidodiya4675 6 жыл бұрын

Superb sir nice explaination

@Scully69 9 жыл бұрын

very very well structured! i really enjoyed it! have you ever considered doing more pathophys / pharma? ;)

@saynabmohamud6891 6 жыл бұрын

Thanks drbeen, very good explanation

@DrBeenMedicalLectures 6 жыл бұрын

Pleasure. Check drbeen.com for more lectures.

@dr.niteshpandey3096 4 жыл бұрын

Is der any specific pathogen for multiple sclerosis? like for tuberculosis myobacterium wich goes into the body n causes this reaction

@reemalotaibi6506 6 жыл бұрын

thanks a lot ... it was helpfull

@sanaayunus4209 7 жыл бұрын

seriously u teach in the best way..😊 thanks alote for the video

@DrBeenMedicalLectures 7 жыл бұрын

Good to know. There are more lectures to keep you happy. Visit: www.drbeen.com/catalog

@DrBeenMedicalLectures 7 жыл бұрын

Glad that you like our teaching. Please find more videos on www.drbeen.com/catalog Best Mobeen

@adityamalladi1157 9 жыл бұрын

very clear. thank u so much.

@DrBeenMedicalLectures 9 жыл бұрын

aditya malladi you are welcome!

@sabamalik1004 6 жыл бұрын

Thanku much Sir for hypersensitivity lectures.. these helped alot .. thanku once again

@DrBeenMedicalLectures 6 жыл бұрын

My pleasure. Check out drbeen.com for more lectures.

@atifjan70 7 жыл бұрын

Very interesting teaching thank you so much, have u made any video on Serology tests?

@DrBeenMedicalLectures 7 жыл бұрын

Not yet.

@saishannu 6 жыл бұрын

Sir, Please upload a lecture on coagulation cascade and coagulation tests integrated within. Thank you Sir. Expecting a positive response.

@EvasiveEvo 7 жыл бұрын

guillean barre is a type 2 hypersensitivity due to antigenic similiaruty to camplobacter.

@enadmohamed5433 9 жыл бұрын

thank you so much . you are really great doctor

@DrBeenMedicalLectures 9 жыл бұрын

Thank you!

@tulasazenith951 3 жыл бұрын

Thank you sir🥰🥰😊

@ahmadadam1044 7 жыл бұрын

Thank you very much u are indeed great

@DrBeenMedicalLectures 7 жыл бұрын

You are most welcome. Study well and continue being the best! Check drbeen.com for more lectures.

@md.mahamudunnobimahmud7774 9 жыл бұрын

Sir,which one is for T Cell-mediated Cellular Immunity?

@ramshaijaz5169 5 жыл бұрын

Will you plz upload type 2 hyper sensitivity?

@awaismehmood690 5 жыл бұрын

Very very informative and knowledgeable

@DrBeenMedicalLectures 5 жыл бұрын

Thank you!

@beautyamy2487 8 жыл бұрын

Thank you very much doctor mobeen ., please is there a video about hypersensitivite type 1 and 2 !!!?

@DrBeenMedicalLectures 8 жыл бұрын

+imane amy yes. Check in the videos or visit drbeen.com and go to immunology module (it is free). There you will find all videos in a list.

@jordylarco3744 8 жыл бұрын

Where do you find the informations? in which book can i find it ??

@Solo.Gr8 8 жыл бұрын

hello dr saab..i have a query in delayed hyper sensitivity reaction when cd4 is activated by antigen presenting cells (like in case of tuberculin test) they became sensitive and wait for the antigen to re enter the body. why they don't follow the tradianal path like garbbing the tuberculin molecule presenting the antigen to b cells and provoke a humoral response instead of cell mediated and damaging the tissue by casies necros? and thank you for your contributions

@DrBeenMedicalLectures 8 жыл бұрын

+Sulaiman Gran it is not that the cells will only work through one pathway. It is the predominance of the result. All mechanisms that can engage in a given situation do become engaged. Some are more effective than others.

@Tommytorque69 4 жыл бұрын

My father has a pet Parakeet that he is now living with for 4 years. Recently this year he was diagnosed with pulmonary fibrosis. So are you saying that the Parakeet is the culprit and that he should get rid of the poor little bird? Thank you.

@DrBeenMedicalLectures 10 жыл бұрын

vwziful - could not reply to your post. Something with this new commenting system prevents me from replying to your post. Hope you can read this comment: I am talking about the blistering due to contact with chemical substances or plants.

@22inominata 8 жыл бұрын

MS = demyelination of oligodendrocytes GBS = demyelination of schwann cells

@MedManiac1 7 жыл бұрын

superb

@DrBeenMedicalLectures 7 жыл бұрын

Thanks

@manjarichaudhary5400 6 жыл бұрын

I really gone fan of u sir

@DrBeenMedicalLectures 6 жыл бұрын

Thank you, dear. Study well.

@Guiltfreedelight 6 жыл бұрын

sir, type 1 diabetes is disease which is due to type 4 hypersensitivity section- intracellular pathogenic antigen where macrophage activates T1cell which in turn activates macrophage by IL12 and IFN gamma cycle and cause damage to tissue. ok but what is the pathogen here?

@DrBeenMedicalLectures 6 жыл бұрын

No pathogen is involved for type 1 DM.

@dG_Danga 6 жыл бұрын

Sir ,,,make a video about type2 hypersensitivity pls

@vwziful 10 жыл бұрын

but blistering in pemphigoid vulgaris and bullous phemphigus is type 2??

@aakashsharma7340 8 жыл бұрын

thank u so much sir...can u plz upload hypersensitivity 2 lecture as well :)

@DrBeenMedicalLectures 8 жыл бұрын

+aakash sharma will do!

@bibekbastakoti5290 4 жыл бұрын

Dr what about costimulus for Cytotoxic T cell activation in Contact Dermatitis? Can killer T cell function properly without co-stimulus Il-2 ???

@HimanshuKumar-dv6nb 4 жыл бұрын

Co stimuli is not needed for killing function, it is only required to activate CD8+ T cell

@HimanshuKumar-dv6nb 4 жыл бұрын

He is actually talking about memory cytotoxic t cell in skin formed after primary exposure the work in kind of same way as memory B cells they also don't need costimulation for activation